Dr Ramsay Mcfarlane

Senior Lecturer in Biomedical Sciences (Medical & Molecular Genetics)

Contact info

Location: Brambell, Room 405

Phone: 2360

Email: r.macfarlane@bangor.ac.uk

Position: Senior Lecturer / Research Group Leader / Deputy Head of School – Research

  1. Published

    The immortal strand hypothesis: still non-randomly segregating opinion.

    Wakeman, J., Hmadcha, A., Soria, B. & Mcfarlane, R., 23 Mar 2012, In: Biomolecular Concepts. 3, 3, p. 203-211

    Research output: Contribution to journalArticlepeer-review

  2. Published

    Comparative proteomic analysis reveals differential expression of Hsp25 following the directed differentiation of mouse embryonic stem cells.

    Wakeman, J., Mcfarlane, R. J., Battersby, A., Jones, R. D., Lilley, K. S., McFarlane, R. J., Braig, H. R., Allen, N. D. & Wakeman, J. A., 1 Feb 2007, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1773, 2, p. 147-156

    Research output: Contribution to journalArticlepeer-review

  3. Published

    5-azacytidine treatment of the fission yeast leads to cytotxicity and cell cycle arrest.

    Taylor, E. M., Mcfarlane, R. & Price, C., 1996, In: Molecular Genetics and Genomics. 253, 1-2, p. 128-137

    Research output: Contribution to journalArticlepeer-review

  4. Published

    Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes.

    Stuart, N. S., Wakeman, J., Mcfarlane, R. J., Feichtinger, J., Aldeailej, I., Anderson, R., Almutairi, M., Almatrafi, A., Alsiwiehri, N., Griffiths, K., Stuart, N., Wakeman, J. A., Larcombe, L. & McFarlane, R. J., 13 Aug 2012, In: Oncotarget. 3, 8, p. 843-853

    Research output: Contribution to journalArticlepeer-review

  5. Published

    A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets

    Sammut, S. J., Feichtinger, J., Stuart, N. S., Wakeman, J., Larcombe, L. & Mcfarlane, R. J., 6 May 2014, In: Oncoscience. 1, 5, p. 349-359

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Cancer/Testis Antigens and Colorectal Cancer

    Sammut, S. J., Wakeman, J., Mcfarlane, R. J., Sammut, J., Wakeman, J. A., Stuart, N. & McFarlane, R. J., 13 Jun 2013, In: Journal of Genetic Syndromes and Gene Therapy. 4, 5, p. 149

    Research output: Contribution to journalArticlepeer-review

  7. Published

    Brachyury: Strategies for Drugging an Intractable Cancer Therapeutic Target

    Robinson, H., McFarlane, R. J. & Wakeman, J. A., Apr 2020, In: Trends in cancer. 6, 4, p. 271-273 3 p.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    The Meiotic Recombination Hotspots of Schizosaccharomyces pombe

    Pryce, D. & Mcfarlane, R. J., 1 Jan 2009, In: Meiosis. 5, p. 1-13

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Recombination at DNA replication fork barriers is not universal and is differentially regulated by Swi1

    Pryce, D. W., Ramayah, S., Jaendling, A. & Mcfarlane, R., 24 Mar 2009, In: Proceedings of the National Academy of Sciences of the USA. 106, 12, p. 4770-4775

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis

    Planells Palop, V., Hazazi, A., Feichtinger, J., Jezkova, J., Thallinger, G. G., Alsiwiehri, N., Almutairi, M., Parry, L., Wakeman, J. & Mcfarlane, R., 26 Apr 2017, In: Molecular Cancer. 16, 1, p. 1-18 84.

    Research output: Contribution to journalArticlepeer-review

  11. Published
  12. Published

    Meiosis-like functions in oncogenesis: a new view of cancer.

    Mcfarlane, R. & Wakeman, J., Nov 2017, In: Cancer Research. 77, 21, p. 5712-5716

    Research output: Contribution to journalArticlepeer-review

  13. Published

    Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function.

    Mcfarlane, R., Carr, A. M. & Price, C., 1 Jul 1997, In: Molecular Genetics and Genomics. 255, 3, p. 332-340

    Research output: Contribution to journalArticlepeer-review

  14. Published

    Meiotic gene activation in somatic and germ cell tumours

    Mcfarlane, R. & Feichtinger, J., Jul 2019, In: Andrology. 7, 4, p. 415-427 13 p.

    Research output: Contribution to journalArticlepeer-review

  15. Published

    The many facets of the Tim-Tipin protein families' roles in chromosome biology.

    Mcfarlane, R. J., McFarlane, R. J., Mian, S. & Dalgaard, J. Z., 15 Feb 2010, In: Cell Cycle. 9, 4, p. 700-705

    Research output: Contribution to journalArticlepeer-review

  16. Published

    The unique centromeric chromatin structure of Schizosaccharomyces pombe is maintained during meiosis.

    Mcfarlane, R. J., Smirnova, J. B. & McFarlane, R. J., 31 May 2002, In: Journal of Biological Chemistry. 277, 22, p. 19817-19822

    Research output: Contribution to journalArticlepeer-review

  17. Published

    A role for recombination in centromere function.

    Mcfarlane, R. J., McFarlane, R. J. & Humphrey, T. C., 1 May 2010, In: Trends in Genetics. 26, 5, p. 209-213

    Research output: Contribution to journalArticlepeer-review

  18. Published

    Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX.

    Mcfarlane, R. J., Jaendling, A., Ramayah, S., Pryce, D. W. & McFarlane, R. J., 1 Feb 2008, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1783, 2, p. 203-213

    Research output: Contribution to journalArticlepeer-review

  19. Published

    SUMOylation is required for normal development of linear elements and wild-type meiotic recombination in Schizosaccharomyces pombe.

    Mcfarlane, R. J., Spirek, M., Estreicher, A., Csaszar, E., Wells, J., McFarlane, R. J., Watts, F. Z. & Loidl, J., 1 Feb 2010, In: Chromosoma. 119, 1, p. 59-72

    Research output: Contribution to journalArticlepeer-review

  20. Published

    Germline/meiotic genes in cancer: new dimensions

    Mcfarlane, R. J., McFarlane, R. J., Feichtinger, J. & Larcombe, L., 19 Mar 2015, In: Cell Cycle. 14, 6, p. 791-792

    Research output: Contribution to journalArticlepeer-review

  21. Published

    Biological roles of translin and translin-associated factor-X: RNA metabolism comes to the fore.

    Mcfarlane, R. J., Jaendling, A. & McFarlane, R. J., 15 Jul 2010, In: Biochemical Journal. 429, 2, p. 225-234

    Research output: Contribution to journalArticlepeer-review

  22. Published

    Homologous chromosome pairing in Schizosaccharomyces pombe

    Mcfarlane, R. J., Wells, J. L., Pryce, D. W. & McFarlane, R. J., 15 Oct 2006, In: Yeast. 23, 13, p. 977-989

    Research output: Contribution to journalArticlepeer-review

  23. Published

    tRNA genes in eukaryotic genome organization and reorganization.

    Mcfarlane, R. J., McFarlane, R. J. & Whitehall, S. K., 1 Oct 2009, In: Cell Cycle. 8, 19, p. 3102-3106

    Research output: Contribution to journalArticlepeer-review

  24. Published

    Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathway

    Mcfarlane, R. J., Gollins, S. W., Wakeman, J., Jezkova, J., Williams, J. S., Jones-Hutchins, F., Sammut, S. J., Gollins, S., Cree, I., Coupland, S., McFarlane, R. J. & Wakeman, J. A., 21 May 2014, In: Oncotarget. 5, 11, p. 3813-3822

    Research output: Contribution to journalArticlepeer-review

  25. Published

    Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe.

    Mcfarlane, R. J., Pryce, D. W., Lorenz, A., Smirnova, J. B., Loidl, J. & McFarlane, R. J., 1 May 2005, In: Genetics. 170, 1, p. 95-106

    Research output: Contribution to journalArticlepeer-review

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