The synthesis of both enantiomers of lactobacillic acid and mycolic acid analogues.
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In: Tetrahedron Letters, Vol. 40, No. 36, 03.09.1999, p. 6689-6692.
Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - The synthesis of both enantiomers of lactobacillic acid and mycolic acid analogues.
AU - Coxon, GD
AU - Knobl, S
AU - Roberts, E
AU - Baird, MS
AU - Al Dulayymi, JR
AU - Besra, GS
AU - Brennan, PJ
AU - Minnikin, DE
PY - 1999/9/3
Y1 - 1999/9/3
N2 - (11R, 12S)-lactobacillic acid (1) has been prepared either from D-mannitol by asymmetric cyclopropanation or from cycyclopropane-1, 2-dimethanol by enzymatic desymmetrisation. The syntheses of (11S, 12R)-lactobacillic acid (2) and (1R, 2S) 1(3'-methoxycarbonylpropyl)-2-octadecylcopropane (26) and related analogues (27 and 28) have also been achieved. (C) 1999 Elsevier Science Ltd. All rights reserved.
AB - (11R, 12S)-lactobacillic acid (1) has been prepared either from D-mannitol by asymmetric cyclopropanation or from cycyclopropane-1, 2-dimethanol by enzymatic desymmetrisation. The syntheses of (11S, 12R)-lactobacillic acid (2) and (1R, 2S) 1(3'-methoxycarbonylpropyl)-2-octadecylcopropane (26) and related analogues (27 and 28) have also been achieved. (C) 1999 Elsevier Science Ltd. All rights reserved.
U2 - 10.1016/S0040-4039(99)01378-7
DO - 10.1016/S0040-4039(99)01378-7
M3 - Article
VL - 40
SP - 6689
EP - 6692
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 36
ER -