Professor Alexander Yakunin

Professor In Enzyme Discovery and Application

Contact info

 

Professor Alexander Yakunin (Iakounine)

 

Office: Thoday Building, room S25

Email: a.iakounine@bangor.ac.uk

Tel: 01248 388399

 

Research focus: enzyme discovery, enzymology, enzyme applications

  1. Published

    Biochemical and structural insights into enzymatic depolymerization of polylactic acid and other polyesters by microbial carboxylesterases

    Hajighasemi, M., Nocek, B. P., Tchigvintsev, A., Brown, G., Flick, R., Xu, X., Cui, H., Hai, T., Joachimiak, A., Golyshin, P., Savchenko, A., Edwards, E. A. & Yakunin, A. F., 18 Apr 2016, In: Biomacromolecules. 17, 6, p. 2027-2039

    Research output: Contribution to journalArticlepeer-review

  2. Published

    Metabolite Damage and Damage-Control in a Minimal Genome

    Haas, D., Thamm, A. M., Sun, J., Huang, L., Sun, L., Beaudoin, G. A. W., Wise, K. S., Lema-Ortiz, C., Bruner, S. D., Breuer, M., Luthey-Schutten, Z., Lin, J., Wilson, M. A., Brown, G., Yakunin, A., Kurilyak, I., Folz, J., Fiehn, O., Glass, J. I., Hanson, A. D., Henry, C. S. & de Crecy-Lagard, V., 30 Aug 2022, In: mBio. e0163022.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica

    Golyshina, O., Hai, T., Kube, M., Chernikova, T. N., Al-Ramahi, Y., Beloqui, A., Lopez-Cortez, N., Guazzaroni, M. E., Heipieper, H. J., Klages, S., Kotsyurbenko, O. R., Langer, I., Nechitaylo, T. Y., Lünsdorf, H., Fernández, M., Juárez, S., Ciordia, S., Singer, A., Kagan, O., Egorova, O., Petit, P. A., Stogios, P., Kim, Y., Tchigvintsev, A., Flick, R., Denaro, R., Genovese, M., Albar, J. P., Reva, O. N., Martínez-Gomariz, M., Tran, H., Ferrer, M., Savchenko, A., Yakunin, A. F., Yakimov, M. M., Golyshina, O. V., Reinhardt, R. & Golyshin, P. N., 23 Jul 2013, In: Nature Communications. 4, p. 2156

    Research output: Contribution to journalArticlepeer-review

  4. Published

    Metabolic and evolutionary patterns in the extremely acidophilic archaeon Ferroplasma acidiphilum YT

    Golyshina, O., Hai, T., Reva, O. N., Lemak, S., Yakunin, A. F., Goesmann, A., Nechitaylo, T. Y., LaCono, V., Smedile, F., Slesarev, A., Rojo, D., Barbas, C., Ferrer, M., Yakimov, M. M. & Golyshin, P., 16 Jun 2017, In: Scientific Reports. 7, 3682.

    Research output: Contribution to journalArticlepeer-review

  5. Published

    One-pot biocatalytic transformation of adipic acid to 6-aminocaproic acid and 1,6-hexamethylenediamine using carboxylic acid reductases and transaminases

    Fedorchuk, T. P., Khusnutdinova, A. N., Evdokimova, E., Flick, R., Di Leo, R., Stogios, P. J., Savchenko, A. & Yakunin, A., 15 Jan 2020, In: Journal of the American Chemical Society. 142, 2, p. 1038-1048 11 p.

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Site-directed mutagenesis and stability of the carboxylic acid reductase MAB4714 from Mycobacterium abscessus

    Fedorchuk, T. P., Khusnutdinova, A. N., Flick, R. & Yakunin, A., 10 Sept 2019, In: Journal of Biotechnology. 303, p. 72-79

    Research output: Contribution to journalArticlepeer-review

  7. Published

    Thermophilic Carboxylesterases from Hydrothermal Vents of the Volcanic Island of Ischia Active on Synthetic and Biobased Polymers and Mycotoxins

    Distaso, M., Chernikova, T., Bargiela, R., Coscolín, C., Stogios, P. J., Gonzalez-Alfonso, J. L., Lemak, S., Khusnutdinova, A., Plou, F. J., Evdokimova, E., Savchenko, A., Lunev, E., Yakimov, M. M., Golyshina, O., Ferrer, M., Yakunin, A. & Golyshin, P., 28 Feb 2023, In: Applied and Environmental Microbiology. 89, 2, p. e0170422 20 p.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    A microplate screen to estimate metal-binding affinities of metalloproteins

    Diep, P., Mahadevan, R. & Yakunin, A. F., 15 Nov 2020, In: Analytical biochemistry. 609, p. 113836

    Research output: Contribution to journalArticlepeer-review

  9. E-pub ahead of print

    Ni(II)-binding affinity of CcNikZ-II and its homologs: the role of the HH-prong and variable loop revealed by structural and mutational studies

    Diep, P., Stogios, P. J., Evdokimova, E., Savchenko, A., Mahadevan, R. & Yakunin, A. F., 31 Mar 2024, (E-pub ahead of print) In: Febs Journal.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Heavy metal removal by bioaccumulation using genetically engineered microorganisms

    Diep, P., Mahadevan, R. & Yakunin, A., 29 Oct 2018, In: Frontiers in Bioengineering and Biotechnology. 6, 157.

    Research output: Contribution to journalArticlepeer-review