Dr Anita Malhotra
Reader in Zoology (Molecular Ecology)
Affiliations
Postal address
Contact info
My research interests focus on the role of natural selection in population adaptation and divergence, to which I apply a wide range of methods including multivariate morphometrics, statistical hypothesis-testing, innovative field experiments and genome analysis. I have two main areas of research on disparate organisms in different geographical regions (Anolis lizards in the Caribbean and Asian pit vipers), which are unified by being essentially focussed on the interface between evolution and ecology, and with an emphasis on the integration of genetic and phenetic data. More recently, my research has moved into the field of ecological and evolutionary genomics to evaluate the evolution of genes affecting complex traits directly and relies on the availability of a well-supported and complete organismal phylogeny of Asian pitvipers generated by my students and myself. Drawing on numerous collaborations to bring together disparate strands of organismal biology and ecology, evolutionary theory, comparative genomics, bioinformatics and proteomics, I aim to develop an integrated picture of the evolution of snake venom components.
Another strand to this research on venomous snakes involves snakebite mitigation, and I am currently involved in several projects in India, dubbed the "snakebite capital of the world", where c. 50,000 people die from snakebite every year and many more suffer permanent disability. Together with partners in India, our work ranges from mapping the distribution and genetic and venom variation present in venomous species across the country, to undertaking rescuer training and education and awareness programs. We are particularly focussing on the Himalayan and northeastern region, which belong to biodiversity "hotspots" but are relatively understudied. The venomous species in these regions are diferent to the rest of the country, and are not covered by the currently available polyvalent antivenom.
I am also involved in research on the genetic health of honeybees and other pollinators, together with colleague Dr Paul Cross. We are part of the recently formed research network on British dark bee conservation that includes researchers from Plymouth University, National University of Ireland (Galway), and the University of Edinburgh.
- Article › Research › Peer-reviewed
- Published
A paper microfluidic device based colorimetric sensor for the detection and discrimination of elapid versus viper envenomation
Ramana, L., Mathapati, S. S., Salvi, N., Khadilkar, M. V., Malhotra, A., Santra, V. & Sharma, T. K., 21 Feb 2022, In: Analyst. 147, 4, p. 685-694Research output: Contribution to journal › Article › peer-review
- Published
A phylogenetic analysis of body size evolution in the Anolis roquet group (Sauria : Iguanidae): character displacement or size assortment?
Giannasi, N., Thorpe, R. S. & Malhotra, A., 1 Feb 2000, In: Molecular Ecology. 9, 2, p. 193-202Research output: Contribution to journal › Article › peer-review
- Published
A phylogeny of four mitochondrial gene regions suggests a revised taxonomy for Asian pitvipers (Trimeresurus and Ovophis).
Malhotra, A. & Thorpe, R. S., 1 Jul 2004, In: Molecular Phylogenetics and Evolution. 32, 1, p. 83-100Research output: Contribution to journal › Article › peer-review
- Published
A phylogeny of the Trimeresurus group of pit vipers: New evidence from a mitochondrial gene tree.
Malhotra, A. & Thorpe, R. S., 1 Aug 2000, In: Molecular Phylogenetics and Evolution. 16, 2, p. 199-211Research output: Contribution to journal › Article › peer-review
- Published
Adaptive radiation in Lesser Antillean lizards: molecular phylogenetics and species recognition in the Lesser Antillean dwarf gecko complex, Sphaerodactylus fantasticus.
Thorpe, R. S., Jones, A. G., Malhotra, A. & Surget-Groba, Y., 1 Mar 2008, In: Molecular Ecology. 17, 6, p. 1489-1504Research output: Contribution to journal › Article › peer-review
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An evaluation of the systematic value of skull morphology in the Trimeresurus radiation (Serpentes: Viperidae: Crotalinae) of Asian pitvipers.
Guo, P., Malhotra, A., Creer, S. & Pook, C. E., 1 Nov 2009, In: Journal of Zoological Systematics and Evolutionary Research. 47, 4, p. 378-384Research output: Contribution to journal › Article › peer-review
- Published
Assessing the phylogenetic utility of four mitochondrial genes and a nuclear intron in the Asian pit viper genus, Trimeresurus: Separate, simultaneous, and conditional data combination analyses
Creer, S., Malhotra, A. & Thorpe, R. S., 1 Aug 2003, In: Molecular Biology and Evolution. 20, 8, p. 1240-1251Research output: Contribution to journal › Article › peer-review
- Published
Bungarus fasciatus venom from eastern and north-east India: venom variation and immune cross-reactivity with Indian polyvalent antivenoms
Talukdar, A., Malhotra, A., Lalremsanga, H. T., Santra, V. & Doley, R., Mar 2023, In: Journal of Proteins and Proteomics. 14, 1, p. 61-76Research output: Contribution to journal › Article › peer-review
- Published
Colonization history and genetic diversity: adaptive potential in early stage invasions.
Eales, J. F., Thorpe, R. S. & Malhotra, A., 1 Jul 2010, In: Molecular Ecology. 19, 14, p. 2858-2869Research output: Contribution to journal › Article › peer-review
- Published
Combining molecular, morphological and ecological data to infer species boundaries in a cryptic tropical pitviper.
Sanders, K. L., Malhotra, A. & Thorpe, R. S., 1 Mar 2006, In: Biological Journal of the Linnean Society. 87, 3, p. 343-364Research output: Contribution to journal › Article › peer-review
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Comments on the systematic status of specimens belonging to the genus Viridovipera (Serpentes: Viperidae: Crotalinae) from Sichuan and Yunnan provinces of southwestern China, with a redescription of V. yunnanensis.
Guo, P., Malhotra, A., Thorpe, R. S., Creer, S. & Pook, C. E., 1 Jul 2009, In: Herpetological Journal. 19, 3, p. 151-162Research output: Contribution to journal › Article › peer-review
- Published
Common garden and natural selection experiments support ecotypic differentiation in the Dominican anole (Anolis oculatus).
Thorpe, R. S., Reardon, J. T. & Malhotra, A., 1 Apr 2005, In: American Naturalist. 165, 4, p. 495-504Research output: Contribution to journal › Article › peer-review
- Published
Complex target SELEX-based identification of DNA aptamers against Bungarus caeruleus venom for the detection of envenomation using a paper-based device
Anand, A., Chatterjee, B., Dhiman, A., Goel, R., Khan, E., Malhotra, A., Santra, V., Salvi, N., Bhatnagar, I., Kumar, A., Asthana, A. & Sharma, T. K., 1 Dec 2021, In: Biosensors and Bioelectronics. 193, 113523.Research output: Contribution to journal › Article › peer-review
- Published
Confirmation of Liopeltis rappi (Günther, 1860) in Himachal Pradesh
Kuttalam, S. R., Santra, V., Owens, J. B., Ahmed, M. T., Bharti, O., Selvan, M., Mukherjee, N. & Malhotra, A., Oct 2022, In: Hamadryad. 39, 1-2, p. 85-88Research output: Contribution to journal › Article › peer-review
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Confirmation of Naja oxiana in Himachal Pradesh, India
Santra, V., Owens, J. B., Graham, S., Wüster, W., Kuttalam, S. R., Bharti, O., Selvan, M., Mukherjee, N. & Malhotra, A., 1 Dec 2019, In: Herpetological Bulletin. 150, p. 26-28Research output: Contribution to journal › Article › peer-review
- Published
Convergence of multiple markers and analysis methods defines the genetic distinctiveness of cryptic pitvipers
Mrinalini, M., Thorpe, R. S., Creer, S., Lallias, D. S., Dawnay, L., Stuart, B. L. & Malhotra, A., 8 Jul 2015, In: Molecular Phylogenetics and Evolution. 92, p. 266-279Research output: Contribution to journal › Article › peer-review
- Published
Ecological diversification in a group of Indomalayan pitvipers (Trimeresurus): convergence in taxonomically important traits has implications for species identification.
Sanders, K. L., Malhotra, A. & Thorpe, R. S., 1 Jul 2004, In: Journal of Evolutionary Biology. 17, 4, p. 721-731Research output: Contribution to journal › Article › peer-review
- Published
Estimating genetic variability in non-model taxa: a general procedure for discriminating sequence errors from actual variation.
Dawson, K., Thorpe, R. S. & Malhotra, A., 6 Dec 2010, In: PLoS ONE. 15, 12, p. e15204Research output: Contribution to journal › Article › peer-review
- Published
Evidence for a Mullerian mimetic radiation in Asian pitvipers
Sanders, K. L., Malhotra, A. & Thorpe, R., 7 May 2006, In: Proceedings of The Royal Society B - Biological Sciences. 273, 1590, p. 1135-1141Research output: Contribution to journal › Article › peer-review
- Published
Evolutionary differentiation of bimaculatus group anoles based on analyses of mtDNA and microsatellite data.
Stenson, A. G., Thorpe, R. S. & Malhotra, A., 1 Jul 2004, In: Molecular Phylogenetics and Evolution. 32, 1, p. 1-10Research output: Contribution to journal › Article › peer-review
- Published
Genetic and ecological correlates of intraspecific variation in pitviper venom composition detected using matirx-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF-MS) and isoelectric focusing
Creer, S., Malhotra, A., Thorpe, R., Stocklin, R. S., Favreau, P. S. & Chou, W. S., 1 Mar 2003, In: Journal of Molecular Evolution. 56, 3, p. 317-329Research output: Contribution to journal › Article › peer-review
- Published
Inclusion of nuclear intron sequence data helps to identify the Asian sister group of New World pitvipers.
Malhotra, A., Creer, S., Pook, C. E. & Thorpe, R. S., 1 Jan 2010, In: Molecular Phylogenetics and Evolution. 54, 1, p. 172-178Research output: Contribution to journal › Article › peer-review
- Published
Maximizing information in systematic revisions: a combined molecular and morphological analysis of a cryptic green pitviper complex (Trimeresurus stejnegeri).
Malhotra, A. & Thorpe, R. S., 1 Jun 2004, In: Biological Journal of the Linnean Society. 82, 2, p. 219-235Research output: Contribution to journal › Article › peer-review
- Published
Mitochondrial DNA analysis reveals a new member of the Asian pitviper genus Viridovipera (Serpentes: Viperidae: Crotalinae).
Dawson, K., Malhotra, A., Thorpe, R. S., Guo, P., Mrinalini, [. V. & Ziegler, T., 1 Oct 2008, In: Molecular Phylogenetics and Evolution. 49, 1, p. 356-361Research output: Contribution to journal › Article › peer-review
- Published
Molecular phylogenetic analysis of the genus Gloydius (Squamata, Viperidae, Crotalinae), with description of two new alpine species from Qinghai-Tibet Plateau, China
Shi, J.-S., Liu, J.-C., Giri, R., Owens, J. B., Santra, V., Kuttalam, S. R., Selvan, M., Guo, K.-J. & Malhotra, A., 4 Oct 2021, In: ZooKeys. 1061, 1061, p. 87-108 22 p.Research output: Contribution to journal › Article › peer-review
- Published
Molecular phylogeny reveals distinct evolutionary lineages of the banded krait, Bungarus fasciatus (Squamata, Elapidae) in Asia
Biazkula, L., Lalremsanga, H., Santra, V., Dhara, A., Ahmed, M. T., Mallick, Z., Kuttalam, S. R., Amarasinghe, A. A. T. & Malhotra, A., 4 Feb 2023, In: Scientific Reports. 13, 1, 14 p., 2061.Research output: Contribution to journal › Article › peer-review
- Published
Molecular phylogeography of Jerdon’s pitviper (Protobothrops jerdonii): importance of the uplift of the Tibetan plateau
Guo, P., Liu, Q., Li, C., Chen, X., Jiang, K., Wang, Y. Z. & Malhotra, A., 1 Dec 2011, In: Journal of Biogeography. 38, 12, p. 2326–2336Research output: Contribution to journal › Article › peer-review
- Published
Morphometric analysis of Trimeresurus vogeli (David, Vidal and Pauwels, 2001), with new data on diagnostic characteristics, distribution and natural history.
Malhotra, A., Thorpe, R. S. & Stuart, B. L., 1 Apr 2004, In: Herpetological Journal. 14, 2, p. 65-77Research output: Contribution to journal › Article › peer-review
- Published
Multilevel comparison of Indian Naja venoms and their cross-reactivity with Indian polyvalent antivenoms
Deka, A., Bhatia, S., Santra, V., Bharti, O., Lalremsanga, H., Martin, G., Wüster, W., Owens, J. B., Graham, S., Doley, R. & Malhotra, A., 1 Apr 2023, In: Toxins. 15, 4, 24 p.Research output: Contribution to journal › Article › peer-review
- Published
Multilocus phylogeny, species age and biogeography of the Lesser Antillean anoles
Thorpe, R., Barlow, A., Surget-Groba, Y. & Malhotra, A., Oct 2018, In: Molecular Phylogenetics and Evolution. 127, p. 682-695Research output: Contribution to journal › Article › peer-review
- Published
Multilocus phylogeography of the brown-spotted pitviper Protobothrops mucrosquamatus (Reptilia: Serpentes: Viperidae) sheds a new light on the diversification pattern in Asia
Guo, P., Liu, Q., Zhu, F., Zhong, G. H., Che, J., Wang, P., Xie, Y. L., Murphy, R. W. & Malhotra, A., Apr 2019, In: Molecular Phylogenetics and Evolution. 133, p. 82-91Research output: Contribution to journal › Article › peer-review
- Published
Multiple causation of phylogeographical pattern as revealed by nested clade analysis of the bamboo viper (Trimeresurus stejnegeri) within Taiwan.
Creer, S., Malhotra, A., Thorpe, R. S. & Chou, W. H., 1 Aug 2001, In: Molecular Ecology. 10, 8, p. 1967-1981Research output: Contribution to journal › Article › peer-review
- Published
Nuclear and mtDNA phylogenies of the Trimeresurus complex: Implications for the gene versus species tree debate.
Giannasi, N., Malhotra, A. & Thorpe, R. S., 1 Apr 2001, In: Molecular Phylogenetics and Evolution. 19, 1, p. 57-66Research output: Contribution to journal › Article › peer-review
- Published
Offshore insular variation in the diet of the Taiwanese bamboo viper Trimeresurus stejnegeri (Schmidt)
Creer, S., Chou, W. H., Malhotra, A. & Thorpe, R. S., 1 Aug 2002, In: Zoological Science. 19, 8, p. 907-913Research output: Contribution to journal › Article › peer-review
- Published
Optimal intron analyses in the Trimeresurus radiation of Asian pitvipers.
Creer, S., Pook, C. E., Malhotra, A. & Thorpe, R. S., 1 Feb 2006, In: Systematic Biology. 55, 1, p. 57-72Research output: Contribution to journal › Article › peer-review
- Published
Phylogenetic and morphological analysis of Gloydius himalayanus (Serpentes, Viperidae, Crotalinae), with the description of a new species
Kuttalam, S. R., Santra, V., Owens, J. B., Selvan, M., Mukherjee, N., Graham, S., Togridou, A., Bharti, O., Shi, J., Shanker, K. & Malhotra, A., 13 Dec 2022, In: European Journal of Taxanomy. 852, 1, p. 1-30 30 p., 1.Research output: Contribution to journal › Article › peer-review
- Published
Phylogenetic structure and species boundaries in the mountain pitviper Ovophis monticola (Serpentes: Viperidae: Crotalinae) in Asia.
Malhotra, A., Dawson, K., Guo, P. & Thorpe, R. S., 1 May 2011, In: Molecular Phylogenetics and Evolution. 59, 2, p. 444-457Research output: Contribution to journal › Article › peer-review
- Published
Phylogeography and natural selection in the Tenerife gecko Tarentola delalandii: testing historical and adaptive hypotheses.
Gubitz, T., Thorpe, R. S. & Malhotra, A., 1 Sept 2000, In: Molecular Ecology. 9, 9, p. 1213-1221Research output: Contribution to journal › Article › peer-review
- Published
Population differentiation and nuclear gene flow in the Dominican anole (Anolis oculatus).
Stenson, A. G., Malhotra, A. & Thorpe, R. S., 1 Sept 2002, In: Molecular Ecology. 11, 9, p. 1679-1688Research output: Contribution to journal › Article › peer-review
- Published
Predicting function from sequence in a large multifunctional toxin family
Malhotra, A., Creer, S., Harris, J. B., Stöcklin, R., Favereau, P. & Thorpe, R. S., 3 Jul 2013, In: Toxicon. 72, p. 113-125Research output: Contribution to journal › Article › peer-review
- Published
Prevention is better than cure : snakebite education in India
Trogridou, A., Graham, S., Santra, V., Owens, J. B., Bharti, O. & Malhotra, A., 2019, In: Episthmes Agogis . p. 75-96Research output: Contribution to journal › Article › peer-review
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Promoting co-existence between humans and venomous snakes through increasing the herpetological knowledge base
Malhotra, A., Wüster, W., Owens, J. B., Hodges, C. W., Jesudasan, A., Ch, G., Kartik, A., Christopher, P., Louies, J., Naik, H., Santra, V., Kuttalam, S. R., Attre, S., Sasa, M., Bravo-Vega, C. & Murray, K. A., 1 Nov 2021, In: Toxicon: X. 12, November 2021, 18 p., 10081.Research output: Contribution to journal › Article › peer-review
- Published
Rational truncation of aptamer for cross-species application to detect krait envenomation
Dhiman, A., Anand, A., Malhotra, A., Khan, E., Santra, V., Kumar, A. & Sharma, T. K., 12 Dec 2018, In: Scientific Reports. 8, 17795.Research output: Contribution to journal › Article › peer-review
- Published
Reassessment of the validity and diagnosis of the pitviper Trimeresurus venustus Vogel, 1991.
Malhotra, A. & Thorpe, R. S., 1 Jan 2004, In: Herpetological Journal. 14, 1, p. 21-33Research output: Contribution to journal › Article › peer-review
- Published
Redescription and systematics of trimeresurus cornutus (Serpentes : Viperidae) based on morphology and molecular data.
Herrmann, H. W., Ziegler, T., Malhotra, A., Thorpe, R. & Parkinson, C. L., 1 May 2004, In: Herpetologica. 60, 2, p. 211-221Research output: Contribution to journal › Article › peer-review
- Published
Systematics and biogeography of snakes of the genus Boa in the Lesser Antilles
Thorpe, R. & Malhotra, A., 20 Sept 2023, In: Caribbean Herpetology. 88, 88, p. 1-14 14 p., 88.Research output: Contribution to journal › Article › peer-review
- Published
Systematics of the Protobothrops jerdonii complex (Serpentes, Viperidae, Crotalinae) inferred from morphometric data and molecular phylogeny.
Guo, P., Malhotra, A., Li, C., Creer, S., Pook, P. E. & Wen, T., 1 Jul 2009, In: Herpetological Journal. 19, 2, p. 85-96Research output: Contribution to journal › Article › peer-review
- Published
Tackling Snakebite Through Training: an Indian example
Malhotra, A., Graham, S., Owens, J. B., Bharti, O. & Santra, V., 31 Aug 2022, In: Herpetological Conservation and Biology. 17, 2, p. 331–342Research output: Contribution to journal › Article › peer-review
- Published
Targeting optimal introns for phylogenetic analyses in non-model taxa: experimental results in Asian pitvipers.
Creer, S., Malhotra, A., Thorpe, R. S. & Pook, C. E., 1 Aug 2005, In: Cladistics. 21, 4, p. 390-395Research output: Contribution to journal › Article › peer-review
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The conservation status of the world’s reptiles
Böhm, M., Collen, B., Baillie, J. E., Bowles, P., Chanson, J., Cox, N., Hammerson, G., Hoffmann, M., Livingstone, S. R., Ram, M., Rhodin, A. G., Stuart, S. N., van Dijk, P. P., Young, B. E., Afuang, L. E., Aghasyan, A., García, A., Aguilar, C., Ajtic, R., Akarsu, F., Alencar, L. R., Allison, A., Ananjeva, N., Anderson, S., Andrén, C., Ariano-Sánchez, D., Arredondo, J. C., Auliya, M., Austin, C. C., Avci, A., Baker, P. J., Barreto-Lima, A. F., Barrio-Amorós, C. L., Basu, D., Bates, M. F., Batistella, A., Bauer, A., Bennett, D., Böhme, W., Broadley, D., Brown, R., Burgess, J., Captain, A., Carreira, S., del Rosario Castañeda, M., Castro, F., Catenazzi, A., Cedeño-Vázquez, J. R., Chapple, D. G., Cheylan, M., Cisneros-Heredia, D. F., Cogalniceanu, D., Cogger, H., Corti, C., Costa, G. C., Couper, P. J., Courtney, T., Crnobrnja-Isailovic, J., Crochet, P. A., Crother, B., Cruz, F., Daltry, J. C., Daniels, R. J., Das, A., de Silva, A., Diesmos, A. C., Dirksen, L., Doan, T. M., Dodd Jr., C. K., Doody, J. S., Dorcas, M. E., de Barros Filho, J. D., Egan, V. T., El Mouden, E. H., Embert, D., Espinoza, R. E., Fallabrino, A., Feng, X., Feng, S. J., Fitzgerald, L., Flores-Villela, O., França, F. G., Frost, D., Gadsden, H., Gamble, T., Ganesh, S. R., Garcia, M. A., García-Pérez, J. E., Gatuscm, J., Gaulke, M., Geniez, P., Georges, A., Gerlach, J., Goldberg, S., Gonzale, J. C., Gower, D. J., Grant, T., Greenbaum, E., Grieco, C., Guo, P., Hamilton, A. M., Hare, K., Hedges, S. B., Heideman, N., Hilton-Taylor, C., Hitchmough, R., Hollingsworth, B., Hutchinson, M., Ineich, I., Iverson, J., Jaksic, F. M., Jenkins, R., Joger, U., Jose, R., Kaska, Y., Kaya, U., Keogh, J. S., Köhler, G., Kuchling, G., Kumlutaş, Y., Kwet, A., La Marca, E., Lamar, W., Lane, A., Lardner, B., Latta, C., Latta, G., Lau, M., Lavin, P., Lawson, D., LeBreton, M., Lehr, E., Limpus, D., Malhotra, A. & et al., [. V., 1 Jan 2013, In: Biological Conservation. 157, p. 372-385Research output: Contribution to journal › Article › peer-review