Dr Ramsay Mcfarlane
Uwch Ddarlithydd
Aelodaeth
Contact info
Location: Brambell, Room 405
Phone: 2360
Email: r.macfarlane@bangor.ac.uk
Position: Senior Lecturer / Research Group Leader / Deputy Head of School – Research
- Erthygl › Ymchwil › Adolygwyd gan gymheiriaid
- Cyhoeddwyd
5-azacytidine treatment of the fission yeast leads to cytotxicity and cell cycle arrest.
Taylor, E. M., Mcfarlane, R. & Price, C., 1996, Yn: Molecular Genetics and Genomics. 253, 1-2, t. 128-137Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets
Sammut, S. J., Feichtinger, J., Stuart, N. S., Wakeman, J., Larcombe, L. & Mcfarlane, R. J., 6 Mai 2014, Yn: Oncoscience. 1, 5, t. 349-359Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
A role for recombination in centromere function.
Mcfarlane, R. J., McFarlane, R. J. & Humphrey, T. C., 1 Mai 2010, Yn: Trends in Genetics. 26, 5, t. 209-213Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Biological roles of translin and translin-associated factor-X: RNA metabolism comes to the fore.
Mcfarlane, R. J., Jaendling, A. & McFarlane, R. J., 15 Gorff 2010, Yn: Biochemical Journal. 429, 2, t. 225-234Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer
Jezkova, J., Williams, J. S., Pinto, F., Sammut, S. J., Williams, G. T., Gollins, S., Mcfarlane, R. J., Reis, R. M. & Wakeman, J., 5 Chwef 2016, Yn: Oncotarget. 2016, 7, t. 11478-11486Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathway
Mcfarlane, R. J., Gollins, S. W., Wakeman, J., Jezkova, J., Williams, J. S., Jones-Hutchins, F., Sammut, S. J., Gollins, S., Cree, I., Coupland, S., McFarlane, R. J. & Wakeman, J. A., 21 Mai 2014, Yn: Oncotarget. 5, 11, t. 3813-3822Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Brachyury: Strategies for Drugging an Intractable Cancer Therapeutic Target
Robinson, H., McFarlane, R. J. & Wakeman, J. A., Ebr 2020, Yn: Trends in cancer. 6, 4, t. 271-273 3 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Cancer germline gene activation: Friend or foe?
Mcfarlane, R. J., McFarlane, R. J., Feichtinger, J. & Larcombe, L., 23 Meh 2014, Yn: Cell Cycle. 13, 14, t. 2151-2152Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Cancer/Testis Antigens and Colorectal Cancer
Sammut, S. J., Wakeman, J., Mcfarlane, R. J., Sammut, J., Wakeman, J. A., Stuart, N. & McFarlane, R. J., 13 Meh 2013, Yn: Journal of Genetic Syndromes and Gene Therapy. 4, 5, t. 149Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
CancerEST: a web-based tool for automatic meta-analysis of public EST data
Mcfarlane, R. J., Feichtinger, J., McFarlane, R. J. & Larcombe, L. D., 27 Chwef 2014, Yn: Database: The Journal of Biological Databases and Curation. 2014Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
CancerMA: a web-based tool for automatic meta-analysis of public cancer microarray data.
Feichtinger, J., Mcfarlane, R. & Larcombe, L., 15 Rhag 2012, Yn: Database: The Journal of Biological Databases and Curation. 2012, bas055.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function.
Mcfarlane, R., Carr, A. M. & Price, C., 1 Gorff 1997, Yn: Molecular Genetics and Genomics. 255, 3, t. 332-340Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Comparative proteomic analysis reveals differential expression of Hsp25 following the directed differentiation of mouse embryonic stem cells.
Wakeman, J., Mcfarlane, R. J., Battersby, A., Jones, R. D., Lilley, K. S., McFarlane, R. J., Braig, H. R., Allen, N. D. & Wakeman, J. A., 1 Chwef 2007, Yn: Biochimica et Biophysica Acta - Molecular Cell Research. 1773, 2, t. 147-156Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe.
Mcfarlane, R. J., Pryce, D. W., Lorenz, A., Smirnova, J. B., Loidl, J. & McFarlane, R. J., 1 Mai 2005, Yn: Genetics. 170, 1, t. 95-106Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX.
Mcfarlane, R. J., Jaendling, A., Ramayah, S., Pryce, D. W. & McFarlane, R. J., 1 Chwef 2008, Yn: Biochimica et Biophysica Acta - Molecular Cell Research. 1783, 2, t. 203-213Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Germline/meiotic genes in cancer: new dimensions
Mcfarlane, R. J., McFarlane, R. J., Feichtinger, J. & Larcombe, L., 19 Maw 2015, Yn: Cell Cycle. 14, 6, t. 791-792Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Homologous chromosome pairing in Schizosaccharomyces pombe
Mcfarlane, R. J., Wells, J. L., Pryce, D. W. & McFarlane, R. J., 15 Hyd 2006, Yn: Yeast. 23, 13, t. 977-989Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis
Planells Palop, V., Hazazi, A., Feichtinger, J., Jezkova, J., Thallinger, G. G., Alsiwiehri, N., Almutairi, M., Parry, L., Wakeman, J. & Mcfarlane, R., 26 Ebr 2017, Yn: Molecular Cancer. 16, 1, t. 1-18 84.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Identification of a class of human cancer germline genes with transcriptional silencing refractory to the hypomethylating drug 5-aza-2'-deoxycytidine
Almatrafi, A., Feichtinger, J., Vernon, E. G., Escobar, N. G., Wakeman, J. A., Larcombe, L. D. & McFarlane, R. J., 10 Tach 2014, Yn: Oncoscience. 1, 11, t. 745-750 6 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Linear element-independent meiotic recombination in Schizosaccharomyces pombe.
Mcfarlane, R. J., Wells, J. L., Pryce, D. W., Estreicher, A., Loidl, J. & McFarlane, R. J., 1 Tach 2006, Yn: Genetics. 174, 3, t. 1105-1114Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Meiosis-like functions in oncogenesis: a new view of cancer.
Mcfarlane, R. & Wakeman, J., Tach 2017, Yn: Cancer Research. 77, 21, t. 5712-5716Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Meiotic gene activation in somatic and germ cell tumours
Mcfarlane, R. & Feichtinger, J., Gorff 2019, Yn: Andrology. 7, 4, t. 415-427 13 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Meta-analysis of cancer microarray data sets reveals a germ line expression profile in ovarian cancers: new biomarkers and potential drug targets
Mcfarlane, R. J. & McFarlane, R., 15 Awst 2015, Yn: Clinical Cancer Research. 21, 16Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes.
Stuart, N. S., Wakeman, J., Mcfarlane, R. J., Feichtinger, J., Aldeailej, I., Anderson, R., Almutairi, M., Almatrafi, A., Alsiwiehri, N., Griffiths, K., Stuart, N., Wakeman, J. A., Larcombe, L. & McFarlane, R. J., 13 Awst 2012, Yn: Oncotarget. 3, 8, t. 843-853Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Meta-analysis of expression of l(3)mbt tumor-associated germline genes supports the model that a soma-to-germline transition is a hallmark of human cancers
Mcfarlane, R. J., Feichtinger, J., Larcombe, L. & McFarlane, [. V., 15 Mai 2014, Yn: International Journal of Cancer. 134, 10, t. 2359-2365Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis.
Jessen, J. R., Meng, A., Mcfarlane, R., Paw, B. H., Zon, L. I., Smith, G. R. & Lin, S., 1998, Yn: Proceedings of the National Academy of Sciences of the USA. 95, 9, t. 5121 5126 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Molecular mechanisms of intramolecular recombination-dependent recircularization of linearized plasmid DNA in Escherichia coli: requirements for ruvA, ruvB, recG, recF and recR gene products.
Mcfarlane, R. & Saunders, J. R., 1996, Yn: Gene. 177, 1-2, t. 209-216Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Psc3 cohesion of Schizosaccharomyces pombe: cell cycle analysis and identification of three distinct isoforms
Ilyushik, E., Pryce, D., Walerych, D., Riddell, T., Wakeman, J. A., McInerny, C. J. & Mcfarlane, R., Gorff 2005, Yn: Biological Chemistry. 386, 7, t. 613-621Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Recombination at DNA replication fork barriers is not universal and is differentially regulated by Swi1
Pryce, D. W., Ramayah, S., Jaendling, A. & Mcfarlane, R., 24 Maw 2009, Yn: Proceedings of the National Academy of Sciences of the USA. 106, 12, t. 4770-4775Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
S-pombe meiotic linear elements contain proteins related to synaptonemal complex components
Lorenz, A., Wells, J. L., Pryce, D., Novatchkova, M., Eisenhaber, F., Mcfarlane, R. J. & Loidl, J., 28 Meh 2004, Yn: Journal of Cell Science. 117, 15, t. 3343-3351Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
SUMOylation is required for normal development of linear elements and wild-type meiotic recombination in Schizosaccharomyces pombe.
Mcfarlane, R. J., Spirek, M., Estreicher, A., Csaszar, E., Wells, J., McFarlane, R. J., Watts, F. Z. & Loidl, J., 1 Chwef 2010, Yn: Chromosoma. 119, 1, t. 59-72Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
The Meiotic Recombination Hotspots of Schizosaccharomyces pombe
Pryce, D. & Mcfarlane, R. J., 1 Ion 2009, Yn: Meiosis. 5, t. 1-13Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
The genetics of the repaor of 5-azacytidine-mediated DNA damage in the fission yeast Schizosaccharomyces pombe.
Hegde, V., Mcfarlane, R., Taylor, E. M. & Price, C., 1 Meh 1996, Yn: Molecular Genetics and Genomics. 251, 4, t. 483-492Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
The immortal strand hypothesis: still non-randomly segregating opinion.
Wakeman, J., Hmadcha, A., Soria, B. & Mcfarlane, R., 23 Maw 2012, Yn: Biomolecular Concepts. 3, 3, t. 203-211Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
The many facets of the Tim-Tipin protein families' roles in chromosome biology.
Mcfarlane, R. J., McFarlane, R. J., Mian, S. & Dalgaard, J. Z., 15 Chwef 2010, Yn: Cell Cycle. 9, 4, t. 700-705Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
The unique centromeric chromatin structure of Schizosaccharomyces pombe is maintained during meiosis.
Mcfarlane, R. J., Smirnova, J. B. & McFarlane, R. J., 31 Mai 2002, Yn: Journal of Biological Chemistry. 277, 22, t. 19817-19822Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Translin and Trax differentially regulate telomere-associated transcript homeostasis
Gomez Escobar, N., Almobadel, N., Alzahrani, O., Feichtinger, J., Planells Palop, V., Alshehri, Z., Thallinger, G. G., Wakeman, J. & Mcfarlane, R., 10 Mai 2016, Yn: Oncotarget. 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Translin facilitates RNA polymerase II dissociation and suppresses genome instability during RNase H2- and Dicer-deficiency
Gomez Escobar, N., Alsaiari, A., Alahmadi, H. A. S., Alzahrani, O., Vernon, E., Althagafi, H., Almobadel, N., Pryce, D., Wakeman, J. & Mcfarlane, R., 17 Meh 2022, Yn: PLOS Genetics. 18, 6, e1010267.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Translin-Trax: Considerations for Oncological Therapeutic Targeting
McFarlane, R. J. & Wakeman, J. A., Meh 2020, Yn: Trends in Cancer. 6, 6, t. 450-453 4 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
tRNA genes in eukaryotic genome organization and reorganization.
Mcfarlane, R. J., McFarlane, R. J. & Whitehall, S. K., 1 Hyd 2009, Yn: Cell Cycle. 8, 19, t. 3102-3106Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid