Research Portal

Professor Dyfrig Hughes

Athro mewn Ffarmacoeconomeg / Cyfarwyddwr Ymchwil

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ORCID: 0000-0001-8247-7459
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  1. Published

    Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

    Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

    Research output: Contribution to conference › Paper

  2. Published

    Cost-effectiveness considerations in pharmacogenetics.

    Hughes, D. & Hughes, D. A., 1 Jan 2008.

    Research output: Contribution to conference › Paper

  3. Published

    Cost-effectiveness of HLA-B*15:02 screening in Malaysia

    Plumpton, C. & Hughes, D., Oct 2017, In: British Journal of Dermatology. 177, 4, p. 904-905

    Research output: Contribution to journal › Comment/debate

  4. Published

    Cost-effectiveness of biological therapy for Crohn's disease: Markov cohort analyses incorporating United Kingdom patient-level cost data.

    Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Aug 2009, In: Alimentary Pharmacology and Therapeutics. 30, 3, p. 265-274

    Research output: Contribution to journal › Article › peer-review

  5. Published

    Cost-effectiveness of home versus hospital management of children at onset of Type 1 Diabetes: The DECIDE randomised controlled trial

    McCarroll, Z., Townson, J., Pickles, T., Gregory, J. W., Playle, R., Robling, M. & Hughes, D., 19 May 2021, In: BMJ Open. 11, 5, e043523.

    Research output: Contribution to journal › Article › peer-review

  6. Published

    Cost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial

    Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Sept 2017, In: Frontiers in Pharmacology. 8, 644.

    Research output: Contribution to journal › Article › peer-review

  7. Published

    Cost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework

    Plumpton, C., Pirmohamed, M. & Hughes, D., Jun 2019, In: Clinical Pharmacology and Therapeutics. 105, 6, p. 1429-1438

    Research output: Contribution to journal › Article › peer-review

  8. Published

    Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden

    Verhoef, T. I., Redekop, W. K., Langenskiold, S., Kamali, F., Wadelius, M., Burnside, G., Maitland-van der Zee, A. H., Hughes, D. & Pirmohamed, M., Oct 2016, In: The Pharmacogenomics Journal. 16, p. 478–484

    Research output: Contribution to journal › Article › peer-review

  9. Published

    Cost-effectiveness of screening for HLA-A*31:01 prior to initiation of carbamazepine in epilepsy

    Plumpton, C., Yip, V. L. M., Alfirevic, A., Marson, A. G., Pirmohamed, M. & Hughes, D., Apr 2015, In: Epilepsia.

    Research output: Contribution to journal › Article › peer-review

  10. Published

    Cost-utility analysis of on demand rabeprazole and esomeprazole for symptomatic gastro oesophageal reflux disease

    Hughes, D., Hughes, D. A. & Dubois, D., 1 Nov 2003, In: Value in Health. 6, 6, p. 613

    Research output: Contribution to journal › Article › peer-review

  11. Published

    Cost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease

    Hughes, D. & Hughes, D. A., 1 Nov 2003.

    Research output: Contribution to conference › Paper

  12. Published

    Cost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease

    Hughes, D. & Hughes, D. A., 1 Nov 2003.

    Research output: Contribution to conference › Paper

  13. Published

    Costs of Medication Nonadherence in Patients with Diabetes Mellitus: A Systematic Review and Critical Analysis of the Literature.

    Hughes, D., Salas, M., Hughes, D. A., Zuluaga, A., Vardeva, K. & Lebmeier, M., 1 Sept 2009, In: Value in Health. 12, 6, p. 915-922

    Research output: Contribution to journal › Article › peer-review

  14. Published

    Costs of non-compliance to antipsychotic medications among patients with schizophrenia.

    Hughes, D., Hughes, D. A., Salas, M., Zuluaga, A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 May 2008.

    Research output: Contribution to conference › Paper

  15. Published

    Costs of orphan medicinal products: longitudinal analysis of expenditure in Wales

    Pijeira Perez, Y., Wood, E. & Hughes, D., 1 Nov 2023, In: Orphanet Journal of Rare Diseases. 18, 1, 342.

    Research output: Contribution to journal › Article › peer-review

  16. Published

    Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

    Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417

    Research output: Contribution to journal › Article › peer-review

  17. Published

    Current assessment of risk-benefit by regulators: Is it time to introduce decision analyses?

    Hughes, D., Hughes, D. A., Pirmohamed, M. & Bayoumi, A., 1 Aug 2007.

    Research output: Contribution to conference › Paper

  18. Published

    Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

    Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Aug 2007, In: Clinical Pharmacology and Therapeutics. 82, 2, p. 123-127

    Research output: Contribution to journal › Article › peer-review

  19. Published

    Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses

    Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., [. V., 31 Oct 2011, In: British Medical Journal. 343, p. 1-14

    Research output: Contribution to journal › Article › peer-review

  20. Published

    Decision analytic modelling methods for the assessing the effectiveness of treatment sequences for clinical and economic decision making: a methodological review

    Lewis, R., Hughes, D. & Wilkinson, C., 30 Nov 2017, In: Value in Health. 20, 9, p. A748 1 p.

    Research output: Contribution to journal › Article › peer-review

  21. Published

    Decision-Makers’ Preferences for Approving New Medicines in Wales: A Discrete-Choice Experiment with Assessment of External Validity

    Hughes, D., Linley, W. G. & Hughes, D. A., 1 Apr 2013, In: Pharmacoeconomics. 31, 4, p. 345-355

    Research output: Contribution to journal › Article › peer-review

  22. Published

    Defining rewardable innovation in drug therapy

    Hughes, D., Aronson, J. K., Ferner, R. E. & Hughes, D. A., 1 Apr 2012, In: Nature Reviews Drug Discovery. 11, p. 253-254

    Research output: Contribution to journal › Article › peer-review

  23. Published

    Developing an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project

    Holmes, E., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Foster, D., Hardman, K., Bell, S., Marson, A., Hughes, D. & Noble, A. J., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 28-37 10 p.

    Research output: Contribution to journal › Article › peer-review

  24. Published

    Developing feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed methods study

    Noble, A. J., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Morris, B., Hughes, D., Marson, T. & Holmes, E., Aug 2024, In: Health Services and Delivery Research (HS&DR). 12, 24

    Research output: Contribution to journal › Article › peer-review

  25. Published

    Developing patient-centred, feasible alternative care for adult emergency department users with epilepsy: Protocol for the mixed-methods observational ‘Collaborate’ project.

    Noble, A. J., Mathieson, A., Ridsdale, L., Holmes, E., Morgan, M., McKinlay, A., Dickson, J., Jackson, M., Hughes, D., Goodacre, S. & Marson, A. G., 2 Nov 2019, In: BMJ Open. 9, 11, e031696.

    Research output: Contribution to journal › Article › peer-review

  26. Published

    Development of a Database of Instruments for Resource-Use Measurement: Purpose, Feasibility, and Design

    DIRUM Team, 1 Jul 2012, In: Value in Health. 15, 5, p. 650-655

    Research output: Contribution to journal › Article › peer-review

  27. Published

    Development of an economic model to evaluate the cost-effectiveness of rival therapies for treating Crohn’s disease.

    Hughes, D., Kikuchi, T., Bodger, K. & Hughes, D. A., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

  28. Published

    Do guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review

    Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Jul 2018, In: Thorax. 73, 7, p. 670-673

    Research output: Contribution to journal › Letter › peer-review

  29. Published

    Does Electronic Monitoring Influence Adherence to Medication? Randomized Controlled Trial of Measurement Reactivity

    Hughes, D., Sutton, S., Kinmonth, A. L., Hardeman, W., Hughes, D. A., Boase, S., Prevost, T., Kellar, I., Graffy, J., Griffin, S. & Farmer, A., 1 Dec 2014, In: Annals of Behavioral Medicine. 48, 3, p. 293-299

    Research output: Contribution to journal › Article › peer-review

  30. Published

    Drug compliance and pharmaceconomics

    Hughes, D. & Hughes, D. A., 1 Dec 2003.

    Research output: Contribution to conference › Paper

  31. Published

    Drug evaluation and pharmocoeconomics.

    Hughes, D., Krska, J., Hughes, D. A., Winfield, A. J. (Editor), Rees, J. A. (Editor) & Smith, I. (Editor), 1 Jan 2009, Pharmaceutical Practice: 4th Edition.. 2009 ed. Churchill Livingstone, p. 185-198

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  32. Published

    Drugs for exceptionally rare diseases: do they deserve special status for funding?

    Hughes, D., Tunnage, B. & Yeo, S. T., 1 Nov 2005, In: QJM - An International Journal of Medicine. 98, 11, p. 829-836

    Research output: Contribution to journal › Article › peer-review

  33. Published

    ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

    De Geest, S., Zullig, L. L., Dunbar-Jacob, J., Helmy, R., Hughes, D., Wilson, I. & Vrijens, B., 3 Jul 2018, In: Annals of Internal Medicine. 169, 1, p. 30-35

    Research output: Contribution to journal › Article › peer-review

  34. Published

    Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales

    Gillespie, D., Knapper, C., Hughes, D., Couzen, Z., Wood, F., de Bruin, M., Ma, R., Jones, A. T., Williams, A. & Hood, K., 17 Feb 2021, In: Sexually transmitted infections. 97, 2, p. 85-87 3 p., 054598.

    Research output: Contribution to journal › Article › peer-review

  35. Published

    Economic Studies in Motor Neurone Disease: A Systematic Methodological Review

    Moore, A., Young, C. A. & Hughes, D., Apr 2017, In: Pharmacoeconomics. 35, 4, p. 397-413

    Research output: Contribution to journal › Article › peer-review

  36. Published

    Economic analysis of on-demand maintenance therapy with proton pump inhibitors in patients with non-erosive reflux disease.

    Hughes, D., Hughes, D. A., Bodger, K., Bytzer, P., De Herdt, D. & Dubois, D., 1 Jan 2005, In: Pharmacoeconomics. 23, 10, p. 1031-1041

    Research output: Contribution to journal › Article › peer-review

  37. Published

    Economic analysis of treatments for children who do not achieve adequate asthma control when using low-dose inhaled corticosteroids

    Culeddu, G., Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Turner, S., Smith, C. T. & Hughes, D., 30 Jul 2024, In: Disease in Childhood. 109, suppl 1

    Research output: Contribution to journal › Conference article › peer-review

  38. Published

    Economic considerations for market access of new health technologies: A case study of pharmacogenetic testing

    Hughes, D. & Hughes, D. A., 1 Feb 2008.

    Research output: Contribution to conference › Paper

  39. Published

    Economic considerations for pharmacogenetic testing

    Hughes, D. & Hughes, D. A., 1 Jun 2008.

    Research output: Contribution to conference › Paper

  40. Published

    Economic evaluation during early (phase II) trials

    Hughes, D. & Hughes, D. A., 1 Nov 2002.

    Research output: Contribution to conference › Paper

  41. Published

    Economic evaluation of a behavior-modifying intervention to enhance antiepileptic drug adherence

    Hughes, D., Plumpton, C. O., Brown, I., Reuber, M., Marson, A. G. & Hughes, D. A., 26 Mar 2015, In: Epilepsy and Behavior. 45, p. 180-186

    Research output: Contribution to journal › Article › peer-review

  42. Published

    Economic evaluation of infliximab and adalimumab for Crohn's disease.

    Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Jan 2009.

    Research output: Contribution to conference › Paper

  43. Published
  44. Published

    Economic evaluation of steroid injections (methylprednisolone) in the treatment of Morton's neuroma: patient-blind randomised trial

    Hughes, D., Thomson, C., Beggs, I., Martin, D., McCaldin, D., Russell, D., Edwards, R. T., Hughes, D. A., Yeo, S. T., Russell, I. T. & Gibson, T. N., 1 Mar 2007.

    Research output: Contribution to conference › Paper

  45. Published

    Economic evaluations during early (Phase II) drug development: A role for clinical trial simulations.

    Hughes, D., Hughes, D. A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 11, p. 1069-1077

    Research output: Contribution to journal › Article › peer-review

  46. Published

    Economic impact of poor compliance with pharmaceuticals.

    Hughes, D. & Hughes, D. A., 1 Aug 2002, In: Expert Review of Pharmacoeconomics and Outcomes Research. 2, 4, p. 327-335

    Research output: Contribution to journal › Article › peer-review

  47. Published

    Economics of pharmacogenetic guided treatments: Underwhelming or overstated?

    Hughes, D., May 2018, In: Clinical Pharmacology and Therapeutics. 103, 5, p. 749-751

    Research output: Contribution to journal › Article › peer-review

  48. Published

    Effectiveness of out-patient based acute heart failure care: A pilot randomised controlled trial

    Wong, K. Y. K., Hughes, D., Debski, M., Latt, N., Assaf, O., Abdelrahman, A., Taylor, R., Allgar, V., McNeill, L., Howard, S., Wong, S. Y. S., Jones, R., Cassidy, C. J., Seed, A., Galasko, G., Clark, A., Davis, G. K., Montasem, A., Lang, C. C., Kalra, P. R., Campbell, R., Lip, G. Y. H. & Cleland, J. G. F., Oct 2023, In: Acta Cardiologica. 78, 7, p. 828-837 10 p.

    Research output: Contribution to journal › Article › peer-review

  49. Published

    Effects of the abolition of prescription charges in Wales: A preliminary analysis

    Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

    Research output: Contribution to conference › Paper

  50. Published

    Effects of the abolition of prescription charges in Wales: a preliminary analysis.

    Hughes, D., Cohen, D., Alam, M. F., Hughes, D. A., Dunstan, F. & Routledge, P., 1 Jan 2008, In: International Journal of Pharmacy Practice. 16, Supplement 1, p. A39

    Research output: Contribution to journal › Article › peer-review

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