Professor Dyfrig Hughes
Athro mewn Ffarmacoeconomeg / Cyfarwyddwr Ymchwil
- 2019
- Cyhoeddwyd
Medicines Shortages in the United Kingdom
Hughes, D., Hyd 2019, Yn: Clinical Pharmacology and Therapeutics. 106, 4, t. 712Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid
- Cyhoeddwyd
Challenges for economic evaluation of strategies to contain antimicrobial resistance
Holmes, E. & Hughes, D., 27 Medi 2019, Yn: Antibiotics. 8, 4, 8 t., 166.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Sylw/Dadl › adolygiad gan gymheiriaid
- Cyhoeddwyd
A Fully Integrated Real-Time Detection, Diagnosis, and Control of Community Diarrheal Disease Clusters and Outbreaks (the INTEGRATE Project): Protocol for an Enhanced Surveillance System
McIntyre, K. M., Bolton, F. J., Christley, R. M., Cleary, P., Deja, E., Durie, A. E., Diggle, P. J., Hughes, D., de Lusignan, S., Orton, L., Radford, A. D., Elliot, A., Smith, G. E., Snape, D. A., Stanistreet, D., Vivancos, R., Winstanley, C. & O'Brien, S. J., 26 Medi 2019, Yn: JMIR Research Protocols. 8, 9, t. e13941 10 t., e13941.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Evidence to support inclusion of pharmacogenetic biomarkers in randomised controlled trials
Johnson, D., Jorgensen, A., Hughes, D. & Pirmohamed, M., 1 Medi 2019, Yn: Journal of Personalized Medicine. 9, 3, 19 t., 42.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl adolygu › adolygiad gan gymheiriaid
- Cyhoeddwyd
Integration of Pharmacometrics and Pharmacoeconomics to Quantify the Value of Improved Forgiveness to Nonadherence: A Case Study of Novel Xanthine Oxidase Inhibitors for Gout
Hill McManus, D., Marshall, S., Soto, E. & Hughes, D., Medi 2019, Yn: Clinical Pharmacology and Therapeutics. 106, 3, t. 652-660Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Cost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework
Plumpton, C., Pirmohamed, M. & Hughes, D., Meh 2019, Yn: Clinical Pharmacology and Therapeutics. 105, 6, t. 1429-1438Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Improving Medication Adherence Research Reporting: European Society for Patient Adherence, Compliance and Persistence Medication Adherence Reporting Guideline
de Geest, S., Zullig, L., Dunbar-Jacobs, J., Hughes, D., Wilson, I. & Vrijens, B., Meh 2019, Yn: Journal of Cardiovascular Nursing. 34, 3, t. 199-200Allbwn ymchwil: Cyfraniad at gyfnodolyn › Golygyddiad › adolygiad gan gymheiriaid
- Cyhoeddwyd
What really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK
Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Meh 2019, Yn: Epilepsy and Behavior. 95, t. 181-191Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus
Crudgington, H., Rogers, M., Bray, L., Carter, B., Currier, J., Gibbon, F., Hughes, D., Lyle, S., Roberts, D., Smith, C. T., Gringras, P., Pal, D. & Morris, C., Mai 2019, Yn: Epilepsia. 60, 5, t. 857-871Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT
Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D., McKay, A., Rosala_Hanna, A., Williamson, P. R., Hardwick, B., Hickey, H., Rainford, N., Kolamunnage-Dona, R., Culeddu, G., Plumpton, C., Wood, E., Compeyrot-Lacassagne, S., Woo, P., Eldesten, C. & Beresford, M. W., 10 Ebr 2019, Yn: Health Technology Assessment. 23, 15, t. 1-174 174 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Continuous subcutaneous insulin infusion versus multiple daily injection regimens in children and young people at diagnosis of type 1 diabetes: pragmatic randomised controlled trial and economic evaluation
Blair, J. C., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. A. & Gamble, C., 3 Ebr 2019, Yn: British Medical Journal. 365, t. l1226 l1226.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE)
de Geest, S., Zullig, L. L., Dunbar-Jacob, J., Hughes, D., Wilson, I. & Vrijens, B., 1 Ebr 2019, Yn: European Journal of Cardiovascular Nursing. 18, 4, t. 258-259 2 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Golygyddiad › adolygiad gan gymheiriaid
- Cyhoeddwyd
Systematic Review: Outcomes and adverse events from randomised trials in Crohn's disease
Catt, H., Hughes, D., Kirkham, J. K. & Bodger, K., Ebr 2019, Yn: Alimentary Pharmacology and Therapeutics. 49, 8, t. 978-996 19 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis
Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Maw 2019, Yn: Ophthalmology. 126, 3, t. 415-424Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.
Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Maw 2019, Yn: Ophthalmology. 126, 3, t. e24-e25Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid
- Cyhoeddwyd
Patient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs
Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Maw 2019, Yn: Clinical Pharmacology and Therapeutics. 105, 3, t. 672-683 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
CARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial
Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Chwef 2019, Yn: Trials. 20, 1, 16 t., 105.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Community views on factors affecting medicines resource allocation: Cross-sectional survey of 3080 adults in Australia
Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 2019, Yn: Australian Health Review . 43, 3, t. 254-260Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- 2018
- Cyhoeddwyd
Cost-Effectiveness Analysis of the Use of Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing in Primary Care
Holmes, E., Harris, S. D., Hughes, A., Craine, N. & Hughes, D., 7 Rhag 2018, Yn: Antibiotics. 7, 4, 19 t., 106.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Impact of non-adherence and flare resolution on the cost effectiveness of treatments for gout: Application of a linked pharmacometric/pharmacoeconomic model
Hill-McManus, D., Marshall, S., Soto, E., Lane, S. & Hughes, D., Rhag 2018, Yn: Value in Health. 21, 12, t. 1373-1381Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Mapping ALSFRS-R and ALSUI to EQ-5D in patients with motor neurone disease
Moore, A., Young, C. A. & Hughes, D., Tach 2018, Yn: Value in Health. 21, 11, t. 1322-1329Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care
Swift, B., Jain, L., White, C., Chandrasekaran, V., Bhandari, A., Hughes, D. & Jadhav, P., Medi 2018, Yn: Clinical and Translational Science. 11, 5, t. 450-460 11 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Letter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma
Jenkinson, M., Weber, D., Haylock, B., Sherratt, F., Young, B., Weller, M., Bulbeck, H., Culeddu, G., Hughes, D., Brain, A., Das, K., Preusser, M., Francis, P. & Gamble, C., 17 Awst 2018, Yn: Journal of Neurology, Neurosurgery and Psychiatry.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid
- Cyhoeddwyd
Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT
Blair, J., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. & Gamble, C., Awst 2018, Yn: Health Technology Assessment. 22, 42, t. 1-112 112 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Lessons learnt from a discontinued randomised controlled trial: Adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC)
Williams, N., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Gorff 2018, Yn: Trials. 19, 408.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
ESPACOMP Medication Adherence Reporting Guideline (EMERGE)
De Geest, S., Zullig, L. L., Dunbar-Jacob, J., Helmy, R., Hughes, D., Wilson, I. & Vrijens, B., 3 Gorff 2018, Yn: Annals of Internal Medicine. 169, 1, t. 30-35Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Do guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review
Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Gorff 2018, Yn: Thorax. 73, 7, t. 670-673Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr › adolygiad gan gymheiriaid
- Cyhoeddwyd
Core items for a standardized resource-use measure (ISRUM): expert Delphi consensus survey
Thom, J., Brookes, S. T., Ridyard, C., Riley, R., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., Meh 2018, Yn: Value in Health. 21, 6, t. 640-649Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Societal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods
Bourke, S. M., Plumpton, C. & Hughes, D., 9 Mai 2018, Yn: Value in Health. 21, 5, t. 538-546Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Economics of pharmacogenetic guided treatments: Underwhelming or overstated?
Hughes, D., Mai 2018, Yn: Clinical Pharmacology and Therapeutics. 103, 5, t. 749-751Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes
Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., Mai 2018, Yn: Pharmacoeconomics. 36, 5, t. 613-624 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Rare disease prevention and treatment: The need for a level playing field
Hughes, D. & Plumpton, C., Chwef 2018, Yn: Pharmacogenomics. 19, 3, t. 243-247Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Impact of non-adherence on the safety and efficacy of uric acid lowering therapies in the treatment of gout
Hill McManus, D., Soto, E., Marshall, S., Lane, S. & Hughes, D., Ion 2018, Yn: British Journal of Clinical Pharmacology. 84, 1, t. 142-152Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Impact on the phased abolition of co-payments on the utilisation of selected prescription medicines in Wales
Alam, M. F., Cohen, D., Dunstan, F., Hughes, D. & Routledge, P. A., Ion 2018, Yn: Health Economics. 27, 1, t. 236-243Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- 2017
- Cyhoeddwyd
Decision analytic modelling methods for the assessing the effectiveness of treatment sequences for clinical and economic decision making: a methodological review
Lewis, R., Hughes, D. & Wilkinson, C., 30 Tach 2017, Yn: Value in Health. 20, 9, t. A748 1 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., Tach 2017, Yn: Value in Health. 20, 9, t. A481 - A482Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica
Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Hyd 2017, Yn: Health Technology Assessment. 21, 60, t. 1-180 180 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Continuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis
Ridyard, C., Blair, J. & Hughes, D., 20 Hyd 2017, Yn: Value in Health. 20, 9, t. A582Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., 20 Hyd 2017, Yn: Value in Health. 20, 9, t. A590Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Use Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients
Ridyard, C., Blair, J. & Hughes, D., 20 Hyd 2017, Yn: Value in Health. 20, 9, t. A580Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Renal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment
Hagemi, A., Plumpton, C. & Hughes, D., 2 Hyd 2017, Yn: BMC Nephrology. 18, 305.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout
Plumpton, C., Alfirevic, A., Pirmohamed, M. & Hughes, D., 1 Hyd 2017, Yn: Rheumatology. 56, 10, t. 1729-1739Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Influence Of Disease Familiarity On Implied Time Preferences For Seizure Frequency Reduction.
Holmes, E., Morrison, V. & Hughes, D., 1 Hyd 2017, Yn: Value in Health. 20, 9, PA689.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Crynodeb Cyfarfod › adolygiad gan gymheiriaid
- Cyhoeddwyd
Cost-effectiveness of HLA-B*15:02 screening in Malaysia
Plumpton, C. & Hughes, D., Hyd 2017, Yn: British Journal of Dermatology. 177, 4, t. 904-905Allbwn ymchwil: Cyfraniad at gyfnodolyn › Sylw/Dadl
- Cyhoeddwyd
Cost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial
Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Medi 2017, Yn: Frontiers in Pharmacology. 8, 644.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Carer-administration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARIAD)
Wilkinson, C., Poolman, M., Roberts, J., Wee, B., Hiscock, J., Hughes, D., Nelson, A., Perkins, P., Johnstone, R. P., Reymond, E., Foster, B., O'Connor, J., Jones, S., Hoare, Z., Roberts, R., Byrne, A., Healy, S. & Lewis, P., 1 Medi 2017.Allbwn ymchwil: Cyfraniad at gynhadledd › Murlen › adolygiad gan gymheiriaid
- Cyhoeddwyd
Continuous subcutaneous insulin infusion compated to multiple daily injection regimens in children and yung people at diagnosis of type 1 diabetes: A pragmatic randomised controlled trial and economic evaluation (scipi trial)
Blair, J., Mckay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., John, G., Hughes, D. & Gamble, C., Medi 2017, t. 22-23.Allbwn ymchwil: Cyfraniad at gynhadledd › Crynodeb › adolygiad gan gymheiriaid
- Cyhoeddwyd
Using Routinely Recorded Data in the UK to Assess Outcomes in a Randomised Controlled Trial: The Trials of Access
Powell, G., Bonnett, L., Smith, C. T., Hughes, D., Williamson, P. & Marson, A., 23 Awst 2017, Yn: Trials. 18, 11 t., 389.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
- Cyhoeddwyd
Comparison of regression methods for the cost effectiveness analysis of clinical trials with a small population size: the sycamore and folated trials
Culeddu, G., Hughes, D. & Welton, N., 10 Gorff 2017.Allbwn ymchwil: Cyfraniad at gynhadledd › Murlen › adolygiad gan gymheiriaid
- Cyhoeddwyd
Affordable orphan drugs: A role for not-for-profit organisations
Davies, E. H., Fulton, E., Brook, D. & Hughes, D., Gorff 2017, Yn: British Journal of Clinical Pharmacology. 83, 7, t. 1595-1601Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid