Dyfrig Hughes - Research outputs

Published

‘Seizure First Aid Training’ for people with epilepsy who attend emergency departments, and their family and friends: study protocol for intervention development and a pilot randomised controlled trial

Noble, A. J., Marson, A. G., Tudur-Smith, C., Morgan, M., Hughes, D., Goodacre, S. & Ridsdale, L., 24 Jul 2015, In: BMJ Open. 5, 7

Research output: Contribution to journal › Article › peer-review

Published

When drugs don't work - Economic assessment of enhancing compliance with interventions supported by electronic monitoring devices.

Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Pharmacoeconomics. 25, 8, p. 621-635

Research output: Contribution to journal › Article › peer-review

Published

What should patients do if they miss a dose? A systematic review of patient information leaflets and summaries of product characteristics

Albassam, A. & Hughes, D., Feb 2021, In: European Journal of Clinical Pharmacology. 77, 2, p. 251-260 10 p.

Research output: Contribution to journal › Article › peer-review

Published

What really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK

Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Jun 2019, In: Epilepsy and Behavior. 95, p. 181-191

Research output: Contribution to journal › Article › peer-review

Published

What is the long-term impact of COVID-19 on the Health-Related Quality of Life of individuals with mild symptoms (or non-hospitalised): A rapid review

Spencer, L., Hendry, A., Makanjuola, A., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 9 Sept 2022, Health and Care Research Wales, 47 p.

Research output: Working paper › Preprint

Published

What is the effectiveness and cost-effectiveness of interventions in reducing the harms for children and young people who have been exposed to domestic violence or abuse: a rapid review.

Spencer, L., Hendry, A., Makanjuola, A., Pisavadia, K., Davies, J., Albustami, M., Anthony, B., Wilkinson, C., Fitzsimmons, D., Hughes, D., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 10 May 2023, 79 p.

Research output: Book/Report › Commissioned report

Published

What interventions or best practice are there to support people with Long COVID, or similar post-viral conditions or conditions characterised by fatigue, to return to normal activities: a rapid review

Spencer, L., Hendry, A., Makanjuola, A., Anthony, B., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 28 Jan 2023, 34 p. (MedRxiv).

Research output: Working paper › Preprint

Published

What innovations can address inequalities experienced by women and girls due to the COVID-19 pandemic across the different areas of life/domains: work, health, living standards, personal security, participation and education? Report number – RR00027 (January 2022). Gender Inequalities: COVID-19 initiatives

Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Pisavadia, K., Davies, J., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 15 Jan 2022, Health and Care Research Wales.

Research output: Book/Report › Commissioned report › peer-review

Published

What influences persistence with medicines? A multinational discrete choice experiment of 2549 patients

Holmes, E. A., Morrison, V. L. & Hughes, D., Aug 2016, In: British Journal of Clinical Pharmacology. 82, 2, p. 522-531

Research output: Contribution to journal › Article › peer-review

Published

What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?

Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Welsh Health Economics Network (WHEN): Scoping Report.

Hughes, D., Farr, A., O Ceilleachair, A., Cohen, D., Hughes, D. A. & Phillips, C., 1 Jan 2005, 2005 ed. Unknown.

Research output: Book/Report › Commissioned report

E-pub ahead of print

We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment

Hughes, D., 27 Sept 2023, (E-pub ahead of print) In: Health Economics, Policy and Law.

Research output: Contribution to journal › Article › peer-review

Published

Warfarin pharmacogenetics: Economic considerations.

Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Jan 2007, In: Pharmacoeconomics. 25, 11, p. 899-902

Research output: Contribution to journal › Article › peer-review

Published

Value-Based Pricing: Incentive for Innovation or Zero Net Benefit?

Hughes, D. & Hughes, D. A., 1 Sept 2011, In: Pharmacoeconomics. 29, 9, p. 731-735

Research output: Contribution to journal › Article › peer-review

Published

Value of improving patient safety: Health-economic considerations for Rapid Response Systems – a Rapid Review of the Literature and Expert Round Table

Subbe, C., Hughes, D., Lewis, S., Holmes, E., Kalkman, C. J., So, R. K., Tranka, S. & Welch, J., 17 Apr 2023, In: BMJ Open. 13, 4, e065819.

Research output: Contribution to journal › Article › peer-review

Published

Value assessment and quantitative benefit-risk modelling of biosimilar infliximab for Crohn’s disease

Catt, H., Bodger, K., Hughes, D. & Kirkham, J. J., Dec 2019, In: PharmacoEconomics. 37, 12, p. 1509-1523 15 p.

Research output: Contribution to journal › Article › peer-review

Published

Valuations of epilepsy-specific health states: a comparison of patients with epilepsy and the general population

Hughes, D., Mulhern, B., Rowen, D., Snape, D., Jacoby, A., Marson, T., Hughes, D. A., Baker, G. & Brazier, J., 1 Jul 2014, In: Epilepsy and Behavior. 36, p. 12-17

Research output: Contribution to journal › Article › peer-review

Published

Utilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project

Totton, N., Julious, S., Hughes, D., Cook, J., Biggs, K., Coates, L., Cook, A., Hewitt, C. & Day, S., 19 Jan 2021, In: Trials. 22, 68.

Research output: Contribution to journal › Article › peer-review

Published

Using Routinely Recorded Data in the UK to Assess Outcomes in a Randomised Controlled Trial: The Trials of Access

Powell, G., Bonnett, L., Smith, C. T., Hughes, D., Williamson, P. & Marson, A., 23 Aug 2017, In: Trials. 18, 11 p., 389.

Research output: Contribution to journal › Article › peer-review

Published

Using Routinely Recorded Data in a UK RCT: A Comparison to Standard Prospective Data Collection Methods

Powell, G., Bonnett, L., Tudor-Smith, C., Hughes, D., Williamson, P. R. & Marson, A. G., 5 Jul 2021, In: Trials. 22, 1, 429.

Research output: Contribution to journal › Article › peer-review

Published

Use of PK-PD modelling to predict the impact of non-compliance

Hughes, D. & Hughes, D. A., 1 Nov 2003.

Research output: Contribution to conference › Paper

Published

Use Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients

Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A580

Research output: Contribution to journal › Article › peer-review

Published

Understanding medication compliance and persistence from an economics perspective

Hughes, D., Elliot, R. A., Shinogle, J. A., Peele, P., Bhosle, M. & Hughes, D. A., 1 Jan 2008, In: Value in Health. 11, 4, p. 600-610

Research output: Contribution to journal › Article › peer-review

Published

Ultra-long acting pharmaceuticals: Do they result in better outcomes, and at an acceptable cost?

Hughes, D. & Hughes, D. A., 1 Nov 2006.

Research output: Contribution to conference › Paper

Published

Trends and influences on use of antidiabetic drugs in England, 1992-2003.

Walley, T., Hughes, D. & Kendall, H., 1 Nov 2005, In: Pharmacoepidemiology and Drug Safety. 14, 11, p. 769-773

Research output: Contribution to journal › Article › peer-review

Published

The role of prevention in reducing the economic impact of ME/CFS in Europe: A report from the socioeconomics working group of the European Network on ME/CFS (EUROMENE).

Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 16 Apr 2021, In: Medicina. 57, 4, 388.

Research output: Contribution to journal › Article › peer-review

Published

The problem of orphan drugs

Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Nov 2010, In: British Medical Journal. 341, p. 335-341

Research output: Contribution to journal › Article › peer-review

Published

The population pharmacokinetics of lapdap

Hughes, D., Ward, S., Simpson, J., Aarons, L., Szwandt, S. & Hughes, D. A., 1 Nov 2002.

Research output: Contribution to conference › Paper

Published

The pharmacokinetic profile of Warfarn: a systematic review

Hughes, D., Al-Zubiedi S.*, N. V., Hughes D.A., N. V. & Pirmohamed, M., 1 Dec 2007.

Research output: Contribution to conference › Paper

Published

The new and non-transparent Cancer Drugs Fund

Wood, E. & Hughes, D., Jan 2020, In: PharmacoEconomics. 38, 1, p. 1-4

Research output: Contribution to journal › Article › peer-review

Published

The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies.

Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies

Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Jan 2000, In: Value in Health. 3, 5, p. 373

Research output: Contribution to journal › Article › peer-review

Published

The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies

Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Nov 2000.

Research output: Contribution to conference › Paper

Published

The impact of parent treatment preference and other factors on recruitment: lessons learned from a paediatric epilepsy randomised controlled trial

Carter, B., Bray, L., Al-Najjar, N., Tort Piella, A., Smith, C. T., Spowart, C., Collingwood, A., Crudgington, H., Currier, J., Hughes, D., Wood, E., Martin, R., Morris, C., Roberts, D., Rouncefield-Swales, A., Sutherland, H., Watson, V., Cook, G., Wiggs, L., Gringas, P. & Pal, D., 6 Feb 2023, In: Trials. 24, 1, 83.

Research output: Contribution to journal › Article › peer-review

Published

The impact of non-compliance on the cost-effectiveness of pharmaceuticals: A review of the literature.

Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Oct 2001, In: Health Economics. 10, 7, p. 601-615

Research output: Contribution to journal › Article › peer-review

Published

The future challenges

Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 167-174

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Published

The experiences and perspectives of people with gout on urate self-monitoring

Michael, T. J. F., Chan, J. S., Hughes, S., Wright, D. F. B., Coleshill, M. J., Hughes, D., Day, R. O., Aslani, P. & Stocker, S. L., Jun 2024, In: Health Expectations. 27, 3, 9 p., e14071.

Research output: Contribution to journal › Article › peer-review

Published

The effect of compliance upon clinical effectiveness of chlorproguanil-dapsone (CD) and artemether-lumefantrine (AL) when compared to sulfadoxine-pyrimethamine (SP) for the treatment of uncomplicated falcipaum malaria in Malawi - a randomised controlled trial

Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Zijlstra, E., Hughes D.A., N. V., Molyneux M.E.*, N. V., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 1 Nov 2007.

Research output: Contribution to conference › Paper

Published

The economics of evergreening.

Hughes, D. & Hughes, D. A., 1 Jan 2009.

Research output: Contribution to conference › Paper

Published

The difference between effectiveness and efficacy of antimalarial drugs in Kenya.

Hughes, D., Amin, A. A., Hughes, D. A., Marsh, V., Abuya, T. O., Kokwaro, G. O., Winstanley, P. A., Ochala, S. A. & Snow, R. W., 1 Sept 2004, In: Tropical Medicine and International Health. 9, 9, p. 967-974

Research output: Contribution to journal › Article › peer-review

Published

The development of a QALY measure for epilepsy: NEWQOL-6D

Hughes, D., Mulhern, B., Rowen, D., Jacoby, A., Marson, T., Snape, D., Hughes, D. A., Latimer, N., Baker, G. A. & Brazier, J. E., 1 May 2012, In: Epilepsy and Behavior. 24, 1, p. 36-43

Research output: Contribution to journal › Article › peer-review

Published

The costs and cost-effectiveness of different service models of palliatice care, focusing on end of life care: A rapid review

Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Gillen, E., Noyes, J., Fitzsimmons, D., Lewis, R., Cooper, A., Hughes, D., Edwards, R. T. & Edwards, A., 7 Mar 2024, MedRxiv, 118 p.

Research output: Working paper › Preprint

Published

The cost-effectiveness of biological therapies for Crohn's disease: markov cohot analyses incorporating UK patient-level cost data

Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 May 2008.

Research output: Contribution to conference › Paper

Published

The cost-effectiveness of biological therapies for Crohn's disease: Markov cohort analyses incorporating UK patient-level cost data

Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Mar 2008.

Research output: Contribution to conference › Paper

Published

The assessment, determinants & economics of medication compliance & persistence

Hughes, D., Hughes, D. A., Gwadry Sridhar, F. & Elliott, R., 1 Oct 2007.

Research output: Contribution to conference › Paper

Published

The all wales medicines strategy group: assessments and appraisals

Hughes, D. & Hughes, D. A., 1 Nov 2008.

Research output: Contribution to conference › Paper

Published

The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

Marson, A., Burnside, G., Appleton, R., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1375-1386

Research output: Contribution to journal › Article › peer-review

Published

The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1363-1374

Research output: Contribution to journal › Article › peer-review

Published

The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial

Jenkinson, M. D., Javadpour, M., Haylock, B. J., Young, B., Gillard, H., Vinten, J., Bulbeck, H., Das, K., Farrell, M., Looby, S., Hickey, H., Preusser, M., Mallucci, C. L., Hughes, D., Gamble, C. & Weber, D. C., 14 Nov 2015, In: Trials. 16

Research output: Contribution to journal › Article › peer-review

Published

The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

Hughes, D., Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Jan 2012, In: British Journal of Clinical Pharmacology. 73, 1, p. 66-76

Research output: Contribution to journal › Article › peer-review

Published

The Development of a Consistent Europe-Wide Approach to Investigating the Economic Impact of Myalgic Encephalomyelitis (ME/CFS): A Report from the European Network on ME/CFS (EUROMENE)

Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 7 Apr 2020, In: Healthcare. 8, 2, 88.

Research output: Contribution to journal › Article › peer-review

Published

The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol

Hughes, D., Jenkinson, M. D., Gamble, C., Hartley, J. C., Hickey, H., Hughes, D. A., Blundell, M., Griffiths, M. J., Solomon, T. & Malluci, C. L., 3 Jan 2014, In: Trials. 15, 14

Research output: Contribution to journal › Article › peer-review

Published

Taxonomy for methods of resource use measurement

DIRUM Team, 23 Jan 2015, In: Health Economics. 24, 3, p. 372-378

Research output: Contribution to journal › Letter › peer-review

Published

TEOS: A framework for constructing operational definitions of medication adherence based on Timelines – Events – Objectives – Sources

Dima, A. L., Allemann, S. S., Dunbar-Jacobs, J., Hughes, D., Vrijens, B. & Wilson, I., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2521-2533

Research output: Contribution to journal › Article › peer-review

Published

Systematic review of follow-up of cancer in primary care verses secondary care: findings for breast and lung cancer

Hughes, D., Lewis, R., Neal, R. D., France, B., Williams, N. H., Wilkinson, C., Russell, I. T., Russell, D., Hughes, D. A., Stuart, N. S. & Weller, D., 1 Mar 2007.

Research output: Contribution to conference › Paper

Published

Systematic Review: Outcomes and adverse events from randomised trials in Crohn's disease

Catt, H., Hughes, D., Kirkham, J. K. & Bodger, K., Apr 2019, In: Alimentary Pharmacology and Therapeutics. 49, 8, p. 978-996 19 p.

Research output: Contribution to journal › Article › peer-review

Published

Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation

Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. G. & Williamson, P., 1 May 2021, In: The Lancet Rheumatology. 3, 5, p. e347-e356

Research output: Contribution to journal › Article › peer-review

E-pub ahead of print

Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial

SuMMiT-D Collaborative Group , 25 Jan 2024, (E-pub ahead of print) In: Pilot and Feasibility Studies. 10, 1, 15.

Research output: Contribution to journal › Article › peer-review

Published

Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol

Farmer, A. J., Allen, J., Bartlett, K., Bower, P., Chi, Y., French, D. P., Gudgin, B., Holmes, E., Horne, R., Hughes, D., Kenning, C., Locock, L., McSharry, J., Miles, L., Newhouse, N., Rea, R., Riga, J., Tarassenko, L., Velardo, C., Williams, N., Williams, V. & Yu, L-M., 29 Dec 2019, In: BMJ Open. 9, 12, e033504.

Research output: Contribution to journal › Article › peer-review

Published

Supporting People With Type 2 Diabetes in the Effective Use of Their Medicine Through Mobile Health Technology Integrated With Clinical Care to Reduce Cardiovascular Risk: Protocol for an Effectiveness and Cost-effectiveness Randomized Controlled Trial

Farmer, A. J., Jones, L., Newhouse, N., Kenning, C., Williams, N., Chi, Y., Bartlett, K., Plumpton, C., McSharry, J., Cholerton, R., Holmes, E., Robinson, S., Allen, J., Gudgin, B., Velardo, C., Rutter, H., Horne, R., Tarassenko, L., Williams, V., Locock, L., Rea, R., Yu, L-M., Hughes, D., Bower, P. & French, D. P., 21 Feb 2022, In: JMIR Research Protocols. 11, 2, e32918.

Research output: Contribution to journal › Article › peer-review

Published

Supply-side cost-effectiveness thresholds: questions for evidence-based policy

Sampson, C., Zamora, B., Watson, S., Cairns, J., Chalkidou, K., Cubi-Molla, P., Devlin, N., García-Lorenzo, B., Hughes, D., Leech, A. & Towse, A., Sept 2022, In: Applied Health Economics and Health Policy. 20, 5, p. 651-667

Research output: Contribution to journal › Article › peer-review

Published

Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial

Marsden, J., Kelleher, M., Gilvarry, E., Mitcheson, L., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hardy, W., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Vanderwaal, R., Wareham, A., Hughes, D. & Hoare, Z., Dec 2023, In: eClinicalMedicine. 66, 23 p., 102331.

Research output: Contribution to journal › Article › peer-review

Published

Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica

Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Oct 2017, In: Health Technology Assessment. 21, 60, p. 1-180 180 p.

Research output: Contribution to journal › Article › peer-review

Published

Study protocol for a randomised controlled trial of insulin delivery by continuous subcutaneous infusion compared to multiple daily injections

Blair, J., Gregory, J., Hughes, D., Ridyard, C., Gamble, C., McKay, A., Didi, M., Thornborough, K., Bedson, E., Awoyale, L., Cwiklinski, E. & Peak, M., 16 Apr 2015, In: Trials. 16, 163.

Research output: Contribution to journal › Article › peer-review

Published

Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)

Balabanova, S., Taylor, C., Sills, G., Burnside, G., Plumpton, C., Smith, P., Appleton, R., Leach, J. P., Johnson, M., Baker, G. A., Pirmohamed, M., Hughes, D., Williamson, P., Tudor-Smith, C. & Marson, A. G., 26 Aug 2020, In: BMJ Open. 10, 8, e040635.

Research output: Contribution to journal › Article › peer-review

Published

Statistical comments are unfounded.

Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Mar 2008, In: Value in Health. 11, 2, p. 346

Research output: Contribution to journal › Article › peer-review

Published

Statistical Methods for Adjusting Estimates of Treatment Effectiveness for Patient Non-adherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Systematic Review of Methodological Papers

Alshreef, A., Latimer, N., Tappenden, P., Wong, R., Hughes, D., Fotheringham, J. & Dixon, S., Nov 2019, In: Medical Decision Making. 39, 8, p. 910-925 16 p.

Research output: Contribution to journal › Article › peer-review

Published

Societal views on NICE, cancer drugs fund and value-based pricing criteria for prioritising medicines: a cross-sectional survey of 4118 adults in Great Britain

Hughes, D., Linley, W. G. & Hughes, D. A., 1 Aug 2013, In: Health Economics. 22, 8, p. 948-964

Research output: Contribution to journal › Article › peer-review

Published

Societal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods

Bourke, S. M., Plumpton, C. & Hughes, D., 9 May 2018, In: Value in Health. 21, 5, p. 538-546

Research output: Contribution to journal › Article › peer-review

Published

Societal perspective on access to publicly subsidised medicines: A cross sectional survey of 3080 adults in Australia

Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 1 Mar 2017, In: PLoS ONE.

Research output: Contribution to journal › Article › peer-review

Published

Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT

Mallucci, C. L., Jenkinson, M., Conroy, E. J., Hartley, J. C., Brown, M., Moitt, T., Dalton, J., Kearns, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 2 Apr 2020, In: Health Technology Assessment. 24, 17, 114 p.

Research output: Contribution to journal › Article › peer-review

Published

Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project

Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 17-27 11 p.

Research output: Contribution to journal › Article › peer-review

Published

Seizure First Aid Training For people with Epilepsy (SAFE) frequently attending emergency departments and their significant others: results of a UK multi-centre randomised controlled pilot trial

Noble, A. J., Snape, D., Nevitt, S., Holmes, E., Morgan, M., Smith, C. T., Hughes, D., Buchanan, M., McVicar, J., MacCallum, E., Goodacre, S., Rinsdale, L. & Marson, A. G., 16 Apr 2020, In: BMJ Open. 10, 4, e035516.

Research output: Contribution to journal › Article › peer-review

Published

Screening log data can be used to inform protocol modifications, increasing patient recrutiment to a challanging clinical trial

Blair, J., Awoyale, L., Thornborough, K., Peak, M., Didi, M., Bedson, E., Hughes, D., Ridyard, C., Tat, T. & Gregory, J., Nov 2013.

Research output: Contribution to conference › Paper › peer-review

Published

Review of the use of resource use instruments based on patient recall in relation to other methods of resource use estimation

Ridyard, C. & Hughes, D., Nov 2013.

Research output: Contribution to conference › Paper › peer-review

Published

Review of the Use of Resource Use Instruments Based on Patient Recall in Relation to Other Methods of Cost Estimation

Ridyard, C. & Hughes, D., Nov 2013.

Research output: Contribution to conference › Paper › peer-review

Published

Review of resource-use measures in UK economic evaluations

Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (eds.). University of Kent, Canterbury, p. 22-31 10 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Published

Resource-Use Measurement Based on Patient Recall: Issues and Challenges for Economic Evaluation

Thorn, J. C., Coast, J., Cohen, D., Hollingworth, W., Knapp, M., Noble, S. M., Ridyard, C. H., Wordsworth, S. & Hughes, D., 1 Jun 2013, In: Applied Health Economics and Health Policy. 11, 3, p. 155-161

Research output: Contribution to journal › Article › peer-review

Published

Renal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment

Hagemi, A., Plumpton, C. & Hughes, D., 2 Oct 2017, In: BMC Nephrology. 18, 305.

Research output: Contribution to journal › Article › peer-review

Published

Reimbursement Decisions of the All Wales Medicines Strategy Group

Hughes, D., Linley, W. G. & Hughes, D. A., 1 Sept 2012, In: PharmoEconomics. 30, 9, p. 779-794

Research output: Contribution to journal › Article › peer-review

Published

Rationing of drugs for rare diseases.

Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 4, p. 315-316

Research output: Contribution to journal › Article › peer-review

Published

Rationing of drugs for rare diseases

Hughes, D. & Hughes, D. A., 1 Apr 2006.

Research output: Contribution to conference › Paper

Published

Rare disease prevention and treatment: The need for a level playing field

Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247

Research output: Contribution to journal › Article › peer-review

Published

Rare Disease Terminology and Definitions—A Systematic Global Review: Report of the ISPOR Rare Disease Special Interest Group

Hughes, D., Richter, T., Nestler-Parr, S., Babela, R., Khan, Z. M., Tesoro, T., Molsen, E. & Hughes, D. A., 18 Aug 2015, In: Value in Health. 18, 6, p. 906-914

Research output: Contribution to journal › Article › peer-review

Published

RES00038. Wales COVID-19 Evidence Centre. A rapid evidence summary of the cost impact of Long COVID on employment and caring responsibilities

Spencer, L., Hendry, A., Davies, J., Pisavadia, K., Hughes, D. & Edwards, R. T., May 2022, Welsh Government. 18 p.

Research output: Book/Report › Other report

Published

RES00019. Wales COVID-19 Evidence Centre. A rapid evidence summary indicating the evidence of the inverse care law in social care in Wales and has this been exacerbated by the COVID-19 pandemic?

Spencer, L., Hendry, A., Makanjuola, A., Hughes, D., Wilkinson, C., Pisavadia, K., Davies, J., Fitzsimmons, D. & Edwards, R. T., Feb 2022, Welsh Government. 33 p.

Research output: Book/Report › Other report

Published

Quantitative risk-benefit analysis

Hughes, D. & Hughes, D. A., 1 May 2007.

Research output: Contribution to conference › Paper

Published

Quantitative evidence synthesis methods for the assessment of the effectiveness of treatment sequences for clinical and economic decision-making: a review and taxonomy of simplifying assumptions

Lewis, R., Hughes, D., Sutton, AJ. & Wilkinson, C., Jan 2021, In: PharmacoEconomics. 39, 1, p. 25-61 37 p.

Research output: Contribution to journal › Article › peer-review

Published

Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

Ridyard, C., Blair, J. & Hughes, D., Nov 2017, In: Value in Health. 20, 9, p. A481 - A482

Research output: Contribution to journal › Article › peer-review

Published

Public meetings of the NICE appraisals committee

Hughes, D. & Hughes, D. A., 1 Dec 2007.

Research output: Contribution to conference › Paper

Published

Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness: Evidence Tables.

Hughes, D., Linck, P. G., Windle, G., Linck, P., Morgan, R., Hughes, D. A., Burholt, V., Reeves, C., Yeo, S. T., Woods, R. T., Edwards, R. T. & Russell, I. T., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T., Morgan, R., Woods, R. T., Burholt, V., Edwards, R. T., Reeves, C. & Yeo, S. T., 1 Jan 2008, 2008 ed. Unknown.

Research output: Book/Report › Commissioned report

Published

Public health interventions to promote mental well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

Hughes, D., Windle, G., Hughes, D. A., Linck, P., Morgan, R., Burholt, V., Edwards, R. T., Reeves, C., Yeo, S. T., Woods, R. T. & Russell, I. T., 1 Jan 2007, 2007 ed. Unknown.

Research output: Book/Report › Commissioned report

Published