Translin-Trax: Considerations for Oncological Therapeutic Targeting
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Fersiynau electronig
Dolenni
Dangosydd eitem ddigidol (DOI)
Dicer-deficient cancers have poor prognoses, which is linked to the degradation of tumour-suppressing miRNA precursors by the Translin-Trax (Tn-Tx) ribonuclease. Inhibition of Tn-Tx potentially offers a new therapeutic intervention point. However, Tn-Tx functions in an array of biological processes, and here we consider how this complexity could influence therapeutic design strategies.
Allweddeiriau
| Iaith wreiddiol | Saesneg |
|---|---|
| Tudalennau (o-i) | 450-453 |
| Nifer y tudalennau | 4 |
| Cyfnodolyn | Trends in Cancer |
| Cyfrol | 6 |
| Rhif y cyfnodolyn | 6 |
| Dyddiad ar-lein cynnar | 16 Maw 2020 |
| Dynodwyr Gwrthrych Digidol (DOIs) | |
| Statws | Cyhoeddwyd - Meh 2020 |