2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans
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In: Nature, Vol. 368, No. 6466, 03.03.1994, p. 32-8.
Research output: Contribution to journal › Article › peer-review
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T1 - 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans
AU - Wilson, R.
AU - Ainscough, R.
AU - Anderson, K.
AU - Baynes, C.
AU - Berks, M.
AU - Bonfield, J.
AU - Burton, J.
AU - Connell, M.
AU - Copsey, T.
AU - Cooper, J.
AU - Coulson, A.
AU - Craxton, M.
AU - Dear, S.
AU - Du, Z.
AU - Durbin, R.
AU - Favello, A.
AU - Fraser, A.
AU - Fulton , L.
AU - Gardner, A.
AU - Green, P.
AU - Hawkins, T.
AU - Hillier, L.
AU - Jier, M.
AU - Johnston, L
AU - Jones, M.
AU - Kershaw, J.
AU - Kirsten, J.
AU - Laisstert, N.
AU - Latreille, P.
AU - Lightning, J.
AU - Lloyd, C.
AU - Mortimore, B.
AU - O'Callaghan, M.
AU - Parsons, J.
AU - Percy , C.
AU - Rifken, L.
AU - Roopra, A.
AU - Saunders, D.
AU - Shownkeen, R.
AU - Sims, M.
AU - Smaldon, N.
AU - Smith, A.
AU - Smith, M.
AU - Sonnhammer, E.
AU - Staden, R.
AU - Sulston, J.
AU - Thierry-Mieg, J.
AU - Thomas, K.
AU - Vaudin, M.
AU - Vaughan, K.
AU - Waterston, R.
AU - Watson, A.
AU - Weinstock, L.
AU - Wilkinson-Sproatt, J.
AU - Wohldman, P.
PY - 1994/3/3
Y1 - 1994/3/3
N2 - As part of our effort to sequence the 100-megabase (Mb) genome of the nematode Caenorhabditis elegans, we have completed the nucleotide sequence of a contiguous 2,181,032 base pairs in the central gene cluster of chromosome III. Analysis of the finished sequence has indicated an average density of about one gene per five kilobases; comparison with the public sequence databases reveals similarities to previously known genes for about one gene in three. In addition, the genomic sequence contains several intriguing features, including putative gene duplications and a variety of other repeats with potential evolutionary implications.
AB - As part of our effort to sequence the 100-megabase (Mb) genome of the nematode Caenorhabditis elegans, we have completed the nucleotide sequence of a contiguous 2,181,032 base pairs in the central gene cluster of chromosome III. Analysis of the finished sequence has indicated an average density of about one gene per five kilobases; comparison with the public sequence databases reveals similarities to previously known genes for about one gene in three. In addition, the genomic sequence contains several intriguing features, including putative gene duplications and a variety of other repeats with potential evolutionary implications.
KW - Animals
KW - Caenorhabditis elegans/genetics
KW - Chromosome Mapping
KW - Databases, Factual
KW - Genes, Helminth
KW - Genes, Homeobox
KW - Molecular Sequence Data
KW - Multigene Family
KW - RNA, Transfer/genetics
KW - Repetitive Sequences, Nucleic Acid
KW - Sequence Analysis, DNA
U2 - 10.1038/368032a0
DO - 10.1038/368032a0
M3 - Article
C2 - 7906398
VL - 368
SP - 32
EP - 38
JO - Nature
JF - Nature
SN - 0028-0836
IS - 6466
ER -