Bangor University

  1. Published

    The pharmacokinetic profile of Warfarn: a systematic review

    Hughes, D., Al-Zubiedi S.*, N. V., Hughes D.A., N. V. & Pirmohamed, M., 1 Dec 2007.

    Research output: Contribution to conferencePaper

  2. Published

    Economic evaluation of infliximab and adalimumab for Crohn's disease.

    Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  3. Published

    Medicines concordance and game theory.

    Hughes, D. & Hughes, D. A., 1 Oct 2008, In: British Journal of Clinical Pharmacology. 66, 4, p. 577

    Research output: Contribution to journalArticlepeer-review

  4. Published

    Molecular phylogeny supports division of the 'cosmopolitan' taxon Celleporella (Bryozoa; Cheilostomata) into four major clades.

    Hughes, R. N., Gomez, A., Wright, P. J., Moyano, H. I., Cancino, J. M., Carvalho, G. R. & Lunt, D. H., 1 Jan 2008, In: Molecular Phylogenetics and Evolution. 46, 1, p. 369-374

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

    Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Health utilities and costs for neuromyelitis optica spectrum disorder

    Hughes, D., Bourke, S., Jones, A., Bhatt, R., Huda, S., Mutch, K. & Jacob, A., 2022, In: Orphanet Journal of Rare Diseases. 17, 11 p., 159.

    Research output: Contribution to journalArticlepeer-review

  7. Published

    Habitat suitability modelling for an integrated multi-trophic aquaculture (IMTA) system along Europe's Atlantic coast

    Hughes, C. & King, J., 1 Oct 2023, In: Ecological Modelling. 484, 110459.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Examining relationships between adverse childhood experiences and coping during the cost-of-living crisis using a national cross-sectional survey in Wales, UK

    Hughes, K., Bellis, M., Cresswell, K., Hill, R., Ford, K. & Hopkins, J., 2 May 2024, In: BMJ Open. 14, 5, p. e081924

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Impact of relaxing Covid-19 social distancing measures on rural North Wales: a simulation analysis

    Hughes, R. P. & Hughes, D., 14 Dec 2020, In: Frontiers in Public Health. 8, 562473.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Changing depocentre environments of Palaeolake Olduvai and carbonates as marker horizons for hiatuses and lake-level extremes

    Hughes, T., Stanistreet, I., Doyle, C., Rushworth, E., Stollhofen, H., Toth, N., Schick, K. & Njau, J., 15 Dec 2020, In: Palaeogeography, Palaeoclimatology, Palaeoecology. 560, 110032.

    Research output: Contribution to journalArticlepeer-review

  11. Published
  12. Published

    Sexual behaviour among casual workers in an international nightlife resort: a case control study

    Hughes, K. & Bellis, M. A., 21 Feb 2006, In: BMC Public Health. 6, p. 39

    Research output: Contribution to journalArticlepeer-review

  13. Published

    Smoking behaviours, access to cigarettes and relationships with alcohol in 15- and 16-year-old schoolchildren

    Hughes, S. K., Hughes, K., Atkinson, A. M., Bellis, M. A. & Smallthwaite, L., Feb 2011, In: European Journal of Public Health. 21, 1, p. 8-14 7 p.

    Research output: Contribution to journalArticlepeer-review

  14. Published

    Welsh Literary Modernism, Lynette Roberts and David Jones: "unearthing a huge and very important culture"

    Hughes, D., 2 Apr 2019, Locating Lynette Roberts: Always observant and slightly obscure. McAvoy, S. (ed.). University of Wales Press, Cardiff, (Writing Wales in English).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  15. Published

    The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis

    Hughes, K., Bellis, M., Hardcastle, K., Sethi, D., Butchart, A., Mikton, C., Jones, L. & Dunne, M., Aug 2017, In: The Lancet. 2, 8, p. e356-e366

    Research output: Contribution to journalArticlepeer-review

  16. Published

    Impact of the abolition of the prescription charge in Wales.

    Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  17. Published

    Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

    Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

    Research output: Contribution to conferencePaper

  18. Published

    Optical control of dissipative quantum phase space dynamics.

    Hughes, K. H., Hywel. M.*, N. V., Lasorne, B. (ed.) & Worth, G. A. (ed.), 1 Jan 2006, Coherent Control of Molecules. 2006 ed. CCP, Daresbury, p. 28-33

    Research output: Chapter in Book/Report/Conference proceedingChapter

  19. Published

    Economic evaluation of a behavior-modifying intervention to enhance antiepileptic drug adherence

    Hughes, D., Plumpton, C. O., Brown, I., Reuber, M., Marson, A. G. & Hughes, D. A., 26 Mar 2015, In: Epilepsy and Behavior. 45, p. 180-186

    Research output: Contribution to journalArticlepeer-review

  20. Published

    The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies.

    Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

    Research output: Book/ReportCommissioned report

  21. Published

    Impact of non-compliance on the cost-effectiveness of pharmaceuticals

    Hughes, D. & Hughes, D. A., 1 Nov 2002.

    Research output: Contribution to conferencePaper

  22. Published

    Current international research into cellulosic fibres and composites

    Hughes, J. M., Eichhorn, S. J., Baillie, C. A., Zafeiropoulos, N., Mwaikambo, L. Y., Ansell, M. P., Dufresne, A., Entwistle, K. M., Herrera-Franco, P. J., Escamilla, G. C., Groom, L., Hughes, M., Hill, C., Rials, T. G. & Wild, P. M., 1 May 2001, In: Journal of Materials Science. 36, 9, p. 2107-2131

    Research output: Contribution to journalArticlepeer-review

  23. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Anidulafungin (Ecalta) for the treatment of invasive candidiasis in adult non-neutropenic patients.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

    Research output: Book/ReportCommissioned report

  24. Published

    The all wales medicines strategy group: assessments and appraisals

    Hughes, D. & Hughes, D. A., 1 Nov 2008.

    Research output: Contribution to conferencePaper

  25. Published

    The Experimental Analysis of Behaviour Group, London April 6th – 8th 2009, Programme of abstracts

    Hughes, J. C., Beverley, M., Beverley, M. (ed.) & Hughes, J. C. (ed.), 1 Jan 2009, In: European Journal of Behavior Analysis. 10, 2, p. 297-314

    Research output: Contribution to journalArticlepeer-review

  26. Published

    Adverse drug reactions: analysis by regulatory authorities and by economists

    Hughes, D. & Hughes, D. A., 1 Apr 2007.

    Research output: Contribution to conferencePaper

  27. Published

    Taking Fluency Based Instructional and Precision Teaching into main stream schools: Some preliminary studies.

    Hughes, E., Hughes, J. C., Whitehead, J. & Beverley, M., 1 Jan 2002.

    Research output: Contribution to conferencePaper

  28. Published

    A hybrid hydrodynamic-liouvillian approach to mixed quantum-classical dynamics: application to tunneling in a double well

    Hughes, K. H., Parry, S. M., Parlant, G. & Burghardt, I., 1 Aug 2007, In: Journal of Physical Chemistry A. 111, 41, p. 10269-10283

    Research output: Contribution to journalArticlepeer-review

  29. Published

    Systematic review of follow-up of cancer in primary care verses secondary care: findings for breast and lung cancer

    Hughes, D., Lewis, R., Neal, R. D., France, B., Williams, N. H., Wilkinson, C., Russell, I. T., Russell, D., Hughes, D. A., Stuart, N. S. & Weller, D., 1 Mar 2007.

    Research output: Contribution to conferencePaper

  30. Published

    An agenda for UK clinical pharmacology Pharmacoeconomics

    Hughes, D. & Hughes, D. A., 1 Jun 2012, In: British Journal of Clinical Pharmacology. 73, 6, p. 968-972

    Research output: Contribution to journalArticlepeer-review

  31. Published

    Impact of the abolition of the prescription charge in Wales.

    Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009, p. O41.

    Research output: Contribution to conferencePaper

  32. Published

    A Global Survey of Antibiotic Leftovers in the Outpatient Setting.

    Hughes, D., Kardas, P., Pechere, J. C., Hughes, D. A. & Cornaglia, G., 1 Dec 2007, In: International Journal of Antimicrobial Agents. 30, 6, p. 530-536

    Research output: Contribution to journalArticlepeer-review

  33. Published

    Introduction to pharmaeconomics

    Hughes, D. & Hughes, D. A., 1 Jul 2004.

    Research output: Contribution to conferencePaper

  34. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Rufinamide (Inovelon) for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS).

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  35. Published

    Abolition of prescription charges in Wales: the impact on medicines use in those who used to pay

    Hughes, D., Groves, S., Cohen, D., Alam, M. F., Dunstan, F. D., Routledge, P. A., Hughes, D. A. & Myles, S., 1 Dec 2010, In: International Journal of Pharmacy Practice. 18, 6, p. 332-340

    Research output: Contribution to journalArticlepeer-review

  36. Published

    Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

    Hughes, D., 1 Mar 2007.

    Research output: Contribution to conferencePaper

  37. Published

    NICE and new: appraising innovation.

    Hughes, D., Ferner, R. E., Hughes, D. A. & Aronson, J. K., 5 Jan 2010, In: British Medical Journal. 340, p. b5493

    Research output: Contribution to journalArticlepeer-review

  38. Published

    Using precision teaching to increase the fluency of word reading with problem readers.

    Hughes, J. C., Beverley, M. & Whitehead, J., 1 Jan 2007, In: European Journal of Behavior Analysis. 8, 2, p. 221-238

    Research output: Contribution to journalArticlepeer-review

  39. Published

    A single centre open phase IV study to evaluate the safety and tolerability of chlorproguanil-dapsone when dosed by defined height bands

    Hughes, D., Makanga, M., Winstanley, P. & Hughes, D. A., 1 Nov 2004.

    Research output: Contribution to conferencePaper

  40. Published

    Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

    Hughes, D. & Hughes, D. A., 1 May 2007.

    Research output: Contribution to conferencePaper

  41. Published

    The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies

    Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Nov 2000.

    Research output: Contribution to conferencePaper

  42. Published

    From efficacy to effectiveness and cost-effectiveness: modelling possibilities

    Hughes, D. & Hughes, D. A., 1 Nov 2004.

    Research output: Contribution to conferencePaper

  43. Published

    The Experimental Analysis of Behaviour Group, UK and Europe.

    Hughes, J. C., 1 Jan 2007, In: European Journal of Behavior Analysis. 8, 2, p. 105-107

    Research output: Contribution to journalArticlepeer-review

  44. Published

    Pharmacoeconomics in Wales: functions of the all Wales medicines strategy group

    Hughes, D. & Hughes, D. A., 1 Apr 2004.

    Research output: Contribution to conferencePaper

  45. Published

    Public health interventions to promote mental well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

    Hughes, D., Windle, G., Hughes, D. A., Linck, P., Morgan, R., Burholt, V., Edwards, R. T., Reeves, C., Yeo, S. T., Woods, R. T. & Russell, I. T., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  46. Published

    Prescription fee exemption research study

    Hughes, D., Myles, S., Hughes, D. A., Routledge, P. & Wales, D. F., 1 Jun 2006.

    Research output: Contribution to conferencePaper

  47. Published

    Reimbursement Decisions of the All Wales Medicines Strategy Group

    Hughes, D., Linley, W. G. & Hughes, D. A., 1 Sept 2012, In: PharmoEconomics. 30, 9, p. 779-794

    Research output: Contribution to journalArticlepeer-review

  48. Published

    The effects of megafaunal burrows on radiotracer profiles and organic composition in deep sea sediments:preliminary results from two sites in the bathyal north-east Atlantic.

    Hughes, D. J., Brown, L., Cook, G. T., Cowie, G., Gage, J. D., Good, E., Kennedy, H. A., MacKenzie, A. B., Papadimitriou, S., Shimmield, G. B., Thomson, J. & Williams, M., 1 Jan 2005, In: Deep Sea Research Part I: Oceanographic Research Papers. 52, 1, p. 1-13

    Research output: Contribution to journalArticlepeer-review

  49. Published

    Adverse drug reactions in economic evaluations

    Hughes, D. & Hughes, D. A., 1 Mar 2007.

    Research output: Contribution to conferencePaper

  50. Published

    Quantitative risk-benefit analysis

    Hughes, D. & Hughes, D. A., 1 May 2007.

    Research output: Contribution to conferencePaper

  51. Published

    Economic considerations for market access of new health technologies: A case study of pharmacogenetic testing

    Hughes, D. & Hughes, D. A., 1 Feb 2008.

    Research output: Contribution to conferencePaper

  52. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Tipranavir (Aptivus).

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  53. Published

    Training and certification of behaviour analysts in Europe: Past, present and future challenges.

    Hughes, J. C. & Shook, G. L., 1 Jan 2007, In: European Journal of Behavior Analysis. 8, 2, p. 239-249

    Research output: Contribution to journalArticlepeer-review

  54. Published

    Predicting "real world" effectiveness by integrating adherence with pharmacodynamic modelling.

    Hughes, D., Hughes, D. A. & Walley, T., 1 Jul 2003, In: Clinical Pharmacology and Therapeutics. 74, 1, p. 1-8

    Research output: Contribution to journalArticlepeer-review

  55. Published

    Archaeoleg a llenyddiaeth trioedd dirgel y gorllewin

    Hughes, L. A., Ahronson, K. & Ahronson, L. A., 1 Apr 2013, In: Y Traethodydd. 168, 705, p. 97-119

    Research output: Contribution to journalArticlepeer-review

  56. Published

    Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment

    Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 May 2007.

    Research output: Contribution to conferencePaper

  57. Published

    Policy on ultra-orphan drugs.

    Hughes, D. & Hughes, D. A., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  58. Published

    Is exercise effective in promoting mental well-being in older age? A systematic review.

    Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Aug 2010, In: Aging and Mental Health. 14, 6, p. 652-669

    Research output: Contribution to journalArticlepeer-review

  59. Published

    Shore crabs are able to transfer learned handling skills to novel prey

    Hughes, R. N. & O'Brien, N., 1 Apr 2001, In: Animal Behaviour. 61, 4, p. 711-714

    Research output: Contribution to journalArticlepeer-review

  60. Published

    Improving Outcomes for People with Brain and Other CNS Tumours: Analysis of the Potential Economic Impact of the Guidance.

    Hughes, D., Linck, P., Priedane, E., Hughes, D. A. & Edwards, R. T., 1 Jan 2006, 2006 ed. Unknown.

    Research output: Book/ReportCommissioned report

  61. E-pub ahead of print

    Barosensory vessel mechanics and the vascular sympathetic baroreflex: Impact on blood pressure homeostasis

    Hughes, G., Moore, J. & Lord, R., 9 Apr 2023, (E-pub ahead of print) In: Experimental Physiology.

    Research output: Contribution to journalReview articlepeer-review

  62. Published

    Health and financial costs of adverse childhood experiences in 28 European countries: a systematic review and meta-analysis

    Hughes, K., Ford, K., Bellis, M., Glendinning, F., Harrison, E. & Passmore, J., 1 Nov 2021, In: Lancet Public Health. 6, 11, p. e848-e857

    Research output: Contribution to journalArticlepeer-review

  63. Published

    The Effect of Trans-urethral Resection of the Bladder Tumour (TURBT) on Routine Haematological and Biochemical Blood Tests: A Clinical-pilot Observational Study

    Hughes, S. F., Lamb, R. M., Moyes, A., Ella-Tongwiis, P., Gill, A., Duckett, A. & Shergill, I., 1 Dec 2020, In: International Journal of Biomedical Science. 16, 4, p. 68-74

    Research output: Contribution to journalArticlepeer-review

  64. Published

    Drinking behaviours and blood alcohol concentration in four European drinking environments: a cross-sectional study

    Hughes, K., Quigg, Z., Bellis, M. A., van Hasselt, N., Calafat, A., Kosir, M., Juan, M., Duch, M. & Voorham, L., 12 Dec 2011, In: BMC Public Health. 11, p. 918

    Research output: Contribution to journalArticlepeer-review

  65. Published

    (Lynette writing about) Nesta: Recollection, Reclamation and Reconstruction in Lynette Roberts's Lost Novel

    Hughes, D., 20 Dec 2018, In: International Journal of Welsh Writing in English. 5, 2

    Research output: Contribution to journalArticlepeer-review

  66. Published

    Incorporating measures of compliance and persistence in pharmacoeconomic evaluations

    Hughes, D., Hughes, D. A. & Cowell, W., 1 Nov 2005.

    Research output: Contribution to conferencePaper

  67. Published

    Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.

    Hughes, D., Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., Van Eker, D., Stevens, L., Hawkins, K., Toh, C. H., Kamali, F., Daly, A. K., Fitzmaurice, D., Coffey, A., Williamson, P. R., Park, B. K., Deloukas, P. & Pirmohamed, M., 1 Oct 2009, In: Pharmacogenetics and Genomics. 19, 10, p. 800-812

    Research output: Contribution to journalArticlepeer-review

  68. Published

    From efficacy to cost-effectiveness: accounting for non-compliance in pharmacoeconomics

    Hughes, D. & Hughes, D. A., 1 May 2002.

    Research output: Contribution to conferencePaper

  69. Published

    Costs of Medication Nonadherence in Patients with Diabetes Mellitus: A Systematic Review and Critical Analysis of the Literature.

    Hughes, D., Salas, M., Hughes, D. A., Zuluaga, A., Vardeva, K. & Lebmeier, M., 1 Sept 2009, In: Value in Health. 12, 6, p. 915-922

    Research output: Contribution to journalArticlepeer-review

  70. Published

    Internationalisation of cost-effectiveness model for on-demand use of proton pump inhibitors - Sweden.

    Hughes, D. & Hughes, D. A., 1 Jan 2005, 2005 ed. Unknown.

    Research output: Book/ReportCommissioned report

  71. Published

    Approaches to pharmacoeconomic analysis

    Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 101-126

    Research output: Chapter in Book/Report/Conference proceedingChapter

  72. Published

    Patient compliance and pharmacoeconomics

    Hughes, D. & Hughes, D. A., 1 Oct 2001.

    Research output: Contribution to conferencePaper

  73. Published

    Adverse drug reactions in economic evaluations

    Hughes, D. & Hughes, D. A., 1 Jul 2007.

    Research output: Contribution to conferencePaper

  74. Published

    Impact of non-compliance on the cost-effectiveness of statin therapy

    Hughes, D., Hughes, D. A. & Bagust, A., 1 Sept 2001, In: Value in Health. 4, 6, p. 489

    Research output: Contribution to journalArticlepeer-review

  75. Published

    Transcriptomics and in vivo tests reveal novel mechanisms underlying endocrine disruption in an ecological sentinel, Nucella lapillus

    Hughes, R. N., Pascoal, S., Carvalho, G. R., Vasieva, O., Hughes, R., Cossins, A., Fang, Y., Ashelford, K., Olohan, L., Barroso, C., Mendo, S. & Creer, S., 1 Mar 2013, In: Molecular Ecology. 22, 6, p. 1589-1608

    Research output: Contribution to journalArticlepeer-review

  76. Published

    Economic evaluation of steroid injections (methylprednisolone) in the treatment of Morton's neuroma: patient-blind randomised trial

    Hughes, D., Thomson, C., Beggs, I., Martin, D., McCaldin, D., Russell, D., Edwards, R. T., Hughes, D. A., Yeo, S. T., Russell, I. T. & Gibson, T. N., 1 Mar 2007.

    Research output: Contribution to conferencePaper

  77. Published

    Extended hydrodynamic approach to quantum-classical nonequilibrium evolution. II. Application to nonpolar solvation

    Hughes, K. H., Baxter, S., Bousquet, D., Ramanathan, P. & Burghardt, I., 7 Jan 2012, In: Journal of Chemical Physics. 136, 1, 014102.

    Research output: Contribution to journalArticlepeer-review

  78. Published

    Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Nov 2003.

    Research output: Contribution to conferencePaper

  79. Published

    The relationship between sensory quality and volatile compounds in raw juice processed from elderberries (Sambucus nigra L.)

    Hughes, J. M., Kaack, K., Christensen, L. P., Hughes, M. & Eder, R., 1 Aug 2005, In: European Food Research and Technology. 221, 3-4, p. 244-254

    Research output: Contribution to journalArticlepeer-review

  80. Published

    Assessment, Determinants & Economics of Medication Compliance & Persistence Forum.

    Hughes, D., Hughes, D. A., Gwadry-Sridhar, F. & Manias, E., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  81. Published

    A review of economic models for second-line chemotherapy in the management of advanced, metastatic breast cancer.

    Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

    Research output: Book/ReportCommissioned report

  82. Published

    Drug compliance and pharmaceconomics

    Hughes, D. & Hughes, D. A., 1 Dec 2003.

    Research output: Contribution to conferencePaper

  83. Published

    Costs of non-compliance to antipsychotic medications among patients with schizophrenia.

    Hughes, D., Hughes, D. A., Salas, M., Zuluaga, A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 May 2008.

    Research output: Contribution to conferencePaper

  84. Published

    Conducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches

    Hughes, D., Charles, J. M., Dawoud, D. M., Edwards, R. T., Holmes, E. A., Jones, C. L., Parham, P., Plumpton, C., Ridyard, C. O., Lloyd-Williams, H., Wood, E. M. & Yeo, S., May 2016, In: Pharmacoeconomics. 34, 5, p. 447-461

    Research output: Contribution to journalArticlepeer-review

  85. Published

    Engaging with the MRC Methodology Hubs – NWHTMR.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  86. Published

    Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment

    Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 Jan 2007, In: Value in Health. 10, 3, p. A23

    Research output: Contribution to journalArticlepeer-review

  87. Published

    Cost-utility analysis of on demand rabeprazole and esomeprazole for symptomatic gastro oesophageal reflux disease

    Hughes, D., Hughes, D. A. & Dubois, D., 1 Nov 2003, In: Value in Health. 6, 6, p. 613

    Research output: Contribution to journalArticlepeer-review

  88. Published

    Pharmacoeconomic models that incorporate non-compliance

    Hughes, D. & Hughes, D. A., 1 Jul 2004.

    Research output: Contribution to conferencePaper

  89. Published

    Generic and therapeutic substitutions in the UK: are they a good thing?

    Hughes, D., Duerden, M. G. & Hughes, D. A., 1 Sept 2010, In: British Journal of Clinical Pharmacology. 70, 3, p. 335-341

    Research output: Contribution to journalArticlepeer-review

  90. Published

    Cloning and characterization of the pnb genes, encoding enzymes for 4-nitrobenzoate catabolism in Pseudomonas putida TW3.

    Hughes, M. A. & Williams, P. A., 1 Feb 2001, In: Journal of Bacteriology. 183, 4, p. 1225-1232

    Research output: Contribution to journalArticlepeer-review

  91. Published

    Effects of the abolition of prescription charges in Wales: A preliminary analysis

    Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

    Research output: Contribution to conferencePaper

  92. Published

    New drugs for old: disinvestment and NICE.

    Hughes, D., Hughes, D. A. & Ferner, R. E., 25 Feb 2010, In: British Medical Journal. 340, p. c572

    Research output: Contribution to journalArticlepeer-review

  93. Published

    All Wales Medicines Strategy Group Final Assessment Report – Agalsidase alfa (Replagal)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  94. Published
  95. Published

    Non-Markovian reduced dynamics of ultrafast charge transfer at an oligothiophene–fullerene heterojunction

    Hughes, K. H., Cahier, B., Martinazzo, R., Tamura, H. & Burghardt, I., 9 Jul 2014, In: Chemical Physics. 442, p. 111-118

    Research output: Contribution to journalArticlepeer-review

  96. Published

    The cost-effectiveness of biological therapies for Crohn's disease: Markov cohort analyses incorporating UK patient-level cost data

    Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Mar 2008.

    Research output: Contribution to conferencePaper

  97. Published

    Empirical analysis of the relationship between dose and duration of drug action

    Hughes, D. & Hughes, D. A., 1 Jun 2005.

    Research output: Contribution to conferencePaper

  98. Published

    Boltzmann wavepacket dynamics on periodic molecular potential functions.

    Hughes, K. H. & Macdonald, J. N., 1 Oct 2000, In: Physical Chemistry Chemical Physics. 2, 19, p. 4267-4273

    Research output: Contribution to journalArticlepeer-review

  99. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Topotecan (Hycamtin®) for Small Cell Lung Carcinoma.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  100. Published

    Orphan drug treatments: economic considerations

    Hughes, D. & Hughes, D. A., 1 Nov 2007.

    Research output: Contribution to conferencePaper

  101. Published

    HLA-B*5701 and abacavir hypersensitivity - Reply.

    Hughes, D., Hughes, D. A., Park, B. K. & Pirmohamed, M., 1 Nov 2004, In: Pharmacogenetics. 14, 11, p. 784

    Research output: Contribution to journalArticlepeer-review

  102. Published

    Does Electronic Monitoring Influence Adherence to Medication? Randomized Controlled Trial of Measurement Reactivity

    Hughes, D., Sutton, S., Kinmonth, A. L., Hardeman, W., Hughes, D. A., Boase, S., Prevost, T., Kellar, I., Graffy, J., Griffin, S. & Farmer, A., 1 Dec 2014, In: Annals of Behavioral Medicine. 48, 3, p. 293-299

    Research output: Contribution to journalArticlepeer-review

  103. Published

    The population pharmacokinetics of lapdap

    Hughes, D., Ward, S., Simpson, J., Aarons, L., Szwandt, S. & Hughes, D. A., 1 Nov 2002.

    Research output: Contribution to conferencePaper

  104. Published

    Comparative Effectiveness of Dabigatran, Rivaroxaban, Apixaban, and Warfarin in the Management of Patients With Nonvalvular Atrial Fibrillation

    Hughes, D., Pink, J., Pirmohamed, M. & Hughes, D. A., 25 Apr 2013, In: Clinical Pharmacology and Therapeutics.

    Research output: Contribution to journalArticlepeer-review

  105. Published

    Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam

    Hughes, D., Nov 2020, In: British Journal of Pharmacology. 177, 21, p. 4975-4989 15 p.

    Research output: Contribution to journalArticlepeer-review

  106. Published

    A new location for the rare French endemic woodlouse Alloschizidium pruvoti (Racovitza, 1907) (Oniscidea: Armadillidiidae)

    Hughes, T., 2020, In: Bulletin of the British Myriapod and Isopod Group. 32, p. 68-72 5 p.

    Research output: Contribution to journalArticlepeer-review

  107. Published

    The role of specific biomarkers, as predictors of post-operative complications following flexible ureterorenoscopy (FURS), for the treatment of kidney stones: a single-centre observational clinical pilot-study in 37 patients.

    Hughes, S. F., Moyes, A., Lamb, R. M., Ella-Tongwiis, P., Bell, C., Moussa, A. & Shergill, I., Aug 2020, In: BMC Urology. 14, 20, 122.

    Research output: Contribution to journalArticlepeer-review

  108. Published

    The value of hospices in North Wales- A collaboration between academia and third sector organisations

    Hughes, N., Noyes, J., Jones, C. & Pritchard, T., 26 Nov 2018, In: BMJ Supportive and Palliative Care. 8, Supp 2, p. A90

    Research output: Contribution to journalConference articlepeer-review

  109. Published

    Moral economy, solidarity and labour process struggle in Irish public transport

    Hughes, E., Dobbins, T. & Merkl-Davies, D., 20 Dec 2019, In: Economic and Industrial Democracy.

    Research output: Contribution to journalArticlepeer-review

  110. Published
  111. Published

    Predictors of violence in young tourists: a comparative study of British, German and Spanish holidaymakers

    Hughes, K., Bellis, M. A., Calafat, A., Juan, M., Schnitzer, S. & Anderson, Z., Dec 2008, In: European Journal of Public Health. 18, 6, p. 569-74 6 p.

    Research output: Contribution to journalArticlepeer-review

  112. Published

    Relationships between adverse childhood experiences and adult mental well-being: results from an English national household survey

    Hughes, K., Lowey, H., Quigg, Z. & Bellis, M. A., 3 Mar 2016, In: BMC Public Health. 16, p. 222

    Research output: Contribution to journalArticlepeer-review

  113. Published

    Ffynonellau gwydnwch a’u cysylltiadau lliniarol gyda’r niwed sy’n cael ei achosi gan brofiadau niweidiol yn ystod plentyndod: Adroddiad 1: Salwch meddwl

    Hughes, K., Ford, K., Davies, A., Homolova, L. & Bellis, M., 18 Jan 2018, Public Health Wales NHS Trust. 60 p.

    Research output: Book/ReportOther reportpeer-review

  114. Published

    Rapid, Semi-Automated Fractionation of Freshwater Dissolved Organic Carbon Using DAX 8 (XAD 8) and XAD 4 Resins in Tandem

    Hughes, D., Holliman, P., Jones, T., Jones, T., Butler, A. J. & Freeman, C., 22 Nov 2016, In: Natural Science. 8, 11, p. 487-498

    Research output: Contribution to journalArticlepeer-review

  115. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Clofarabine (Evoltra)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  116. Published

    Two intertidal fish species use visual association learning to track the status of food patches in a radial maze

    Hughes, R. N. & Blight, C. M., 1 Mar 2000, In: Animal Behaviour. 59, 3, p. 613-621

    Research output: Contribution to journalArticlepeer-review

  117. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Darunavir (Prezista)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  118. Published

    Impact of the abolition of prescription charges in Wales: a multi-level modelling approach with application to time series dispensed rate data

    Hughes, D., Alam, F., Myles, S., Hughes, D. A., Dunstan, F., Routledge, P. & Cohen, D., 1 Sept 2007.

    Research output: Contribution to conferencePaper

  119. Published

    Evaluation of a consultant audit and feedback programme to improve the quality of antimicrobial prescribing in acute medical admissions

    Hughes, D., Roberts, E., Dawoud, D. M., Hughes, D. A. & Cefai, C., 1 Oct 2015, In: International Journal of Pharmacy Practice. 23, 5, p. 333-339

    Research output: Contribution to journalArticlepeer-review

  120. Published

    Pragmatic trials - design features and implications for clinical decision making

    Hughes, D., Urdahl, H., Hughes, D. A. & Freemantle, N., 1 Aug 2000.

    Research output: Contribution to conferencePaper

  121. Published

    Impact of pharmacogenetics on the costs of managing adverse events with warfarin: A prospective analysis.

    Hughes, D., Hughes, D. A., Al-Zubiedi, S., Hanson, A., Jorgensen, A. & Pirmohamed, M., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  122. Published

    Wavepacket dynamics on arbitrary Lagrangian-Eulerian grids: application to an Eckart barrier

    Hughes, K. H. & Wyatt, R. E., 1 Jan 2003, In: Physical Chemistry Chemical Physics. 5, 18, p. 3905-3910

    Research output: Contribution to journalArticlepeer-review

  123. Published

    Societal views on NICE, cancer drugs fund and value-based pricing criteria for prioritising medicines: a cross-sectional survey of 4118 adults in Great Britain

    Hughes, D., Linley, W. G. & Hughes, D. A., 1 Aug 2013, In: Health Economics. 22, 8, p. 948-964

    Research output: Contribution to journalArticlepeer-review

  124. Published

    Falls and hip-fractures: A cost-effectiveness analysis of risk assessment and interventions for community-dwelling older people

    Hughes, D., Gwynne, D., Hughes, D. A. & Edwards, R. T., 1 Mar 2007.

    Research output: Contribution to conferencePaper

  125. Published

    Female investment is retarded pending reception of allosperm in a hermaphroditic colonial invertebrate.

    Hughes, R. N., Manriquez, P. H. & Bishop, J. D., 1 Nov 2002, In: Proceedings of the National Academy of Sciences of the USA. 99, 23, p. 14884-14886

    Research output: Contribution to journalArticlepeer-review

  126. Published

    Economic considerations for pharmacogenetic testing

    Hughes, D. & Hughes, D. A., 1 Jun 2008.

    Research output: Contribution to conferencePaper

  127. Published

    Stress promotes maleness in hermaphroditic modular animals.

    Hughes, R. N., Manriquez, P. H., Bishop, J. D. & Burrows, M. T., 1 Sept 2003, In: Proceedings of the National Academy of Sciences of the USA. 100, 18, p. 10326-10330

    Research output: Contribution to journalArticlepeer-review

  128. Published

    Non-compliance with antibiotic therapy for acute community infections: A global survey.

    Hughes, D., Pechere, J. C., Hughes, D. A., Kardas, P. & Cornaglia, G., 1 Mar 2007, In: International Journal of Antimicrobial Agents. 29, 3, p. 245-253

    Research output: Contribution to journalArticlepeer-review

  129. Published

    Accounting for non-compliance in pharmacoeconomic evaluations.

    Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 12, p. 1185-1197

    Research output: Contribution to journalArticlepeer-review

  130. Published

    Difficulties in separating hurricane induced effects from natural benthic succession: Hurricane Isabel, a case study from Eastern Virginia, USA.

    Hughes, C., Richardson, C. A., Luckenbach, M. & Seed, R., 30 Nov 2009, In: Estuarine, Coastal and Shelf Science. 85, 3, p. 377-386

    Research output: Contribution to journalArticlepeer-review

  131. Published

    Impact of non-compliance on the therapeutic coverage of oxybutynin – comparison of once- and twice-daily oral formulations.

    Hughes, D. & Hughes, D. A., 1 Jan 2002, 2002 ed. Unknown.

    Research output: Book/ReportCommissioned report

  132. Published

    An explanatory randomised controlled trial of a nurse-led, consultation-based intervention to support patients with adherence to taking glucose lowering medication for type 2 diabetes

    Hughes, D., Farmer, A., Hardeman, W., Hughes, D. A., Prevost, A. T., Kim, Y., Craven, A., Oke, J., Boase, S., Selwood, M., Kellar, I., Graffy, J., Griffin, S., Sutton, S. & Kinmonth, A. L., 5 Apr 2012, In: BMC Family Practice. 13, 30

    Research output: Contribution to journalArticlepeer-review

  133. Published

    Economic evaluations during early (Phase II) drug development: A role for clinical trial simulations.

    Hughes, D., Hughes, D. A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 11, p. 1069-1077

    Research output: Contribution to journalArticlepeer-review

  134. Published

    Biological agents for the management of Crohn's disease in adults: A systematic review, meta-analysis and multiples treatment comparison

    Hughes, D., Hughes, D. A., Kikuchi, T. & Bodger, K., 1 Jan 2007, In: Value in Health. 10, 3, p. A147

    Research output: Contribution to journalArticlepeer-review

  135. Published

    A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)

    Hughes, D., Ramanan, A., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., Hickey, H., Hughes, D. A., Jones, A., Woo, P., Edelsten, C., Beresford, M. W. & The SYCAMORE Trail Management Group, N. V., 9 Jan 2014, In: Trials. 15, 14

    Research output: Contribution to journalArticlepeer-review

  136. Published

    Defining rewardable innovation in drug therapy

    Hughes, D., Aronson, J. K., Ferner, R. E. & Hughes, D. A., 1 Apr 2012, In: Nature Reviews Drug Discovery. 11, p. 253-254

    Research output: Contribution to journalArticlepeer-review

  137. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Lenalidomide (Revlimid) for multiple myeloma.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  138. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Epoetin delta (Dynepo)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  139. Published

    Health economic aspects of patient non-compliance

    Hughes, D., Hughes, D. A., Davies, M. (ed.) & Kermani, F. (ed.), 1 Jan 2006, Patient Compliance: Sweetening the Pill. 2006 ed. Gower Publishing, p. 23-40

    Research output: Chapter in Book/Report/Conference proceedingChapter

  140. Published

    Adherence and variability in warfarin dose requirements: assessment in a prospective cohort

    Hughes, D., Jorgensen, A. L., Hughes, D. A., Hanson, A., van Eker, D., Toh, C. H., Pirmohamed, M. & Williamson, P. R., 1 Jan 2013, In: Pharmacogenomics. 14, 2, p. 151-163

    Research output: Contribution to journalArticlepeer-review

  141. Published

    Associations between e-cigarette access and smoking and drinking behaviours in teenagers

    Hughes, K., Bellis, M. A., Hardcastle, K. A., McHale, P., Bennett, A., Ireland, R. & Pike, K., 31 Mar 2015, In: BMC Public Health. 15, 244

    Research output: Contribution to journalArticlepeer-review

  142. Published

    Adherence with HAART: pharmacoeconomic considerations

    Hughes, D. & Hughes, D. A., 1 Jun 2007.

    Research output: Contribution to conferencePaper

  143. Published

    Warfarin pharmacogenetics: Economic considerations.

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Jan 2007, In: Pharmacoeconomics. 25, 11, p. 899-902

    Research output: Contribution to journalArticlepeer-review

  144. Published

    Current assessment of risk-benefit by regulators: Is it time to introduce decision analyses?

    Hughes, D., Hughes, D. A., Pirmohamed, M. & Bayoumi, A., 1 Aug 2007.

    Research output: Contribution to conferencePaper

  145. Published

    Patterns of self compatibility, inbreeding depression, outcrossing, and sex allocation in a marine bryozoan suggest the predominating influence of sperm competition.

    Hughes, R. N., Wright, P. J., Carvalho, G. R. & Hutchinson, W. F., 1 Nov 2009, In: Biological Journal of the Linnean Society. 98, 3, p. 519-531

    Research output: Contribution to journalArticlepeer-review

  146. Published

    Investigating factors influencing user choices to visit either general practioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment.

    Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  147. Published

    Improving Outcomes in Children and Young People with Cancer: Analysis of the Potential Economic Impact of the Guidance.

    Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2005, 2005 ed. Unknown.

    Research output: Book/ReportCommissioned report

  148. Published

    Methodological Issues in the literature on costs of non-compliance in chronic diseases.

    Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008, In: Value in Health. 11, 6, p. A571-A572

    Research output: Contribution to journalArticlepeer-review

  149. Published

    The effect of compliance upon clinical effectiveness of chlorproguanil-dapsone (CD) and artemether-lumefantrine (AL) when compared to sulfadoxine-pyrimethamine (SP) for the treatment of uncomplicated falcipaum malaria in Malawi - a randomised controlled trial

    Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Zijlstra, E., Hughes D.A., N. V., Molyneux M.E.*, N. V., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 1 Nov 2007.

    Research output: Contribution to conferencePaper

  150. Published

    Public funding of drugs for orphan diseases

    Hughes, D. & Hughes, D. A., 1 Jan 2006.

    Research output: Contribution to conferencePaper

  151. Published

    "Before I came to the hospice, I had nobody". A qualitative exploration of what patients, family-caregivers, clinicians and volunteers valued most about home, day therapy or inpatient hospice services

    Hughes, N. M., Noyes, J., Stringer, C. & Pritchard, T., 2024, In: Palliative Care and Social Practice . 18

    Research output: Contribution to journalArticlepeer-review

  152. Published
  153. Published
  154. Published

    Alcohol, nightlife and violence: the relative contributions of drinking before and during nights out to negative health and criminal justice outcomes

    Hughes, K., Anderson, Z., Morleo, M. & Bellis, M. A., Jan 2008, In: Addiction. 103, 1, p. 60-5 6 p.

    Research output: Contribution to journalArticlepeer-review

  155. Published

    Substance use, violence, and unintentional injury in young holidaymakers visiting Mediterranean destinations

    Hughes, K., Bellis, M. A., Calafat, A., Blay, N., Kokkevi, A., Boyiadji, G., Mendes, M. D. R. & Bajcàrova, L., 4 Mar 2011, In: Journal of Travel Medicine. 18, 2, p. 80-9 10 p.

    Research output: Contribution to journalArticlepeer-review

  156. Published

    NICE recommendations: why no disinvestment recommendations to offset investment decisions?

    Hughes, D., Tuersley, L. V., Hughes, D. A., Wood, E. M. & Tuersley, L., 19 May 2015, In: BMJ. 350

    Research output: Contribution to journalArticlepeer-review

  157. Published

    Cost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease

    Hughes, D. & Hughes, D. A., 1 Nov 2004, In: Value in Health. 7, 6, p. 753

    Research output: Contribution to journalArticlepeer-review

  158. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Buprenorphine/naloxone (Suboxone) as substitution treatment for opioid dependence.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  159. Published

    Accurate and practical dosing of African populations using a height, weight and age model designed for lapdap

    Hughes, D., Hughes, D. A. & Bagust, A., 1 Nov 2002.

    Research output: Contribution to conferencePaper

  160. Published

    Public funding of drugs for orphan diseases

    Hughes, D. & Hughes, D. A., 1 Nov 2005.

    Research output: Contribution to conferencePaper

  161. Published

    e-Viz: Towards an integrated framework for high performance visualization.

    Hughes, C. J., Riding, M., Wood, J., Brodlie, K., Chen, M., Chisnall, D. H., John, N. W., Jones, M. W. & Roard, N., 1 Jan 2005, p. 1026-1032.

    Research output: Contribution to conferencePaper

  162. Published
  163. Published

    Methodological issues in the literature on costs of non-compliance in chronic diseases

    Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008.

    Research output: Contribution to conferencePaper

  164. Published
  165. Published

    Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi.

    Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Hughes, D. A., Molyneux, M. E., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 26 Aug 2009, In: Malaria Journal. 8, p. 204

    Research output: Contribution to journalArticlepeer-review

  166. Published

    Impact of non-compliance on the clinical and cost-effectiveness of statins

    Hughes, D. & Hughes, D. A., 1 Nov 2001.

    Research output: Contribution to conferencePaper

  167. Published

    The fracture toughness of bast fibre reinforced polyester composites - Part 1 - Evaluation and analysis

    Hughes, J. M., Hill, C. & Hague, J. R., 1 Nov 2002, In: Journal of Materials Science. 37, 21, p. 4669-4676

    Research output: Contribution to journalArticlepeer-review

  168. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  169. Published

    Assessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients

    Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A171

    Research output: Contribution to journalArticlepeer-review

  170. Published

    Cisplatin plus vinorelbine or gemcitabine in patients with advanced non-small cell lung cancer: Pharmacoeconomic considerations.

    Hughes, D. & Hughes, D. A., 1 Jul 2005, In: European Journal of Cancer. 41, 11, p. 1655

    Research output: Contribution to journalArticlepeer-review

  171. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Trabectedin (Yondelis) for advanced soft tissue sarcoma.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  172. Published

    Cost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease.

    Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Feb 2005, In: Expert Review of Pharmacoeconomics and Outcomes Research. 5, 1, p. 29-38

    Research output: Contribution to journalArticlepeer-review

  173. Published

    Public meetings of the NICE appraisals committee

    Hughes, D. & Hughes, D. A., 1 Dec 2007.

    Research output: Contribution to conferencePaper

  174. Published

    Modelling changes in first line antimalarial therapy

    Hughes, D. & Hughes, D. A., 1 Sept 2003.

    Research output: Contribution to conferencePaper

  175. Published

    Estimating Drug Costs in Economic Evaluations in Ireland and the UK: An Analysis of Practice and Research Recommendations.

    Hughes, D., Hughes, D. A., Tilson, L. & Drummond, M. F., 1 May 2009, In: Pharmacoeconomics. 27, 8, p. 635-643

    Research output: Contribution to journalArticlepeer-review

  176. Published

    Plastic and Heritable Components of Phenotypic Variation in Nucella lapillus: An Assessment Using Reciprocal Transplant and Common Garden Experiments

    Hughes, R. N., Pascoal, S., Carvalho, G. R., Creer, S., Rock, J., Kawaii, K., Mendo, S. & Hughes, R., 27 Jan 2012, In: PLoS ONE. 7, 1, p. e30289

    Research output: Contribution to journalArticlepeer-review

  177. Published

    Abolition of prescription copayments in Wales: an observational study on dispensing rates.

    Hughes, D., Cohen, D., Alam, M. F., Dunstan, F. D., Myles, S., Hughes, D. A. & Routledge, P. A., 1 Aug 2010, In: Value in Health. 13, 5, p. 675-680

    Research output: Contribution to journalArticlepeer-review

  178. Published

    A systematic review of cost–effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives

    Hughes, D., Verhoef, T. I., Redekop, W. K., Darba, J., Geitona, M., Hughes, D. A., Siebert, U., de Boer, A., Maitland-van der Zee, A. H., Barallon, R., Briz, M., Daly, A., Haschke-Becher, E., Kamali, F., Kirchheiner, J., Manolopoulos, V. G., Pirmohamed, M., Rosendaal, F. R., van Schie, R. M. & Wadelius, M., 1 Jul 2010, In: Pharmacogenomics. 11, 7, p. 989-1002

    Research output: Contribution to journalArticlepeer-review

  179. Published

    A Risk–Benefit Assessment of Prasugrel, Clopidogrel, and Genotype-Guided Therapy in Patients Undergoing Percutaneous Coronary Intervention

    Hughes, D., Guzauskas, G. F., Hughes, D. A., Bradley, S. M. & Veenstra, D. L., 28 Mar 2012, In: Clinical Pharmacology and Therapeutics.

    Research output: Contribution to journalArticlepeer-review

  180. Published

    InK-Compact: In-Kernel Stream Compaction and Its Application to Multi-Kernel Data Visualization on General-Purpose GPUs

    Hughes, D. M., Lim, I. S., Jones, M., Knoll, A. & Spencer, B., 1 Sept 2013, In: Computer Graphics Forum. 32, 6, p. 178-188

    Research output: Contribution to journalArticlepeer-review

  181. Published

    Impact of the abolition of the prescription charge in Wales

    Hughes, D. & Hughes, D. A., 1 Nov 2008.

    Research output: Contribution to conferencePaper

  182. Published

    Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations.

    Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Nov 2007, In: Value in Health. 10, 6, p. 498-509

    Research output: Contribution to journalArticlepeer-review

  183. Published

    Statistical comments are unfounded.

    Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Mar 2008, In: Value in Health. 11, 2, p. 346

    Research output: Contribution to journalArticlepeer-review

  184. Published

    The cost-effectiveness of biological therapies for Crohn's disease: markov cohot analyses incorporating UK patient-level cost data

    Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 May 2008.

    Research output: Contribution to conferencePaper

  185. Published
  186. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Stiripentol (Diacomit) for use in conjunction with clobazam and valproate in patients with severe myoclonic epilepsy in infancy.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  187. Published

    The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol

    Hughes, D., Jenkinson, M. D., Gamble, C., Hartley, J. C., Hickey, H., Hughes, D. A., Blundell, M., Griffiths, M. J., Solomon, T. & Malluci, C. L., 3 Jan 2014, In: Trials. 15, 14

    Research output: Contribution to journalArticlepeer-review

  188. Published

    Improving Outcomes for People with Skin Tumours including Melanoma: Analysis of the Potential Economic Impact of the Guidance.

    Hughes, D., Linck, P., Hughes, D. A. & Edwards, R. T., 21 Feb 2006, Unknown.

    Research output: Book/ReportCommissioned report

  189. Published

    A feasibility study of auricular therapy and self-administered acupressure for insomnia following cancer treatment

    Hughes, J. G., Towler, P., Storey, L., Wheeler, S. L. & Molassiotis, A., Dec 2015, In: European Journal of Integrative Medicine. 7, 6, p. 623-627

    Research output: Contribution to journalArticlepeer-review

  190. Published

    Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Sept 2003.

    Research output: Contribution to conferencePaper

  191. Published

    Use of PK-PD modelling to predict the impact of non-compliance

    Hughes, D. & Hughes, D. A., 1 Nov 2003.

    Research output: Contribution to conferencePaper

  192. Published

    Multiple imputation of multiple multi-item scales when a full imputation model is infeasible

    Hughes, D., Plumpton, C. O., Morris, T., Hughes, D. A. & White, I. R., 26 Jan 2016, In: BMC Research Notes. 9, 45, p. 1-15

    Research output: Contribution to journalArticlepeer-review

  193. Published

    Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

    Hughes, D. & Hughes, D. A., 1 Jun 2003.

    Research output: Contribution to conferencePaper

  194. Published

    A potential method for discriminating between tissue from the European lobster (Homarus gammarus) and the American lobster (Homarus americanus).

    Hughes, G. & Beaumont, A. R., 1 Mar 2004, In: Crustaceana. 77, 3, p. 371-376

    Research output: Contribution to journalArticlepeer-review

  195. Published

    Quantum hydrodynamics for mixed states.

    Hughes, K. H., Parry, S. M., Burghardt, I., Shalashilin, D. V. (ed.) & De Miranda, M. P. (ed.), 1 Jan 2009, Multidimensional Quantum Mechanics with Trajectories. 2009 ed. CCP, Daresbury, p. 74-76

    Research output: Chapter in Book/Report/Conference proceedingChapter

  196. Published

    Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

    Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Aug 2007, In: Clinical Pharmacology and Therapeutics. 82, 2, p. 123-127

    Research output: Contribution to journalArticlepeer-review

  197. Published
  198. Published
  199. Published

    Shock wave lithotripsy, for the treatment of kidney stones, results in changes to routine blood tests and novel biomarkers: a prospective clinical pilot-study.

    Hughes, S. F., Jones, N., Thomas-Wright, S. J., Banwell, J., Moyes, A. & Shergill, I., 1 Jun 2020, In: European Journal of Medical Research. 1, 25, 18.

    Research output: Contribution to journalArticlepeer-review

  200. Published

    The role of phagocytic leukocytes following flexible ureterenoscopy, for the treatment of kidney stones: an observational, clinical pilots-study

    Hughes, S. F., Moyes, A., Lamb, R. M., Ella-Tongwiis, P., Snyper, N. Y. F. & Shergill, I., 11 Dec 2020, In: European Journal of Medical Research. 11, 25, 68.

    Research output: Contribution to journalLetterpeer-review

  201. Published

    Management of Patients Symptomatically Unresponsive to Levothyroxine: Natural Desiccated Thyroid Extract or the Combination of Levothyroxine and Liothyronine? A Research Priority

    Hughes, D., Livingston, M. & Heald, A., Sept 2020, In: Experimental and Clinical Endocrinology & Diabetes . 128, 9, p. 596-598

    Research output: Contribution to journalLetterpeer-review

  202. Published

    Health and financial burden of adverse childhood experiences in England and Wales: a combined primary data study of five surveys

    Hughes, K., Ford, K., Kadel, R., Sharp, C. & Bellis, M., 7 Jun 2020, In: BMJ Open. 10, 6, 9 p., e036374.

    Research output: Contribution to journalArticlepeer-review

  203. Published
  204. Published
  205. Published

    A Collaborative approach: Care staff and families working together to safeguard the quality of life of residents living with advanced dementia

    Hughes, S., Woods, R., Algar-Skaife, K., Jelley, H. & Jones, C., 13 May 2019, In: Journal of Central Nervous System Disease. 11, p. 1-9 9 p.

    Research output: Contribution to journalArticlepeer-review

  206. Published

    Sources of resilience and their moderating relationships with harms from adverse childhood experiences. Report 1: Mental illness

    Hughes, K., Ford, K., Davies, A., Homolova, L. & Bellis, M., 18 Jan 2018, Public Health Wales NHS Trust. 60 p.

    Research output: Book/ReportOther reportpeer-review

  207. Published

    Economics of pharmacogenetic guided treatments: Underwhelming or overstated?

    Hughes, D., May 2018, In: Clinical Pharmacology and Therapeutics. 103, 5, p. 749-751

    Research output: Contribution to journalArticlepeer-review

  208. Published

    Interventions to improve osteoporosis medication adherence and persistence: a systematic review and literature appraisal by the ISPOR Medication Adherence & Persistence Special Interest Group

    Hughes, D., Linck, P. G., Hiligsmann, M., Salas, M., Hughes, D. A., Manias, E., Gwadry-Sridhar, F. H., Linck, P. & Cowell, W., 1 Dec 2013, In: Osteoporosis International. 24, 12, p. 2907-2918

    Research output: Contribution to journalArticlepeer-review

  209. Published

    Public funding of drugs for orphan diseases

    Hughes, D. & Hughes, D. A., 1 Jul 2005.

    Research output: Contribution to conferencePaper

  210. Published

    Drugs for exceptionally rare diseases: do they deserve special status for funding?

    Hughes, D., Tunnage, B. & Yeo, S. T., 1 Nov 2005, In: QJM - An International Journal of Medicine. 98, 11, p. 829-836

    Research output: Contribution to journalArticlepeer-review

  211. Published

    Impact of the abolition of the prescription charge in Wales.

    Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  212. Published

    Adverse drug reactions in economic evaluations

    Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A109

    Research output: Contribution to journalArticlepeer-review

  213. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Emtricitabine/tenofovir DF (Truvada)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  214. Published

    A flexible infrastructure for delivering augmented reality enabled transcranial magnetic stimulation

    Hughes, C. J., Hughes, C. & John, N. W., 1 Jan 2006, p. 219-224.

    Research output: Contribution to conferencePaper

  215. Published

    The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

    Hughes, D., Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Jan 2012, In: British Journal of Clinical Pharmacology. 73, 1, p. 66-76

    Research output: Contribution to journalArticlepeer-review

  216. Published

    Decision-Makers’ Preferences for Approving New Medicines in Wales: A Discrete-Choice Experiment with Assessment of External Validity

    Hughes, D., Linley, W. G. & Hughes, D. A., 1 Apr 2013, In: Pharmacoeconomics. 31, 4, p. 345-355

    Research output: Contribution to journalArticlepeer-review

  217. Published

    A hybrid hydrodynamic lliouvillian approach to non-Markovian dynamics.

    Hughes, K. H., Burghardt, I. & Chattaraj, P. (ed.), 1 Jan 2010, Quantum Trajectories. 2010 ed. Taylor and Francis

    Research output: Chapter in Book/Report/Conference proceedingChapter

  218. Published

    Boltzmann wavepacket dynamics of tunnelling of molecules through symmetric and asymmetric energy barriers on non-periodic potential functions.

    Hughes, K. H. & Macdonald, J. N., 1 Aug 2000, In: Physical Chemistry Chemical Physics. 2, 16, p. 3539-3547

    Research output: Contribution to journalArticlepeer-review

  219. Published

    Climate influences on the cost-effectiveness of vector-based interventions against malaria in elimination scenarios

    Hughes, D., Parham, P. E. & Hughes, D. A., 16 Feb 2015, In: Philosophical Transactions B: Biological Sciences. 370, 1665

    Research output: Contribution to journalArticlepeer-review

  220. Published

    Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Nov 2003, In: Value in Health. 6, 6, p. 749

    Research output: Contribution to journalArticlepeer-review

  221. Published

    Clinical Pharmacology: Special safety considerations in drug development and pharmacovigilance.

    Hughes, D., Atuah, K. N., Hughes, D. A. & Pirmohamed, M., 1 Jan 2004, In: Drug Safety. 27, 8, p. 535-554

    Research output: Contribution to journalArticlepeer-review

  222. Published

    Cost-effectiveness analysis of extended-release formulations of oxybutynin and tolterodine for the management of urge incontinence.

    Hughes, D., Hughes, D. A. & Dubois, D., 1 Jan 2004, In: Pharmacoeconomics. 22, 16, p. 1047-1059

    Research output: Contribution to journalArticlepeer-review

  223. Published

    Pharmacogenetic tests: the need for a level playing field

    Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4

    Research output: Contribution to journalArticlepeer-review

  224. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Deferasirox (Exjade) for the treatment of chronic iron overload due to blood transfusions.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  225. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Tenofovir disoproxil fumarate (Viread) for the treatment of hepatitis B.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  226. Published

    Valuations of epilepsy-specific health states: a comparison of patients with epilepsy and the general population

    Hughes, D., Mulhern, B., Rowen, D., Snape, D., Jacoby, A., Marson, T., Hughes, D. A., Baker, G. & Brazier, J., 1 Jul 2014, In: Epilepsy and Behavior. 36, p. 12-17

    Research output: Contribution to journalArticlepeer-review

  227. Published

    Pharmacokinetic-Pharmacodynamic modelling of Lapdap (CPG-DDS) combination.

    Hughes, D., Hughes, D. A., Watkins, B. & Winstanley, P., 1 Jan 2001, 2001 ed. Unknown.

    Research output: Book/ReportCommissioned report

  228. Published
  229. Published

    Pharmacoeconomic evaluations in Ireland, Scotland and Wales: A Celtic perspective on pharmaceutical assessment

    Hughes, D., Hughes, D. A., Drummond, M., Tolley, K. & Ryan, M., 1 Oct 2007.

    Research output: Contribution to conferencePaper

  230. Published
  231. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  232. Published

    Closure of quantum hydrodynamic moment equations.

    Hughes, K. H., Parry, S. M. & Burghardt, I., 7 Feb 2009, In: Journal of Chemical Physics. 130, 5, p. 054115

    Research output: Contribution to journalArticlepeer-review

  233. Published

    Cost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease

    Hughes, D. & Hughes, D. A., 1 Nov 2003.

    Research output: Contribution to conferencePaper

  234. Published

    Challenges in the Development and Reimbursement of Personalized Medicine—Payer and Manufacturer Perspectives and Implications for Health Economics and Outcomes Research: A Report of the ISPOR Personalized Medicine Special Interest Group

    Hughes, D., Faulkner, E., Annemans, L., Garrison, L., Helfand, M., Holtorf, A. P., Hornberger, J., Hughes, D. A., Li, T., Malone, D., Payne, K., Siebert, U., Towse, A., Veenstra, D. & Watkins, J., 1 Dec 2012, In: Value in Health. 15, 8, p. 1162-1171

    Research output: Contribution to journalArticlepeer-review

  235. Published

    Rationing of drugs for rare diseases

    Hughes, D. & Hughes, D. A., 1 Apr 2006.

    Research output: Contribution to conferencePaper

  236. Published

    Less is more: Medicines that require less frequent administration improve adherence, but are they better?

    Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 3, p. 211-213

    Research output: Contribution to journalArticlepeer-review

  237. Published

    Rationing of drugs for rare diseases.

    Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 4, p. 315-316

    Research output: Contribution to journalArticlepeer-review

  238. Published

    The economics of evergreening.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  239. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Chronic, accelerated or blast phase CML.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  240. Published

    Kd-Jump: a Path-Preserving Stackless Traversal for Faster Isosurface Raytracing on GPUs.

    Hughes, D. M. & Lim, I. S., 1 Nov 2009, In: IEEE Transactions on visualization and computer graphics. 15, 6, p. 1555-1562

    Research output: Contribution to journalArticlepeer-review

  241. Published

    A systematic review and empirical analysis of the relation between dose and duration of drug action.

    Hughes, D., Hughes, D. A. & Aronson, J. K., 1 Jan 2009, p. TP40.

    Research output: Contribution to conferencePaper

  242. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Emtricitabine (Emtriva)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  243. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-naïve patients.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  244. Published

    Effective-mode representation of non-Markovian dynamics: A hierarchical approximation of the spectral density. I. Application to single surface dynamics.

    Hughes, K. H., Christ, C. D. & Burghardt, I., 14 Jul 2009, In: Journal of Chemical Physics. 131, 2, p. 024109

    Research output: Contribution to journalArticlepeer-review

  245. Published

    Kin or self-recognition? Colonial fusibility of the bryozoan Celleporella hyalina.

    Hughes, R. N., Manriquez, P. H., Morley, S., Craig, S. F. & Bishop, J. D., 1 Nov 2004, In: Evolution and Development. 6, 6, p. 431-437

    Research output: Contribution to journalArticlepeer-review

  246. Published

    Orphan drugs revisited: author's response.

    Hughes, D. & Hughes, D. A., 1 May 2006, In: Quarterly Journal of Medicine. 99, 5, p. 350-351

    Research output: Contribution to journalArticlepeer-review

  247. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Mar 2010, In: Clinical Pharmacology and Therapeutics. 87, 3, p. 257-261

    Research output: Contribution to journalArticlepeer-review

  248. Published

    Understanding medication compliance and persistence from an economics perspective

    Hughes, D., Elliot, R. A., Shinogle, J. A., Peele, P., Bhosle, M. & Hughes, D. A., 1 Jan 2008, In: Value in Health. 11, 4, p. 600-610

    Research output: Contribution to journalArticlepeer-review

  249. Published

    Welsh Health Economics Network (WHEN): Scoping Report.

    Hughes, D., Farr, A., O Ceilleachair, A., Cohen, D., Hughes, D. A. & Phillips, C., 1 Jan 2005, 2005 ed. Unknown.

    Research output: Book/ReportCommissioned report

  250. Published

    Development of an economic model to evaluate the cost-effectiveness of rival therapies for treating Crohn’s disease.

    Hughes, D., Kikuchi, T., Bodger, K. & Hughes, D. A., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report