Dyfrig Hughes - Research outputs

Published

Biosimilars: Evidential standards for health technology assessment.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Biosimilars: Evidential standards for health technology assessment.

Hughes, D. & Hughes, D. A., 1 Mar 2010, In: Clinical Pharmacology and Therapeutics. 87, 3, p. 257-261

Research output: Contribution to journal › Article › peer-review

Published

CARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial

Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Feb 2019, In: Trials. 20, 1, 16 p., 105.

Research output: Contribution to journal › Article › peer-review

Published

CATheter Infections in CHildren (CATCH): a randomised controlled trial and economic evaluation comparing impregnated and standard central venous catheters in children

Harron, K., Mok, Q., Dwan, K., Ridyard, C., Mott, T., Millar, M., Ramnarayan, P., Tibby, S. M., Muller-Pebody, B., Hughes, D., Gamble, C. & Gilbert, R. E., Mar 2016, In: Health Technology Assessment. 20, 18

Research output: Contribution to journal › Article › peer-review

Published

Carer administration of as-needed sub-cutaneous medication for breakthrough symptoms in people dying at home: the CARiAD feasibility RCT

Poolman, M., Roberts, J., Wright, S., Hendry, A., Goulden, N., Holmes, E., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., O'Connor, J., Foster, B., Reymond, L., Healy, S., Lewis, P., Wee, B., Johnstone, R. P., Roberts, R., Parkinson, A., Roberts, S. & Wilkinson, C., 2 Jun 2020, In: Health Technology Assessment. 24, 25, 150 p.

Research output: Contribution to journal › Article › peer-review

Published

Carer-administration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARIAD)

Wilkinson, C., Poolman, M., Roberts, J., Wee, B., Hiscock, J., Hughes, D., Nelson, A., Perkins, P., Johnstone, R. P., Reymond, E., Foster, B., O'Connor, J., Jones, S., Hoare, Z., Roberts, R., Byrne, A., Healy, S. & Lewis, P., 1 Sept 2017.

Research output: Contribution to conference › Poster › peer-review

Published

Challenges for economic evaluation of strategies to contain antimicrobial resistance

Holmes, E. & Hughes, D., 27 Sept 2019, In: Antibiotics. 8, 4, 8 p., 166.

Research output: Contribution to journal › Comment/debate › peer-review

Published

Challenges in the Development and Reimbursement of Personalized Medicine—Payer and Manufacturer Perspectives and Implications for Health Economics and Outcomes Research: A Report of the ISPOR Personalized Medicine Special Interest Group

Hughes, D., Faulkner, E., Annemans, L., Garrison, L., Helfand, M., Holtorf, A. P., Hornberger, J., Hughes, D. A., Li, T., Malone, D., Payne, K., Siebert, U., Towse, A., Veenstra, D. & Watkins, J., 1 Dec 2012, In: Value in Health. 15, 8, p. 1162-1171

Research output: Contribution to journal › Article › peer-review

Published

Changing Agendas on Sleep, Treatment and Learning in Epilepsy (CASTLE) Sleep-E: A protocol for a randomised controlled trial comparing an online behavioural sleep intervention with standard care in children with Rolandic epilepsy

Al-Najjar, N., Bray, L., Carter, B., Collingwood, A., Cook, G., Crudgington, H., Dietz, K., Hardy, W., Hiscock, H., Hughes, D., Morris, C., Rouncefield-Swales, A., Saron, H., Spowart, C., Stibbs-Easton, L., Tudur Smith, C., Watson, V., Whittle, L., Wiggs, L., Wood, E., Gringas, P. & Pal, D. K., 10 Mar 2023, In: BMJ Open. 13, 3, e065769.

Research output: Contribution to journal › Article › peer-review

Published

Charitable contributions to funding cancer services for children and young people in England and Wales

Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2008, In: Journal of Child Health Care. 12, 2, p. 156-168

Research output: Contribution to journal › Article › peer-review

Published

Chiral chromatography: Costs of chiral switching.

Hughes, D. & Hughes, D. A., 1 Jan 2008, In: Pharmaceutical Journal. 281, p. 213

Research output: Contribution to journal › Article › peer-review

Published

Choice of oral anticoagulant prescribed by general practices in Wales: Application of Dirichlet regression and linked data

Hill-McManus, D. & Hughes, D., Jun 2022, In: British Journal of Clinical Pharmacology. 88, 6, p. 2782-2792 11 p.

Research output: Contribution to journal › Article › peer-review

Published

Cisplatin plus vinorelbine or gemcitabine in patients with advanced non-small cell lung cancer: Pharmacoeconomic considerations.

Hughes, D. & Hughes, D. A., 1 Jul 2005, In: European Journal of Cancer. 41, 11, p. 1655

Research output: Contribution to journal › Article › peer-review

Published

Climate influences on the cost-effectiveness of vector-based interventions against malaria in elimination scenarios

Hughes, D., Parham, P. E. & Hughes, D. A., 16 Feb 2015, In: Philosophical Transactions B: Biological Sciences. 370, 1665

Research output: Contribution to journal › Article › peer-review

Published

Clinical Pharmacology: Special safety considerations in drug development and pharmacovigilance.

Hughes, D., Atuah, K. N., Hughes, D. A. & Pirmohamed, M., 1 Jan 2004, In: Drug Safety. 27, 8, p. 535-554

Research output: Contribution to journal › Article › peer-review

Published

Clinical and econnomic importance of completion of therapy in the treatment of LRTIs

Hughes, D. & Hughes, D. A., 1 Sept 2006.

Research output: Contribution to conference › Paper

Published

Clinical interventions to improve adherence to urate-lowering therapy in patients with gout: a systematic review

Sinnappah, K. A., Stocker, S. L., Chan, J. S., Hughes, D. A. & Wright, D. F. B., 25 Jun 2022, In: International Journal of Pharmacy Practice. 30, 3, p. 215-225 11 p.

Research output: Contribution to journal › Article › peer-review

Published

Combining model-based clinical trial simulation, pharmacoeconomics and value of information to optimize trial design

Hill-McManus, D. & Hughes, D., Jan 2021, In: CPT: Pharmacometrics & Systems Pharmacology . 10, 1, p. 75-83 9 p.

Research output: Contribution to journal › Article › peer-review

Published

Community views on factors affecting medicines resource allocation: Cross-sectional survey of 3080 adults in Australia

Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 2019, In: Australian Health Review . 43, 3, p. 254-260

Research output: Contribution to journal › Article › peer-review

Published

Comparative Effectiveness of Dabigatran, Rivaroxaban, Apixaban, and Warfarin in the Management of Patients With Nonvalvular Atrial Fibrillation

Hughes, D., Pink, J., Pirmohamed, M. & Hughes, D. A., 25 Apr 2013, In: Clinical Pharmacology and Therapeutics.

Research output: Contribution to journal › Article › peer-review

Published

Comparison of regression methods for the cost effectiveness analysis of clinical trials with a small population size: the sycamore and folated trials

Culeddu, G., Hughes, D. & Welton, N., 10 Jul 2017.

Research output: Contribution to conference › Poster › peer-review

Published

Comparisons between the medication possession ratio (MPR) and gaps measures of medication compliance: are we selling ourselves short by relying on the MPR?

Hughes, D., Nichol, M., Manias, E., Hughes, D. A. & Schabert, V. F., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Conducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches

Hughes, D., Charles, J. M., Dawoud, D. M., Edwards, R. T., Holmes, E. A., Jones, C. L., Parham, P., Plumpton, C., Ridyard, C. O., Lloyd-Williams, H., Wood, E. M. & Yeo, S., May 2016, In: Pharmacoeconomics. 34, 5, p. 447-461

Research output: Contribution to journal › Article › peer-review

Published

Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey

Thorn, J., Davies, C. F., Brookes, S., Noble, S., Dritsaki, M., Gray, E., Hughes, D., Mihaylova, B., Petrou, S., Ridyard, C., Sach, T., Wilson, E., Wordsworth, S. & Hollingworth, W., 1 Apr 2021, In: Value in Health. 24, 4, p. 539-547 9 p.

Research output: Contribution to journal › Article › peer-review

Published

Continuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis

Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A582

Research output: Contribution to journal › Article › peer-review

Published

Continuous subcutaneous insulin infusion compated to multiple daily injection regimens in children and yung people at diagnosis of type 1 diabetes: A pragmatic randomised controlled trial and economic evaluation (scipi trial)

Blair, J., Mckay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., John, G., Hughes, D. & Gamble, C., Sept 2017, p. 22-23.

Research output: Contribution to conference › Abstract › peer-review

Published

Continuous subcutaneous insulin infusion versus multiple daily injection regimens in children and young people at diagnosis of type 1 diabetes: pragmatic randomised controlled trial and economic evaluation

Blair, J. C., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. A. & Gamble, C., 3 Apr 2019, In: British Medical Journal. 365, p. l1226 l1226.

Research output: Contribution to journal › Article › peer-review

Published

Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT

Blair, J., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. & Gamble, C., Aug 2018, In: Health Technology Assessment. 22, 42, p. 1-112 112 p.

Research output: Contribution to journal › Article › peer-review

Published

Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus

Crudgington, H., Rogers, M., Bray, L., Carter, B., Currier, J., Gibbon, F., Hughes, D., Lyle, S., Roberts, D., Smith, C. T., Gringras, P., Pal, D. & Morris, C., May 2019, In: Epilepsia. 60, 5, p. 857-871

Research output: Contribution to journal › Article › peer-review

Published

Core items for a standardised resource-use measure (ISRUM):expert Delphi consensus survey

Thorn, J., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., 7 May 2017, p. P265. 1 p.

Research output: Contribution to conference › Poster › peer-review

Published

Core items for a standardized resource-use measure (ISRUM): expert Delphi consensus survey

Thom, J., Brookes, S. T., Ridyard, C., Riley, R., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., Jun 2018, In: Value in Health. 21, 6, p. 640-649

Research output: Contribution to journal › Article › peer-review

Published

Cost and clinical consequence of antibiotic non-adherence in acute exacerbations of chronic bronchitis.

Sorensen, S. V., Baker, T., Fleurence, R., Dixon, J., Roberts, C., Haider, S. & Hughes, D., 1 Aug 2009, In: International Journal of Tuberculosis and Lung Disease. 13, 8, p. 945-954

Research output: Contribution to journal › Article › peer-review

Published

Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout

Plumpton, C., Alfirevic, A., Pirmohamed, M. & Hughes, D., 1 Oct 2017, In: Rheumatology. 56, 10, p. 1729-1739

Research output: Contribution to journal › Article › peer-review

Published

Cost effectiveness analysis of treatments for children with uncontrolled asthma symptoms despite taking inhaled corticosteroids

Culeddu, G., Sinha, I., Donegan, S., Maden, M., Cividini, S., Rose, K., Fulton, O., Turner, S., Tudor-Smith, C. & Hughes, D., 27 Oct 2023, In: European Respiratory Journal. 62 , Supplement 67, PA 523.

Research output: Contribution to journal › Meeting Abstract › peer-review

Published

Cost effectiveness of pharmacogenetic screening prior to initiation of carbamazepine treatment for epilepsy

Plumpton, C. O., Yip, V., Alfirevic, A., Marson, A., Pirmohamed, M. & Hughes, D., Nov 2013, In: Value in Health. 16, 7, p. A624-A624

Research output: Contribution to journal › Article › peer-review

Published

Cost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease

Hughes, D. & Hughes, D. A., 1 Nov 2004, In: Value in Health. 7, 6, p. 753

Research output: Contribution to journal › Article › peer-review

Published

Cost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease.

Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Feb 2005, In: Expert Review of Pharmacoeconomics and Outcomes Research. 5, 1, p. 29-38

Research output: Contribution to journal › Article › peer-review

Published

Cost of non-compliance and non-persistence with medications for diabetes mellitus

Hughes, D., Salas, M., Hughes, D. A., Lebmeier, M. & Vardeva, K., 1 Aug 2007.

Research output: Contribution to conference › Paper

Published

Cost-Effectiveness Analysis of Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa

Culeddu, G., Brogan, P. A. & Hughes, D., 2021.

Research output: Contribution to conference › Other › peer-review

Published

Cost-Effectiveness Analysis of the Use of Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing in Primary Care

Holmes, E., Harris, S. D., Hughes, A., Craine, N. & Hughes, D., 7 Dec 2018, In: Antibiotics. 7, 4, 19 p., 106.

Research output: Contribution to journal › Article › peer-review

Published

Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation

Hughes, D., Pink, J., Pirmohamed, M., Lane, S. & Hughes, D. A., 23 Sept 2013, In: Clinical Pharmacology and Therapeutics.

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity

Hughes, D., Hughes, D. A., Vilar, F. J., Ward, C. C., Alfirevic, A., Park, B. K. & Pirmohamed, M., 1 Jun 2004, In: Pharmacogenetics. 14, 6, p. 335-342

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis

Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. 415-424

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.

Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25

Research output: Contribution to journal › Letter › peer-review

Published

Cost-effectiveness analysis of extended-release formulations of oxybutynin and tolterodine for the management of urge incontinence.

Hughes, D., Hughes, D. A. & Dubois, D., 1 Jan 2004, In: Pharmacoeconomics. 22, 16, p. 1047-1059

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

Research output: Contribution to conference › Paper

Published

Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

Research output: Contribution to conference › Paper

Published

Cost-effectiveness considerations in pharmacogenetics.

Hughes, D. & Hughes, D. A., 1 Jan 2008.

Research output: Contribution to conference › Paper

Published

Cost-effectiveness of HLA-B*15:02 screening in Malaysia

Plumpton, C. & Hughes, D., Oct 2017, In: British Journal of Dermatology. 177, 4, p. 904-905

Research output: Contribution to journal › Comment/debate

Published

Cost-effectiveness of biological therapy for Crohn's disease: Markov cohort analyses incorporating United Kingdom patient-level cost data.

Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Aug 2009, In: Alimentary Pharmacology and Therapeutics. 30, 3, p. 265-274

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness of home versus hospital management of children at onset of Type 1 Diabetes: The DECIDE randomised controlled trial

McCarroll, Z., Townson, J., Pickles, T., Gregory, J. W., Playle, R., Robling, M. & Hughes, D., 19 May 2021, In: BMJ Open. 11, 5, e043523.

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial

Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Sept 2017, In: Frontiers in Pharmacology. 8, 644.

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework

Plumpton, C., Pirmohamed, M. & Hughes, D., Jun 2019, In: Clinical Pharmacology and Therapeutics. 105, 6, p. 1429-1438

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden

Verhoef, T. I., Redekop, W. K., Langenskiold, S., Kamali, F., Wadelius, M., Burnside, G., Maitland-van der Zee, A. H., Hughes, D. & Pirmohamed, M., Oct 2016, In: The Pharmacogenomics Journal. 16, p. 478–484

Research output: Contribution to journal › Article › peer-review

Published

Cost-effectiveness of screening for HLA-A*31:01 prior to initiation of carbamazepine in epilepsy

Plumpton, C., Yip, V. L. M., Alfirevic, A., Marson, A. G., Pirmohamed, M. & Hughes, D., Apr 2015, In: Epilepsia.

Research output: Contribution to journal › Article › peer-review

Published

Cost-utility analysis of on demand rabeprazole and esomeprazole for symptomatic gastro oesophageal reflux disease

Hughes, D., Hughes, D. A. & Dubois, D., 1 Nov 2003, In: Value in Health. 6, 6, p. 613

Research output: Contribution to journal › Article › peer-review

Published

Cost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease

Hughes, D. & Hughes, D. A., 1 Nov 2003.

Research output: Contribution to conference › Paper

Published

Cost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease

Hughes, D. & Hughes, D. A., 1 Nov 2003.

Research output: Contribution to conference › Paper

Published

Costs of Medication Nonadherence in Patients with Diabetes Mellitus: A Systematic Review and Critical Analysis of the Literature.

Hughes, D., Salas, M., Hughes, D. A., Zuluaga, A., Vardeva, K. & Lebmeier, M., 1 Sept 2009, In: Value in Health. 12, 6, p. 915-922

Research output: Contribution to journal › Article › peer-review

Published

Costs of non-compliance to antipsychotic medications among patients with schizophrenia.

Hughes, D., Hughes, D. A., Salas, M., Zuluaga, A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 May 2008.

Research output: Contribution to conference › Paper

Published

Costs of orphan medicinal products: longitudinal analysis of expenditure in Wales

Pijeira Perez, Y., Wood, E. & Hughes, D., 1 Nov 2023, In: Orphanet Journal of Rare Diseases. 18, 1, 342.

Research output: Contribution to journal › Article › peer-review

Published

Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417

Research output: Contribution to journal › Article › peer-review

Published

Current assessment of risk-benefit by regulators: Is it time to introduce decision analyses?

Hughes, D., Hughes, D. A., Pirmohamed, M. & Bayoumi, A., 1 Aug 2007.

Research output: Contribution to conference › Paper

Published

Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Aug 2007, In: Clinical Pharmacology and Therapeutics. 82, 2, p. 123-127

Research output: Contribution to journal › Article › peer-review

Published

Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses

Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., N. V., 31 Oct 2011, In: British Medical Journal. 343, p. 1-14

Research output: Contribution to journal › Article › peer-review

Published

Decision analytic modelling methods for the assessing the effectiveness of treatment sequences for clinical and economic decision making: a methodological review

Lewis, R., Hughes, D. & Wilkinson, C., 30 Nov 2017, In: Value in Health. 20, 9, p. A748 1 p.

Research output: Contribution to journal › Article › peer-review

Published

Decision-Makers’ Preferences for Approving New Medicines in Wales: A Discrete-Choice Experiment with Assessment of External Validity

Hughes, D., Linley, W. G. & Hughes, D. A., 1 Apr 2013, In: Pharmacoeconomics. 31, 4, p. 345-355

Research output: Contribution to journal › Article › peer-review

Published

Defining rewardable innovation in drug therapy

Hughes, D., Aronson, J. K., Ferner, R. E. & Hughes, D. A., 1 Apr 2012, In: Nature Reviews Drug Discovery. 11, p. 253-254

Research output: Contribution to journal › Article › peer-review

Published

Developing an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project

Holmes, E., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Foster, D., Hardman, K., Bell, S., Marson, A., Hughes, D. & Noble, A. J., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 28-37 10 p.

Research output: Contribution to journal › Article › peer-review

Accepted/In press

Developing feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed methods study

Noble, A. J., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Morris, B., Hughes, D., Marson, T. & Holmes, E., 6 Jun 2023, (Accepted/In press) In: Health Services and Delivery Research (HS&DR).

Research output: Contribution to journal › Article › peer-review

Published

Developing patient-centred, feasible alternative care for adult emergency department users with epilepsy: Protocol for the mixed-methods observational ‘Collaborate’ project.

Noble, A. J., Mathieson, A., Ridsdale, L., Holmes, E., Morgan, M., McKinlay, A., Dickson, J., Jackson, M., Hughes, D., Goodacre, S. & Marson, A. G., 2 Nov 2019, In: BMJ Open. 9, 11, e031696.

Research output: Contribution to journal › Article › peer-review

Published

Development of a Database of Instruments for Resource-Use Measurement: Purpose, Feasibility, and Design

DIRUM Team, 1 Jul 2012, In: Value in Health. 15, 5, p. 650-655

Research output: Contribution to journal › Article › peer-review

Published

Development of an economic model to evaluate the cost-effectiveness of rival therapies for treating Crohn’s disease.

Hughes, D., Kikuchi, T., Bodger, K. & Hughes, D. A., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Do guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review

Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Jul 2018, In: Thorax. 73, 7, p. 670-673

Research output: Contribution to journal › Letter › peer-review

Published

Does Electronic Monitoring Influence Adherence to Medication? Randomized Controlled Trial of Measurement Reactivity

Hughes, D., Sutton, S., Kinmonth, A. L., Hardeman, W., Hughes, D. A., Boase, S., Prevost, T., Kellar, I., Graffy, J., Griffin, S. & Farmer, A., 1 Dec 2014, In: Annals of Behavioral Medicine. 48, 3, p. 293-299

Research output: Contribution to journal › Article › peer-review

Published

Drug compliance and pharmaceconomics

Hughes, D. & Hughes, D. A., 1 Dec 2003.

Research output: Contribution to conference › Paper

Published

Drug evaluation and pharmocoeconomics.

Hughes, D., Krska, J., Hughes, D. A., Winfield, A. J. (ed.), Rees, J. A. (ed.) & Smith, I. (ed.), 1 Jan 2009, Pharmaceutical Practice: 4th Edition.. 2009 ed. Churchill Livingstone, p. 185-198

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Published

Drugs for exceptionally rare diseases: do they deserve special status for funding?

Hughes, D., Tunnage, B. & Yeo, S. T., 1 Nov 2005, In: QJM - An International Journal of Medicine. 98, 11, p. 829-836

Research output: Contribution to journal › Article › peer-review

Published

ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

De Geest, S., Zullig, L. L., Dunbar-Jacob, J., Helmy, R., Hughes, D., Wilson, I. & Vrijens, B., 3 Jul 2018, In: Annals of Internal Medicine. 169, 1, p. 30-35

Research output: Contribution to journal › Article › peer-review

Published

Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales

Gillespie, D., Knapper, C., Hughes, D., Couzen, Z., Wood, F., de Bruin, M., Ma, R., Jones, A. T., Williams, A. & Hood, K., 17 Feb 2021, In: Sexually transmitted infections. 97, 2, p. 85-87 3 p., 054598.

Research output: Contribution to journal › Article › peer-review

Published

Economic Studies in Motor Neurone Disease: A Systematic Methodological Review

Moore, A., Young, C. A. & Hughes, D., Apr 2017, In: Pharmacoeconomics. 35, 4, p. 397-413

Research output: Contribution to journal › Article › peer-review

Published

Economic analysis of on-demand maintenance therapy with proton pump inhibitors in patients with non-erosive reflux disease.

Hughes, D., Hughes, D. A., Bodger, K., Bytzer, P., De Herdt, D. & Dubois, D., 1 Jan 2005, In: Pharmacoeconomics. 23, 10, p. 1031-1041

Research output: Contribution to journal › Article › peer-review

Published

Economic considerations for market access of new health technologies: A case study of pharmacogenetic testing

Hughes, D. & Hughes, D. A., 1 Feb 2008.

Research output: Contribution to conference › Paper

Published

Economic considerations for pharmacogenetic testing

Hughes, D. & Hughes, D. A., 1 Jun 2008.

Research output: Contribution to conference › Paper

Published

Economic evaluation during early (phase II) trials

Hughes, D. & Hughes, D. A., 1 Nov 2002.

Research output: Contribution to conference › Paper

Published

Economic evaluation of a behavior-modifying intervention to enhance antiepileptic drug adherence

Hughes, D., Plumpton, C. O., Brown, I., Reuber, M., Marson, A. G. & Hughes, D. A., 26 Mar 2015, In: Epilepsy and Behavior. 45, p. 180-186

Research output: Contribution to journal › Article › peer-review

Published

Economic evaluation of infliximab and adalimumab for Crohn's disease.

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Economic evaluation of on-demand maintenance therapy with proton pump inhibitors in patients with symptomatic gastroesophageal reflux disease - a Monte-Carlo analysis for Italy

Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Oct 2004.

Research output: Contribution to conference › Paper

Published

Economic evaluation of steroid injections (methylprednisolone) in the treatment of Morton's neuroma: patient-blind randomised trial

Hughes, D., Thomson, C., Beggs, I., Martin, D., McCaldin, D., Russell, D., Edwards, R. T., Hughes, D. A., Yeo, S. T., Russell, I. T. & Gibson, T. N., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Economic evaluations during early (Phase II) drug development: A role for clinical trial simulations.

Hughes, D., Hughes, D. A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 11, p. 1069-1077

Research output: Contribution to journal › Article › peer-review

Published

Economic impact of poor compliance with pharmaceuticals.

Hughes, D. & Hughes, D. A., 1 Aug 2002, In: Expert Review of Pharmacoeconomics and Outcomes Research. 2, 4, p. 327-335

Research output: Contribution to journal › Article › peer-review

Published

Economics of pharmacogenetic guided treatments: Underwhelming or overstated?

Hughes, D., May 2018, In: Clinical Pharmacology and Therapeutics. 103, 5, p. 749-751

Research output: Contribution to journal › Article › peer-review

Published

Effectiveness of out-patient based acute heart failure care: A pilot randomised controlled trial

Wong, K. Y. K., Hughes, D., Debski, M., Latt, N., Assaf, O., Abdelrahman, A., Taylor, R., Allgar, V., McNeill, L., Howard, S., Wong, S. Y. S., Jones, R., Cassidy, C. J., Seed, A., Galasko, G., Clark, A., Davis, G. K., Montasem, A., Lang, C. C., Kalra, P. R., Campbell, R., Lip, G. Y. H. & Cleland, J. G. F., Oct 2023, In: Acta Cardiologica. 78, 7, p. 828-837 10 p.

Research output: Contribution to journal › Article › peer-review

Published

Effects of the abolition of prescription charges in Wales: A preliminary analysis

Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

Research output: Contribution to conference › Paper

Published

Effects of the abolition of prescription charges in Wales: a preliminary analysis.

Hughes, D., Cohen, D., Alam, M. F., Hughes, D. A., Dunstan, F. & Routledge, P., 1 Jan 2008, In: International Journal of Pharmacy Practice. 16, Supplement 1, p. A39

Research output: Contribution to journal › Article › peer-review

Published

Eliciting patients' preferences using a discrete choice experiment questionnaire: the role played by qualitative data in questionnaire design

Hughes, D., Longo, M., Hughes, D. A., Myles, S. & Lisles, C., 1 Mar 2006.

Research output: Contribution to conference › Paper

Published

Empirical analysis of the relationship between dose and duration of drug action

Hughes, D. & Hughes, D. A., 1 Jun 2005.

Research output: Contribution to conference › Paper

Published

Engaging with the MRC Methodology Hubs – NWHTMR.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

Enhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.

Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Jan 2010.

Research output: Contribution to conference › Paper

Published

EstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): Protocol for a systematic review, network meta-analysis and cost-effectiveness analysis using individual participant data (IPD)

Cividini, S., Sinha, I., Donegan, S., Maden, M., Culeddu, G., Rose, K., Fulton, O., Hughes, D., Turner, S. & Smith, C. T., 5 Feb 2021, In: BMJ Open. 11, e040528.

Research output: Contribution to journal › Article › peer-review

Research Portal

Professor Dyfrig Hughes

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