1. Published

   The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies.

   Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

   Research output: Book/Report › Commissioned report

2. Published

   Drugs for exceptionally rare diseases: do they deserve special status for funding?

   Hughes, D., Tunnage, B. & Yeo, S. T., 1 Nov 2005, In: QJM - An International Journal of Medicine. 98, 11, p. 829-836

   Research output: Contribution to journal › Article › peer-review

3. Published

   Adverse drug reactions in economic evaluations

   Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A109

   Research output: Contribution to journal › Article › peer-review

4. Published

   Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity

   Hughes, D., Hughes, D. A., Vilar, F. J., Ward, C. C., Alfirevic, A., Park, B. K. & Pirmohamed, M., 1 Jun 2004, In: Pharmacogenetics. 14, 6, p. 335-342

   Research output: Contribution to journal › Article › peer-review

5. Published

   Methodological issues in the literature on costs of non-compliance in chronic diseases

   Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008.

   Research output: Contribution to conference › Paper

6. Published

   Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses

   Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., N. V., 31 Oct 2011, In: British Medical Journal. 343, p. 1-14

   Research output: Contribution to journal › Article › peer-review

7. Published

   Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

   Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Nov 2003, In: Value in Health. 6, 6, p. 749

   Research output: Contribution to journal › Article › peer-review

8. Published

   Pharmacogenetic tests: the need for a level playing field

   Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4

   Research output: Contribution to journal › Article › peer-review

9. Published

   Drug compliance and pharmaceconomics

   Hughes, D. & Hughes, D. A., 1 Dec 2003.

   Research output: Contribution to conference › Paper

10. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Tenofovir disoproxil fumarate (Viread) for the treatment of hepatitis B.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

11. Published

    Economic evaluation during early (phase II) trials

    Hughes, D. & Hughes, D. A., 1 Nov 2002.

    Research output: Contribution to conference › Paper

12. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-experienced patients.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

13. Published

    A parenting programme for children at risk of developing conduct disorder: A cost-effectiveness analysis

    Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 1 May 2007.

    Research output: Contribution to conference › Paper

14. Published

    Economic evaluations during early (Phase II) drug development: A role for clinical trial simulations.

    Hughes, D., Hughes, D. A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 11, p. 1069-1077

    Research output: Contribution to journal › Article › peer-review

15. Published

    A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)

    Hughes, D., Ramanan, A., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., Hickey, H., Hughes, D. A., Jones, A., Woo, P., Edelsten, C., Beresford, M. W. & The SYCAMORE Trail Management Group, N. V., 9 Jan 2014, In: Trials. 15, 14

    Research output: Contribution to journal › Article › peer-review

16. Published

    Abolition of prescription copayments in Wales: an observational study on dispensing rates.

    Hughes, D., Cohen, D., Alam, M. F., Dunstan, F. D., Myles, S., Hughes, D. A. & Routledge, P. A., 1 Aug 2010, In: Value in Health. 13, 5, p. 675-680

    Research output: Contribution to journal › Article › peer-review

17. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conference › Paper

18. Published

    Effects of the abolition of prescription charges in Wales: A preliminary analysis

    Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

    Research output: Contribution to conference › Paper

19. Published

    Impact of the abolition of the prescription charge in Wales

    Hughes, D. & Hughes, D. A., 1 Nov 2008.

    Research output: Contribution to conference › Paper

20. Published

    The economics of evergreening.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conference › Paper

21. Published

    Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations.

    Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Nov 2007, In: Value in Health. 10, 6, p. 498-509

    Research output: Contribution to journal › Article › peer-review

22. Published

    All Wales Medicines Strategy Group Final Assessment Report – Agalsidase alfa (Replagal)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

23. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Chronic, accelerated or blast phase CML.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

24. Published

    A prototype agent-based model of antimalarial drug compliance

    Hughes, D., McKean, J., Rahlf, S., Shorter, H., Barnish, G., Paton, R., McBurney, P., Hughes, D. A. & Hastings, I., 1 Aug 2007.

    Research output: Contribution to conference › Paper

25. Published

    Back to basics: what is the relationship between dose and duration of drug action?

    Hughes, D. & Hughes, D. A., 1 May 2006.

    Research output: Contribution to conference › Paper

26. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Parathyroid hormone (Preotact)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

27. Published

    Mechanism-Based Approach to the Economic Evaluation of Pharmaceuticals: Pharmacokinetic/Pharmacodynamic/Pharmacoeconomic Analysis of Rituximab for Follicular Lymphoma.

    Hughes, D., Pink, J., Lane, S. & Hughes, D. A., 19 Mar 2012, In: Pharmacoeconomics.

    Research output: Contribution to journal › Article › peer-review

28. Published

    What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?

    Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.

    Research output: Contribution to conference › Paper

29. Published

    Is exercise effective in promoting mental well-being in older age? A systematic review.

    Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Aug 2010, In: Aging and Mental Health. 14, 6, p. 652-669

    Research output: Contribution to journal › Article › peer-review

30. Published

    Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

    Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417

    Research output: Contribution to journal › Article › peer-review

31. Published

    The problem of orphan drugs

    Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Nov 2010, In: British Medical Journal. 341, p. 335-341

    Research output: Contribution to journal › Article › peer-review

32. Published

    Temporal variations in dissolved organic carbon concentrations in upland and lowland lakes in North Wales

    Hughes, D. D., Holliman, P. J., Jones, T. & Freeman, C., 1 Jun 2013, In: Water and Environment Journal. 27, 2, p. 275-283

    Research output: Contribution to journal › Article › peer-review

33. Published

    Assessment of potential climate change impacts on peatland dissolved organic carbon release and drinking water treatment from laboratory experiments

    Hughes, D. D., Tang, R., Clark, J. M., Bond, T., Graham, N., Hughes, D. & Freeman, C., 1 Feb 2013, In: Environmental Pollution. 173, p. 270-277

    Research output: Contribution to journal › Article › peer-review

34. Published

    The effects of megafaunal burrows on radiotracer profiles and organic composition in deep sea sediments:preliminary results from two sites in the bathyal north-east Atlantic.

    Hughes, D. J., Brown, L., Cook, G. T., Cowie, G., Gage, J. D., Good, E., Kennedy, H. A., MacKenzie, A. B., Papadimitriou, S., Shimmield, G. B., Thomson, J. & Williams, M., 1 Jan 2005, In: Deep Sea Research Part I: Oceanographic Research Papers. 52, 1, p. 1-13

    Research output: Contribution to journal › Article › peer-review

35. Published

    InK-Compact: In-Kernel Stream Compaction and Its Application to Multi-Kernel Data Visualization on General-Purpose GPUs

    Hughes, D. M., Lim, I. S., Jones, M., Knoll, A. & Spencer, B., 1 Sept 2013, In: Computer Graphics Forum. 32, 6, p. 178-188

    Research output: Contribution to journal › Article › peer-review

36. Published

    A case-study of inconsistent surface reconstruction in recent literature resulting from Octree rotation-variance

    Hughes, D. M. & Lim, I. S., 1 Jan 2007, p. 195-200.

    Research output: Contribution to conference › Paper

37. Published

    Context-preserving rendering of medical segmentation data.

    Hughes, D. M. & Lim, I. S., 1 Jan 2007, p. 5521-5524.

    Research output: Contribution to conference › Paper

38. Published

    Kd-Jump: a Path-Preserving Stackless Traversal for Faster Isosurface Raytracing on GPUs.

    Hughes, D. M. & Lim, I. S., 1 Nov 2009, In: IEEE Transactions on visualization and computer graphics. 15, 6, p. 1555-1562

    Research output: Contribution to journal › Article › peer-review

39. Published

    (Lynette writing about) Nesta: Recollection, Reclamation and Reconstruction in Lynette Roberts's Lost Novel

    Hughes, D., 20 Dec 2018, In: International Journal of Welsh Writing in English. 5, 2

    Research output: Contribution to journal › Article › peer-review

40. Published

    Welsh Literary Modernism, Lynette Roberts and David Jones: "unearthing a huge and very important culture"

    Hughes, D., 2 Apr 2019, Locating Lynette Roberts: Always observant and slightly obscure. McAvoy, S. (ed.). University of Wales Press, Cardiff, (Writing Wales in English).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

41. Published

    David Jones on Religion, Politics, and Culture: Unpublished Prose

    Hughes, D., 1 Oct 2019, In: Modern Language Review. 114, 4, p. 886-887

    Research output: Contribution to journal › Book/Film/Article review

42. Published

    Lynette Roberts and the Chronology of Welsh Literary Modernism

    Hughes, D., 2014

    Research output: Other contribution

43. Published

    Rapid, Semi-Automated Fractionation of Freshwater Dissolved Organic Carbon Using DAX 8 (XAD 8) and XAD 4 Resins in Tandem

    Hughes, D., Holliman, P., Jones, T., Jones, T., Butler, A. J. & Freeman, C., 22 Nov 2016, In: Natural Science. 8, 11, p. 487-498

    Research output: Contribution to journal › Article › peer-review

44. Published

    Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.

    Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25

    Research output: Contribution to journal › Letter › peer-review

45. Published

    Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam

    Hughes, D., Nov 2020, In: British Journal of Pharmacology. 177, 21, p. 4975-4989 15 p.

    Research output: Contribution to journal › Article › peer-review

46. Published

    Management of Patients Symptomatically Unresponsive to Levothyroxine: Natural Desiccated Thyroid Extract or the Combination of Levothyroxine and Liothyronine? A Research Priority

    Hughes, D., Livingston, M. & Heald, A., Sept 2020, In: Experimental and Clinical Endocrinology & Diabetes . 128, 9, p. 596-598

    Research output: Contribution to journal › Letter › peer-review

47. Published

    Liothyronine for hypothyroidism: A candidate for disinvestment or in need of further research? A value of information analysis

    Hughes, D., Skiadas, K., Fitzsimmons, D., Anderson, P. & Heald, A., 3 Dec 2021, In: BMJ Open. 11, 12, e051702.

    Research output: Contribution to journal › Article › peer-review

48. Published

    Medication adherence – key considerations for clinical pharmacologists

    Hughes, D., Apr 2020, In: British Journal of Clinical Pharmacology. 86, 4, p. 628-629 2 p.

    Research output: Contribution to journal › Editorial › peer-review

49. E-pub ahead of print

    We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment

    Hughes, D., 27 Sept 2023, (E-pub ahead of print) In: Health Economics, Policy and Law.

    Research output: Contribution to journal › Article › peer-review

50. Published

    Medicines Shortages in the United Kingdom

    Hughes, D., Oct 2019, In: Clinical Pharmacology and Therapeutics. 106, 4, p. 712

    Research output: Contribution to journal › Letter › peer-review