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A GAL4-Driver Line Resource for Drosophila Neurobiology

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A GAL4-Driver Line Resource for Drosophila Neurobiology. / Jenett, Arnim; Rubin, Gerald; Ngo, Teri T.B. et al.
In: Cell Reports, Vol. 2, No. 4, 11.10.2012, p. 991-1001.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Jenett, A, Rubin, G, Ngo, TTB, Shepherd, D, Murphy, C, Dionne, H, Pfeiffer, B, Cavallaro, A, Hall, D, Jeter, J, Iyer, N, Fetter, D, Hausenfluck, J, Peng, H, Trautman, ET, Svirskas, RR, Meyers, EW, Iwinski, ZR, Aso, Y, DePasquale, GM, Enos, A, Hulamm, P, Lam, SCB, Li, H-H, Laverty, T, Long, F, Qu, L, Murphy, SD, Rokicki, C, Safford, T, Shaw, K, Simpson, JH, Sowell, A, Tae, S, Yu, Y & Zugates, CT 2012, 'A GAL4-Driver Line Resource for Drosophila Neurobiology', Cell Reports, vol. 2, no. 4, pp. 991-1001. https://doi.org/10.1016/j.celrep.2012.09.011

APA

Jenett, A., Rubin, G., Ngo, T. T. B., Shepherd, D., Murphy, C., Dionne, H., Pfeiffer, B., Cavallaro, A., Hall, D., Jeter, J., Iyer, N., Fetter, D., Hausenfluck, J., Peng, H., Trautman, E. T., Svirskas, R. R., Meyers, E. W., Iwinski, Z. R., Aso, Y., ... Zugates, C. T. (2012). A GAL4-Driver Line Resource for Drosophila Neurobiology. Cell Reports, 2(4), 991-1001. https://doi.org/10.1016/j.celrep.2012.09.011

CBE

Jenett A, Rubin G, Ngo TTB, Shepherd D, Murphy C, Dionne H, Pfeiffer B, Cavallaro A, Hall D, Jeter J, et al. 2012. A GAL4-Driver Line Resource for Drosophila Neurobiology. Cell Reports. 2(4):991-1001. https://doi.org/10.1016/j.celrep.2012.09.011

MLA

Jenett, Arnim et al. "A GAL4-Driver Line Resource for Drosophila Neurobiology". Cell Reports. 2012, 2(4). 991-1001. https://doi.org/10.1016/j.celrep.2012.09.011

VancouverVancouver

Jenett A, Rubin G, Ngo TTB, Shepherd D, Murphy C, Dionne H et al. A GAL4-Driver Line Resource for Drosophila Neurobiology. Cell Reports. 2012 Oct 11;2(4):991-1001. doi: 10.1016/j.celrep.2012.09.011

Author

Jenett, Arnim ; Rubin, Gerald ; Ngo, Teri T.B. et al. / A GAL4-Driver Line Resource for Drosophila Neurobiology. In: Cell Reports. 2012 ; Vol. 2, No. 4. pp. 991-1001.

RIS

TY - JOUR

T1 - A GAL4-Driver Line Resource for Drosophila Neurobiology

AU - Jenett, Arnim

AU - Rubin, Gerald

AU - Ngo, Teri T.B.

AU - Shepherd, David

AU - Murphy, Christine

AU - Dionne, Heather

AU - Pfeiffer, Barrett

AU - Cavallaro, Amanda

AU - Hall, Donald

AU - Jeter, Jennifer

AU - Iyer, Nirmal

AU - Fetter, Dona

AU - Hausenfluck, Joanna

AU - Peng, Hanchuan

AU - Trautman, Eric T.

AU - Svirskas, Robert R.

AU - Meyers, Eugene W.

AU - Iwinski, Zbigniew R.

AU - Aso, Yoshnori

AU - DePasquale, Gina M.

AU - Enos, Adrianne

AU - Hulamm, Phuson

AU - Lam, Shing Chun Benny

AU - Li, Hsing-Hsi

AU - Laverty, Todd

AU - Long, Fuhui

AU - Qu, Lei

AU - Murphy, Sean D.

AU - Rokicki, Conrad

AU - Safford, Todd

AU - Shaw, Kshiti

AU - Simpson, Julie H.

AU - Sowell, Allison

AU - Tae, Susana

AU - Yu, Yang

AU - Zugates, Christopher T.

PY - 2012/10/11

Y1 - 2012/10/11

N2 - We established a collection of 7,000 transgenic lines of Drosophila melanogaster. Expression of GAL4 in each line is controlled by a different, defined fragment of genomic DNA that serves as a transcriptional enhancer. We used confocal microscopy of dissected nervous systems to determine the expression patterns driven by each fragment in the adult brain and ventral nerve cord. We present image data on 6,650 lines. Using both manual and machine-assisted annotation, we describe the expression patterns in the most useful lines. We illustrate the utility of these data for identifying novel neuronal cell types, revealing brain asymmetry, and describing the nature and extent of neuronal shape stereotypy. The GAL4 lines allow expression of exogenous genes in distinct, small subsets of the adult nervous system. The set of DNA fragments, each driving a documented expression pattern, will facilitate the generation of additional constructs for manipulating neuronal function.

AB - We established a collection of 7,000 transgenic lines of Drosophila melanogaster. Expression of GAL4 in each line is controlled by a different, defined fragment of genomic DNA that serves as a transcriptional enhancer. We used confocal microscopy of dissected nervous systems to determine the expression patterns driven by each fragment in the adult brain and ventral nerve cord. We present image data on 6,650 lines. Using both manual and machine-assisted annotation, we describe the expression patterns in the most useful lines. We illustrate the utility of these data for identifying novel neuronal cell types, revealing brain asymmetry, and describing the nature and extent of neuronal shape stereotypy. The GAL4 lines allow expression of exogenous genes in distinct, small subsets of the adult nervous system. The set of DNA fragments, each driving a documented expression pattern, will facilitate the generation of additional constructs for manipulating neuronal function.

U2 - 10.1016/j.celrep.2012.09.011

DO - 10.1016/j.celrep.2012.09.011

M3 - Article

VL - 2

SP - 991

EP - 1001

JO - Cell Reports

JF - Cell Reports

SN - 2211-1247

IS - 4

ER -