1. 2016
2. Published

   A randomised, patient-assessor blinded, sham-controlled trial of external noninvasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial): study protocol for a randomised controlled trial

   Johnson, S., Goebel, A., Richey, R., Holmes, E. & Hughes, D., 6 Dec 2016, In: Trials. 17, 574.

   Research output: Contribution to journal › Article › peer-review

3. 2017
4. Published

   Societal perspective on access to publicly subsidised medicines: A cross sectional survey of 3080 adults in Australia

   Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 1 Mar 2017, In: PLoS ONE.

   Research output: Contribution to journal › Article › peer-review

5. Published

   Economic Studies in Motor Neurone Disease: A Systematic Methodological Review

   Moore, A., Young, C. A. & Hughes, D., Apr 2017, In: Pharmacoeconomics. 35, 4, p. 397-413

   Research output: Contribution to journal › Article › peer-review

6. Published

   Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis

   Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., Hardwick, B., Hickey, H., Hughes, D., Woo, P., Benton, D., Edelsten, C. & Beresford, M. W., 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1637-1646

   Research output: Contribution to journal › Article › peer-review

7. Published

   Core items for a standardised resource-use measure (ISRUM):expert Delphi consensus survey

   Thorn, J., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., 7 May 2017, p. P265. 1 p.

   Research output: Contribution to conference › Poster › peer-review

8. Published

   Health economics analysis plans: the current state of play

   Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 7 May 2017, p. P144. 1 p.

   Research output: Contribution to conference › Poster › peer-review

9. Published

   Patient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations

   Ridyard, C. & Hughes, D., 7 May 2017, p. P141. 1 p.

   Research output: Contribution to conference › Poster › peer-review

10. Published

    Patient preferences for outcomes in clinical trials: implications for medicines optimization

    Holmes, E., Marson, A. G. & Hughes, D., 8 May 2017, In: Trials. 18 (Suppl 1), O18, p. 192 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

11. Published

    Affordable orphan drugs: A role for not-for-profit organisations

    Davies, E. H., Fulton, E., Brook, D. & Hughes, D., Jul 2017, In: British Journal of Clinical Pharmacology. 83, 7, p. 1595-1601

    Research output: Contribution to journal › Article › peer-review

12. Published

    Comparison of regression methods for the cost effectiveness analysis of clinical trials with a small population size: the sycamore and folated trials

    Culeddu, G., Hughes, D. & Welton, N., 10 Jul 2017.

    Research output: Contribution to conference › Poster › peer-review

13. Published

    Using Routinely Recorded Data in the UK to Assess Outcomes in a Randomised Controlled Trial: The Trials of Access

    Powell, G., Bonnett, L., Smith, C. T., Hughes, D., Williamson, P. & Marson, A., 23 Aug 2017, In: Trials. 18, 11 p., 389.

    Research output: Contribution to journal › Article › peer-review

14. Published

    Continuous subcutaneous insulin infusion compated to multiple daily injection regimens in children and yung people at diagnosis of type 1 diabetes: A pragmatic randomised controlled trial and economic evaluation (scipi trial)

    Blair, J., Mckay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., John, G., Hughes, D. & Gamble, C., Sept 2017, p. 22-23.

    Research output: Contribution to conference › Abstract › peer-review

15. Published

    Carer-administration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARIAD)

    Wilkinson, C., Poolman, M., Roberts, J., Wee, B., Hiscock, J., Hughes, D., Nelson, A., Perkins, P., Johnstone, R. P., Reymond, E., Foster, B., O'Connor, J., Jones, S., Hoare, Z., Roberts, R., Byrne, A., Healy, S. & Lewis, P., 1 Sept 2017.

    Research output: Contribution to conference › Poster › peer-review

16. Published

    Cost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial

    Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Sept 2017, In: Frontiers in Pharmacology. 8, 644.

    Research output: Contribution to journal › Article › peer-review

17. Published

    Cost-effectiveness of HLA-B*15:02 screening in Malaysia

    Plumpton, C. & Hughes, D., Oct 2017, In: British Journal of Dermatology. 177, 4, p. 904-905

    Research output: Contribution to journal › Comment/debate

18. Published

    Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout

    Plumpton, C., Alfirevic, A., Pirmohamed, M. & Hughes, D., 1 Oct 2017, In: Rheumatology. 56, 10, p. 1729-1739

    Research output: Contribution to journal › Article › peer-review

19. Published

    Renal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment

    Hagemi, A., Plumpton, C. & Hughes, D., 2 Oct 2017, In: BMC Nephrology. 18, 305.

    Research output: Contribution to journal › Article › peer-review

20. Published

    Continuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis

    Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A582

    Research output: Contribution to journal › Article › peer-review

21. Published

    Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

    Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A590

    Research output: Contribution to journal › Article › peer-review

22. Published

    Use Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients

    Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A580

    Research output: Contribution to journal › Article › peer-review

23. Published

    Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica

    Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Oct 2017, In: Health Technology Assessment. 21, 60, p. 1-180 180 p.

    Research output: Contribution to journal › Article › peer-review

24. Published

    Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

    Ridyard, C., Blair, J. & Hughes, D., Nov 2017, In: Value in Health. 20, 9, p. A481 - A482

    Research output: Contribution to journal › Article › peer-review

25. Published

    Decision analytic modelling methods for the assessing the effectiveness of treatment sequences for clinical and economic decision making: a methodological review

    Lewis, R., Hughes, D. & Wilkinson, C., 30 Nov 2017, In: Value in Health. 20, 9, p. A748 1 p.

    Research output: Contribution to journal › Article › peer-review

26. 2018
27. Published

    Impact of non-adherence on the safety and efficacy of uric acid lowering therapies in the treatment of gout

    Hill McManus, D., Soto, E., Marshall, S., Lane, S. & Hughes, D., Jan 2018, In: British Journal of Clinical Pharmacology. 84, 1, p. 142-152

    Research output: Contribution to journal › Article › peer-review

28. Published

    Impact on the phased abolition of co-payments on the utilisation of selected prescription medicines in Wales

    Alam, M. F., Cohen, D., Dunstan, F., Hughes, D. & Routledge, P. A., Jan 2018, In: Health Economics. 27, 1, p. 236-243

    Research output: Contribution to journal › Article › peer-review

29. Published

    Rare disease prevention and treatment: The need for a level playing field

    Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247

    Research output: Contribution to journal › Article › peer-review

30. Published

    Economics of pharmacogenetic guided treatments: Underwhelming or overstated?

    Hughes, D., May 2018, In: Clinical Pharmacology and Therapeutics. 103, 5, p. 749-751

    Research output: Contribution to journal › Article › peer-review

31. Published

    New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes

    Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., May 2018, In: Pharmacoeconomics. 36, 5, p. 613-624 12 p.

    Research output: Contribution to journal › Article › peer-review

32. Published

    Societal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods

    Bourke, S. M., Plumpton, C. & Hughes, D., 9 May 2018, In: Value in Health. 21, 5, p. 538-546

    Research output: Contribution to journal › Article › peer-review

33. Published

    Core items for a standardized resource-use measure (ISRUM): expert Delphi consensus survey

    Thom, J., Brookes, S. T., Ridyard, C., Riley, R., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., Jun 2018, In: Value in Health. 21, 6, p. 640-649

    Research output: Contribution to journal › Article › peer-review

34. Published

    Do guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review

    Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Jul 2018, In: Thorax. 73, 7, p. 670-673

    Research output: Contribution to journal › Letter › peer-review

35. Published

    ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

    De Geest, S., Zullig, L. L., Dunbar-Jacob, J., Helmy, R., Hughes, D., Wilson, I. & Vrijens, B., 3 Jul 2018, In: Annals of Internal Medicine. 169, 1, p. 30-35

    Research output: Contribution to journal › Article › peer-review

36. Published

    Lessons learnt from a discontinued randomised controlled trial: Adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC)

    Williams, N., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Jul 2018, In: Trials. 19, 408.

    Research output: Contribution to journal › Article › peer-review

37. Published

    Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT

    Blair, J., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. & Gamble, C., Aug 2018, In: Health Technology Assessment. 22, 42, p. 1-112 112 p.

    Research output: Contribution to journal › Article › peer-review

38. Published

    Letter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma

    Jenkinson, M., Weber, D., Haylock, B., Sherratt, F., Young, B., Weller, M., Bulbeck, H., Culeddu, G., Hughes, D., Brain, A., Das, K., Preusser, M., Francis, P. & Gamble, C., 17 Aug 2018, In: Journal of Neurology, Neurosurgery and Psychiatry.

    Research output: Contribution to journal › Letter › peer-review

39. Published

    Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care

    Swift, B., Jain, L., White, C., Chandrasekaran, V., Bhandari, A., Hughes, D. & Jadhav, P., Sept 2018, In: Clinical and Translational Science. 11, 5, p. 450-460 11 p.

    Research output: Contribution to journal › Article › peer-review

40. Published

    Mapping ALSFRS-R and ALSUI to EQ-5D in patients with motor neurone disease

    Moore, A., Young, C. A. & Hughes, D., Nov 2018, In: Value in Health. 21, 11, p. 1322-1329

    Research output: Contribution to journal › Article › peer-review

41. Published

    Impact of non-adherence and flare resolution on the cost effectiveness of treatments for gout: Application of a linked pharmacometric/pharmacoeconomic model

    Hill-McManus, D., Marshall, S., Soto, E., Lane, S. & Hughes, D., Dec 2018, In: Value in Health. 21, 12, p. 1373-1381

    Research output: Contribution to journal › Article › peer-review

42. Published

    Cost-Effectiveness Analysis of the Use of Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing in Primary Care

    Holmes, E., Harris, S. D., Hughes, A., Craine, N. & Hughes, D., 7 Dec 2018, In: Antibiotics. 7, 4, 19 p., 106.

    Research output: Contribution to journal › Article › peer-review

43. 2019
44. Published

    Community views on factors affecting medicines resource allocation: Cross-sectional survey of 3080 adults in Australia

    Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 2019, In: Australian Health Review . 43, 3, p. 254-260

    Research output: Contribution to journal › Article › peer-review

45. Published

    CARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial

    Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Feb 2019, In: Trials. 20, 1, 16 p., 105.

    Research output: Contribution to journal › Article › peer-review

46. Published

    Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis

    Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. 415-424

    Research output: Contribution to journal › Article › peer-review

47. Published

    Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.

    Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25

    Research output: Contribution to journal › Letter › peer-review

48. Published

    Patient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs

    Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Mar 2019, In: Clinical Pharmacology and Therapeutics. 105, 3, p. 672-683 12 p.

    Research output: Contribution to journal › Article › peer-review

49. Published

    Systematic Review: Outcomes and adverse events from randomised trials in Crohn's disease

    Catt, H., Hughes, D., Kirkham, J. K. & Bodger, K., Apr 2019, In: Alimentary Pharmacology and Therapeutics. 49, 8, p. 978-996 19 p.

    Research output: Contribution to journal › Article › peer-review

50. Published

    Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

    de Geest, S., Zullig, L. L., Dunbar-Jacob, J., Hughes, D., Wilson, I. & Vrijens, B., 1 Apr 2019, In: European Journal of Cardiovascular Nursing. 18, 4, p. 258-259 2 p.

    Research output: Contribution to journal › Editorial › peer-review

51. Published

    Continuous subcutaneous insulin infusion versus multiple daily injection regimens in children and young people at diagnosis of type 1 diabetes: pragmatic randomised controlled trial and economic evaluation

    Blair, J. C., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. A. & Gamble, C., 3 Apr 2019, In: British Medical Journal. 365, p. l1226 l1226.

    Research output: Contribution to journal › Article › peer-review

52. Published

    Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT

    Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D., McKay, A., Rosala_Hanna, A., Williamson, P. R., Hardwick, B., Hickey, H., Rainford, N., Kolamunnage-Dona, R., Culeddu, G., Plumpton, C., Wood, E., Compeyrot-Lacassagne, S., Woo, P., Eldesten, C. & Beresford, M. W., 10 Apr 2019, In: Health Technology Assessment. 23, 15, p. 1-174 174 p.

    Research output: Contribution to journal › Article › peer-review

53. Published

    Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus

    Crudgington, H., Rogers, M., Bray, L., Carter, B., Currier, J., Gibbon, F., Hughes, D., Lyle, S., Roberts, D., Smith, C. T., Gringras, P., Pal, D. & Morris, C., May 2019, In: Epilepsia. 60, 5, p. 857-871

    Research output: Contribution to journal › Article › peer-review

54. Published

    Cost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework

    Plumpton, C., Pirmohamed, M. & Hughes, D., Jun 2019, In: Clinical Pharmacology and Therapeutics. 105, 6, p. 1429-1438

    Research output: Contribution to journal › Article › peer-review