Professor Alexander Yakunin

Professor In Enzyme Discovery and Application

Contact info

 

Professor Alexander Yakunin (Iakounine)

 

Office: Thoday Building, room S25

Email: a.iakounine@bangor.ac.uk

Tel: 01248 388399

 

Research focus: enzyme discovery, enzymology, enzyme applications

  1. 2024
  2. E-pub ahead of print

    Ni(II)-binding affinity of CcNikZ-II and its homologs: the role of the HH-prong and variable loop revealed by structural and mutational studies

    Diep, P., Stogios, P. J., Evdokimova, E., Savchenko, A., Mahadevan, R. & Yakunin, A. F., 31 Mar 2024, (E-pub ahead of print) In: Febs Journal.

    Research output: Contribution to journalArticlepeer-review

  3. 2023
  4. Published

    One-pot chemo-enzymatic synthesis and one-step recovery of length-variable long-chain polyphosphates from microalgal biomass

    Lin, Y-H., Nishikawa, S., Jia, T. Z., Yeh, F-I., Khusnutdinova, A., Yakunin, A., Fujishima, K. & Wang, P-H., 27 Oct 2023, In: Green Chemistry. 23

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases

    Khusnutdinova, A. N., Batyrova, K., Brown, G., Fedorchuck, T., Chai, Y. S., Skarina, T., Flick, R., Petit, A-P., Savchenko, A., Stogios, P. & Yakunin, A., Oct 2023, In: Febs Journal. 290, 20, p. 4966-4983 18 p.

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling

    Williams, G., Ma, H., Khusnutdinova, A., Yakunin, A. & Golyshin, P., Aug 2023, In: Essays in Biochemistry. 67, 4, p. 715-729 15 p., EBC20220255.

    Research output: Contribution to journalReview articlepeer-review

  7. Published

    CRISPR-induced DNA reorganization for multiplexed nucleic acid detection

    Karlikow, M., Amalfitano, E., Yang, X., Doucet, J., Chapman, A., Sadat-Moussavi, P., Homme, P., Sutyrina, P., Chang, W., Lemak, S., Yakunin, A., Dolezal, A. G., Kelley, S., Foster, L., Harpur, B. & Pardee, K., 17 Mar 2023, In: Nature Communications. 14, 1, 1505.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Thermophilic Carboxylesterases from Hydrothermal Vents of the Volcanic Island of Ischia Active on Synthetic and Biobased Polymers and Mycotoxins

    Distaso, M., Chernikova, T., Bargiela, R., Coscolín, C., Stogios, P. J., Gonzalez-Alfonso, J. L., Lemak, S., Khusnutdinova, A., Plou, F. J., Evdokimova, E., Savchenko, A., Lunev, E., Yakimov, M. M., Golyshina, O., Ferrer, M., Yakunin, A. & Golyshin, P., 28 Feb 2023, In: Applied and Environmental Microbiology. 89, 2, p. e0170422 20 p.

    Research output: Contribution to journalArticlepeer-review

  9. 2022
  10. Published

    Metabolite Damage and Damage-Control in a Minimal Genome

    Haas, D., Thamm, A. M., Sun, J., Huang, L., Sun, L., Beaudoin, G. A. W., Wise, K. S., Lema-Ortiz, C., Bruner, S. D., Breuer, M., Luthey-Schutten, Z., Lin, J., Wilson, M. A., Brown, G., Yakunin, A., Kurilyak, I., Folz, J., Fiehn, O., Glass, J. I., Hanson, A. D., Henry, C. S. & de Crecy-Lagard, V., 30 Aug 2022, In: mBio. e0163022.

    Research output: Contribution to journalArticlepeer-review

  11. 2021
  12. Published

    Structural and biochemical insights into CRISPR RNA processing by the Cas5c ribonuclease SMU1763 from Streptococcus mutans

    Lemak, S., Serbanescu, M. A., Khusnutdinova, A. N., Ruszkowski, M., Beloglazova, N., Xu, X., Brown, G., Cui, H., Tan, K., Joachimiak, A., Cvitkovitch, D. G., Savchenko, A. & Yakunin, A., Nov 2021, In: Journal of Biological Chemistry. 297, 5, 101251.

    Research output: Contribution to journalArticlepeer-review

  13. 2020
  14. Published

    A microplate screen to estimate metal-binding affinities of metalloproteins

    Diep, P., Mahadevan, R. & Yakunin, A. F., 15 Nov 2020, In: Analytical biochemistry. 609, p. 113836

    Research output: Contribution to journalArticlepeer-review

  15. Published

    Proteome cold-shock response in the extremely acidophilic archaeon, Cuniculiplasma divulgatum

    Bargiela, R., Lanthaler, K., Potter, C., Ferrer, M., Yakunin, A., Paizs, B., Golyshin, P. & Golyshina, O., 19 May 2020, In: Microorganisms . 8, 5

    Research output: Contribution to journalArticlepeer-review

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