Dr Ramsay Mcfarlane
Senior Lecturer in Biomedical Sciences (Medical & Molecular Genetics)

Affiliations
Contact info
Location: Brambell, Room 405
Phone: 2360
Email: r.macfarlane@bangor.ac.uk
Position: Senior Lecturer / Research Group Leader / Deputy Head of School – Research
- Article › Research › Peer-reviewed
- Published
5-azacytidine treatment of the fission yeast leads to cytotxicity and cell cycle arrest.
Taylor, E. M., Mcfarlane, R. & Price, C., 1996, In: Molecular Genetics and Genomics. 253, 1-2, p. 128-137Research output: Contribution to journal › Article › peer-review
- Published
A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets
Sammut, S. J., Feichtinger, J., Stuart, N. S., Wakeman, J., Larcombe, L. & Mcfarlane, R. J., 6 May 2014, In: Oncoscience. 1, 5, p. 349-359Research output: Contribution to journal › Article › peer-review
- Published
A role for recombination in centromere function.
Mcfarlane, R. J., McFarlane, R. J. & Humphrey, T. C., 1 May 2010, In: Trends in Genetics. 26, 5, p. 209-213Research output: Contribution to journal › Article › peer-review
- Published
Biological roles of translin and translin-associated factor-X: RNA metabolism comes to the fore.
Mcfarlane, R. J., Jaendling, A. & McFarlane, R. J., 15 Jul 2010, In: Biochemical Journal. 429, 2, p. 225-234Research output: Contribution to journal › Article › peer-review
- Published
Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer
Jezkova, J., Williams, J. S., Pinto, F., Sammut, S. J., Williams, G. T., Gollins, S., Mcfarlane, R. J., Reis, R. M. & Wakeman, J., 5 Feb 2016, In: Oncotarget. 2016, 7, p. 11478-11486Research output: Contribution to journal › Article › peer-review
- Published
Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathway
Mcfarlane, R. J., Gollins, S. W., Wakeman, J., Jezkova, J., Williams, J. S., Jones-Hutchins, F., Sammut, S. J., Gollins, S., Cree, I., Coupland, S., McFarlane, R. J. & Wakeman, J. A., 21 May 2014, In: Oncotarget. 5, 11, p. 3813-3822Research output: Contribution to journal › Article › peer-review
- Published
Brachyury: Strategies for Drugging an Intractable Cancer Therapeutic Target
Robinson, H., McFarlane, R. J. & Wakeman, J. A., Apr 2020, In: Trends in cancer. 6, 4, p. 271-273 3 p.Research output: Contribution to journal › Article › peer-review
- Published
Cancer germline gene activation: Friend or foe?
Mcfarlane, R. J., McFarlane, R. J., Feichtinger, J. & Larcombe, L., 23 Jun 2014, In: Cell Cycle. 13, 14, p. 2151-2152Research output: Contribution to journal › Article › peer-review
- Published
Cancer/Testis Antigens and Colorectal Cancer
Sammut, S. J., Wakeman, J., Mcfarlane, R. J., Sammut, J., Wakeman, J. A., Stuart, N. & McFarlane, R. J., 13 Jun 2013, In: Journal of Genetic Syndromes and Gene Therapy. 4, 5, p. 149Research output: Contribution to journal › Article › peer-review
- Published
CancerEST: a web-based tool for automatic meta-analysis of public EST data
Mcfarlane, R. J., Feichtinger, J., McFarlane, R. J. & Larcombe, L. D., 27 Feb 2014, In: Database: The Journal of Biological Databases and Curation. 2014Research output: Contribution to journal › Article › peer-review
- Published
CancerMA: a web-based tool for automatic meta-analysis of public cancer microarray data.
Feichtinger, J., Mcfarlane, R. & Larcombe, L., 15 Dec 2012, In: Database: The Journal of Biological Databases and Curation. 2012, bas055.Research output: Contribution to journal › Article › peer-review
- Published
Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function.
Mcfarlane, R., Carr, A. M. & Price, C., 1 Jul 1997, In: Molecular Genetics and Genomics. 255, 3, p. 332-340Research output: Contribution to journal › Article › peer-review
- Published
Comparative proteomic analysis reveals differential expression of Hsp25 following the directed differentiation of mouse embryonic stem cells.
Wakeman, J., Mcfarlane, R. J., Battersby, A., Jones, R. D., Lilley, K. S., McFarlane, R. J., Braig, H. R., Allen, N. D. & Wakeman, J. A., 1 Feb 2007, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1773, 2, p. 147-156Research output: Contribution to journal › Article › peer-review
- Published
Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe.
Mcfarlane, R. J., Pryce, D. W., Lorenz, A., Smirnova, J. B., Loidl, J. & McFarlane, R. J., 1 May 2005, In: Genetics. 170, 1, p. 95-106Research output: Contribution to journal › Article › peer-review
- Published
Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX.
Mcfarlane, R. J., Jaendling, A., Ramayah, S., Pryce, D. W. & McFarlane, R. J., 1 Feb 2008, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1783, 2, p. 203-213Research output: Contribution to journal › Article › peer-review
- Published
Germline/meiotic genes in cancer: new dimensions
Mcfarlane, R. J., McFarlane, R. J., Feichtinger, J. & Larcombe, L., 19 Mar 2015, In: Cell Cycle. 14, 6, p. 791-792Research output: Contribution to journal › Article › peer-review
- Published
Homologous chromosome pairing in Schizosaccharomyces pombe
Mcfarlane, R. J., Wells, J. L., Pryce, D. W. & McFarlane, R. J., 15 Oct 2006, In: Yeast. 23, 13, p. 977-989Research output: Contribution to journal › Article › peer-review
- Published
Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis
Planells Palop, V., Hazazi, A., Feichtinger, J., Jezkova, J., Thallinger, G. G., Alsiwiehri, N., Almutairi, M., Parry, L., Wakeman, J. & Mcfarlane, R., 26 Apr 2017, In: Molecular Cancer. 16, 1, p. 1-18 84.Research output: Contribution to journal › Article › peer-review
- Published
Identification of a class of human cancer germline genes with transcriptional silencing refractory to the hypomethylating drug 5-aza-2'-deoxycytidine
Almatrafi, A., Feichtinger, J., Vernon, E. G., Escobar, N. G., Wakeman, J. A., Larcombe, L. D. & McFarlane, R. J., 10 Nov 2014, In: Oncoscience. 1, 11, p. 745-750 6 p.Research output: Contribution to journal › Article › peer-review
- Published
Linear element-independent meiotic recombination in Schizosaccharomyces pombe.
Mcfarlane, R. J., Wells, J. L., Pryce, D. W., Estreicher, A., Loidl, J. & McFarlane, R. J., 1 Nov 2006, In: Genetics. 174, 3, p. 1105-1114Research output: Contribution to journal › Article › peer-review
- Published
Meiosis-like functions in oncogenesis: a new view of cancer.
Mcfarlane, R. & Wakeman, J., Nov 2017, In: Cancer Research. 77, 21, p. 5712-5716Research output: Contribution to journal › Article › peer-review
- Published
Meiotic gene activation in somatic and germ cell tumours
Mcfarlane, R. & Feichtinger, J., Jul 2019, In: Andrology. 7, 4, p. 415-427 13 p.Research output: Contribution to journal › Article › peer-review
- Published
Meta-analysis of cancer microarray data sets reveals a germ line expression profile in ovarian cancers: new biomarkers and potential drug targets
Mcfarlane, R. J. & McFarlane, R., 15 Aug 2015, In: Clinical Cancer Research. 21, 16Research output: Contribution to journal › Article › peer-review
- Published
Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes.
Stuart, N. S., Wakeman, J., Mcfarlane, R. J., Feichtinger, J., Aldeailej, I., Anderson, R., Almutairi, M., Almatrafi, A., Alsiwiehri, N., Griffiths, K., Stuart, N., Wakeman, J. A., Larcombe, L. & McFarlane, R. J., 13 Aug 2012, In: Oncotarget. 3, 8, p. 843-853Research output: Contribution to journal › Article › peer-review
- Published
Meta-analysis of expression of l(3)mbt tumor-associated germline genes supports the model that a soma-to-germline transition is a hallmark of human cancers
Mcfarlane, R. J., Feichtinger, J., Larcombe, L. & McFarlane, [. V., 15 May 2014, In: International Journal of Cancer. 134, 10, p. 2359-2365Research output: Contribution to journal › Article › peer-review