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  • Sabine Matallana-Surget
    University of Stirling
  • Johannes Werner
    Leibniz Institute of Baltic Sea Research, Rostock, Germany
  • Ruddy Wattiez
    University of Mons, Belgium
  • Karine Lebaron
    University of Stirling
  • Laurent Intertaglia
    Sorbonne Universités
  • Callum Regan
    University of Stirling
  • James Morris
    University of Stirling
  • Hanno Teeling
    Max Planck Institute for Marine Microbiology, Bremen
  • Manuel Ferrer
    CSIC, Institute of Catalysis, Madrid, Spain.
  • Peter Golyshin
  • Dimitrios Gerogiorgis
    University of Edinburgh
  • Simon I. Reilly
    Bangor University
  • Philippe Lebaron
    Sorbonne Universités
Epibacterium mobile BBCC367 is a marine bacterium that is common in coastal areas. It belongs to the Roseobacter clade, a widespread group in pelagic marine ecosystems. Species of the Roseobacter clade are regularly used as models to understand the evolution and physiological adaptability of generalist bacteria. E. mobile BBCC367 comprises two chromosomes and two plasmids. We used gel-free shotgun proteomics to assess its protein expression under 16 different conditions, including stress factors such as elevated temperature, nutrient limitation, high metal concentration, and UVB exposure. Comparison of the different conditions allowed us not only to retrieve almost 70% of the predicted proteins, but also to define three main protein assemblages: 584 essential core proteins, 2,144 facultative accessory proteins and 355 specific unique proteins. While the core proteome mainly exhibited proteins involved in essential functions to sustain life such as DNA, amino acids, carbohydrates, cofactors, vitamins and lipids metabolisms, the accessory and unique proteomes revealed a more specific adaptation with the expression of stress-related proteins, such as DNA repair proteins (accessory proteome), transcription regulators and a significant predominance of transporters (unique proteome). Our study provides insights into how E. mobile BBCC367 adapts to environmental changes and copes with diverse stresses.
Original languageEnglish
Article number3125
JournalFrontiers in Microbiology
Early online date21 Dec 2018
Publication statusPublished - Dec 2018

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