Professor Dyfrig Hughes
Athro mewn Ffarmacoeconomeg / Cyfarwyddwr Ymchwil
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Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Jul 2005.Research output: Contribution to conference › Paper
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Psychometric properties of an adapted stigma scale and experiences of stigma associated with HIV pre-exposure prophylaxis use among men who have sex with men: a mixed methods study
Gillespie, D. & Hughes, D., Jul 2023, In: AIDS and Behavior. 27, 7, p. 2397-2410 14 p.Research output: Contribution to journal › Article › peer-review
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Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study
Hughes, D. & Poletti-Hughes, J., 21 Oct 2016, In: PLoS ONE. 11, 10, e0164681.Research output: Contribution to journal › Article › peer-review
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Prescription fee exemption research study
Hughes, D., Myles, S., Hughes, D. A., Routledge, P. & Wales, D. F., 1 Jun 2006.Research output: Contribution to conference › Paper
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Predictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey
Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Mar 2015, In: Value in Health. 18, 2, p. 206-216Research output: Contribution to journal › Article › peer-review
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Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research
Holmes, E. A., Morrison, V. L. & Hughes, D., 8 Dec 2014, In: Value in Health. 17, 8, p. 863-876Research output: Contribution to journal › Article › peer-review
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Predicting "real world" effectiveness by integrating adherence with pharmacodynamic modelling.
Hughes, D., Hughes, D. A. & Walley, T., 1 Jul 2003, In: Clinical Pharmacology and Therapeutics. 74, 1, p. 1-8Research output: Contribution to journal › Article › peer-review
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Pragmatic trials - design features and implications for clinical decision making
Hughes, D., Urdahl, H., Hughes, D. A. & Freemantle, N., 1 Aug 2000.Research output: Contribution to conference › Paper
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PrEP use, sexual behaviour, and PrEP adherence among men who have sex with men living in Wales prior to and during the COVID-19 pandemic
Gillespie, D., Couzens, Z., de Bruin, M., Hughes, D., Jones, A., Ma, R., Williams, A., Wood, F. & Blee, K., Aug 2022, In: AIDS and Behavior. 26, 8, p. 2746-2757 12 p.Research output: Contribution to journal › Article › peer-review
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Population pharmacokinetics of warfarin: Intermin analysis of the Liverpool pharmacogenetic prospective cohort study
Hughes, D., Matthews, I., Aarons, L., Al-Zubiedi, S., Hatch, E., Lane, S., Williamson, P., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Nov 2007.Research output: Contribution to conference › Paper
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Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone.
Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, G., Watkins, W. A. & Ward, S., 1 Mar 2006, In: British Journal of Clinical Pharmacology. 61, 3, p. 289-300Research output: Contribution to journal › Article › peer-review
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Policy on ultra-orphan drugs.
Hughes, D. & Hughes, D. A., 1 Jan 2007, 2007 ed. Unknown.Research output: Book/Report › Commissioned report
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Plasma Methylmalonic Acid Concentration in Folic Acid–Supplemented Depressed Patients with Low or Marginal Vitamin B-12: A Randomized Trial
Carter, B., Zenasni, Z., Moat, S. J., Hudson, P. R., Russell, I. T., McCaddon, A., Whitaker, R., Pink, J., Roberts, S., Wilkinson, C., Hughes, D., Betson, E., Carr, D., Jorgenson, A., Pirmohamed, M., Williams, N., Lewis, H., Lloyd, K., Sylvesture, Y. & Tranter, R., Dec 2021, In: Journal of Nutrition. 151, 12, p. 3738-3745 8 p.Research output: Contribution to journal › Article › peer-review
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Physchiatrist prescribing preferences and attitudes toward promotion
Hughes, D., Menkes, D., Davies, R. & Hughes, D. A., 1 Apr 2006.Research output: Contribution to conference › Paper
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Pharmacometric analysis of duration of drug action: implications for improved forgiveness to medication non-compliance
Hughes, D., Hughes, D. A. & Walley, T., 1 Sept 2001.Research output: Contribution to conference › Paper
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Pharmacokinetics, patient compliance and pharmaeconomics
Hughes, D. & Hughes, D. A., 1 Jun 2005.Research output: Contribution to conference › Paper
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Pharmacokinetic-Pharmacodynamic modelling of Lapdap (CPG-DDS) combination.
Hughes, D., Hughes, D. A., Watkins, B. & Winstanley, P., 1 Jan 2001, 2001 ed. Unknown.Research output: Book/Report › Commissioned report
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Pharmacogenomics spotlight commentary: From the United Kingdom to global populations
Magavern, E. F., Daly, A. K., Gilchrist, A. & Hughes, D., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4546-4548 3 p., 14917.Research output: Contribution to journal › Comment/debate › peer-review
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Pharmacogenetic tests: the need for a level playing field
Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4Research output: Contribution to journal › Article › peer-review
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Pharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery
Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Jul 2015, In: British Journal of Clinical Pharmacology. 80, 5, p. 1149-1159Research output: Contribution to journal › Article › peer-review
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Pharmacoeconomics: principles and relevance to the activities of drug and therapeutics committees.
Hughes, D., Hughes, D. A. & Reynolds, D. J., 1 Oct 2009, In: Clinical Medicine. 9, 5, p. 490-492Research output: Contribution to journal › Article › peer-review
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Pharmacoeconomics of pharmacogenetic testing: azathioprine
Hughes, D., McAllister, R. & Hughes, D. A., 1 Apr 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomics in Wales: functions of the all Wales medicines strategy group
Hughes, D. & Hughes, D. A., 1 Apr 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomics appraisals by the all Wales medicines strategy group
Hughes, D. & Hughes, D. A., 1 Jul 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomic models that incorporate non-compliance
Hughes, D. & Hughes, D. A., 1 Jul 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomic evaluations in Ireland, Scotland and Wales: A Celtic perspective on pharmaceutical assessment
Hughes, D., Hughes, D. A., Drummond, M., Tolley, K. & Ryan, M., 1 Oct 2007.Research output: Contribution to conference › Paper
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Pharmaceutical Technologies Conditionally Approved By The National Institute For Health And Care Excellence: A Critical Analysis
Pijeira Perez, Y. & Hughes, D., 7 Jan 2025, OP41 Pharmaceutical Technologies Conditionally Approved By The National Institute For Health And Care Excellence: A Critical Analysis.: Abstracts from the HTAi 2024 Meeting in Seville, Spain . Special Issue S1 ed. International Journal of Technology Assessment in Health Care., Vol. 40.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Perceptions of European ME/CFS experts concerning knowledge and understanding of ME/CFS among primary care physicians in Europe: A report from the European ME/CFS Research Network (EUROMENE)
Cullinan, J., Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., de Korwin, J.-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 26 Feb 2021, In: Medicina. 57, 3, 208.Research output: Contribution to journal › Article › peer-review
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Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A590Research output: Contribution to journal › Article › peer-review
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Patients' and healthcare professionals' views of cancer follow-up: systematic review
Lewis, R., Neal, R. D., Hendry, M., France, B., Williams, N. H., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., Jul 2009, In: British Journal of General Practice. 59, 564, p. e248-e259Research output: Contribution to journal › Article › peer-review
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Patient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations
Ridyard, C. & Hughes, D., 7 May 2017, p. P141. 1 p.Research output: Contribution to conference › Poster › peer-review
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Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study
Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L., Jul 2024, In: ACR Open Rheumatology. 6, 7, p. 403-411 9 p.Research output: Contribution to journal › Article › peer-review
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Patient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs
Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Mar 2019, In: Clinical Pharmacology and Therapeutics. 105, 3, p. 672-683 12 p.Research output: Contribution to journal › Article › peer-review
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Patient preferences for outcomes in clinical trials: implications for medicines optimization
Holmes, E., Marson, A. G. & Hughes, D., 8 May 2017, In: Trials. 18 (Suppl 1), O18, p. 192 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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Patient compliance and pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Oct 2001.Research output: Contribution to conference › Paper
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Patient compliance and pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Nov 2002.Research output: Contribution to conference › Paper
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Patient compliance and persistence with prescribed medication: Measurement and health economic impact
Hughes, D., Koncz, T., Hughes, D. A., Cleemput, I. & Annemans, L., 1 May 2004.Research output: Contribution to conference › Paper
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Parenting programme for parents of children at risk of developing conduct disorder: cost effectiveness analysis.
Bywater, T. J., Hutchings, J. M., Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 31 Mar 2007, In: British Medical Journal. 334, 7595, p. 682-685Research output: Contribution to journal › Article › peer-review
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Orphan drugs revisited: author's response.
Hughes, D. & Hughes, D. A., 1 May 2006, In: Quarterly Journal of Medicine. 99, 5, p. 350-351Research output: Contribution to journal › Article › peer-review
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Orphan drug treatments: economic considerations
Hughes, D. & Hughes, D. A., 1 Nov 2007.Research output: Contribution to conference › Paper
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Opportunity costs and local health service spending decisions: a qualitative study from Wales
Schaffer, S. K., Sussex, J., Hughes, D. & Devlin, N., 25 Mar 2016, In: BMC Health Services Research. 16, 103Research output: Contribution to journal › Article › peer-review
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Nurse-led vs. conventional physician-led follow-up for patients with cancer: systematic review
Lewis, R., Neal, R. D., Williams, N. H., France, B., Wilkinson, C. E., Hendry, M., Russell, D., Russell, I., Hughes, D., Stuart, N. S. & Weller, D., 1 Apr 2009, In: Journal of Advanced Nursing. 65, 4, p. 706-723Research output: Contribution to journal › Article › peer-review
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Novel oral iron therapy for iron deficiency anaemia: How to value safety in a new drug?
Culeddu, G., Su, L., Chen, Y., Pereira, D. I. A., Powell, J. J. & Hughes, D., Mar 2022, In: British Journal of Clinical Pharmacology. 88, 3, p. 1347-1357 11 p.Research output: Contribution to journal › Article › peer-review
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Non-compliance with antibiotic therapy for acute community infections: A global survey.
Hughes, D., Pechere, J. C., Hughes, D. A., Kardas, P. & Cornaglia, G., 1 Mar 2007, In: International Journal of Antimicrobial Agents. 29, 3, p. 245-253Research output: Contribution to journal › Article › peer-review
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New drugs for old: disinvestment and NICE.
Hughes, D., Hughes, D. A. & Ferner, R. E., 25 Feb 2010, In: British Medical Journal. 340, p. c572Research output: Contribution to journal › Article › peer-review
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New advice on switching antiepileptic drugs might be a false economy
Holmes, E. A., Plumpton, C. O., Hughes, D., Holmes, E., Plumpton, C., Duerden, M., Marson, T. & Hughes, D. A., 16 Dec 2013, In: British Medical Journal. 347Research output: Contribution to journal › Article › peer-review
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New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes
Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., May 2018, In: Pharmacoeconomics. 36, 5, p. 613-624 12 p.Research output: Contribution to journal › Article › peer-review
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NICE recommendations: why no disinvestment recommendations to offset investment decisions?
Hughes, D., Tuersley, L. V., Hughes, D. A., Wood, E. M. & Tuersley, L., 19 May 2015, In: BMJ. 350Research output: Contribution to journal › Article › peer-review
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NICE and new: appraising innovation.
Hughes, D., Ferner, R. E., Hughes, D. A. & Aronson, J. K., 5 Jan 2010, In: British Medical Journal. 340, p. b5493Research output: Contribution to journal › Article › peer-review
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Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial
Brogan, P. A., Arch, B., Hickey, H., Anton, J., Iglesias, E., Baildam, E., Mahmood, K., Cleary, G., Moraitis, E., Papadopoulou, C., Beresford, M. W., Riley, P., Demir, S., Ozen, S., Culeddu, G., Hughes, D., Dolezalova, P., Hampson, L., Whitehead, J., Jayne, D., Ruperto, N., Tudor-Smith, C. & Eleftheriou, D., Sept 2021, In: Arthritis and Rheumatology. 73, 9, p. 1673-1682Research output: Contribution to journal › Article › peer-review