Research Portal

Dr Geoff Coombs

Lecturer in Sport & Exercise Science

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  1. Article › Research › Not peer-reviewed

  2. Isolating the independent influence of body fat on thermoregulatory responses to exercise

    Coombs, G. B., Stamatakis, E. & Jay, O., Jul 2015, In: European Journal of Applied Physiology. 115, 7, p. 1601-2 2 p.

    Research output: Contribution to journal › Article

  3. Article › Research › Peer-reviewed

  4. A comparison of thermoregulatory responses to exercise between mass-matched groups with large differences in body fat

    Dervis, S., Coombs, G. B., Chaseling, G. K., Filingeri, D., Smoljanic, J. & Jay, O., 15 Mar 2016, In: Journal of applied physiology (Bethesda, Md. : 1985). 120, 6, p. 615-23 9 p.

    Research output: Contribution to journal › Article › peer-review

  5. Acute acetaminophen ingestion does not alter core temperature or sweating during exercise in hot-humid conditions

    Coombs, G. B., Cramer, M. N., Ravanelli, N. M., Morris, N. B. & Jay, O., Jun 2015, In: Scandinavian Journal of Medicine and Science in Sports. 25 Suppl 1, p. 96-103 8 p.

    Research output: Contribution to journal › Article › peer-review

  6. Acute effect of Finnish sauna bathing on brachial artery flow-mediated dilation and reactive hyperemia in healthy middle-aged and older adults

    Gravel, H., Coombs, G. B., Behzadi, P., Marcoux-Clément, V., Barry, H., Juneau, M., Nigam, A. & Gagnon, D., Jul 2019, In: Physiological Reports. 7, 13, p. e14166

    Research output: Contribution to journal › Article › peer-review

  7. Acute heat stress reduces biomarkers of endothelial activation but not macro- or microvascular dysfunction in cervical spinal cord injury

    Coombs, G. B., Barak, O. F., Phillips, A. A., Mijacika, T., Sarafis, Z. K., Lee, A. H. X., Squair, J. W., Bammert, T. D., DeSouza, N. M., Gagnon, D., Krassioukov, A. V., Dujic, Z., DeSouza, C. A. & Ainslie, P. N., 1 Mar 2019, In: American Journal of Physiology - Heart and Circulatory Physiology. 316, 3, p. H722-H733

    Research output: Contribution to journal › Article › peer-review

  8. Acute isometric and dynamic exercise do not alter cerebral sympathetic nerve activity in healthy humans

    Tymko, M. M., Drapeau, A., Vieira-Coelho, M. A., Labrecque, L., Imhoff, S., Coombs, G. B., Langevin, S., Fortin, M., Châteauvert, N., Ainslie, P. N. & Brassard, P., 13 Apr 2024, (E-pub ahead of print) In: Journal of Cerebral Blood Flow and Metabolism. 12 p.

    Research output: Contribution to journal › Article › peer-review

  9. Acute reductions in haematocrit increase flow-mediated dilatation independent of resting nitric oxide bioavailability in humans

    Hoiland, R. L., Tremblay, J. C., Stacey, B. S., Coombs, G. B., Nowak-Flück, D., Tymko, M. M., Patrician, A., Stembridge, M., Howe, C. A., Bailey, D. M., Green, D. J., MacLeod, D. B. & Ainslie, P. N., Oct 2020, In: Journal of Physiology. 598, 19, p. 4225-4236 12 p.

    Research output: Contribution to journal › Article › peer-review

  10. Age- and sex-related differences in sympathetic vascular transduction and neurohemodynamic balance in humans

    D'Souza, A. W., Hissen, S. L., Manabe, K., Takeda, R., Washio, T., Coombs, G. B., Sanchez, B., Fu, Q. & Shoemaker, J. K., 1 Oct 2023, In: American Journal of Physiology - Heart and Circulatory Physiology. 325, 4, p. H917-H932

    Research output: Contribution to journal › Article › peer-review

  11. Alarming blood pressure changes during routine bladder emptying in a woman with cervical spinal cord injury

    Lee, A. H. X., Phillips, A. A., Squair, J. W., Barak, O. F., Coombs, G. B., Ainslie, P. N., Sarafis, Z. K., Mijacika, T., Vucina, D., Dujic, Z. & Krassioukov, A. V., 28 Dec 2017, In: Spinal cord series and cases. 3, 17101.

    Research output: Contribution to journal › Article › peer-review

  12. Cerebral O2 and CO2 transport in isovolumic haemodilution: Compensation of cerebral delivery of O2 and maintenance of cerebrovascular reactivity to CO2

    Carr, J. M., Ainslie, P. N., MacLeod, D. B., Tremblay, J. C., Nowak-Flück, D., Howe, C. A., Stembridge, M., Patrician, A., Coombs, G. B., Stacey, B. S., Bailey, D. M., Green, D. J. & Hoiland, R. L., Jan 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 1, p. 99-114 16 p.

    Research output: Contribution to journal › Article › peer-review

  13. Cerebrovascular function is preserved during mild hyperthermia in cervical spinal cord injury

    Coombs, G. B., Vucina, D., Caldwell, H. G., Barak, O. F., Mijacika, T., Lee, A. H. X., Sarafis, Z. K., Squair, J. W., Krassioukov, A. V., Phillips, A. A., Dujic, Z. & Ainslie, P. N., Nov 2019, In: Spinal cord. 57, 11, p. 979-984 6 p.

    Research output: Contribution to journal › Article › peer-review

  14. Common carotid artery responses to the cold-pressor test are impaired in individuals with cervical spinal cord injury

    Sarafis, Z. K., Squair, J. W., Barak, O. F., Coombs, G. B., Soriano, J. E., Larkin-Kaiser, K. A., Lee, A. H. X., Hansen, A., Vodopic, M., Romac, R., Grant, C., Charbonneau, R., Mijacika, T., Krassioukov, A. V., Ainslie, P. N., Dujic, Z. & Phillips, A. A., 1 Dec 2022, In: American Journal of Physiology - Heart and Circulatory Physiology. 323, 6, p. H1311-H1322

    Research output: Contribution to journal › Article › peer-review

  15. Differential Expression of Vascular-Related MicroRNA in Circulating Endothelial Microvesicles in Adults With Spinal Cord Injury: A Pilot Study

    Park, A. J., Fandl, H. K., Garcia, V. P., Coombs, G. B., DeSouza, N. M., Greiner, J. J., Barak, O. F., Mijacika, T., Dujic, Z., Ainslie, P. N. & DeSouza, C. A., 3 Apr 2023, In: Topics in spinal cord injury rehabilitation. 29, 2, p. 34-42 9 p.

    Research output: Contribution to journal › Article › peer-review

  16. Distinct contributions of skin and core temperatures to flow-mediated dilation of the brachial artery following passive heating

    Coombs, G. B., Tremblay, J. C., Shkredova, D. A., Carr, J. M. J. R., Wakeham, D. J., Patrician, A. & Ainslie, P. N., 1 Jan 2021, In: Journal of applied physiology (Bethesda, Md. : 1985). 130, 1, p. 149-159 11 p.

    Research output: Contribution to journal › Article › peer-review

  17. Effects of circulating extracellular microvesicles from spinal cord-injured adults on endothelial cell function

    Brewster, L. M., Coombs, G. B., Garcia, V. P., Hijmans, J. G., DeSouza, N. M., Stockelman, K. A., Barak, O. F., Mijacika, T., Dujic, Z., Greiner, J. J., Phillips, A. A., Ainslie, P. N. & DeSouza, C. A., 17 Apr 2020, In: Clinical science (London, England : 1979). 134, 7, p. 777-789 13 p.

    Research output: Contribution to journal › Article › peer-review

  18. Evidence for temperature-mediated regional increases in cerebral blood flow during exercise

    Caldwell, H. G., Coombs, G. B., Howe, C. A., Hoiland, R. L., Patrician, A., Lucas, S. J. E. & Ainslie, P. N., Apr 2020, In: Journal of Physiology. 598, 8, p. 1459-1473 15 p.

    Research output: Contribution to journal › Article › peer-review

  19. Global REACH 2018: The Effect of an Expiratory Resistance Mask with Dead Space on Sleep and Acute Mountain Sickness During Acute Exposure to Hypobaric Hypoxia

    Carr, J., Stone, R., Tymko, C., Tymko, K., Coombs, G. B., Hoiland, R. L., Howe, C. A., Tymko, M. M., Ainslie, P. N. & Patrician, A., Sept 2020, In: High Altitude Medicine and Biology. 21, 3, p. 297-302 6 p.

    Research output: Contribution to journal › Article › peer-review

  20. Global REACH 2018: The influence of acute and chronic hypoxia on cerebral haemodynamics and related functional outcomes during cold and heat stress

    Gibbons, T. D., Tymko, M. M., Thomas, K. N., Wilson, L. C., Stembridge, M., Caldwell, H. G., Howe, C. A., Hoiland, R. L., Akerman, A. P., Dawkins, T. G., Patrician, A., Coombs, G. B., Gasho, C., Stacey, B. S., Ainslie, P. N. & Cotter, J. D., Jan 2020, In: Journal of Physiology. 598, 2, p. 265-284 20 p.

    Research output: Contribution to journal › Article › peer-review

  21. Global REACH 2018: High Blood Viscosity and Hemoglobin Concentration Contribute to Reduced Flow-Mediated Dilation in High-Altitude Excessive Erythrocytosis

    Tremblay, J. C., Hoiland, R. L., Howe, C. A., Coombs, G. B., Vizcardo-Galindo, G. A., Figueroa-Mujíca, R. J., Bermudez, D., Gibbons, T. D., Stacey, B. S., Bailey, D. M., Tymko, M. M., MacLeod, D. B., Gasho, C., Villafuerte, F. C., Pyke, K. E. & Ainslie, P. N., Jun 2019, In: Hypertension (Dallas, Tex. : 1979). 73, 6, p. 1327-1335 9 p.

    Research output: Contribution to journal › Article › peer-review

  22. Global Reach 2018: Nitric oxide-mediated cutaneous vasodilation is reduced in chronic, but not acute, hypoxia independently of enzymatic superoxide formation

    Coombs, G. B., Akins, J. D., Patik, J. C., Vizcardo-Galindo, G. A., Figueroa-Mujica, R., Tymko, M. M., Stacey, B. S., Iannetelli, A., Bailey, D. M., Villafuerte, F. C., Ainslie, P. N. & Brothers, R. M., 20 Aug 2021, In: Free radical biology & medicine. 172, p. 451-458 8 p.

    Research output: Contribution to journal › Article › peer-review

  23. Global Reach 2018: reduced flow-mediated dilation stimulated by sustained increases in shear stress in high-altitude excessive erythrocytosis

    Tremblay, J. C., Coombs, G. B., Howe, C. A., Vizcardo-Galindo, G. A., Figueroa-Mujíca, R. J., Bermudez, D., Tymko, M. M., Villafuerte, F. C., Ainslie, P. N. & Pyke, K. E., 1 Nov 2019, In: American Journal of Physiology - Heart and Circulatory Physiology. 317, 5, p. H991-H1001

    Research output: Contribution to journal › Article › peer-review

  24. Global Research Expedition on Altitude-related Chronic Health 2018 Iron Infusion at High Altitude Reduces Hypoxic Pulmonary Vasoconstriction Equally in Both Lowlanders and Healthy Andean Highlanders

    Patrician, A., Dawkins, T., Coombs, G. B., Stacey, B., Gasho, C., Gibbons, T., Howe, C. A., Tremblay, J. C., Stone, R., Tymko, K., Tymko, C., Akins, J. D., Hoiland, R. L., Vizcardo-Galindo, G. A., Figueroa-Mujíca, R., Villafuerte, F. C., Bailey, D. M., Stembridge, M., Anholm, J. D., Tymko, M. M. & Ainslie, P. N., Apr 2022, In: Chest. 161, 4, p. 1022-1035 14 p.

    Research output: Contribution to journal › Article › peer-review

  25. Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent and S-nitrosothiol mediated signal transduction

    Hoiland, R. L., MacLeod, D. B., Stacey, B. S., Caldwell, H. G., Howe, C. A., Nowak-Flück, D., Carr, J. M., Tymko, M. M., Coombs, G. B., Patrician, A., Tremblay, J. C., Van Mierlo, M., Gasho, C., Stembridge, M., Sekhon, M. S., Bailey, D. M. & Ainslie, P. N., Sept 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 9, p. 1519-1531 13 p.

    Research output: Contribution to journal › Article › peer-review

  26. Hourly staircase sprinting exercise "snacks" improve femoral artery shear patterns but not flow-mediated dilation or cerebrovascular regulation: a pilot study

    Caldwell, H. G., Coombs, G. B., Rafiei, H., Ainslie, P. N. & Little, J. P., May 2021, In: Applied Physiology, Nutrition, and Metabolism. 46, 5, p. 521-529 9 p.

    Research output: Contribution to journal › Article › peer-review

  27. Ice Slurry Ingestion Leads to a Lower Net Heat Loss during Exercise in the Heat

    Morris, N. B., Coombs, G. & Jay, O., Jan 2016, In: Medicine and Science in Sports and Exercise. 48, 1, p. 114-22 9 p.

    Research output: Contribution to journal › Article › peer-review

  28. Impact of ischemic heart disease and cardiac rehabilitation on cerebrovascular compliance

    Coombs, G. B., Al-Khazraji, B. K., Suskin, N. & Shoemaker, J. K., 1 Oct 2023, In: Journal of applied physiology (Bethesda, Md. : 1985). 135, 4, p. 753-762 10 p.

    Research output: Contribution to journal › Article › peer-review

  29. Internal carotid and brachial artery shear-dependent vasodilator function in young healthy humans

    Carr, J. M. J. R., Hoiland, R. L., Caldwell, H. G., Coombs, G. B., Howe, C. A., Tremblay, J. C., Green, D. J. & Ainslie, P. N., Dec 2020, In: Journal of Physiology. 598, 23, p. 5333-5350 18 p.

    Research output: Contribution to journal › Article › peer-review

  30. Maximum Skin Wettedness after Aerobic Training with and without Heat Acclimation

    Ravanelli, N., Coombs, G. B., Imbeault, P. & Jay, O., Feb 2018, In: Medicine and Science in Sports and Exercise. 50, 2, p. 299-307 9 p.

    Research output: Contribution to journal › Article › peer-review

  31. Normobaric hypoxia does not alter the critical environmental limits for thermal balance during exercise-heat stress

    Coombs, G. B., Cramer, M. N., Ravanelli, N., Imbeault, P. & Jay, O., Jan 2021, In: Experimental Physiology. 106, 1, p. 359-369 11 p.

    Research output: Contribution to journal › Article › peer-review

  32. Passive heat therapy for cerebral protection: new ideas of age-old concepts

    Coombs, G. B. & Tremblay, J. C., Jan 2019, In: Journal of Physiology. 597, 2, p. 371-372 2 p.

    Research output: Contribution to journal › Article › peer-review

  33. Passive leg cycling increases activity of the cardiorespiratory system in people with tetraplegia

    Soriano, J. E., Romac, R., Squair, J. W., Barak, O. F., Sarafis, Z. K., Lee, A. H. X., Coombs, G. B., Vaseghi, B., Grant, C., Charbonneau, R., Mijacika, T., Krassioukov, A. V., Ainslie, P. N., Larkin-Kaiser, K. A., Phillips, A. A. & Dujic, Z., 3 Mar 2022, In: Applied Physiology, Nutrition, and Metabolism. 47, 3, p. 269-277 9 p.

    Research output: Contribution to journal › Article › peer-review

  34. Severity-dependent influence of isocapnic hypoxia on reaction time is independent of neurovascular coupling

    Caldwell, H. G., Coombs, G. B., Tymko, M. M., Nowak-Flück, D. & Ainslie, P. N., 1 May 2018, In: Physiology and Behavior. 188, p. 262-269 8 p.

    Research output: Contribution to journal › Article › peer-review

  35. Sleep-disordered breathing is associated with brain vascular reactivity in spinal cord injury

    Squair, J. W., Lee, A. H. X., Sarafis, Z. K., Coombs, G., Barak, O., Cragg, J. J., Mijacika, T., Pecotic, R., Krassioukov, A. V., Dogas, Z., Dujic, Z. & Phillips, A. A., 10 Dec 2019, In: Neurology. 93, 24, p. e2181-e2191

    Research output: Contribution to journal › Article › peer-review

  36. Spinal Cord Disruption Is Associated with a Loss of Cushing-Like Blood Pressure Interactions

    Saleem, S., Sarafis, Z. K., Lee, A. H. X., Squair, J. W., Barak, O. F., Sober-Williams, E., Suraj, R., Coombs, G. B., Mijacika, T., West, C. R., Krassioukov, A. V., Ainslie, P. N., Dujic, Z., Tzeng, Y.-C. & Phillips, A. A., 1 May 2019, In: Journal of Neurotrauma. 36, 9, p. 1487-1490 4 p.

    Research output: Contribution to journal › Article › peer-review

  37. Standing middle cerebral artery velocity predicts cognitive function and gait speed in older adults with cognitive impairment, and is impacted by sex differences

    Fitzgibbon-Collins, L. K., Coombs, G. B., Noguchi, M., Parihar, S., Hughson, R. L., Borrie, M., Peters, S., Shoemaker, J. K. & Bhangu, J., Jan 2024, In: Cerebral circulation - cognition and behavior. 6, p. 100198

    Research output: Contribution to journal › Article › peer-review

  38. Temporal changes in pulmonary gas exchange efficiency when breath-hold diving below residual volume

    Patrician, A., Spajić, B., Gasho, C., Caldwell, H. G., Dawkins, T., Stembridge, M., Lovering, A. T., Coombs, G. B., Howe, C. A., Barak, O., Drviš, I., Dujić, Ž. & Ainslie, P. N., Apr 2021, In: Experimental Physiology. 106, 4, p. 1120-1133 14 p.

    Research output: Contribution to journal › Article › peer-review

  39. Published

    The 2018 Global Research Expedition on Altitude-related Chronic Health (REACH) to Cerro de Pasco, Peru: An Experimental Overview

    Tymko, M. M., Hoiland, R. L., Tremblay, J. C., Stembridge, M., Dawkins, T. G., Coombs, G. B., Patrician, A., Howe, C. A., Gibbons, T. D., Moore, J. P., Simpson, L. L., Steinback, C. D., Meah, V. L., Stacey, B. S., Bailey, D. M., MacLeod, D. B., Gasho, C., Anholm, J. D., Bain, A. R., Lawley, J. S., Villafuerte, F. C., Vizcardo-Galindo, G. & Ainslie, P. N., Jan 2021, In: Experimental Physiology. 106, 1, p. 86-103 18 p.

    Research output: Contribution to journal › Article › peer-review

  40. The Effect of an Expiratory Resistance Mask with Dead Space on Sleep, Acute Mountain Sickness, Cognition, and Ventilatory Acclimatization in Normobaric Hypoxia

    Patrician, A., Tymko, M. M., Caldwell, H. G., Howe, C. A., Coombs, G. B., Stone, R., Hamilton, A., Hoiland, R. L. & Ainslie, P. N., Mar 2019, In: High Altitude Medicine and Biology. 20, 1, p. 61-70 10 p.

    Research output: Contribution to journal › Article › peer-review

  41. The interactive effects of age and sex on the neuro-cardiovascular responses during fatiguing rhythmic handgrip exercise

    D'Souza, A. W., Takeda, R., Manabe, K., Hissen, S. L., Washio, T., Coombs, G. B., Sanchez, B., Fu, Q. & Shoemaker, J. K., 15 Jul 2023, In: Journal of Physiology. 601, 14, p. 2877-2898 22 p.

    Research output: Contribution to journal › Article › peer-review

  42. Thermoregulatory adaptations with progressive heat acclimation are predominantly evident in uncompensable, but not compensable, conditions

    Ravanelli, N., Coombs, G., Imbeault, P. & Jay, O., 1 Oct 2019, In: Journal of applied physiology (Bethesda, Md. : 1985). 127, 4, p. 1095-1106 12 p.

    Research output: Contribution to journal › Article › peer-review

  43. Thermoregulatory responses to exercise at a fixed rate of heat production are not altered by acute hypoxia

    Coombs, G. B., Cramer, M. N., Ravanelli, N., Imbeault, P. & Jay, O., 1 May 2017, In: Journal of applied physiology (Bethesda, Md. : 1985). 122, 5, p. 1198-1207 10 p.

    Research output: Contribution to journal › Article › peer-review

  44. Vascular dysfunction following breath-hold diving

    Barak, O. F., Janjic, N., Drvis, I., Mijacika, T., Mudnic, I., Coombs, G. B., Thom, S. R., Madic, D. & Dujic, Z., Feb 2020, In: Canadian journal of physiology and pharmacology. 98, 2, p. 124-130 7 p.

    Research output: Contribution to journal › Article › peer-review

  45. Wavelet decomposition analysis is a clinically relevant strategy to evaluate cerebrovascular buffering of blood pressure after spinal cord injury

    Saleem, S., Vucina, D., Sarafis, Z., Lee, A. H. X., Squair, J. W., Barak, O. F., Coombs, G. B., Mijacika, T., Krassioukov, A. V., Ainslie, P. N., Dujic, Z., Tzeng, Y.-C. & Phillips, A. A., 1 May 2018, In: American Journal of Physiology - Heart and Circulatory Physiology. 314, 5, p. H1108-H1114

    Research output: Contribution to journal › Article › peer-review

  46. Review article › Research › Peer-reviewed

  47. Highs and lows of hyperoxia: physiological, performance, and clinical aspects

    Brugniaux, J. V., Coombs, G. B., Barak, O. F., Dujic, Z., Sekhon, M. S. & Ainslie, P. N., 1 Jul 2018, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 1, p. R1-R27

    Research output: Contribution to journal › Review article › peer-review

  48. Ventilatory and cerebrovascular regulation and integration at high-altitude

    Hoiland, R. L., Howe, C. A., Coombs, G. B. & Ainslie, P. N., Aug 2018, In: Clinical Autonomic Research . 28, 4, p. 423-435 13 p.

    Research output: Contribution to journal › Review article › peer-review