Professor Dyfrig Hughes
Athro mewn Ffarmacoeconomeg / Cyfarwyddwr Ymchwil
![](https://research.bangor.ac.uk/portal/files/28327363/Dyfrig_Hughes.jpg)
- Published
Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial
Brogan, P. A., Arch, B., Hickey, H., Anton, J., Iglesias, E., Baildam, E., Mahmood, K., Cleary, G., Moraitis, E., Papadopoulou, C., Beresford, M. W., Riley, P., Demir, S., Ozen, S., Culeddu, G., Hughes, D., Dolezalova, P., Hampson, L., Whitehead, J., Jayne, D., Ruperto, N., Tudor-Smith, C. & Eleftheriou, D., Sept 2021, In: Arthritis and Rheumatology. 73, 9, p. 1673-1682Research output: Contribution to journal › Article › peer-review
- Published
NICE and new: appraising innovation.
Hughes, D., Ferner, R. E., Hughes, D. A. & Aronson, J. K., 5 Jan 2010, In: British Medical Journal. 340, p. b5493Research output: Contribution to journal › Article › peer-review
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NICE recommendations: why no disinvestment recommendations to offset investment decisions?
Hughes, D., Tuersley, L. V., Hughes, D. A., Wood, E. M. & Tuersley, L., 19 May 2015, In: BMJ. 350Research output: Contribution to journal › Article › peer-review
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New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes
Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., May 2018, In: Pharmacoeconomics. 36, 5, p. 613-624 12 p.Research output: Contribution to journal › Article › peer-review
- Published
New advice on switching antiepileptic drugs might be a false economy
Holmes, E. A., Plumpton, C. O., Hughes, D., Holmes, E., Plumpton, C., Duerden, M., Marson, T. & Hughes, D. A., 16 Dec 2013, In: British Medical Journal. 347Research output: Contribution to journal › Article › peer-review
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New drugs for old: disinvestment and NICE.
Hughes, D., Hughes, D. A. & Ferner, R. E., 25 Feb 2010, In: British Medical Journal. 340, p. c572Research output: Contribution to journal › Article › peer-review
- Published
Non-compliance with antibiotic therapy for acute community infections: A global survey.
Hughes, D., Pechere, J. C., Hughes, D. A., Kardas, P. & Cornaglia, G., 1 Mar 2007, In: International Journal of Antimicrobial Agents. 29, 3, p. 245-253Research output: Contribution to journal › Article › peer-review
- Published
Novel oral iron therapy for iron deficiency anaemia: How to value safety in a new drug?
Culeddu, G., Su, L., Chen, Y., Pereira, D. I. A., Powell, J. J. & Hughes, D., Mar 2022, In: British Journal of Clinical Pharmacology. 88, 3, p. 1347-1357 11 p.Research output: Contribution to journal › Article › peer-review
- Published
Nurse-led vs. conventional physician-led follow-up for patients with cancer: systematic review
Lewis, R., Neal, R. D., Williams, N. H., France, B., Wilkinson, C. E., Hendry, M., Russell, D., Russell, I., Hughes, D., Stuart, N. S. & Weller, D., 1 Apr 2009, In: Journal of Advanced Nursing. 65, 4, p. 706-723Research output: Contribution to journal › Article › peer-review
- Published
Opportunity costs and local health service spending decisions: a qualitative study from Wales
Schaffer, S. K., Sussex, J., Hughes, D. & Devlin, N., 25 Mar 2016, In: BMC Health Services Research. 16, 103Research output: Contribution to journal › Article › peer-review
- Published
Orphan drug treatments: economic considerations
Hughes, D. & Hughes, D. A., 1 Nov 2007.Research output: Contribution to conference › Paper
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Orphan drugs revisited: author's response.
Hughes, D. & Hughes, D. A., 1 May 2006, In: Quarterly Journal of Medicine. 99, 5, p. 350-351Research output: Contribution to journal › Article › peer-review
- Published
Parenting programme for parents of children at risk of developing conduct disorder: cost effectiveness analysis.
Bywater, T. J., Hutchings, J. M., Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 31 Mar 2007, In: British Medical Journal. 334, 7595, p. 682-685Research output: Contribution to journal › Article › peer-review
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Patient compliance and persistence with prescribed medication: Measurement and health economic impact
Hughes, D., Koncz, T., Hughes, D. A., Cleemput, I. & Annemans, L., 1 May 2004.Research output: Contribution to conference › Paper
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Patient compliance and pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Oct 2001.Research output: Contribution to conference › Paper
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Patient compliance and pharmacoeconomics
Hughes, D. & Hughes, D. A., 1 Nov 2002.Research output: Contribution to conference › Paper
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Patient preferences for outcomes in clinical trials: implications for medicines optimization
Holmes, E., Marson, A. G. & Hughes, D., 8 May 2017, In: Trials. 18 (Suppl 1), O18, p. 192 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
- Published
Patient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs
Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Mar 2019, In: Clinical Pharmacology and Therapeutics. 105, 3, p. 672-683 12 p.Research output: Contribution to journal › Article › peer-review
- E-pub ahead of print
Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study
Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L., 9 Apr 2024, (E-pub ahead of print) In: ACR Open Rheumatology.Research output: Contribution to journal › Article › peer-review
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Patient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations
Ridyard, C. & Hughes, D., 7 May 2017, p. P141. 1 p.Research output: Contribution to conference › Poster › peer-review
- Published
Patients' and healthcare professionals' views of cancer follow-up: systematic review
Lewis, R., Neal, R. D., Hendry, M., France, B., Williams, N. H., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., Jul 2009, In: British Journal of General Practice. 59, 564, p. e248-e259Research output: Contribution to journal › Article › peer-review
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Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A590Research output: Contribution to journal › Article › peer-review
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Perceptions of European ME/CFS experts concerning knowledge and understanding of ME/CFS among primary care physicians in Europe: A report from the European ME/CFS Research Network (EUROMENE)
Cullinan, J., Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 26 Feb 2021, In: Medicina. 57, 3, 208.Research output: Contribution to journal › Article › peer-review
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Pharmacoeconomic evaluations in Ireland, Scotland and Wales: A Celtic perspective on pharmaceutical assessment
Hughes, D., Hughes, D. A., Drummond, M., Tolley, K. & Ryan, M., 1 Oct 2007.Research output: Contribution to conference › Paper
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Pharmacoeconomic models that incorporate non-compliance
Hughes, D. & Hughes, D. A., 1 Jul 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomics appraisals by the all Wales medicines strategy group
Hughes, D. & Hughes, D. A., 1 Jul 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomics in Wales: functions of the all Wales medicines strategy group
Hughes, D. & Hughes, D. A., 1 Apr 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomics of pharmacogenetic testing: azathioprine
Hughes, D., McAllister, R. & Hughes, D. A., 1 Apr 2004.Research output: Contribution to conference › Paper
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Pharmacoeconomics: principles and relevance to the activities of drug and therapeutics committees.
Hughes, D., Hughes, D. A. & Reynolds, D. J., 1 Oct 2009, In: Clinical Medicine. 9, 5, p. 490-492Research output: Contribution to journal › Article › peer-review
- Published
Pharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery
Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Jul 2015, In: British Journal of Clinical Pharmacology. 80, 5, p. 1149-1159Research output: Contribution to journal › Article › peer-review
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Pharmacogenetic tests: the need for a level playing field
Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4Research output: Contribution to journal › Article › peer-review
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Pharmacogenomics spotlight commentary: From the United Kingdom to global populations
Magavern, E. F., Daly, A. K., Gilchrist, A. & Hughes, D., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4546-4548 3 p., 14917.Research output: Contribution to journal › Comment/debate › peer-review
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Pharmacokinetic-Pharmacodynamic modelling of Lapdap (CPG-DDS) combination.
Hughes, D., Hughes, D. A., Watkins, B. & Winstanley, P., 1 Jan 2001, 2001 ed. Unknown.Research output: Book/Report › Commissioned report
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Pharmacokinetics, patient compliance and pharmaeconomics
Hughes, D. & Hughes, D. A., 1 Jun 2005.Research output: Contribution to conference › Paper
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Pharmacometric analysis of duration of drug action: implications for improved forgiveness to medication non-compliance
Hughes, D., Hughes, D. A. & Walley, T., 1 Sept 2001.Research output: Contribution to conference › Paper
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Physchiatrist prescribing preferences and attitudes toward promotion
Hughes, D., Menkes, D., Davies, R. & Hughes, D. A., 1 Apr 2006.Research output: Contribution to conference › Paper
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Plasma Methylmalonic Acid Concentration in Folic Acid–Supplemented Depressed Patients with Low or Marginal Vitamin B-12: A Randomized Trial
Carter, B., Zenasni, Z., Moat, S. J., Hudson, P. R., Russell, I. T., McCaddon, A., Whitaker, R., Pink, J., Roberts, S., Wilkinson, C., Hughes, D., Betson, E., Carr, D., Jorgenson, A., Pirmohamed, M., Williams, N., Lewis, H., Lloyd, K., Sylvesture, Y. & Tranter, R., Dec 2021, In: Journal of Nutrition. 151, 12, p. 3738-3745 8 p.Research output: Contribution to journal › Article › peer-review
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Policy on ultra-orphan drugs.
Hughes, D. & Hughes, D. A., 1 Jan 2007, 2007 ed. Unknown.Research output: Book/Report › Commissioned report
- Published
Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone.
Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, G., Watkins, W. A. & Ward, S., 1 Mar 2006, In: British Journal of Clinical Pharmacology. 61, 3, p. 289-300Research output: Contribution to journal › Article › peer-review
- Published
Population pharmacokinetics of warfarin: Intermin analysis of the Liverpool pharmacogenetic prospective cohort study
Hughes, D., Matthews, I., Aarons, L., Al-Zubiedi, S., Hatch, E., Lane, S., Williamson, P., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Nov 2007.Research output: Contribution to conference › Paper
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PrEP use, sexual behaviour, and PrEP adherence among men who have sex with men living in Wales prior to and during the COVID-19 pandemic
Gillespie, D., Couzens, Z., de Bruin, M., Hughes, D., Jones, A., Ma, R., Williams, A., Wood, F. & Blee, K., Aug 2022, In: AIDS and Behavior. 26, 8, p. 2746-2757 12 p.Research output: Contribution to journal › Article › peer-review
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Pragmatic trials - design features and implications for clinical decision making
Hughes, D., Urdahl, H., Hughes, D. A. & Freemantle, N., 1 Aug 2000.Research output: Contribution to conference › Paper
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Predicting "real world" effectiveness by integrating adherence with pharmacodynamic modelling.
Hughes, D., Hughes, D. A. & Walley, T., 1 Jul 2003, In: Clinical Pharmacology and Therapeutics. 74, 1, p. 1-8Research output: Contribution to journal › Article › peer-review
- Published
Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research
Holmes, E. A., Morrison, V. L. & Hughes, D., 8 Dec 2014, In: Value in Health. 17, 8, p. 863-876Research output: Contribution to journal › Article › peer-review
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Predictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey
Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Mar 2015, In: Value in Health. 18, 2, p. 206-216Research output: Contribution to journal › Article › peer-review
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Prescription fee exemption research study
Hughes, D., Myles, S., Hughes, D. A., Routledge, P. & Wales, D. F., 1 Jun 2006.Research output: Contribution to conference › Paper
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Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study
Hughes, D. & Poletti-Hughes, J., 21 Oct 2016, In: PLoS ONE. 11, 10, e0164681.Research output: Contribution to journal › Article › peer-review
- Published
Psychometric properties of an adapted stigma scale and experiences of stigma associated with HIV pre-exposure prophylaxis use among men who have sex with men: a mixed methods study
Gillespie, D. & Hughes, D., Jul 2023, In: AIDS and Behavior. 27, 7, p. 2397-2410 14 p.Research output: Contribution to journal › Article › peer-review
- Published
Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 11 Nov 2005, In: Value in Health. 8, 6, p. A192Research output: Contribution to journal › Article › peer-review
- Published
Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Nov 2005.Research output: Contribution to conference › Paper
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Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Nov 2005.Research output: Contribution to conference › Paper
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Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Jan 2006.Research output: Contribution to conference › Paper
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Public funding of drugs for orphan diseases
Hughes, D. & Hughes, D. A., 1 Jul 2005.Research output: Contribution to conference › Paper
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Public health interventions to promote mental well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.
Hughes, D., Windle, G., Hughes, D. A., Linck, P., Morgan, R., Burholt, V., Edwards, R. T., Reeves, C., Yeo, S. T., Woods, R. T. & Russell, I. T., 1 Jan 2007, 2007 ed. Unknown.Research output: Book/Report › Commissioned report
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Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.
Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T., Morgan, R., Woods, R. T., Burholt, V., Edwards, R. T., Reeves, C. & Yeo, S. T., 1 Jan 2008, 2008 ed. Unknown.Research output: Book/Report › Commissioned report
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Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness: Evidence Tables.
Hughes, D., Linck, P. G., Windle, G., Linck, P., Morgan, R., Hughes, D. A., Burholt, V., Reeves, C., Yeo, S. T., Woods, R. T., Edwards, R. T. & Russell, I. T., 1 Jan 2008, 2008 ed. Unknown.Research output: Book/Report › Commissioned report
- Published
Public meetings of the NICE appraisals committee
Hughes, D. & Hughes, D. A., 1 Dec 2007.Research output: Contribution to conference › Paper
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Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., Nov 2017, In: Value in Health. 20, 9, p. A481 - A482Research output: Contribution to journal › Article › peer-review
- Published
Quantitative evidence synthesis methods for the assessment of the effectiveness of treatment sequences for clinical and economic decision-making: a review and taxonomy of simplifying assumptions
Lewis, R., Hughes, D., Sutton, AJ. & Wilkinson, C., Jan 2021, In: PharmacoEconomics. 39, 1, p. 25-61 37 p.Research output: Contribution to journal › Article › peer-review
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Quantitative risk-benefit analysis
Hughes, D. & Hughes, D. A., 1 May 2007.Research output: Contribution to conference › Paper
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RES00019. Wales COVID-19 Evidence Centre. A rapid evidence summary indicating the evidence of the inverse care law in social care in Wales and has this been exacerbated by the COVID-19 pandemic?
Spencer, L., Hendry, A., Makanjuola, A., Hughes, D., Wilkinson, C., Pisavadia, K., Davies, J., Fitzsimmons, D. & Edwards, R. T., Feb 2022, Welsh Government. 33 p.Research output: Book/Report › Other report
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RES00038. Wales COVID-19 Evidence Centre. A rapid evidence summary of the cost impact of Long COVID on employment and caring responsibilities
Spencer, L., Hendry, A., Davies, J., Pisavadia, K., Hughes, D. & Edwards, R. T., May 2022, Welsh Government. 18 p.Research output: Book/Report › Other report
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Rare Disease Terminology and Definitions—A Systematic Global Review: Report of the ISPOR Rare Disease Special Interest Group
Hughes, D., Richter, T., Nestler-Parr, S., Babela, R., Khan, Z. M., Tesoro, T., Molsen, E. & Hughes, D. A., 18 Aug 2015, In: Value in Health. 18, 6, p. 906-914Research output: Contribution to journal › Article › peer-review
- Published
Rare disease prevention and treatment: The need for a level playing field
Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247Research output: Contribution to journal › Article › peer-review
- Published
Rationing of drugs for rare diseases
Hughes, D. & Hughes, D. A., 1 Apr 2006.Research output: Contribution to conference › Paper
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Rationing of drugs for rare diseases.
Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 4, p. 315-316Research output: Contribution to journal › Article › peer-review
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Reimbursement Decisions of the All Wales Medicines Strategy Group
Hughes, D., Linley, W. G. & Hughes, D. A., 1 Sept 2012, In: PharmoEconomics. 30, 9, p. 779-794Research output: Contribution to journal › Article › peer-review
- Published
Renal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment
Hagemi, A., Plumpton, C. & Hughes, D., 2 Oct 2017, In: BMC Nephrology. 18, 305.Research output: Contribution to journal › Article › peer-review
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Resource-Use Measurement Based on Patient Recall: Issues and Challenges for Economic Evaluation
Thorn, J. C., Coast, J., Cohen, D., Hollingworth, W., Knapp, M., Noble, S. M., Ridyard, C. H., Wordsworth, S. & Hughes, D., 1 Jun 2013, In: Applied Health Economics and Health Policy. 11, 3, p. 155-161Research output: Contribution to journal › Article › peer-review
- Published
Review of resource-use measures in UK economic evaluations
Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (eds.). University of Kent, Canterbury, p. 22-31 10 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
- Published
Review of the Use of Resource Use Instruments Based on Patient Recall in Relation to Other Methods of Cost Estimation
Ridyard, C. & Hughes, D., Nov 2013.Research output: Contribution to conference › Paper › peer-review
- Published
Review of the use of resource use instruments based on patient recall in relation to other methods of resource use estimation
Ridyard, C. & Hughes, D., Nov 2013.Research output: Contribution to conference › Paper › peer-review
- Published
Screening log data can be used to inform protocol modifications, increasing patient recrutiment to a challanging clinical trial
Blair, J., Awoyale, L., Thornborough, K., Peak, M., Didi, M., Bedson, E., Hughes, D., Ridyard, C., Tat, T. & Gregory, J., Nov 2013.Research output: Contribution to conference › Paper › peer-review
- Published
Seizure First Aid Training For people with Epilepsy (SAFE) frequently attending emergency departments and their significant others: results of a UK multi-centre randomised controlled pilot trial
Noble, A. J., Snape, D., Nevitt, S., Holmes, E., Morgan, M., Smith, C. T., Hughes, D., Buchanan, M., McVicar, J., MacCallum, E., Goodacre, S., Rinsdale, L. & Marson, A. G., 16 Apr 2020, In: BMJ Open. 10, 4, e035516.Research output: Contribution to journal › Article › peer-review
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Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project
Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 17-27 11 p.Research output: Contribution to journal › Article › peer-review
- Published
Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT
Mallucci, C. L., Jenkinson, M., Conroy, E. J., Hartley, J. C., Brown, M., Moitt, T., Dalton, J., Kearns, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 2 Apr 2020, In: Health Technology Assessment. 24, 17, 114 p.Research output: Contribution to journal › Article › peer-review
- Published
Societal perspective on access to publicly subsidised medicines: A cross sectional survey of 3080 adults in Australia
Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 1 Mar 2017, In: PLoS ONE.Research output: Contribution to journal › Article › peer-review
- Published
Societal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods
Bourke, S. M., Plumpton, C. & Hughes, D., 9 May 2018, In: Value in Health. 21, 5, p. 538-546Research output: Contribution to journal › Article › peer-review
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Societal views on NICE, cancer drugs fund and value-based pricing criteria for prioritising medicines: a cross-sectional survey of 4118 adults in Great Britain
Hughes, D., Linley, W. G. & Hughes, D. A., 1 Aug 2013, In: Health Economics. 22, 8, p. 948-964Research output: Contribution to journal › Article › peer-review
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Statistical Methods for Adjusting Estimates of Treatment Effectiveness for Patient Non-adherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Systematic Review of Methodological Papers
Alshreef, A., Latimer, N., Tappenden, P., Wong, R., Hughes, D., Fotheringham, J. & Dixon, S., Nov 2019, In: Medical Decision Making. 39, 8, p. 910-925 16 p.Research output: Contribution to journal › Article › peer-review
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Statistical comments are unfounded.
Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Mar 2008, In: Value in Health. 11, 2, p. 346Research output: Contribution to journal › Article › peer-review
- Published
Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)
Balabanova, S., Taylor, C., Sills, G., Burnside, G., Plumpton, C., Smith, P., Appleton, R., Leach, J. P., Johnson, M., Baker, G. A., Pirmohamed, M., Hughes, D., Williamson, P., Tudor-Smith, C. & Marson, A. G., 26 Aug 2020, In: BMJ Open. 10, 8, e040635.Research output: Contribution to journal › Article › peer-review
- Published
Study protocol for a randomised controlled trial of insulin delivery by continuous subcutaneous infusion compared to multiple daily injections
Blair, J., Gregory, J., Hughes, D., Ridyard, C., Gamble, C., McKay, A., Didi, M., Thornborough, K., Bedson, E., Awoyale, L., Cwiklinski, E. & Peak, M., 16 Apr 2015, In: Trials. 16, 163.Research output: Contribution to journal › Article › peer-review
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Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica
Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Oct 2017, In: Health Technology Assessment. 21, 60, p. 1-180 180 p.Research output: Contribution to journal › Article › peer-review
- Published
Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial
Marsden, J., Kelleher, M., Gilvarry, E., Mitcheson, L., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hardy, W., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Vanderwaal, R., Wareham, A., Hughes, D. & Hoare, Z., Dec 2023, In: eClinicalMedicine. 66, 23 p., 102331.Research output: Contribution to journal › Article › peer-review
- Published
Supply-side cost-effectiveness thresholds: questions for evidence-based policy
Sampson, C., Zamora, B., Watson, S., Cairns, J., Chalkidou, K., Cubi-Molla, P., Devlin, N., García-Lorenzo, B., Hughes, D., Leech, A. & Towse, A., Sept 2022, In: Applied Health Economics and Health Policy. 20, 5, p. 651-667Research output: Contribution to journal › Article › peer-review
- Published
Supporting People With Type 2 Diabetes in the Effective Use of Their Medicine Through Mobile Health Technology Integrated With Clinical Care to Reduce Cardiovascular Risk: Protocol for an Effectiveness and Cost-effectiveness Randomized Controlled Trial
Farmer, A. J., Jones, L., Newhouse, N., Kenning, C., Williams, N., Chi, Y., Bartlett, K., Plumpton, C., McSharry, J., Cholerton, R., Holmes, E., Robinson, S., Allen, J., Gudgin, B., Velardo, C., Rutter, H., Horne, R., Tarassenko, L., Williams, V., Locock, L., Rea, R., Yu, L-M., Hughes, D., Bower, P. & French, D. P., 21 Feb 2022, In: JMIR Research Protocols. 11, 2, e32918.Research output: Contribution to journal › Article › peer-review
- Published
Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol
Farmer, A. J., Allen, J., Bartlett, K., Bower, P., Chi, Y., French, D. P., Gudgin, B., Holmes, E., Horne, R., Hughes, D., Kenning, C., Locock, L., McSharry, J., Miles, L., Newhouse, N., Rea, R., Riga, J., Tarassenko, L., Velardo, C., Williams, N., Williams, V. & Yu, L-M., 29 Dec 2019, In: BMJ Open. 9, 12, e033504.Research output: Contribution to journal › Article › peer-review
- E-pub ahead of print
Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial
SuMMiT-D Collaborative Group , 25 Jan 2024, (E-pub ahead of print) In: Pilot and Feasibility Studies. 10, 1, 15.Research output: Contribution to journal › Article › peer-review
- Published
Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation
Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. G. & Williamson, P., 1 May 2021, In: The Lancet Rheumatology. 3, 5, p. e347-e356Research output: Contribution to journal › Article › peer-review
- Published
Systematic Review: Outcomes and adverse events from randomised trials in Crohn's disease
Catt, H., Hughes, D., Kirkham, J. K. & Bodger, K., Apr 2019, In: Alimentary Pharmacology and Therapeutics. 49, 8, p. 978-996 19 p.Research output: Contribution to journal › Article › peer-review
- Published
Systematic review of follow-up of cancer in primary care verses secondary care: findings for breast and lung cancer
Hughes, D., Lewis, R., Neal, R. D., France, B., Williams, N. H., Wilkinson, C., Russell, I. T., Russell, D., Hughes, D. A., Stuart, N. S. & Weller, D., 1 Mar 2007.Research output: Contribution to conference › Paper
- Published
TEOS: A framework for constructing operational definitions of medication adherence based on Timelines – Events – Objectives – Sources
Dima, A. L., Allemann, S. S., Dunbar-Jacobs, J., Hughes, D., Vrijens, B. & Wilson, I., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2521-2533Research output: Contribution to journal › Article › peer-review
- Published
Taxonomy for methods of resource use measurement
DIRUM Team, 23 Jan 2015, In: Health Economics. 24, 3, p. 372-378Research output: Contribution to journal › Letter › peer-review
- Published
The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol
Hughes, D., Jenkinson, M. D., Gamble, C., Hartley, J. C., Hickey, H., Hughes, D. A., Blundell, M., Griffiths, M. J., Solomon, T. & Malluci, C. L., 3 Jan 2014, In: Trials. 15, 14Research output: Contribution to journal › Article › peer-review
- Published
The Development of a Consistent Europe-Wide Approach to Investigating the Economic Impact of Myalgic Encephalomyelitis (ME/CFS): A Report from the European Network on ME/CFS (EUROMENE)
Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 7 Apr 2020, In: Healthcare. 8, 2, 88.Research output: Contribution to journal › Article › peer-review
- Published
The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors
Hughes, D., Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Jan 2012, In: British Journal of Clinical Pharmacology. 73, 1, p. 66-76Research output: Contribution to journal › Article › peer-review
- Published
The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial
Jenkinson, M. D., Javadpour, M., Haylock, B. J., Young, B., Gillard, H., Vinten, J., Bulbeck, H., Das, K., Farrell, M., Looby, S., Hickey, H., Preusser, M., Mallucci, C. L., Hughes, D., Gamble, C. & Weber, D. C., 14 Nov 2015, In: Trials. 16Research output: Contribution to journal › Article › peer-review
- Published
The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1363-1374Research output: Contribution to journal › Article › peer-review
- Published
The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
Marson, A., Burnside, G., Appleton, R., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1375-1386Research output: Contribution to journal › Article › peer-review