North Wales Medical School

  1. Article › Research › Peer-reviewed
  2. Published

    A model-based cost-utility analysis of an automated notification system for deteriorating patients on general wards

    Holmes, E., Hughes, D. & Subbe, C., 2 May 2024, In: PLoS ONE. 19, 5, p. e0301643 e0301643.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    A proposal for using benefit-risk methods to improve the prominence of adverse event results when reporting trials

    Totton, N., Waddingham, E., Owen, R., Julious, S., Hughes, D. & Cook, J., 22 Jun 2024, In: Trials. 25, 409.

    Research output: Contribution to journalArticlepeer-review

  4. E-pub ahead of print

    A randomised controlled trial of a digital intervention (Renewed) to support symptom management, wellbeing and quality of life in cancer survivors

    Little, P., Bradbury, K., Stuart, B., Barnett, J., Krusche, A., Steele, M., Heber, E., Easton, S., Smith, K. A., Slodowska-Barabasz, J., Payne, L., Corbett, T., Wilde, L., Yao, G. L., Pollet , S., Smith, J., Joseph, J., Lawrence, M., Böhning, D., Cheetham-Blake, T., Eccles, D., Foster, C., Geraghty, A. W. A., Leydon, G., Müller, A. M., Neal, R. D., Osborne, R., Rathod, S., Richardson, A., Grimmett, C., Sharman, G., Bacon, R., Turner, L., Stephens, R., Rogers, K., Raftery, J., Zhu , S., Singh, K., Webley, F., Griffiths, G., Nutall, J., Chalder, T., Wilkinson, C., Watson, E. & Yardley, L., 20 Dec 2023, (E-pub ahead of print) In: British Journal of General Practice.

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Appropriate design and reporting of superiority, equivalence and non-inferiority clinical trials incorporating a benefit risk assessment: the BRAINS study including expert workshop

    Totton, N., Julious, S., Coates, E., Hughes, D., Cook, J., Biggs, K., Hewitt, C., Day, S. & Cooke, A., Oct 2023, In: Health Technology Assessment. 27, 20, 86 p.

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Better Living with Non‑memory‑led Dementia: protocol for a feasibility randomised controlled trial of a web‑based caregiver educational programme

    Suárez‑González, A., John, A., Brotherhood, E., Camic, P., McKee‐Jackson, R., Melville , M., Sullivan, M. P., Edwards, R. T., Windle, G., Crutch, S., Hoare, Z. & Stott, J., 11 Oct 2023, In: Pilot and Feasibility Studies. 9, 1, 13 p., 172.

    Research output: Contribution to journalArticlepeer-review

  7. Published

    CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence

    Crozier, L., Foy, R., adib, R., Kar, A., Holt, J., Pareri, A., Valverde, J., Riviera, R., Weston, W., Wilson, R., Regnault, C., Whitfield, P., Badonyi, M., Bennett, L., Vernon, E., Gamble, A., Marsh, J., Staples, C., Saurin, A., Barr, A. & Ly, T., 16 Nov 2023, In: Molecular Cell. 83, 22, p. 4062-4077 15 p.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Detection of endometrial cancer in cervico-vaginal fluid and blood plasma: Leveraging proteomics and machine learning for biomarker discover

    Njoku, K., Pierce, A., Chiasserini, D., Geary, B., Campbell, A. E., Kelsall, J., Reed, R., Geifman, N., Whetton, A. D. & Crosbie, E. J., Apr 2024, In: eBioMedicine. 102, p. 105064

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Developing an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project

    Holmes, E., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Foster, D., Hardman, K., Bell, S., Marson, A., Hughes, D. & Noble, A. J., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 28-37 10 p.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Digital Remote Monitoring Using an mHealth Solution for Survivors of Cancer: Protocol for a Pilot Observational Study

    Innominato, P. F., Macdonald, J., Saxton, W., Longshaw, L., Granger, R., Naja, I., Allocca, C., Edwards, R., Rasheed, S., Folkvord, F., de Battle, J., Ail, R., Motta, E., Bale, C., Fuller, C., Mullard, A. P., Subbe, C., Griffiths, D., Wreglesworth, N., Pecchia, L., Fico, G. & Antonini, A., 30 Apr 2024, In: JMIR Research Protocols. 13, p. e52957 e52957.

    Research output: Contribution to journalArticlepeer-review

  11. Published

    Effects of Home-Based EEG Neurofeedback Training as a Non-Pharmacological Intervention for Parkinson’s Disease

    Cooke, A., Hindle, J., Lawrence, C., Bellomo, E., Pritchard, A. W., MacLeod, C., Martin-Forbes, P., Jones, S., Bracewell, M., Linden, D. & Mehler, D., Sept 2024, In: Neurophysiologie Clinique/Clinical Neurophysiology. 54, 5, 102997.

    Research output: Contribution to journalArticlepeer-review

  12. E-pub ahead of print

    Evidence following conditional NICE technology appraisal recommendations: A critical analysis of methods, quality and risk of bias

    Pijeira Perez, Y. & Hughes, D., 9 Sept 2024, (E-pub ahead of print) In: Pharmacoeconomics.

    Research output: Contribution to journalArticlepeer-review

  13. Published

    Expert Insight Into the Use of eHealth Interventions to Aid Medication Adherence During COVID-19

    Hassan, A. & Davies, N., 21 Mar 2024, In: Patient Preference and Adherence. 18, p. 721-731 11 p.

    Research output: Contribution to journalArticlepeer-review

  14. Published

    Hard to Reach and Hidden: Improving the Identification of Young Dementia Carers

    Masterson Algar, P., Egan, K., Flynn, G., Hughes, G., Spector, A., Stott, J. & Windle, G., 23 Nov 2023, In: International Journal of Environmental Research and Public Health. 20, 23, 15 p., 7103.

    Research output: Contribution to journalArticlepeer-review

  15. Published

    Hidden systems in primary care cancer detection: an embedded qualitative intervention development study

    Hiscock, J., Law, R.-J., Brain, K., Smidts, S., Nafees, S., Williams, N., Rose , J., Lewis, R., Roberts, J., Hendry, A., Neal, R. & Wilkinson, C., Aug 2024, In: British Journal of General Practice. 74, 745, p. e544-e551

    Research output: Contribution to journalArticlepeer-review

  16. Published

    Implementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya-individually randomised superiority trial

    Fonagy, P., Chammay, R. E., Ngunu, C., Kumar, M., Verdeli, L., Allison, E., Anani, G., Fearon, P., Fouad, F., Hoare, Z., Koyio, L., Moore, H., Nyandigisi, A., Pilling, S., Sender, H., Skordis, J., Evans, R., Jaoude, G. J. A., Madeghe, B., Maradian, S. P. A., O'Donnell, C., Simes, E., Truscott, A., Wambua, G. N. & Yator, O., 26 Mar 2024, In: Trials. 25, 1, 217.

    Research output: Contribution to journalArticlepeer-review

  17. Published

    Informing evidence-based policy during the COVID-19 pandemic and recovery period: learning from a national evidence centre

    Cooper, A., Lewis, R., Gal, M., Joseph-Williams, N., Greenwell, J., Watkins, A., Strong, A., Williams, D., Doe, E., Law, R.-J. & Edwards, A., 31 May 2024, In: Global Health Research and Policy. 9, 1, p. 18 18.

    Research output: Contribution to journalArticlepeer-review

  18. Published

    Interventions to mitigate the risks of COVID-19 for people experiencing homelessness and their effectiveness: a systematic review

    Ogbonna, O., Bull, F., Spinks, B., Williams, D., Lewis, R. & Edwards, A., 4 Jan 2024, In: Frontiers in Public Health. 11, 1286730.

    Research output: Contribution to journalArticlepeer-review

  19. Published

    Methodological approaches to measuring mental health in a cost-of-living crisis: A rapid review

    England, C., Jarrom, D., Washington, J., Hasler, E., Batten, L., Edwards, A. & Lewis, R., Jun 2024, In: Health Policy. 144, 105062.

    Research output: Contribution to journalArticlepeer-review

  20. Published

    Mitigating COVID-19 Burden in People Experiencing Incarceration: A Systematic Review

    Spinks, B., Williams, D., Williams, D., Lewis, R., Bull, F., Ogbonna, O. & Edwards, A., 1 Jun 2024, In: Journal of Correctional Health Care. 30, 3, p. 172-197 26 p.

    Research output: Contribution to journalArticlepeer-review

  21. Published

    Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study

    Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L., Jul 2024, In: ACR Open Rheumatology. 6, 7, p. 403-411 9 p.

    Research output: Contribution to journalArticlepeer-review

  22. Published

    Physical Activity Mobile App (CareFit) for Informal Carers of People With Dementia: Protocol for a Feasibility and Adaptation Study

    Egan, K., MacDonald, B., Hodgson, W., Kirk, A., Fawcett, B., Dunlop, M., Flynn, G., Stott, J. & Windle, G., 12 Sept 2024, In: Journal of Medical Internet Research. 13, 9 p., e53727.

    Research output: Contribution to journalArticlepeer-review

  23. Published

    Potential types of bias when estimating causal effects in environmental research and how to interpret them

    Konno, K., Gibbons, J., Lewis, R. & Pullin, A., 7 Feb 2024, In: Environmental Evidence. 13, 1, 1.

    Research output: Contribution to journalArticlepeer-review

  24. Published

    Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project

    Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 17-27 11 p.

    Research output: Contribution to journalArticlepeer-review

  25. E-pub ahead of print

    Setting the context for a complex dental intervention of role substitution in care homes: Initial process evaluation findings

    Hendry, A., Baker, S., McKenna, G., Tsakos, G., Chestnutt, I., Smith, C., Jones, V., O'Neill, C., Jenkins, A., Evans, R., Syed, S. S., Mirza, A., Harvey, M., Karki, A., Moons, K., Sandom, F., Donaldson, M., Lappin, C., Shepherd, K. & Brocklehurst, P., 27 Mar 2024, (E-pub ahead of print) In: Gerodontology. p. 1-12

    Research output: Contribution to journalArticlepeer-review

  26. Published

    Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial

    Marsden, J., Kelleher, M., Gilvarry, E., Mitcheson, L., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hardy, W., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Vanderwaal, R., Wareham, A., Hughes, D. & Hoare, Z., Dec 2023, In: eClinicalMedicine. 66, 23 p., 102331.

    Research output: Contribution to journalArticlepeer-review

  27. E-pub ahead of print

    Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial

    SuMMiT-D Collaborative Group , 25 Jan 2024, (E-pub ahead of print) In: Pilot and Feasibility Studies. 10, 1, 15.

    Research output: Contribution to journalArticlepeer-review

  28. Published

    Switching antipsychotic medication to reduce sexual dysfunction in people with psychosis: the REMEDY RCT

    Crawford, M. J., Thana, L., Evans, R., Carne, A., O'Connell, L., Claringbold, A., Saravanamuthu, A., Case, R., Munjiza, J., Jayacodi, S., Reilly, J. G., Hughes, E., Hoare, Z., Barrett, B., Leeson, V. C., Paton, C., Keown, P., Pappa, S., Green, C. & Barnes, T. R., 1 Sept 2020, In: Health Technology Assessment. 24, 44, 54 p.

    Research output: Contribution to journalArticlepeer-review

  29. Published

    The Effects of the COVID-19 Pandemic on People Experiencing Incarceration: a Systematic Review

    Williams, D. B., Spinks, B., Williams, D., Lewis, R., Bull, F. & Edwards, A., 5 Apr 2024, In: BMJ Open. 14, 17 p., e076451.

    Research output: Contribution to journalArticlepeer-review

  30. Published

    The experiences and perspectives of people with gout on urate self-monitoring

    Michael, T. J. F., Chan, J. S., Hughes, S., Wright, D. F. B., Coleshill, M. J., Hughes, D., Day, R. O., Aslani, P. & Stocker, S. L., Jun 2024, In: Health Expectations. 27, 3, 9 p., e14071.

    Research output: Contribution to journalArticlepeer-review

  31. Published

    The impact of parent treatment preference and other factors on recruitment: lessons learned from a paediatric epilepsy randomised controlled trial

    Carter, B., Bray, L., Al-Najjar, N., Tort Piella, A., Smith, C. T., Spowart, C., Collingwood, A., Crudgington, H., Currier, J., Hughes, D., Wood, E., Martin, R., Morris, C., Roberts, D., Rouncefield-Swales , A., Sutherland, H., Watson, V., Cook, G., Wiggs, L., Gringas, P. & Pal, D., 6 Feb 2023, In: Trials. 24, 1, 83.

    Research output: Contribution to journalArticlepeer-review

  32. Published

    Understanding quantitative research: part 2

    Hoare, Z. & Hoe, J., 26 Feb 2013, In: Nursing Standard. 27, 18, p. 48-55; quiz 57

    Research output: Contribution to journalArticlepeer-review

  33. Published

    We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment

    Charlton, V., diStefano, M., Mitchell, P., Morrell, L., Rand, L., Badano, G., Baker, R., Calnan, M., Chalkidou, K., Culyer, A., Howden, D., Hughes, D., Lomas, J., Max, C., McCabe, C., O'Mahony, J. F., Paulden, M., Pemberton-Whiteley, Z., Rid, A., Scuffham, P., Sculpher, M., Shah, K., Weale, A. & Wester, G., Apr 2024, In: Health Economics, Policy and Law. 19, 2, p. 153-173

    Research output: Contribution to journalArticlepeer-review

  34. E-pub ahead of print

    ‘ThinkCancer!’ – Randomised feasibility trial of a novel practice-based early cancer diagnosis intervention

    Disbeschl, S., Hendry, A., Surgey, A., Walker, D., Goulden, N., Anthony, B., Neal, R., Williams, N., Hoare, Z., Hiscock, J., Edwards, R. T., Lewis, R. & Wilkinson, C., 3 May 2024, (E-pub ahead of print) In: BJGP open.

    Research output: Contribution to journalArticlepeer-review

  35. Other contribution › Research › Not peer-reviewed
  36. Published

    CARiAD: Training healthcare professionals to train lay carers

    Poolman, M., 25 Sept 2023

    Research output: Other contribution

  37. Unpublished

    Implementation framework for carer-administration (utilising QIF)

    Poolman, M., 2022, (Unpublished)

    Research output: Other contribution

  38. Other report › Research › Not peer-reviewed
  39. Published
  40. Published
  41. Published
  42. Review article › Research › Peer-reviewed
  43. Published

    The Effectiveness and Cost-Effectiveness of Community Diagnostic Centres: A Rapid Review

    Wale, A., Okolie, C., Everitt, J., Hookway, A., Shaw, H., Little, K., Lewis, R., Cooper, A. & Edwards, A., 23 Jan 2024, In: International Journal of Public Health . 69, 1606243.

    Research output: Contribution to journalReview articlepeer-review

  44. Conference article › Research › Peer-reviewed
  45. Published

    Economic analysis of treatments for children who do not achieve adequate asthma control when using low-dose inhaled corticosteroids

    Culeddu, G., Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Turner, S., Smith, C. T. & Hughes, D., 30 Jul 2024, In: Disease in Childhood. 109, suppl 1

    Research output: Contribution to journalConference articlepeer-review

  46. Preprint › Research
  47. Published

    A bespoke rapid evidence review process engaging stakeholders for supporting evolving and time-sensitive policy and clinical decision-making: reflection and lessons learned from the Wales Covid-19 Evidence Centre 2021-23

    Lewis, R., Cooper, A., Jarrom, D., Mann, M., Law, R.-J., Edwards, D., Carrier, J., Shaw, H., Winfield, T., Spencer, L., Noyes, J., Morgan, H., Washington, J., Hasler, E., Gal, M., Doe, E., Joseph-Williams, N. & Edwards, A., 23 Jan 2024, Research Square.

    Research output: Working paperPreprint

  48. Published

    A rapid review exploring the effectiveness of artificial intelligence for cancer diagnosis

    Wale, A., Shaw, H., Ayres, T., Okolie, C., Edwards, R. T., Davies, J., Lewis, R., Cooper, A. & Edwards, A., 9 Nov 2023, MedRxiv.

    Research output: Working paperPreprint

  49. Published

    Prognostic factors for a change in eye health or vision: A rapid review

    Hammond, G., Needham-Taylor, A., Bromham, N., Gillen, E., Searchfield, L., Lewis, R., Cooper, A., Edwards, A., Edwards, R. T. & Davies, J., 18 Jan 2024, MedRxiv.

    Research output: Working paperPreprint

  50. Published

    The clinical and cost-effectiveness of interventions for preventing continence issues resulting from birth trauma: a rapid review

    Anthony, B., Davies, J., Pisavadia, K., Roberts, S., Spencer, L. H., Gillen, E., Hounsome, J., Noyes, J., Hughes, D., Fitzsimmons, D., Edwards, R. T., Edwards, A., Cooper, A. & Lewis, R., 9 Sept 2024, MedRxiv.

    Research output: Working paperPreprint

  51. Published

    The costs and cost-effectiveness of different service models of palliatice care, focusing on end of life care: A rapid review

    Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Gillen, E., Noyes, J., Fitzsimmons, D., Lewis, R., Cooper, A., Hughes, D., Edwards, R. T. & Edwards, A., 7 Mar 2024, MedRxiv, 118 p.

    Research output: Working paperPreprint

  52. Published

    Wellness in work - supporting people in work and assisting people to return to the workforce: An economic evidence review.

    Edwards, R. T., Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Makanjuola, A., Lloyd-Williams, H., Fitzsimmons, D., Collins, B., Charles, J., Lewis, R., Cooper, A., Barutcu, S. & McKibben, M.-A., 17 Jan 2024, MedRxiv.

    Research output: Working paperPreprint

  53. Published

    What are the most effective interventions to support children and young people bereaved by suicide in the family: a rapid review

    Mann, M., Kisleva, M., Searchfield, L., Mazzaschi, F., Jones, R., Lifford, K., Weightman, A., John, A., Lewis, R., Edwards, R. T., Davies, J., Cooper, A. & Edwards, A., 25 Sept 2023, MedRxiv.

    Research output: Working paperPreprint