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Real-time detection of DNA interactions with long-period fiber-grating-based biosensor

Research output: Contribution to journal › Article › peer-review

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Real-time detection of DNA interactions with long-period fiber-grating-based biosensor. / Chen, Xianfeng; Zhang, L.; Zhou, K. et al.
In: Optics Letters, Vol. 32, No. 17, 09.2007, p. 2541-2543.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Chen, X, Zhang, L, Zhou, K, Davies, E, Sugden, K, Bennion, I, Hughes, M & Hine, AV 2007, 'Real-time detection of DNA interactions with long-period fiber-grating-based biosensor', Optics Letters, vol. 32, no. 17, pp. 2541-2543. https://doi.org/10.1364/OL.32.002541

APA

Chen, X., Zhang, L., Zhou, K., Davies, E., Sugden, K., Bennion, I., Hughes, M., & Hine, A. V. (2007). Real-time detection of DNA interactions with long-period fiber-grating-based biosensor. Optics Letters, 32(17), 2541-2543. https://doi.org/10.1364/OL.32.002541

CBE

Chen X, Zhang L, Zhou K, Davies E, Sugden K, Bennion I, Hughes M, Hine AV. 2007. Real-time detection of DNA interactions with long-period fiber-grating-based biosensor. Optics Letters. 32(17):2541-2543. https://doi.org/10.1364/OL.32.002541

MLA

Chen, Xianfeng et al. "Real-time detection of DNA interactions with long-period fiber-grating-based biosensor". Optics Letters. 2007, 32(17). 2541-2543. https://doi.org/10.1364/OL.32.002541

VancouverVancouver

Chen X, Zhang L, Zhou K, Davies E, Sugden K, Bennion I et al. Real-time detection of DNA interactions with long-period fiber-grating-based biosensor. Optics Letters. 2007 Sept;32(17):2541-2543. doi: 10.1364/OL.32.002541

Author

Chen, Xianfeng ; Zhang, L. ; Zhou, K. et al. / Real-time detection of DNA interactions with long-period fiber-grating-based biosensor. In: Optics Letters. 2007 ; Vol. 32, No. 17. pp. 2541-2543.

RIS

TY - JOUR

T1 - Real-time detection of DNA interactions with long-period fiber-grating-based biosensor

AU - Chen, Xianfeng

AU - Zhang, L.

AU - Zhou, K.

AU - Davies, E.

AU - Sugden, K.

AU - Bennion, I.

AU - Hughes, M.

AU - Hine, A.V.

PY - 2007/9

Y1 - 2007/9

N2 - Using an optical biosensor based on a dual-peak long-period fiber grating, we have demonstrated the detection of interactions between biomolecules in real time. Silanization of the grating surface was successfully realized for the covalent immobilization of probe DNA, which was subsequently hybridized with the complementary target DNA sequence. It is interesting to note that the DNA biosensor was reusable after being stripped off the hybridized target DNA from the grating surface, demonstrating a function of multiple usability.

AB - Using an optical biosensor based on a dual-peak long-period fiber grating, we have demonstrated the detection of interactions between biomolecules in real time. Silanization of the grating surface was successfully realized for the covalent immobilization of probe DNA, which was subsequently hybridized with the complementary target DNA sequence. It is interesting to note that the DNA biosensor was reusable after being stripped off the hybridized target DNA from the grating surface, demonstrating a function of multiple usability.

U2 - 10.1364/OL.32.002541

DO - 10.1364/OL.32.002541

M3 - Article

VL - 32

SP - 2541

EP - 2543

JO - Optics Letters

JF - Optics Letters

SN - 0146-9592

IS - 17

ER -