A Pragmatic randomized controlled trial of thiopurine methyltransferase genotyping prior to azathioprine treatment: the TARGET study.

Newman, W., Payne, K., Tricker, K., Roberts, S., Fargher, E., Pushpakom, S., Alder, J., Sidgwick, G., Payne, D., Elliott, R. A., Heise, M., Elles, R., Ramsden, S., Andrews, J., Houston, B., Qasim, F., Shaffer, J., Griffiths, C., Ray, D., Bruce, I. & Ollier, W., 21 Jun 2011, In: Pharmacogenomics. 12, 6, p. 815-826

Research output: Contribution to journal › Article › peer-review

A model-based cost-utility analysis of an automated notification system for deteriorating patients on general wards

Holmes, E., Hughes, D. & Subbe, C., 2 May 2024, In: PLoS ONE. 19, 5, p. e0301643 e0301643.

Research output: Contribution to journal › Article › peer-review

A new taxonomy for describing and defining adherence to medications

Holmes, E. A., Hughes, D., Morrison, V. L., Vrijens, B., De Geest, S., Hughes, D. A., Prezemyslaw, K., Demonceau, J., Ruppar, T., Dobbels, F., Fargher, E., Morrison, V., Lewek, P., Matyjaszczyk, M., Mshelia, C., Clyne, W., Aronson, J. K. & Urquhart, J., 1 May 2012, In: British Journal of Clinical Pharmacology. 73, 5, p. 691-705

Research output: Contribution to journal › Article › peer-review

A randomised, patient-assessor blinded, sham-controlled trial of external noninvasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial): study protocol for a randomised controlled trial

Johnson, S., Goebel, A., Richey, R., Holmes, E. & Hughes, D., 6 Dec 2016, In: Trials. 17, 574.

Research output: Contribution to journal › Article › peer-review

Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria

Lotsch, F., Auer-Hackenberg, L., Groger, M., Rehman, K., Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., de Geest, S., Dobbels, F., Vrijens, B., Kardas, P., Hughes, D. & Ramharter, M., May 2015, In: Wiener klinische Wochenschrift. 127, 9-10, p. 379-384

Research output: Contribution to journal › Article › peer-review

Attitudes towards epilepsy in the UK population: Results from a 2018 national survey

Holmes, E., Bourke, S. & Plumpton, C., Feb 2019, In: Seizure: European Journal of Epilepsy. 65, p. 12-19

Research output: Contribution to journal › Article › peer-review

CARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial

Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Feb 2019, In: Trials. 20, 1, 16 p., 105.

Research output: Contribution to journal › Article › peer-review

Carer administration of as-needed sub-cutaneous medication for breakthrough symptoms in people dying at home: the CARiAD feasibility RCT

Poolman, M., Roberts, J., Wright, S., Hendry, A., Goulden, N., Holmes, E., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., O'Connor, J., Foster, B., Reymond, L., Healy, S., Lewis, P., Wee, B., Johnstone, R. P., Roberts, R., Parkinson, A., Roberts, S. & Wilkinson, C., 2 Jun 2020, In: Health Technology Assessment. 24, 25, 150 p.

Research output: Contribution to journal › Article › peer-review

Conducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches

Hughes, D., Charles, J. M., Dawoud, D. M., Edwards, R. T., Holmes, E. A., Jones, C. L., Parham, P., Plumpton, C., Ridyard, C. O., Lloyd-Williams, H., Wood, E. M. & Yeo, S., May 2016, In: Pharmacoeconomics. 34, 5, p. 447-461

Research output: Contribution to journal › Article › peer-review

Cost-Effectiveness Analysis of the Use of Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing in Primary Care

Holmes, E., Harris, S. D., Hughes, A., Craine, N. & Hughes, D., 7 Dec 2018, In: Antibiotics. 7, 4, 19 p., 106.

Research output: Contribution to journal › Article › peer-review

Current use of pharmacogenetic testing: a national survey of thiopurine methyltransferase testing prior to azathioprine prescription.

Holmes, E. A., Fargher, E. A., Tricker, K., Newman, W., Elliott, R., Roberts, S. A., Shaffer, J. L., Bruce, I. & Payne, K., 1 Apr 2007, In: Journal of Clinical Pharmacy and Therapeutics. 32, 2, p. 187-195

Research output: Contribution to journal › Article › peer-review

Developing an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project

Holmes, E., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Foster, D., Hardman, K., Bell, S., Marson, A., Hughes, D. & Noble, A. J., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 28-37 10 p.

Research output: Contribution to journal › Article › peer-review

Developing feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed methods study

Noble, A. J., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Morris, B., Hughes, D., Marson, T. & Holmes, E., Aug 2024, In: Health Services and Delivery Research (HS&DR). 12, 24

Research output: Contribution to journal › Article › peer-review

Developing patient-centred, feasible alternative care for adult emergency department users with epilepsy: Protocol for the mixed-methods observational ‘Collaborate’ project.

Noble, A. J., Mathieson, A., Ridsdale, L., Holmes, E., Morgan, M., McKinlay, A., Dickson, J., Jackson, M., Hughes, D., Goodacre, S. & Marson, A. G., 2 Nov 2019, In: BMJ Open. 9, 11, e031696.

Research output: Contribution to journal › Article › peer-review

Exploring Preferred Dental Services of Swiss Older People for When They Become Dependent

Chebib, N., Abou-Ayash, S., Maniewicz, S., Srinivasan, M., Hill, H., McKenna, G., Holmes, E., Schimmel, M., Brocklehurst, P. & Muller, F., Nov 2020, In: Swiss Dental Journal. 130, 11, p. 876-884

Research output: Contribution to journal › Article › peer-review

Exploring preferences of older adults for dental services: A pilot multi-national discrete choice experiment

Chebib, N., Holmes, E., Maniewicz, S., Abou-Ayash, S., Srinivasan, M., McKenna, G., Kossioni, A., Schimmel, M., Muller, F. & Brocklehurst, P., Jun 2024, In: Gerodontology. 41, 2, p. 220-230

Research output: Contribution to journal › Article › peer-review

Identification and Assessment of Adherence-Enhancing Interventions in Studies Assessing Medication Adherence Through Electronically Compiled Drug Dosing Histories: A Systematic Literature Review and Meta-Analysis

Hughes, D., Holmes, E. A., Demonceau, J., Ruppar, T., Kristano, P., Hughes, A. D., Fargher, E., Przemyslaw, K., De Geest, S., Dobbels, F., Lewek, P., Urquhart, J. & Vrijens, B., 1 May 2013, In: Drugs. 73, 6, p. 545-562

Research output: Contribution to journal › Article › peer-review

Investigating preferences for support with life after stroke: a discreet choice experiment

Holmes, E. A., Plumpton, C. O., Roberts, G. W., Burton, C. R., Farghrer, E., Plumpton, C., Roberts, G., Owen, H. & Roberts, E., 8 Feb 2014, In: BMC Health Services Research. 14, 63, p. 1-13

Research output: Contribution to journal › Article › peer-review

Is shared care with annual hospital review better value for money than predominantly hospital-based care in patients with established stable rheumatoid arthritis?

Holmes, E. A., Davies, L. M., Fargher, E. A., Tricker, K., Dawes, P., Scott, D. L. & Symmons, D., 1 May 2007, In: Annals of the Rheumatic Diseases. 66, 5, p. 658-663

Research output: Contribution to journal › Article › peer-review

Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial

Johnson, S., Marshall, A., Hughes, D., Holmes, E., Henrich, F., Nurmikko, T., Sharma, M., Frank, B., Bassett, P., Marshall, A. & Goebel, A., 6 Nov 2021, In: Journal of Translational Medicine. 19, 1, 458.

Research output: Contribution to journal › Article › peer-review

New advice on switching antiepileptic drugs might be a false economy

Holmes, E. A., Plumpton, C. O., Hughes, D., Holmes, E., Plumpton, C., Duerden, M., Marson, T. & Hughes, D. A., 16 Dec 2013, In: British Medical Journal. 347

Research output: Contribution to journal › Article › peer-review

Patient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs

Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Mar 2019, In: Clinical Pharmacology and Therapeutics. 105, 3, p. 672-683 12 p.

Research output: Contribution to journal › Article › peer-review

Patients' and healthcare professionals' views on pharmacogenetic testing and its future delivery in the NHS.

Holmes, E. A., Fargher, E. A., Eddy, C., Newman, W., Qasim, F., Tricker, K., Elliott, R. A. & Payne, K., 1 Sept 2006, In: Pharmacogenomics. 8, 11, p. 1511-1519

Research output: Contribution to journal › Article › peer-review

People with dementia and caregiver preferences for digital life story work service interventions: A discrete choice experiment and digital survey

O' Philbin, L., Woods, R. & Holmes, E., 1 Feb 2020, In: Aging and Mental Health. 24, 2, p. 353-361

Research output: Contribution to journal › Article › peer-review

Pharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery

Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Jul 2015, In: British Journal of Clinical Pharmacology. 80, 5, p. 1149-1159

Research output: Contribution to journal › Article › peer-review

Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research

Holmes, E. A., Morrison, V. L. & Hughes, D., 8 Dec 2014, In: Value in Health. 17, 8, p. 863-876

Research output: Contribution to journal › Article › peer-review

Predictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey

Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Mar 2015, In: Value in Health. 18, 2, p. 206-216

Research output: Contribution to journal › Article › peer-review

Preferences of people with diabetes for diabetic retinopathy screening: a discrete choice experiment

Holmes, E. A., Yeo, S. T., Edwards, R. T., Fargher, E. A., Luzio, S. D., Thomas, R. L. & Owens, D. R., 1 Jul 2012, In: Diabetic Medicine. 29, 7, p. 869-877

Research output: Contribution to journal › Article › peer-review

Seizure First Aid Training For people with Epilepsy (SAFE) frequently attending emergency departments and their significant others: results of a UK multi-centre randomised controlled pilot trial

Noble, A. J., Snape, D., Nevitt, S., Holmes, E., Morgan, M., Smith, C. T., Hughes, D., Buchanan, M., McVicar, J., MacCallum, E., Goodacre, S., Rinsdale, L. & Marson, A. G., 16 Apr 2020, In: BMJ Open. 10, 4, e035516.

Research output: Contribution to journal › Article › peer-review

Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project

Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 17-27 11 p.

Research output: Contribution to journal › Article › peer-review

Supporting People With Type 2 Diabetes in the Effective Use of Their Medicine Through Mobile Health Technology Integrated With Clinical Care to Reduce Cardiovascular Risk: Protocol for an Effectiveness and Cost-effectiveness Randomized Controlled Trial

Farmer, A. J., Jones, L., Newhouse, N., Kenning, C., Williams, N., Chi, Y., Bartlett, K., Plumpton, C., McSharry, J., Cholerton, R., Holmes, E., Robinson, S., Allen, J., Gudgin, B., Velardo, C., Rutter, H., Horne, R., Tarassenko, L., Williams, V., Locock, L., Rea, R., Yu, L.-M., Hughes, D., Bower, P. & French, D. P., 21 Feb 2022, In: JMIR Research Protocols. 11, 2, e32918.

Research output: Contribution to journal › Article › peer-review

Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol

Farmer, A. J., Allen, J., Bartlett, K., Bower, P., Chi, Y., French, D. P., Gudgin, B., Holmes, E., Horne, R., Hughes, D., Kenning, C., Locock, L., McSharry, J., Miles, L., Newhouse, N., Rea, R., Riga, J., Tarassenko, L., Velardo, C., Williams, N., Williams, V. & Yu, L.-M., 29 Dec 2019, In: BMJ Open. 9, 12, e033504.

Research output: Contribution to journal › Article › peer-review

Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial

SuMMiT-D Collaborative Group , 25 Jan 2024, (E-pub ahead of print) In: Pilot and Feasibility Studies. 10, 1, 15.

Research output: Contribution to journal › Article › peer-review

TPMT testing in rheumatology: any better than routine monitoring?

Holmes, E. A., Payne, K., Newman, W., Fargher, E. A., Tricker, K., Bruce, I. N. & Ollier, W. E., 1 May 2007, In: Rheumatology. 46, 5, p. 727-729

Research output: Contribution to journal › Article › peer-review

Understanding the interactions that children and young people have with their natural and built environments: A survey to identify targets for active travel behaviour change in Wales

Holmes, E., Arkesteijn, M., Knowles, K., McKinney, T., Mizen, A. & Purcell, C., 18 Oct 2024, In: PLoS ONE. 19, 10, 16 p., e0311498.

Research output: Contribution to journal › Article › peer-review

Value of improving patient safety: Health-economic considerations for Rapid Response Systems – a Rapid Review of the Literature and Expert Round Table

Subbe, C., Hughes, D., Lewis, S., Holmes, E., Kalkman, C. J., So, R. K., Tranka, S. & Welch, J., 17 Apr 2023, In: BMJ Open. 13, 4, e065819.

Research output: Contribution to journal › Article › peer-review

Valuing pharmacogenetic testing services: A comparison of patients' and health care professionals' preferences

Holmes, E. A., Payne, K., Fargher, E. A., Roberts, S., Tricker, K., Elliott, R. A., Ratcliffe, J. & Newman, W., 1 Jan 2011, In: Value in Health. 14, 1, p. 121-134

Research output: Contribution to journal › Article › peer-review

WASh multicentre randomised controlled trial: water-assisted sigmoidoscopy in English NHS bowel scope screening

Rutter, M., Evans, R., Hoare, Z., von Wagner, C., Deane, J., Esmally, S., Larkin, T., Edwards, R. T., Yeo, S. T., Spencer, L., Holmes, E., Saunders, B., Rees, C., Tsiamoulos, Z. & Beintaris, I., 7 Apr 2021, In: GUT . 70, 5, p. 845–852 8 p.

Research output: Contribution to journal › Article › peer-review

What influences persistence with medicines? A multinational discrete choice experiment of 2549 patients

Holmes, E. A., Morrison, V. L. & Hughes, D., Aug 2016, In: British Journal of Clinical Pharmacology. 82, 2, p. 522-531

Research output: Contribution to journal › Article › peer-review

What really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK

Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Jun 2019, In: Epilepsy and Behavior. 95, p. 181-191

Research output: Contribution to journal › Article › peer-review

Women's experience of commercial weight-loss programmes

Holmes, E. A., Wickett, H. & Fargher, E. A., 1 Oct 2010, In: Practice Nursing. 21, 10, p. 252-259

Research output: Contribution to journal › Article › peer-review

Involving colleagues can be challenging

Fargher , E. & Hughes, D., 2 Apr 2011, In: Pharmaceutical Journal. 286, p. 404

Research output: Contribution to journal › Letter › peer-review

Research Governance: What is reasonable protection?

Payne, K., Fargher, E., Tricker, K., Newman, W., Qasim, F., Poulton, K., Andrews, J., Houston, J., Elliott, R., Elles, R., Ray, D., Shaffer, J., Griffiths, C., Bruce, I., Roberts, S. A. & Ollier, W., 2005, In: BMJ. 330, p. 847

Research output: Contribution to journal › Letter › peer-review

Challenges for economic evaluation of strategies to contain antimicrobial resistance

Holmes, E. & Hughes, D., 27 Sept 2019, In: Antibiotics. 8, 4, 8 p., 166.

Research output: Contribution to journal › Comment/debate › peer-review

Patient preferences for outcomes in clinical trials: implications for medicines optimization

Holmes, E., Marson, A. G. & Hughes, D., 8 May 2017, In: Trials. 18 (Suppl 1), O18, p. 192 1 p.

Research output: Contribution to journal › Meeting Abstract › peer-review