Professor Dyfrig Hughes
Athro mewn Ffarmacoeconomeg / Cyfarwyddwr Ymchwil
![](https://research.bangor.ac.uk/portal/files/28327363/Dyfrig_Hughes.jpg)
- 2019
- Published
Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE)
de Geest, S., Zullig, L. L., Dunbar-Jacob, J., Hughes, D., Wilson, I. & Vrijens, B., 1 Apr 2019, In: European Journal of Cardiovascular Nursing. 18, 4, p. 258-259 2 p.Research output: Contribution to journal › Editorial › peer-review
- Published
Systematic Review: Outcomes and adverse events from randomised trials in Crohn's disease
Catt, H., Hughes, D., Kirkham, J. K. & Bodger, K., Apr 2019, In: Alimentary Pharmacology and Therapeutics. 49, 8, p. 978-996 19 p.Research output: Contribution to journal › Article › peer-review
- Published
Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis
Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. 415-424Research output: Contribution to journal › Article › peer-review
- Published
Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.
Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25Research output: Contribution to journal › Letter › peer-review
- Published
Patient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs
Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Mar 2019, In: Clinical Pharmacology and Therapeutics. 105, 3, p. 672-683 12 p.Research output: Contribution to journal › Article › peer-review
- Published
CARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial
Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Feb 2019, In: Trials. 20, 1, 16 p., 105.Research output: Contribution to journal › Article › peer-review
- Published
Community views on factors affecting medicines resource allocation: Cross-sectional survey of 3080 adults in Australia
Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 2019, In: Australian Health Review . 43, 3, p. 254-260Research output: Contribution to journal › Article › peer-review
- 2018
- Published
Cost-Effectiveness Analysis of the Use of Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing in Primary Care
Holmes, E., Harris, S. D., Hughes, A., Craine, N. & Hughes, D., 7 Dec 2018, In: Antibiotics. 7, 4, 19 p., 106.Research output: Contribution to journal › Article › peer-review
- Published
Impact of non-adherence and flare resolution on the cost effectiveness of treatments for gout: Application of a linked pharmacometric/pharmacoeconomic model
Hill-McManus, D., Marshall, S., Soto, E., Lane, S. & Hughes, D., Dec 2018, In: Value in Health. 21, 12, p. 1373-1381Research output: Contribution to journal › Article › peer-review
- Published
Mapping ALSFRS-R and ALSUI to EQ-5D in patients with motor neurone disease
Moore, A., Young, C. A. & Hughes, D., Nov 2018, In: Value in Health. 21, 11, p. 1322-1329Research output: Contribution to journal › Article › peer-review
- Published
Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care
Swift, B., Jain, L., White, C., Chandrasekaran, V., Bhandari, A., Hughes, D. & Jadhav, P., Sept 2018, In: Clinical and Translational Science. 11, 5, p. 450-460 11 p.Research output: Contribution to journal › Article › peer-review
- Published
Letter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma
Jenkinson, M., Weber, D., Haylock, B., Sherratt, F., Young, B., Weller, M., Bulbeck, H., Culeddu, G., Hughes, D., Brain, A., Das, K., Preusser, M., Francis, P. & Gamble, C., 17 Aug 2018, In: Journal of Neurology, Neurosurgery and Psychiatry.Research output: Contribution to journal › Letter › peer-review
- Published
Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT
Blair, J., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. & Gamble, C., Aug 2018, In: Health Technology Assessment. 22, 42, p. 1-112 112 p.Research output: Contribution to journal › Article › peer-review
- Published
Lessons learnt from a discontinued randomised controlled trial: Adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC)
Williams, N., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Jul 2018, In: Trials. 19, 408.Research output: Contribution to journal › Article › peer-review
- Published
ESPACOMP Medication Adherence Reporting Guideline (EMERGE)
De Geest, S., Zullig, L. L., Dunbar-Jacob, J., Helmy, R., Hughes, D., Wilson, I. & Vrijens, B., 3 Jul 2018, In: Annals of Internal Medicine. 169, 1, p. 30-35Research output: Contribution to journal › Article › peer-review
- Published
Do guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review
Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Jul 2018, In: Thorax. 73, 7, p. 670-673Research output: Contribution to journal › Letter › peer-review
- Published
Core items for a standardized resource-use measure (ISRUM): expert Delphi consensus survey
Thom, J., Brookes, S. T., Ridyard, C., Riley, R., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., Jun 2018, In: Value in Health. 21, 6, p. 640-649Research output: Contribution to journal › Article › peer-review
- Published
Societal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods
Bourke, S. M., Plumpton, C. & Hughes, D., 9 May 2018, In: Value in Health. 21, 5, p. 538-546Research output: Contribution to journal › Article › peer-review
- Published
Economics of pharmacogenetic guided treatments: Underwhelming or overstated?
Hughes, D., May 2018, In: Clinical Pharmacology and Therapeutics. 103, 5, p. 749-751Research output: Contribution to journal › Article › peer-review
- Published
New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes
Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., May 2018, In: Pharmacoeconomics. 36, 5, p. 613-624 12 p.Research output: Contribution to journal › Article › peer-review
- Published
Rare disease prevention and treatment: The need for a level playing field
Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247Research output: Contribution to journal › Article › peer-review
- Published
Impact of non-adherence on the safety and efficacy of uric acid lowering therapies in the treatment of gout
Hill McManus, D., Soto, E., Marshall, S., Lane, S. & Hughes, D., Jan 2018, In: British Journal of Clinical Pharmacology. 84, 1, p. 142-152Research output: Contribution to journal › Article › peer-review
- Published
Impact on the phased abolition of co-payments on the utilisation of selected prescription medicines in Wales
Alam, M. F., Cohen, D., Dunstan, F., Hughes, D. & Routledge, P. A., Jan 2018, In: Health Economics. 27, 1, p. 236-243Research output: Contribution to journal › Article › peer-review
- 2017
- Published
Decision analytic modelling methods for the assessing the effectiveness of treatment sequences for clinical and economic decision making: a methodological review
Lewis, R., Hughes, D. & Wilkinson, C., 30 Nov 2017, In: Value in Health. 20, 9, p. A748 1 p.Research output: Contribution to journal › Article › peer-review
- Published
Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., Nov 2017, In: Value in Health. 20, 9, p. A481 - A482Research output: Contribution to journal › Article › peer-review
- Published
Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica
Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Oct 2017, In: Health Technology Assessment. 21, 60, p. 1-180 180 p.Research output: Contribution to journal › Article › peer-review
- Published
Continuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis
Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A582Research output: Contribution to journal › Article › peer-review
- Published
Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A590Research output: Contribution to journal › Article › peer-review
- Published
Use Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients
Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A580Research output: Contribution to journal › Article › peer-review
- Published
Renal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment
Hagemi, A., Plumpton, C. & Hughes, D., 2 Oct 2017, In: BMC Nephrology. 18, 305.Research output: Contribution to journal › Article › peer-review
- Published
Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout
Plumpton, C., Alfirevic, A., Pirmohamed, M. & Hughes, D., 1 Oct 2017, In: Rheumatology. 56, 10, p. 1729-1739Research output: Contribution to journal › Article › peer-review
- Published
Cost-effectiveness of HLA-B*15:02 screening in Malaysia
Plumpton, C. & Hughes, D., Oct 2017, In: British Journal of Dermatology. 177, 4, p. 904-905Research output: Contribution to journal › Comment/debate
- Published
Cost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial
Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Sept 2017, In: Frontiers in Pharmacology. 8, 644.Research output: Contribution to journal › Article › peer-review
- Published
Carer-administration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARIAD)
Wilkinson, C., Poolman, M., Roberts, J., Wee, B., Hiscock, J., Hughes, D., Nelson, A., Perkins, P., Johnstone, R. P., Reymond, E., Foster, B., O'Connor, J., Jones, S., Hoare, Z., Roberts, R., Byrne, A., Healy, S. & Lewis, P., 1 Sept 2017.Research output: Contribution to conference › Poster › peer-review
- Published
Continuous subcutaneous insulin infusion compated to multiple daily injection regimens in children and yung people at diagnosis of type 1 diabetes: A pragmatic randomised controlled trial and economic evaluation (scipi trial)
Blair, J., Mckay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., John, G., Hughes, D. & Gamble, C., Sept 2017, p. 22-23.Research output: Contribution to conference › Abstract › peer-review
- Published
Using Routinely Recorded Data in the UK to Assess Outcomes in a Randomised Controlled Trial: The Trials of Access
Powell, G., Bonnett, L., Smith, C. T., Hughes, D., Williamson, P. & Marson, A., 23 Aug 2017, In: Trials. 18, 11 p., 389.Research output: Contribution to journal › Article › peer-review
- Published
Comparison of regression methods for the cost effectiveness analysis of clinical trials with a small population size: the sycamore and folated trials
Culeddu, G., Hughes, D. & Welton, N., 10 Jul 2017.Research output: Contribution to conference › Poster › peer-review
- Published
Affordable orphan drugs: A role for not-for-profit organisations
Davies, E. H., Fulton, E., Brook, D. & Hughes, D., Jul 2017, In: British Journal of Clinical Pharmacology. 83, 7, p. 1595-1601Research output: Contribution to journal › Article › peer-review
- Published
Patient preferences for outcomes in clinical trials: implications for medicines optimization
Holmes, E., Marson, A. G. & Hughes, D., 8 May 2017, In: Trials. 18 (Suppl 1), O18, p. 192 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
- Published
Core items for a standardised resource-use measure (ISRUM):expert Delphi consensus survey
Thorn, J., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., 7 May 2017, p. P265. 1 p.Research output: Contribution to conference › Poster › peer-review
- Published
Health economics analysis plans: the current state of play
Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 7 May 2017, p. P144. 1 p.Research output: Contribution to conference › Poster › peer-review
- Published
Patient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations
Ridyard, C. & Hughes, D., 7 May 2017, p. P141. 1 p.Research output: Contribution to conference › Poster › peer-review
- Published
Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis
Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., Hardwick, B., Hickey, H., Hughes, D., Woo, P., Benton, D., Edelsten, C. & Beresford, M. W., 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1637-1646Research output: Contribution to journal › Article › peer-review
- Published
Economic Studies in Motor Neurone Disease: A Systematic Methodological Review
Moore, A., Young, C. A. & Hughes, D., Apr 2017, In: Pharmacoeconomics. 35, 4, p. 397-413Research output: Contribution to journal › Article › peer-review
- Published
Societal perspective on access to publicly subsidised medicines: A cross sectional survey of 3080 adults in Australia
Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 1 Mar 2017, In: PLoS ONE.Research output: Contribution to journal › Article › peer-review
- 2016
- Published
A randomised, patient-assessor blinded, sham-controlled trial of external noninvasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial): study protocol for a randomised controlled trial
Johnson, S., Goebel, A., Richey, R., Holmes, E. & Hughes, D., 6 Dec 2016, In: Trials. 17, 574.Research output: Contribution to journal › Article › peer-review
- Published
Health Economics Analysis Plans: Where Are We Now?
Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 3 Nov 2016, p. A397. 1 p.Research output: Contribution to conference › Poster › peer-review
- Published
Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study
Hughes, D. & Poletti-Hughes, J., 21 Oct 2016, In: PLoS ONE. 11, 10, e0164681.Research output: Contribution to journal › Article › peer-review
- Published
Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden
Verhoef, T. I., Redekop, W. K., Langenskiold, S., Kamali, F., Wadelius, M., Burnside, G., Maitland-van der Zee, A. H., Hughes, D. & Pirmohamed, M., Oct 2016, In: The Pharmacogenomics Journal. 16, p. 478–484Research output: Contribution to journal › Article › peer-review
- Published
2016 Prof. John Urquhart Obituary
Breckenridge, A. & Hughes, D., Aug 2016, In: British Journal of Clinical Pharmacology. 82, 2, p. 573Research output: Contribution to journal › Letter › peer-review
- Published
A systematic review of economic evaluations of pharmacogenetic testing for prevention of adverse drug reactions
Plumpton, C. O., Roberts, D., Pirmohamed, M. & Hughes, D. A., Aug 2016, In: Pharmacoeconomics. 34, 8, p. 771-793Research output: Contribution to journal › Article › peer-review
- Published
A systematic review of patients' perspectives on the subcutaneous route of medication administration
Ridyard, C., Dawoud, D. M., Tuersley, L. V. & Hughes, D., Aug 2016, In: Patient: Patient–Centered Outcomes Research. 9, 4, p. 281-292Research output: Contribution to journal › Article › peer-review
- Published
What influences persistence with medicines? A multinational discrete choice experiment of 2549 patients
Holmes, E. A., Morrison, V. L. & Hughes, D., Aug 2016, In: British Journal of Clinical Pharmacology. 82, 2, p. 522-531Research output: Contribution to journal › Article › peer-review
- Published
Conducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches
Hughes, D., Charles, J. M., Dawoud, D. M., Edwards, R. T., Holmes, E. A., Jones, C. L., Parham, P., Plumpton, C., Ridyard, C. O., Lloyd-Williams, H., Wood, E. M. & Yeo, S., May 2016, In: Pharmacoeconomics. 34, 5, p. 447-461Research output: Contribution to journal › Article › peer-review
- Published
Impregnated central venous catheters for prevention of bloodstream infection in children (the CATCH trial): a randomised controlled trial
Gilbert, R. E., Mok, Q., Dwan, K., Harron, K., Moitt, T., Millar, M., Ramnarayan, P., Tibby, S. M., Hughes, D. & Gamble, C. F., 23 Apr 2016, In: The Lancet. 387, 10029, p. 1732-1742Research output: Contribution to journal › Article › peer-review
- Published
Opportunity costs and local health service spending decisions: a qualitative study from Wales
Schaffer, S. K., Sussex, J., Hughes, D. & Devlin, N., 25 Mar 2016, In: BMC Health Services Research. 16, 103Research output: Contribution to journal › Article › peer-review
- Published
Generalisability and Cost-Impact of Antibiotic-Impregnated Central Venous Catheters for Reducing Risk of Bloodstream Infection in Paediatric Intensive Care Units in England
Harron, K., Mok, Q., Hughes, D., Muller-Pebody, B., Parslow, R., Ramnarayan, P. & Gilbert, R., 21 Mar 2016, In: PLoS ONE. 11, 3, p. e0151348Research output: Contribution to journal › Article › peer-review
- Published
CATheter Infections in CHildren (CATCH): a randomised controlled trial and economic evaluation comparing impregnated and standard central venous catheters in children
Harron, K., Mok, Q., Dwan, K., Ridyard, C., Mott, T., Millar, M., Ramnarayan, P., Tibby, S. M., Muller-Pebody, B., Hughes, D., Gamble, C. & Gilbert, R. E., Mar 2016, In: Health Technology Assessment. 20, 18Research output: Contribution to journal › Article › peer-review
- Published
Multiple imputation of multiple multi-item scales when a full imputation model is infeasible
Hughes, D., Plumpton, C. O., Morris, T., Hughes, D. A. & White, I. R., 26 Jan 2016, In: BMC Research Notes. 9, 45, p. 1-15Research output: Contribution to journal › Article › peer-review
- 2015
- Published
The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial
Jenkinson, M. D., Javadpour, M., Haylock, B. J., Young, B., Gillard, H., Vinten, J., Bulbeck, H., Das, K., Farrell, M., Looby, S., Hickey, H., Preusser, M., Mallucci, C. L., Hughes, D., Gamble, C. & Weber, D. C., 14 Nov 2015, In: Trials. 16Research output: Contribution to journal › Article › peer-review
- Published
Identification Of Items For A Standardised Resource-Use Measure: Review Of Current Instruments
Thorn, J. C., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S. & Hollingworth, W., Nov 2015.Research output: Contribution to conference › Paper › peer-review
- Published
Evaluation of a consultant audit and feedback programme to improve the quality of antimicrobial prescribing in acute medical admissions
Hughes, D., Roberts, E., Dawoud, D. M., Hughes, D. A. & Cefai, C., 1 Oct 2015, In: International Journal of Pharmacy Practice. 23, 5, p. 333-339Research output: Contribution to journal › Article › peer-review
- Published
Rare Disease Terminology and Definitions—A Systematic Global Review: Report of the ISPOR Rare Disease Special Interest Group
Hughes, D., Richter, T., Nestler-Parr, S., Babela, R., Khan, Z. M., Tesoro, T., Molsen, E. & Hughes, D. A., 18 Aug 2015, In: Value in Health. 18, 6, p. 906-914Research output: Contribution to journal › Article › peer-review
- Published
‘Seizure First Aid Training’ for people with epilepsy who attend emergency departments, and their family and friends: study protocol for intervention development and a pilot randomised controlled trial
Noble, A. J., Marson, A. G., Tudur-Smith, C., Morgan, M., Hughes, D., Goodacre, S. & Ridsdale, L., 24 Jul 2015, In: BMJ Open. 5, 7Research output: Contribution to journal › Article › peer-review
- Published
Pharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery
Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Jul 2015, In: British Journal of Clinical Pharmacology. 80, 5, p. 1149-1159Research output: Contribution to journal › Article › peer-review
- Published
NICE recommendations: why no disinvestment recommendations to offset investment decisions?
Hughes, D., Tuersley, L. V., Hughes, D. A., Wood, E. M. & Tuersley, L., 19 May 2015, In: BMJ. 350Research output: Contribution to journal › Article › peer-review
- Published
Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria
Lotsch, F., Auer-Hackenberg, L., Groger, M., Rehman, K., Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., de Geest, S., Dobbels, F., Vrijens, B., Kardas, P., Hughes, D. & Ramharter, M., May 2015, In: Wiener klinische Wochenschrift. 127, 9-10, p. 379-384Research output: Contribution to journal › Article › peer-review
- Published
Study protocol for a randomised controlled trial of insulin delivery by continuous subcutaneous infusion compared to multiple daily injections
Blair, J., Gregory, J., Hughes, D., Ridyard, C., Gamble, C., McKay, A., Didi, M., Thornborough, K., Bedson, E., Awoyale, L., Cwiklinski, E. & Peak, M., 16 Apr 2015, In: Trials. 16, 163.Research output: Contribution to journal › Article › peer-review
- Published
Cost-effectiveness of screening for HLA-A*31:01 prior to initiation of carbamazepine in epilepsy
Plumpton, C., Yip, V. L. M., Alfirevic, A., Marson, A. G., Pirmohamed, M. & Hughes, D., Apr 2015, In: Epilepsia.Research output: Contribution to journal › Article › peer-review
- Published
Economic evaluation of a behavior-modifying intervention to enhance antiepileptic drug adherence
Hughes, D., Plumpton, C. O., Brown, I., Reuber, M., Marson, A. G. & Hughes, D. A., 26 Mar 2015, In: Epilepsy and Behavior. 45, p. 180-186Research output: Contribution to journal › Article › peer-review
- Published
Predictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey
Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Mar 2015, In: Value in Health. 18, 2, p. 206-216Research output: Contribution to journal › Article › peer-review
- Published
Climate influences on the cost-effectiveness of vector-based interventions against malaria in elimination scenarios
Hughes, D., Parham, P. E. & Hughes, D. A., 16 Feb 2015, In: Philosophical Transactions B: Biological Sciences. 370, 1665Research output: Contribution to journal › Article › peer-review
- Published
Taxonomy for methods of resource use measurement
DIRUM Team, 23 Jan 2015, In: Health Economics. 24, 3, p. 372-378Research output: Contribution to journal › Letter › peer-review
- Published
Review of resource-use measures in UK economic evaluations
Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (eds.). University of Kent, Canterbury, p. 22-31 10 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
- 2014
- Published
Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research
Holmes, E. A., Morrison, V. L. & Hughes, D., 8 Dec 2014, In: Value in Health. 17, 8, p. 863-876Research output: Contribution to journal › Article › peer-review
- Published
Does Electronic Monitoring Influence Adherence to Medication? Randomized Controlled Trial of Measurement Reactivity
Hughes, D., Sutton, S., Kinmonth, A. L., Hardeman, W., Hughes, D. A., Boase, S., Prevost, T., Kellar, I., Graffy, J., Griffin, S. & Farmer, A., 1 Dec 2014, In: Annals of Behavioral Medicine. 48, 3, p. 293-299Research output: Contribution to journal › Article › peer-review
- Published
Valuations of epilepsy-specific health states: a comparison of patients with epilepsy and the general population
Hughes, D., Mulhern, B., Rowen, D., Snape, D., Jacoby, A., Marson, T., Hughes, D. A., Baker, G. & Brazier, J., 1 Jul 2014, In: Epilepsy and Behavior. 36, p. 12-17Research output: Contribution to journal › Article › peer-review
- Published
Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation
Bedson, E., Bell, D., Carr, D., Carter, B., Hughes, D., Jorgensen, A., Lewis, H., Lloyd, K., McCaddon, A., Moat, S., Pink, J., Pirmohamed, M., Roberts, S., Russell, I., Sylvestre, Y., Tranter, R., Whitaker, R., Wilkinson, C. & Williams, N., Jul 2014, In: Health Technology Assessment. 18, 48, p. 1-159Research output: Contribution to journal › Article › peer-review
- Published
A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)
Hughes, D., Ramanan, A., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., Hickey, H., Hughes, D. A., Jones, A., Woo, P., Edelsten, C., Beresford, M. W. & The SYCAMORE Trail Management Group, N. V., 9 Jan 2014, In: Trials. 15, 14Research output: Contribution to journal › Article › peer-review
- Published
The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol
Hughes, D., Jenkinson, M. D., Gamble, C., Hartley, J. C., Hickey, H., Hughes, D. A., Blundell, M., Griffiths, M. J., Solomon, T. & Malluci, C. L., 3 Jan 2014, In: Trials. 15, 14Research output: Contribution to journal › Article › peer-review
- 2013
- Published
New advice on switching antiepileptic drugs might be a false economy
Holmes, E. A., Plumpton, C. O., Hughes, D., Holmes, E., Plumpton, C., Duerden, M., Marson, T. & Hughes, D. A., 16 Dec 2013, In: British Medical Journal. 347Research output: Contribution to journal › Article › peer-review
- Published
Interventions to improve osteoporosis medication adherence and persistence: a systematic review and literature appraisal by the ISPOR Medication Adherence & Persistence Special Interest Group
Hughes, D., Linck, P. G., Hiligsmann, M., Salas, M., Hughes, D. A., Manias, E., Gwadry-Sridhar, F. H., Linck, P. & Cowell, W., 1 Dec 2013, In: Osteoporosis International. 24, 12, p. 2907-2918Research output: Contribution to journal › Article › peer-review
- Published
A Systematic Review of Patient Preferences for Subcutaneous Medications
Ridyard, C., Dawoud, D. & Hughes, D., Nov 2013.Research output: Contribution to conference › Paper › peer-review
- Published
Cost effectiveness of pharmacogenetic screening prior to initiation of carbamazepine treatment for epilepsy
Plumpton, C. O., Yip, V., Alfirevic, A., Marson, A., Pirmohamed, M. & Hughes, D., Nov 2013, In: Value in Health. 16, 7, p. A624-A624Research output: Contribution to journal › Article › peer-review
- Published
Review of the Use of Resource Use Instruments Based on Patient Recall in Relation to Other Methods of Cost Estimation
Ridyard, C. & Hughes, D., Nov 2013.Research output: Contribution to conference › Paper › peer-review
- Published
Review of the use of resource use instruments based on patient recall in relation to other methods of resource use estimation
Ridyard, C. & Hughes, D., Nov 2013.Research output: Contribution to conference › Paper › peer-review
- Published
Screening log data can be used to inform protocol modifications, increasing patient recrutiment to a challanging clinical trial
Blair, J., Awoyale, L., Thornborough, K., Peak, M., Didi, M., Bedson, E., Hughes, D., Ridyard, C., Tat, T. & Gregory, J., Nov 2013.Research output: Contribution to conference › Paper › peer-review
- Published
Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation
Hughes, D., Pink, J., Pirmohamed, M., Lane, S. & Hughes, D. A., 23 Sept 2013, In: Clinical Pharmacology and Therapeutics.Research output: Contribution to journal › Article › peer-review
- Published
Societal views on NICE, cancer drugs fund and value-based pricing criteria for prioritising medicines: a cross-sectional survey of 4118 adults in Great Britain
Hughes, D., Linley, W. G. & Hughes, D. A., 1 Aug 2013, In: Health Economics. 22, 8, p. 948-964Research output: Contribution to journal › Article › peer-review
- Published
Impact of Interventions on Medication Adherence and Blood Pressure Control in Patients with Essential Hypertension: A Systematic Review by the ISPOR Medication Adherence and Persistence Special Interest Group
Hughes, D., Gwadry-Sridhar, F. H., Manias, E., Lal, L., Salas, M., Hughes, D. A., Ratzki-Leewing, A. & Grubisic, M., 1 Jul 2013, In: Value in Health. 16, 5, p. 863-871Research output: Contribution to journal › Article › peer-review
- Published
Resource-Use Measurement Based on Patient Recall: Issues and Challenges for Economic Evaluation
Thorn, J. C., Coast, J., Cohen, D., Hollingworth, W., Knapp, M., Noble, S. M., Ridyard, C. H., Wordsworth, S. & Hughes, D., 1 Jun 2013, In: Applied Health Economics and Health Policy. 11, 3, p. 155-161Research output: Contribution to journal › Article › peer-review
- Published
Identification and Assessment of Adherence-Enhancing Interventions in Studies Assessing Medication Adherence Through Electronically Compiled Drug Dosing Histories: A Systematic Literature Review and Meta-Analysis
Hughes, D., Holmes, E. A., Demonceau, J., Ruppar, T., Kristano, P., Hughes, A. D., Fargher, E., Przemyslaw, K., De Geest, S., Dobbels, F., Lewek, P., Urquhart, J. & Vrijens, B., 1 May 2013, In: Drugs. 73, 6, p. 545-562Research output: Contribution to journal › Article › peer-review
- Published
Comparative Effectiveness of Dabigatran, Rivaroxaban, Apixaban, and Warfarin in the Management of Patients With Nonvalvular Atrial Fibrillation
Hughes, D., Pink, J., Pirmohamed, M. & Hughes, D. A., 25 Apr 2013, In: Clinical Pharmacology and Therapeutics.Research output: Contribution to journal › Article › peer-review
- Published
Decision-Makers’ Preferences for Approving New Medicines in Wales: A Discrete-Choice Experiment with Assessment of External Validity
Hughes, D., Linley, W. G. & Hughes, D. A., 1 Apr 2013, In: Pharmacoeconomics. 31, 4, p. 345-355Research output: Contribution to journal › Article › peer-review
- Published
Adherence and variability in warfarin dose requirements: assessment in a prospective cohort
Hughes, D., Jorgensen, A. L., Hughes, D. A., Hanson, A., van Eker, D., Toh, C. H., Pirmohamed, M. & Williamson, P. R., 1 Jan 2013, In: Pharmacogenomics. 14, 2, p. 151-163Research output: Contribution to journal › Article › peer-review
- Published
Pharmacogenetic tests: the need for a level playing field
Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4Research output: Contribution to journal › Article › peer-review
- 2012
- Published
Challenges in the Development and Reimbursement of Personalized Medicine—Payer and Manufacturer Perspectives and Implications for Health Economics and Outcomes Research: A Report of the ISPOR Personalized Medicine Special Interest Group
Hughes, D., Faulkner, E., Annemans, L., Garrison, L., Helfand, M., Holtorf, A. P., Hornberger, J., Hughes, D. A., Li, T., Malone, D., Payne, K., Siebert, U., Towse, A., Veenstra, D. & Watkins, J., 1 Dec 2012, In: Value in Health. 15, 8, p. 1162-1171Research output: Contribution to journal › Article › peer-review
- Published
Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs
Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417Research output: Contribution to journal › Article › peer-review
- Published
Reimbursement Decisions of the All Wales Medicines Strategy Group
Hughes, D., Linley, W. G. & Hughes, D. A., 1 Sept 2012, In: PharmoEconomics. 30, 9, p. 779-794Research output: Contribution to journal › Article › peer-review
- Published
Development of a Database of Instruments for Resource-Use Measurement: Purpose, Feasibility, and Design
DIRUM Team, 1 Jul 2012, In: Value in Health. 15, 5, p. 650-655Research output: Contribution to journal › Article › peer-review