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Scaling-up Engineering Biology for Enhanced Environmental Solutions

Research output: Contribution to journal › Article › peer-review

Standard Standard

Scaling-up Engineering Biology for Enhanced Environmental Solutions. / Hassard, Francis; Curtis, Thomas P; Dotro, Gabriela C et al.
In: ACS synthetic biology, Vol. 13, No. 6, 21.06.2024, p. 1586-1588.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Hassard, F, Curtis, TP, Dotro, GC, Golyshin, P, Gutierrez, T, Heaven, S, Horsfall, L, Jefferson, B, Jones, DL, Krasnogor, N, Kumar, V, Lea-Smith, DJ, Le Corre Pidou, K, Liu, Y, Lyu, T, McCarthy, RR, McKew, B, Smith, C, Yakunin, A, Yang, Z, Zhang, Y & Coulon, F 2024, 'Scaling-up Engineering Biology for Enhanced Environmental Solutions', ACS synthetic biology, vol. 13, no. 6, pp. 1586-1588. https://doi.org/10.1021/acssynbio.4c00292

APA

Hassard, F., Curtis, T. P., Dotro, G. C., Golyshin, P., Gutierrez, T., Heaven, S., Horsfall, L., Jefferson, B., Jones, D. L., Krasnogor, N., Kumar, V., Lea-Smith, D. J., Le Corre Pidou, K., Liu, Y., Lyu, T., McCarthy, R. R., McKew, B., Smith, C., Yakunin, A., ... Coulon, F. (2024). Scaling-up Engineering Biology for Enhanced Environmental Solutions. ACS synthetic biology, 13(6), 1586-1588. Advance online publication. https://doi.org/10.1021/acssynbio.4c00292

CBE

Hassard F, Curtis TP, Dotro GC, Golyshin P, Gutierrez T, Heaven S, Horsfall L, Jefferson B, Jones DL, Krasnogor N, et al. 2024. Scaling-up Engineering Biology for Enhanced Environmental Solutions. ACS synthetic biology. 13(6):1586-1588. https://doi.org/10.1021/acssynbio.4c00292

MLA

Hassard, Francis et al. "Scaling-up Engineering Biology for Enhanced Environmental Solutions". ACS synthetic biology. 2024, 13(6). 1586-1588. https://doi.org/10.1021/acssynbio.4c00292

VancouverVancouver

Hassard F, Curtis TP, Dotro GC, Golyshin P, Gutierrez T, Heaven S et al. Scaling-up Engineering Biology for Enhanced Environmental Solutions. ACS synthetic biology. 2024 Jun 21;13(6):1586-1588. Epub 2024 Jun 21. doi: 10.1021/acssynbio.4c00292

Author

Hassard, Francis ; Curtis, Thomas P ; Dotro, Gabriela C et al. / Scaling-up Engineering Biology for Enhanced Environmental Solutions. In: ACS synthetic biology. 2024 ; Vol. 13, No. 6. pp. 1586-1588.

RIS

TY - JOUR

T1 - Scaling-up Engineering Biology for Enhanced Environmental Solutions

AU - Hassard, Francis

AU - Curtis, Thomas P

AU - Dotro, Gabriela C

AU - Golyshin, Peter

AU - Gutierrez, Tony

AU - Heaven, Sonia

AU - Horsfall, Louise

AU - Jefferson, Bruce

AU - Jones, Davey L

AU - Krasnogor, Natalio

AU - Kumar, Vinod

AU - Lea-Smith, David J

AU - Le Corre Pidou, Kristell

AU - Liu, Yongqiang

AU - Lyu, Tao

AU - McCarthy, Ronan R

AU - McKew, Boyd

AU - Smith, Cindy

AU - Yakunin, Alexander

AU - Yang, Zhugen

AU - Zhang, Yue

AU - Coulon, Frederic

PY - 2024/6/21

Y1 - 2024/6/21

N2 - Synthetic biology (SynBio) offers transformative solutions for addressing environmental challenges by engineering organisms capable of degrading pollutants, enhancing carbon sequestration, and valorizing waste (Figure 1). These innovations hold the potential to revolutionize bioremediation strategies, ecosystem restoration, and sustainable environmental management. (1) Advances in SynBio, including automation, precise manipulation of genetic material, (2) and design of semisynthetic organisms with enhanced capabilities, can improve the efficiency of microbes for eliminating pollutants such as hydrocarbons and plastics or extracting valuable resources from the environment. (3) Genome editing technologies, such as CRISPR-Cas9, allows the editing of genomes with unprecedented accuracy, facilitating the development of organisms with desired traits or functions. (4) Furthermore, SynBio encompasses the engineering of metabolic enzymes within organisms, leading to the design of microbial factories capable of degrading complex and persistent chemicals, and converting waste to valuable resources. (5) These advancements also facilitate the manipulation of bacterial social behaviors, offering the capacity for tunable control at the multicellular level and engineered biofilms. (5)

AB - Synthetic biology (SynBio) offers transformative solutions for addressing environmental challenges by engineering organisms capable of degrading pollutants, enhancing carbon sequestration, and valorizing waste (Figure 1). These innovations hold the potential to revolutionize bioremediation strategies, ecosystem restoration, and sustainable environmental management. (1) Advances in SynBio, including automation, precise manipulation of genetic material, (2) and design of semisynthetic organisms with enhanced capabilities, can improve the efficiency of microbes for eliminating pollutants such as hydrocarbons and plastics or extracting valuable resources from the environment. (3) Genome editing technologies, such as CRISPR-Cas9, allows the editing of genomes with unprecedented accuracy, facilitating the development of organisms with desired traits or functions. (4) Furthermore, SynBio encompasses the engineering of metabolic enzymes within organisms, leading to the design of microbial factories capable of degrading complex and persistent chemicals, and converting waste to valuable resources. (5) These advancements also facilitate the manipulation of bacterial social behaviors, offering the capacity for tunable control at the multicellular level and engineered biofilms. (5)

KW - Synthetic Biology/methods

U2 - 10.1021/acssynbio.4c00292

DO - 10.1021/acssynbio.4c00292

M3 - Article

C2 - 38903005

VL - 13

SP - 1586

EP - 1588

JO - ACS synthetic biology

JF - ACS synthetic biology

SN - 2161-5063

IS - 6

ER -