2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans
Research output: Contribution to journal › Article › peer-review
Electronic versions
DOI
As part of our effort to sequence the 100-megabase (Mb) genome of the nematode Caenorhabditis elegans, we have completed the nucleotide sequence of a contiguous 2,181,032 base pairs in the central gene cluster of chromosome III. Analysis of the finished sequence has indicated an average density of about one gene per five kilobases; comparison with the public sequence databases reveals similarities to previously known genes for about one gene in three. In addition, the genomic sequence contains several intriguing features, including putative gene duplications and a variety of other repeats with potential evolutionary implications.
Keywords
- Animals, Caenorhabditis elegans/genetics, Chromosome Mapping, Databases, Factual, Genes, Helminth, Genes, Homeobox, Molecular Sequence Data, Multigene Family, RNA, Transfer/genetics, Repetitive Sequences, Nucleic Acid, Sequence Analysis, DNA
| Original language | English |
|---|---|
| Pages (from-to) | 32-8 |
| Number of pages | 7 |
| Journal | Nature |
| Volume | 368 |
| Issue number | 6466 |
| DOIs | |
| Publication status | Published - 3 Mar 1994 |