Dr Ramsay Mcfarlane
Senior Lecturer in Biomedical Sciences (Medical & Molecular Genetics)
Affiliations
Contact info
Location: Brambell, Room 405
Phone: 2360
Email: r.macfarlane@bangor.ac.uk
Position: Senior Lecturer / Research Group Leader / Deputy Head of School – Research
- Published
The immortal strand hypothesis: still non-randomly segregating opinion.
Wakeman, J., Hmadcha, A., Soria, B. & Mcfarlane, R., 23 Mar 2012, In: Biomolecular Concepts. 3, 3, p. 203-211Research output: Contribution to journal › Article › peer-review
- Published
Comparative proteomic analysis reveals differential expression of Hsp25 following the directed differentiation of mouse embryonic stem cells.
Wakeman, J., Mcfarlane, R. J., Battersby, A., Jones, R. D., Lilley, K. S., McFarlane, R. J., Braig, H. R., Allen, N. D. & Wakeman, J. A., 1 Feb 2007, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1773, 2, p. 147-156Research output: Contribution to journal › Article › peer-review
- Published
5-azacytidine treatment of the fission yeast leads to cytotxicity and cell cycle arrest.
Taylor, E. M., Mcfarlane, R. & Price, C., 1996, In: Molecular Genetics and Genomics. 253, 1-2, p. 128-137Research output: Contribution to journal › Article › peer-review
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Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes.
Stuart, N. S., Wakeman, J., Mcfarlane, R. J., Feichtinger, J., Aldeailej, I., Anderson, R., Almutairi, M., Almatrafi, A., Alsiwiehri, N., Griffiths, K., Stuart, N., Wakeman, J. A., Larcombe, L. & McFarlane, R. J., 13 Aug 2012, In: Oncotarget. 3, 8, p. 843-853Research output: Contribution to journal › Article › peer-review
- Published
A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets
Sammut, S. J., Feichtinger, J., Stuart, N. S., Wakeman, J., Larcombe, L. & Mcfarlane, R. J., 6 May 2014, In: Oncoscience. 1, 5, p. 349-359Research output: Contribution to journal › Article › peer-review
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Cancer/Testis Antigens and Colorectal Cancer
Sammut, S. J., Wakeman, J., Mcfarlane, R. J., Sammut, J., Wakeman, J. A., Stuart, N. & McFarlane, R. J., 13 Jun 2013, In: Journal of Genetic Syndromes and Gene Therapy. 4, 5, p. 149Research output: Contribution to journal › Article › peer-review
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Brachyury: Strategies for Drugging an Intractable Cancer Therapeutic Target
Robinson, H., McFarlane, R. J. & Wakeman, J. A., Apr 2020, In: Trends in cancer. 6, 4, p. 271-273 3 p.Research output: Contribution to journal › Article › peer-review
- Published
The Meiotic Recombination Hotspots of Schizosaccharomyces pombe
Pryce, D. & Mcfarlane, R. J., 1 Jan 2009, In: Meiosis. 5, p. 1-13Research output: Contribution to journal › Article › peer-review
- Published
Recombination at DNA replication fork barriers is not universal and is differentially regulated by Swi1
Pryce, D. W., Ramayah, S., Jaendling, A. & Mcfarlane, R., 24 Mar 2009, In: Proceedings of the National Academy of Sciences of the USA. 106, 12, p. 4770-4775Research output: Contribution to journal › Article › peer-review
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Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis
Planells Palop, V., Hazazi, A., Feichtinger, J., Jezkova, J., Thallinger, G. G., Alsiwiehri, N., Almutairi, M., Parry, L., Wakeman, J. & Mcfarlane, R., 26 Apr 2017, In: Molecular Cancer. 16, 1, p. 1-18 84.Research output: Contribution to journal › Article › peer-review
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Molecular mechanisms of intramolecular recombination-dependent recircularization of linearized plasmid DNA in Escherichia coli: requirements for ruvA, ruvB, recG, recF and recR gene products.
Mcfarlane, R. & Saunders, J. R., 1996, In: Gene. 177, 1-2, p. 209-216Research output: Contribution to journal › Article › peer-review
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Meiosis-like functions in oncogenesis: a new view of cancer.
Mcfarlane, R. & Wakeman, J., Nov 2017, In: Cancer Research. 77, 21, p. 5712-5716Research output: Contribution to journal › Article › peer-review
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Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function.
Mcfarlane, R., Carr, A. M. & Price, C., 1 Jul 1997, In: Molecular Genetics and Genomics. 255, 3, p. 332-340Research output: Contribution to journal › Article › peer-review
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Meiotic gene activation in somatic and germ cell tumours
Mcfarlane, R. & Feichtinger, J., Jul 2019, In: Andrology. 7, 4, p. 415-427 13 p.Research output: Contribution to journal › Article › peer-review
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The many facets of the Tim-Tipin protein families' roles in chromosome biology.
Mcfarlane, R. J., McFarlane, R. J., Mian, S. & Dalgaard, J. Z., 15 Feb 2010, In: Cell Cycle. 9, 4, p. 700-705Research output: Contribution to journal › Article › peer-review
- Published
The unique centromeric chromatin structure of Schizosaccharomyces pombe is maintained during meiosis.
Mcfarlane, R. J., Smirnova, J. B. & McFarlane, R. J., 31 May 2002, In: Journal of Biological Chemistry. 277, 22, p. 19817-19822Research output: Contribution to journal › Article › peer-review
- Published
A role for recombination in centromere function.
Mcfarlane, R. J., McFarlane, R. J. & Humphrey, T. C., 1 May 2010, In: Trends in Genetics. 26, 5, p. 209-213Research output: Contribution to journal › Article › peer-review
- Published
Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX.
Mcfarlane, R. J., Jaendling, A., Ramayah, S., Pryce, D. W. & McFarlane, R. J., 1 Feb 2008, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1783, 2, p. 203-213Research output: Contribution to journal › Article › peer-review
- Published
SUMOylation is required for normal development of linear elements and wild-type meiotic recombination in Schizosaccharomyces pombe.
Mcfarlane, R. J., Spirek, M., Estreicher, A., Csaszar, E., Wells, J., McFarlane, R. J., Watts, F. Z. & Loidl, J., 1 Feb 2010, In: Chromosoma. 119, 1, p. 59-72Research output: Contribution to journal › Article › peer-review
- Published
Germline/meiotic genes in cancer: new dimensions
Mcfarlane, R. J., McFarlane, R. J., Feichtinger, J. & Larcombe, L., 19 Mar 2015, In: Cell Cycle. 14, 6, p. 791-792Research output: Contribution to journal › Article › peer-review
- Published
Biological roles of translin and translin-associated factor-X: RNA metabolism comes to the fore.
Mcfarlane, R. J., Jaendling, A. & McFarlane, R. J., 15 Jul 2010, In: Biochemical Journal. 429, 2, p. 225-234Research output: Contribution to journal › Article › peer-review
- Published
Homologous chromosome pairing in Schizosaccharomyces pombe
Mcfarlane, R. J., Wells, J. L., Pryce, D. W. & McFarlane, R. J., 15 Oct 2006, In: Yeast. 23, 13, p. 977-989Research output: Contribution to journal › Article › peer-review
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tRNA genes in eukaryotic genome organization and reorganization.
Mcfarlane, R. J., McFarlane, R. J. & Whitehall, S. K., 1 Oct 2009, In: Cell Cycle. 8, 19, p. 3102-3106Research output: Contribution to journal › Article › peer-review
- Published
Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathway
Mcfarlane, R. J., Gollins, S. W., Wakeman, J., Jezkova, J., Williams, J. S., Jones-Hutchins, F., Sammut, S. J., Gollins, S., Cree, I., Coupland, S., McFarlane, R. J. & Wakeman, J. A., 21 May 2014, In: Oncotarget. 5, 11, p. 3813-3822Research output: Contribution to journal › Article › peer-review
- Published
Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe.
Mcfarlane, R. J., Pryce, D. W., Lorenz, A., Smirnova, J. B., Loidl, J. & McFarlane, R. J., 1 May 2005, In: Genetics. 170, 1, p. 95-106Research output: Contribution to journal › Article › peer-review