Dr Edgar Hartsuiker
Uwch Ddarlithydd mewn Gwyddorau Biofeddygol (Bioleg Canser)
- Erthygl › Ymchwil › Adolygwyd gan gymheiriaid
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A 160-bp palindrome is a Rad50.Rad32-dependent mitotic recombination hotspot in Schizosaccharomyces pombe
Farah, J. A., Hartsuiker, E., Mizuno, K.-I., Ohta, K. & Smith, G. R., Mai 2002, Yn: Genetics. 161, 1, t. 461-8 8 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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A simple Cre-loxP method for chromosomal N-terminal tagging of essential and non-essential Schizosaccharomyces pombe genes
Werler, P. J. H., Hartsuiker, E. & Carr, A. M., 30 Ion 2003, Yn: Gene. 304, t. 133-41 9 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway
Marchetti, M. A., Kumar, S., Hartsuiker, E., Maftahi, M., Carr, A. M., Freyer, G. A., Burhans, W. C. & Huberman, J. A., 28 Mai 2002, Yn: Proceedings of the National Academy of Sciences of the United States of America. 99, 11, t. 7472-7 6 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
A supramodular FHA/BRCT-Repeat architecture mediates Nbs1 adaptor function in response to DNA damage.
Lloyd, J., Chapman, J. R., Clapperton, J. A., Haire, L. F., Hartsuiker, E., Li, J., Carr, A. M., Jackson, S. P. & Smerdon, S. J., 2 Hyd 2009, Yn: Cell. 139, 1, t. 100-111Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Collaborative Action of Brca1 and CtIP in Elimination of Covalent Modifications from Double-Strand Breaks to Facilitate Subsequent Break Repair
Nakamura, K., Kogame, T., Oshiumi, H., Shinohara, A., Sumitomo, Y., Agama, K., Pommier, Y., Tsutsui, K. M., Tsutsui, K., Hartsuiker, E., Ogi, T., Takeda, S. & Taniguchi, Y., 22 Ion 2010, Yn: PLOS Genetics. 6, 1Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions
Hartsuiker, E., Mizuno, K., Molnar, M., Kohli, J., Ohta, K. & Carr, A. M., Ebr 2009, Yn: Molecular and Cellular Biology. 29, 7, t. 1671-1681 11 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid
Blackburn, C., Tai, H., Salerno, M., Wang, X., Senan, C., Ratcliffe, I., Hartsuiker, E. & Wang, W., Chwef 2020, Yn: Data in Brief. 28, 104861.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Deoxynucleoside Salvage in Fission Yeast Allows Rescue of Ribonucleotide Reductase Deficiency but Not Spd1-Mediated Inhibition of Replication
Fleck, O., Fahnøe, U., Løvschal, K. V., Gasasira Uwamahoro, M.-F., Marinova, I. N., Kragelund, B. B., Carr, A. M., Hartsuiker, E., Holmberg, C. & Nielsen, O., 25 Ebr 2017, Yn: Genes. 8, 5, 14 t., 128.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Distinct Requirements for the Rad32Mre11 Nuclease and Ctp1CtIP in the Removal of Covalently Bound Topoisomerase I and II from DNA
Hartsuiker, E., Neale, M. J. & Carr, A. M., 16 Ion 2009, Yn: Molecular Cell. 33, 1, t. 117-123Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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Double-strand break repair and homologous recombination in Schizosaccharomyces pombe
Raji, H. & Hartsuiker, E., 15 Hyd 2006, Yn: Yeast. 23, 13, t. 963-76 14 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair
Hartsuiker, E., Vaessen, E., Carr, A. M. & Kohli, J., 3 Rhag 2001, Yn: EMBO Journal. 20, 23, t. 6660-71 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Folic acid and rhodamine labelled pH responsive hyperbranched polymers: Synthesis, characterization and cell uptake studies
Blackburn, C., Tai, H., Salerno, M., Wang, X., Hartsuiker, E. & Wang, W., Tach 2019, Yn: European Polymer Journal. 120, 109259.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Genetic Interaction Score (S-Score) Calculation, Clustering, and Visualization of Genetic Interaction Profiles for Yeast.
Roguev, A., Ryan, C. J., Xu, J., Colson, I., Hartsuiker, E. & Krogan, N., Chwef 2018, Yn: Cold Spring Harbor Protocols. 2018, 2Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Genetic Interaction Screens in Schizosaccharomyces pombe Using the Pombe Epistasis Mapper (PEM) System and a Manual Colony Replicator.
Colson, I. & Hartsuiker, E., Chwef 2018, Yn: Cold Spring Harbor Protocols. 2018, 2Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe.
Roguev, A., Ryan, C. J., Hartsuiker, E. & Krogan, N. J., Chwef 2018, Yn: Cold Spring Harbor Protocols. 2018, 2, t. 75-81 7 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication
Böckemeier, L., Kraehenbuehl, R., Keszthelyi, A., Gasasira, M. U., Vernon, E., Beardmore, R., Broberg Vågbø, C., Chaplin, D., Collins, S., Krokan, H. E., Lambert, S. A. E., Paisz, B. & Hartsuiker, E., 29 Mai 2020, Yn: Science Advances. 6, 22, 9 t., eaaz4126.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe
Manolis, K. G., Nimmo, E. R., Hartsuiker, E., Carr, A. M., Jeggo, P. A. & Allshire, R. C., 15 Ion 2001, Yn: EMBO Journal. 20, 1-2, t. 210-21 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot
Yamada, T., Mizuno, K.-I., Hirota, K., Kon, N., Wahls, W. P., Hartsuiker, E., Murofushi, H., Shibata, T. & Ohta, K., 21 Ebr 2004, Yn: EMBO Journal. 23, 8, t. 1792-803 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Screening a genome-wide S.pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.
Deshpande, G. P., Hayles, J., Hoe, K. L., Kim, D. U., Park, H. O. & Hartsuiker, E., 1 Mai 2009, Yn: DNA Repair. 8, 5, t. 672-679Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Selective Killing of BRCA2-Deficient Ovarian Cancer Cells via MRE11 Blockade
Alblihy , A., Ali , R., Algethami, M., Ritchie, A. A., Shoqafi, A., Alqahtani, S., Mesquita, K. A., Toss, M. S., Ordóñez-Morán , P., Jeyapalan, J. N., Dekker , L., Salerno, M., Hartsuiker, E., Grabowska , A. M., Rakha, E. A., Mongan, N. P. & Madhusudan, S., 30 Meh 2023, Yn: International journal of molecular sciences. 24, 13Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks
El-Khamisy, S. F., Hartsuiker, E. & Caldecott, K. W., 1 Hyd 2007, Yn: DNA Repair. 6, 10, t. 1485-95 11 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
The DNA-Binding Domain of S-pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers
Zech, J., Godfrey, E. L., Masai, H., Hartsuiker, E. & Dalgaard, J. Z., 22 Gorff 2015, Yn: PLoS ONE. 10, 7Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
The meiotic recombination hot spot ura4A in Schizosaccharomyces pombe
Baur, M., Hartsuiker, E., Lehmann, E., Ludin, K., Munz, P. & Kohli, J., Chwef 2005, Yn: Genetics. 169, 2, t. 551-61 11 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization
Rudolph, C., Kunz, C., Parisi, S., Lehmann, E., Hartsuiker, E., Fartmann, B., Kramer, W., Kohli, J. & Fleck, O., Ion 1999, Yn: Molecular and Cellular Biology. 19, 1, t. 241-50 10 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
The role of topoisomerase II in meiotic chromosome condensation and segregation in Schizosaccharomyces pombe
Hartsuiker, E., Bähler, J. & Kohli, J., Hyd 1998, Yn: Molecular Biology of the Cell. 9, 10, t. 2739-50 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Topoisomerase I regulates open chromatin and controls gene expression in vivo
Durand-Dubief, M., Persson, J., Norman, U., Hartsuiker, E. & Ekwall K., [. V., 7 Gorff 2010, Yn: EMBO Journal. 29, 13, t. 2126 - 2134Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
UV induced ubiquitination of the yeast Rad4-Rad23 complex promotes survival by regulating cellular dNTP pools
Zhou, Z., Humphryes, N., van Eijk, P., Waters, R., Yu, S. R., Kraehenbuehl, R., Hartsuiker, E. & Reed, S. H., 6 Gorff 2015, Yn: Nucleic Acids Research. 43, 15, t. 7360-7370Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Pennod › Ymchwil › Heb ei adolygu gan gymheiriaid
- Cyhoeddwyd
Detection of covalent DNA-bound Spo11 and topoisomerase complexes
Hartsuiker, E. & Tsubouchi, H. (Golygydd), 28 Ebr 2011, DNA recombination: Methods and Protocols. Springer Science and Business Media LLC, t. 65-77Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Pennod
- Pennod › Ymchwil › Adolygwyd gan gymheiriaid
- Cyhoeddwyd
Immunocytochemical techniques applied to meiotic chromosomes
Heyting, C., Dietrich, A. J., de Jong, J. H. & Hartsuiker, E., 1994, Chromosome Analysis Protocols. Gosden, J. R. (gol.). Cyfrol 29. t. 287-302 (Methods in Molecular Biology).Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Pennod › adolygiad gan gymheiriaid