Translin-Trax: Considerations for Oncological Therapeutic Targeting

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

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Dangosydd eitem ddigidol (DOI)

Dicer-deficient cancers have poor prognoses, which is linked to the degradation of tumour-suppressing miRNA precursors by the Translin-Trax (Tn-Tx) ribonuclease. Inhibition of Tn-Tx potentially offers a new therapeutic intervention point. However, Tn-Tx functions in an array of biological processes, and here we consider how this complexity could influence therapeutic design strategies.

Allweddeiriau

Iaith wreiddiolSaesneg
Tudalennau (o-i)450-453
Nifer y tudalennau4
CyfnodolynTrends in Cancer
Cyfrol6
Rhif y cyfnodolyn6
Dyddiad ar-lein cynnar16 Maw 2020
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - Meh 2020
Gweld graff cysylltiadau