Dyfrig Hughes - Research outputs

Published

Eliciting patients' preferences using a discrete choice experiment questionnaire: the role played by qualitative data in questionnaire design

Hughes, D., Longo, M., Hughes, D. A., Myles, S. & Lisles, C., 1 Mar 2006.

Research output: Contribution to conference › Paper

Published

Empirical analysis of the relationship between dose and duration of drug action

Hughes, D. & Hughes, D. A., 1 Jun 2005.

Research output: Contribution to conference › Paper

Published

Engaging with the MRC Methodology Hubs – NWHTMR.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Enhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.

Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Jan 2010.

Research output: Contribution to conference › Paper

Published

EstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): Protocol for a systematic review, network meta-analysis and cost-effectiveness analysis using individual participant data (IPD)

Cividini, S., Sinha, I., Donegan, S., Maden, M., Culeddu, G., Rose, K., Fulton, O., Hughes, D., Turner, S. & Smith, C. T., 5 Feb 2021, In: BMJ Open. 11, e040528.

Research output: Contribution to journal › Article › peer-review

Published

Estimating Drug Costs in Economic Evaluations in Ireland and the UK: An Analysis of Practice and Research Recommendations.

Hughes, D., Hughes, D. A., Tilson, L. & Drummond, M. F., 1 May 2009, In: Pharmacoeconomics. 27, 8, p. 635-643

Research output: Contribution to journal › Article › peer-review

Published

Estimation of the impact of noncompliance on pharmacokinetics: an analysis of the influence of dosing regimens

Hughes, D. & Hughes, D. A., 1 Dec 2008, In: British Journal of Clinical Pharmacology. 65, 6, p. 871-878

Research output: Contribution to journal › Article › peer-review

Published

Evaluation of a consultant audit and feedback programme to improve the quality of antimicrobial prescribing in acute medical admissions

Hughes, D., Roberts, E., Dawoud, D. M., Hughes, D. A. & Cefai, C., 1 Oct 2015, In: International Journal of Pharmacy Practice. 23, 5, p. 333-339

Research output: Contribution to journal › Article › peer-review

E-pub ahead of print

Evidence following conditional NICE technology appraisal recommendations: A critical analysis of methods, quality and risk of bias

Pijeira Perez, Y. & Hughes, D., 9 Sept 2024, (E-pub ahead of print) In: Pharmacoeconomics.

Research output: Contribution to journal › Article › peer-review

Published

Evidence to support inclusion of pharmacogenetic biomarkers in randomised controlled trials

Johnson, D., Jorgensen, A., Hughes, D. & Pirmohamed, M., 1 Sept 2019, In: Journal of Personalized Medicine. 9, 3, 19 p., 42.

Research output: Contribution to journal › Review article › peer-review

Published

Experiences of men who have sex with men when initiating, implementing, and persisting with HIV pre-exposure prophylaxis

Gillespie, D., Wood, F., Williams, A., Ma, R., de Bruin, M., Hughes, D., Jones, A. T., Couzens, Z. & Hood, K., Aug 2022, In: Health Expectations. 25, 4, p. 1332-1341 10 p.

Research output: Contribution to journal › Article › peer-review

Published

Extended-release pharmacotherapy for opioid use disorder (EXPO): protocol for an open-label randomised controlled trial of the effectiveness and cost-effectiveness of injectable buprenorphine versus sublingual tablet buprenorphine and oral liquid methadone

Marsden, J., Kelleher, M., Hoare, Z., Hughes, D., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Scott, G., Turner, S., Vanderwaal, R., Wareham, A., Gilvarry, E. & Mitcheson, L., 19 Aug 2022, In: Trials. 23, 1, 697.

Research output: Contribution to journal › Article › peer-review

Published

Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment

Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 Jan 2007, In: Value in Health. 10, 3, p. A23

Research output: Contribution to journal › Article › peer-review

Published

Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment

Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Falls and hip-fractures: A cost-effectiveness analysis of risk assessment and interventions for community-dwelling older people

Hughes, D., Gwynne, D., Hughes, D. A. & Edwards, R. T., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

Hughes, D. & Hughes, D. A., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

Hughes, D., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Feasibility, validity and reliability of the Welsh version of the EQ-5D health status questionnaire.

Hughes, D. & Hughes, D. A., 1 Oct 2007, In: Quality of Life Research. 16, 8, p. 1419-1423

Research output: Contribution to journal › Article › peer-review

Published

Feasibility, validity, and reliability of the Welsh version of the EQ-5D health status questionnaire

Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A189

Research output: Contribution to journal › Article › peer-review

Published

Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial.

Russell, I. T., Slegg, G. P., Roberts, S. H., Bedson, E., Hughes, D., Lloyd, K., Moat, S., Pirmohamed, M., Slegg, G., Tranter, R., Whitaker, R., Wilkinson, C. & Russell, I., 15 Nov 2007, In: BMC Psychiatry. 7, 1, p. 65

Research output: Contribution to journal › Article › peer-review

Published

Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation

Bedson, E., Bell, D., Carr, D., Carter, B., Hughes, D., Jorgensen, A., Lewis, H., Lloyd, K., McCaddon, A., Moat, S., Pink, J., Pirmohamed, M., Roberts, S., Russell, I., Sylvestre, Y., Tranter, R., Whitaker, R., Wilkinson, C. & Williams, N., Jul 2014, In: Health Technology Assessment. 18, 48, p. 1-159

Research output: Contribution to journal › Article › peer-review

Published

Follow-up of cancer in primary care versus secondary care: systematic review

Lewis, R. A., Neal, R. D., Williams, N. H., France, B., Hendry, M., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., 1 Jul 2009, In: British Journal of General Practice. 59, 564, p. e234-e247

Research output: Contribution to journal › Article › peer-review

Published

Follow-up of cancer patients in primary care versus secondary care: systematic review.

Hughes, D., Lewis, R., Neal, R., Williams, N., France, B., Wilkinson, C., Hendry, M., Russell, D., Hughes, D. A., Russell, I. T., Stuart, N. S. & Weller, D., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

From NCE to NICE: the role of pharmacoeconomics

Hughes, D. & Hughes, D. A., 1 Sept 2010, In: British Journal of Clinical Pharmacology. 70, 3, p. 317-319

Research output: Contribution to journal › Article › peer-review

Published

From efficacy to cost-effectiveness: Impact of patient compliance

Hughes, D. & Hughes, D. A., 1 Feb 2008.

Research output: Contribution to conference › Paper

Published

From efficacy to cost-effectiveness: accounting for non-compliance in pharmacoeconomics

Hughes, D. & Hughes, D. A., 1 May 2002.

Research output: Contribution to conference › Paper

Published

From efficacy to effectiveness and cost-effectiveness: modelling possibilities

Hughes, D. & Hughes, D. A., 1 Nov 2004.

Research output: Contribution to conference › Paper

Published

Generalisability and Cost-Impact of Antibiotic-Impregnated Central Venous Catheters for Reducing Risk of Bloodstream Infection in Paediatric Intensive Care Units in England

Harron, K., Mok, Q., Hughes, D., Muller-Pebody, B., Parslow, R., Ramnarayan, P. & Gilbert, R., 21 Mar 2016, In: PLoS ONE. 11, 3, p. e0151348

Research output: Contribution to journal › Article › peer-review

Published

Generic and therapeutic substitutions in the UK: are they a good thing?

Hughes, D., Duerden, M. G. & Hughes, D. A., 1 Sept 2010, In: British Journal of Clinical Pharmacology. 70, 3, p. 335-341

Research output: Contribution to journal › Article › peer-review

Published

Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.

Hughes, D., Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., Van Eker, D., Stevens, L., Hawkins, K., Toh, C. H., Kamali, F., Daly, A. K., Fitzmaurice, D., Coffey, A., Williamson, P. R., Park, B. K., Deloukas, P. & Pirmohamed, M., 1 Oct 2009, In: Pharmacogenetics and Genomics. 19, 10, p. 800-812

Research output: Contribution to journal › Article › peer-review

Published

HLA-B*5701 and abacavir hypersensitivity - Reply.

Hughes, D., Hughes, D. A., Park, B. K. & Pirmohamed, M., 1 Nov 2004, In: Pharmacogenetics. 14, 11, p. 784

Research output: Contribution to journal › Article › peer-review

Published

HTAs and rare diseases: How to assess their cost-effectiveness

Hughes, D., Phillips, C. J. & Hughes, D. A., 1 Nov 2011, In: Pharmaceuticals Policy and Law. 13, 3-4, p. 161-165

Research output: Contribution to journal › Article › peer-review

Published

Have infection control and prevention measures resulted in any adverse outcomes for care home and domiciliary care residents and staff? Report number: RR_00018 (November 2021)

Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 1 Nov 2021, 36 p.

Research output: Book/Report › Other report › peer-review

Published

Health Economics Analysis Plans: Where Are We Now?

Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 3 Nov 2016, p. A397. 1 p.

Research output: Contribution to conference › Poster › peer-review

Published

Health and economic outcomes: Why compliance matters

Hughes, D. & Hughes, D. A., 1 Apr 2006.

Research output: Contribution to conference › Paper

Published

Health economic aspects of patient non-compliance

Hughes, D., Hughes, D. A., Davies, M. (Editor) & Kermani, F. (Editor), 1 Jan 2006, Patient Compliance: Sweetening the Pill. 2006 ed. Gower Publishing, p. 23-40

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Published

Health economics analysis plans: the current state of play

Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 7 May 2017, p. P144. 1 p.

Research output: Contribution to conference › Poster › peer-review

Published

Health utilities and costs for Motor Neurone Disease

Moore, A., Young, C. A. & Hughes, D., Nov 2019, In: Value in Health. 22, 11, p. 1257-1265

Research output: Contribution to journal › Article › peer-review

Published

Health utilities and costs for neuromyelitis optica spectrum disorder

Hughes, D., Bourke, S., Jones, A., Bhatt, R., Huda, S., Mutch, K. & Jacob, A., 2022, In: Orphanet Journal of Rare Diseases. 17, 11 p., 159.

Research output: Contribution to journal › Article › peer-review

Published

Health utilities and quality-adjusted life years for patients with amyotrophic lateral sclerosis receiving reldesemtiv or placebo in FORTITUDE-ALS

Gebrehiwet, P., Meng, L., Saroccoa, P., Wei, J., Wolff, A. A., Butzner, M., Chio, A., Andrews, J. A., Genge, A., Hughes, D., Jackson, C. E., Lechtzin, N., Miller, T. M. & Shefner, J. M., 31 Mar 2023, In: Journal of Medical Economics. 26, 1, p. 488-493 6 p.

Research output: Contribution to journal › Article › peer-review

Published

Identification Of Items For A Standardised Resource-Use Measure: Review Of Current Instruments

Thorn, J. C., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S. & Hollingworth, W., Nov 2015.

Research output: Contribution to conference › Paper › peer-review

Published

Identification and Assessment of Adherence-Enhancing Interventions in Studies Assessing Medication Adherence Through Electronically Compiled Drug Dosing Histories: A Systematic Literature Review and Meta-Analysis

Hughes, D., Holmes, E. A., Demonceau, J., Ruppar, T., Kristano, P., Hughes, A. D., Fargher, E., Przemyslaw, K., De Geest, S., Dobbels, F., Lewek, P., Urquhart, J. & Vrijens, B., 1 May 2013, In: Drugs. 73, 6, p. 545-562

Research output: Contribution to journal › Article › peer-review

Published

Impact of Interventions on Medication Adherence and Blood Pressure Control in Patients with Essential Hypertension: A Systematic Review by the ISPOR Medication Adherence and Persistence Special Interest Group

Hughes, D., Gwadry-Sridhar, F. H., Manias, E., Lal, L., Salas, M., Hughes, D. A., Ratzki-Leewing, A. & Grubisic, M., 1 Jul 2013, In: Value in Health. 16, 5, p. 863-871

Research output: Contribution to journal › Article › peer-review

Published