Professor Alexander Yakunin

Professor In Enzyme Discovery and Application

Contact info

 

Professor Alexander Yakunin (Iakounine)

 

Office: Thoday Building, room S25

Email: a.iakounine@bangor.ac.uk

Tel: 01248 388399

 

Research focus: enzyme discovery, enzymology, enzyme applications

  1. Article › Research › Peer-reviewed
  2. Published

    Proteome cold-shock response in the extremely acidophilic archaeon, Cuniculiplasma divulgatum

    Bargiela, R., Lanthaler, K., Potter, C., Ferrer, M., Yakunin, A., Paizs, B., Golyshin, P. & Golyshina, O., 19 May 2020, In: Microorganisms . 8, 5

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Relationships between Substrate Promiscuity and Chiral Selectivity of Esterases from Phylogenetically and Environmentally Diverse Microorganisms

    Coscolín, C., Martínez-Martínez, M., Chow, J., Bargiela, R., García-Moyano, A., Bjerga, G. E. K., Bollinger, A., Stokke, R., Steen, I. H., Golyshina, O., Yakimov, M. M., Jaeger, K-E., Yakunin, A. F., Streit, W. R., Golyshin, P. & Ferrer, M., 5 Jan 2018, In: Catalysts. 8, 1, 10.

    Research output: Contribution to journalArticlepeer-review

  4. SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia

    Schneider, C., Oellerich, T., Baldauf, H-M., Schwarz, S-M., Thomas, D., Flick, R., Bohnenberger, H., Kaderali, L., Stegmann, L., Cremer, A., Martin, M., Lohmeyer, J., Michaelis, M., Hornung, V., Schliemann, C., Berdel, W. E., Hartmann, W., Wardelmann, E., Comoglio, F., Hansmann, M-L., Yakunin, A. F., Geisslinger, G., Stroebel, P., Ferreiros, N., Serve, H., Keppler, O. T. & Cinatl, J. J., Feb 2017, In: Nature Medicine. 23, 2, p. 250-255

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Screening and Characterization of Novel Polyesterases from Environmental Metagenomes with High Hydrolytic Activity against Synthetic Polyesters

    Hajighasemi, M., Tchigvintsev, A., Nocek, B., Flick, R., Popovic, A., Hai, T., Khusnutdinova, A. N., Brown, G., Xu, X., Cui, H., Anstett, J., Chernikova, T., Bruls, T., Le Paslier, D., Yakimov, M. M., Joachimiak, A., Golyshina, O., Savchenko, A., Golyshin, P., Edwards, E. A. & Yakunin, A. F., 6 Nov 2018, In: Environmental Science and Technology. 52, 21, p. 12388-12401

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Site-directed mutagenesis and stability of the carboxylic acid reductase MAB4714 from Mycobacterium abscessus

    Fedorchuk, T. P., Khusnutdinova, A. N., Flick, R. & Yakunin, A., 10 Sept 2019, In: Journal of Biotechnology. 303, p. 72-79

    Research output: Contribution to journalArticlepeer-review

  7. Structural Insights into Substrate Selectivity and Activity of Bacterial Polyphosphate Kinases

    Nocek, B. P., Khusnutdinova, A. N., Ruszkowski, M., Flick, R., Burda, M., Batyrova, K., Brown, G., Mucha, A., Joachimiak, A., Berlicki, L. & Yakunin, A. F., 2 Nov 2018, In: ACS Catalysis. 8, 11, p. 10746-10760

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Structural and biochemical insights into CRISPR RNA processing by the Cas5c ribonuclease SMU1763 from Streptococcus mutans

    Lemak, S., Serbanescu, M. A., Khusnutdinova, A. N., Ruszkowski, M., Beloglazova, N., Xu, X., Brown, G., Cui, H., Tan, K., Joachimiak, A., Cvitkovitch, D. G., Savchenko, A. & Yakunin, A., Nov 2021, In: Journal of Biological Chemistry. 297, 5, 101251.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases

    Khusnutdinova, A. N., Batyrova, K., Brown, G., Fedorchuck, T., Chai, Y. S., Skarina, T., Flick, R., Petit, A-P., Savchenko, A., Stogios, P. & Yakunin, A., Oct 2023, In: Febs Journal. 290, 20, p. 4966-4983 18 p.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Structure and activity of the cold-active and anion-activated carboxyl esterase OLEI01171 from the oil-degrading marine bacterium Oleispira antarctica

    Lemak, S., Tchigvintsev, A., Petit, P., Flick, R., Singer, A. U., Brown, G., Evdokimova, E., Egorova, O., Gonzalez, C. F., Chernikova, T. N., Yakimov, M. M., Kube, M., Reinhardt, R., Golyshin, P. N., Savchenko, A. & Yakunin, A. F., 15 Jul 2012, In: Biochemical Journal. 445, 2, p. 193-203

    Research output: Contribution to journalArticlepeer-review

  11. The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity

    Lemak, S., Nocek, B., Beloglazova, N., Skarina, T., Flick, R., Brown, G., Joachimiak, A., Savchenko, A. & Yakunin, A. F., 29 Sept 2014, In: Nucleic Acids Research. 42, 17, p. 11144-11155

    Research output: Contribution to journalArticlepeer-review