Changing Agendas on Sleep, Treatment and Learning in Epilepsy (CASTLE) Sleep-E: A protocol for a randomised controlled trial comparing an online behavioural sleep intervention with standard care in children with Rolandic epilepsy

Al-Najjar, N., Bray, L., Carter, B., Collingwood, A., Cook, G., Crudgington, H., Dietz, K., Hardy, W., Hiscock, H., Hughes, D., Morris, C., Rouncefield-Swales , A., Saron, H., Spowart, C., Stibbs-Easton, L., Tudur Smith, C., Watson, V., Whittle, L., Wiggs, L., Wood, E., Gringas, P. & Pal, D. K., 10 Mar 2023, In: BMJ Open. 13, 3, e065769.

Research output: Contribution to journal › Article › peer-review

Impact on the phased abolition of co-payments on the utilisation of selected prescription medicines in Wales

Alam, M. F., Cohen, D., Dunstan, F., Hughes, D. & Routledge, P. A., Jan 2018, In: Health Economics. 27, 1, p. 236-243

Research output: Contribution to journal › Article › peer-review

What should patients do if they miss a dose? A systematic review of patient information leaflets and summaries of product characteristics

Albassam, A. & Hughes, D., Feb 2021, In: European Journal of Clinical Pharmacology. 77, 2, p. 251-260 10 p.

Research output: Contribution to journal › Article › peer-review

Statistical Methods for Adjusting Estimates of Treatment Effectiveness for Patient Non-adherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Systematic Review of Methodological Papers

Alshreef, A., Latimer, N., Tappenden, P., Wong, R., Hughes, D., Fotheringham, J. & Dixon, S., Nov 2019, In: Medical Decision Making. 39, 8, p. 910-925 16 p.

Research output: Contribution to journal › Article › peer-review

Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)

Balabanova, S., Taylor, C., Sills, G., Burnside, G., Plumpton, C., Smith, P., Appleton, R., Leach, J. P., Johnson, M., Baker, G. A., Pirmohamed, M., Hughes, D., Williamson, P., Tudor-Smith, C. & Marson, A. G., 26 Aug 2020, In: BMJ Open. 10, 8, e040635.

Research output: Contribution to journal › Article › peer-review

Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation

Bedson, E., Bell, D., Carr, D., Carter, B., Hughes, D., Jorgensen, A., Lewis, H., Lloyd, K., McCaddon, A., Moat, S., Pink, J., Pirmohamed, M., Roberts, S., Russell, I., Sylvestre, Y., Tranter, R., Whitaker, R., Wilkinson, C. & Williams, N., Jul 2014, In: Health Technology Assessment. 18, 48, p. 1-159

Research output: Contribution to journal › Article › peer-review

Study protocol for a randomised controlled trial of insulin delivery by continuous subcutaneous infusion compared to multiple daily injections

Blair, J., Gregory, J., Hughes, D., Ridyard, C., Gamble, C., McKay, A., Didi, M., Thornborough, K., Bedson, E., Awoyale, L., Cwiklinski, E. & Peak, M., 16 Apr 2015, In: Trials. 16, 163.

Research output: Contribution to journal › Article › peer-review

Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT

Blair, J., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. & Gamble, C., Aug 2018, In: Health Technology Assessment. 22, 42, p. 1-112 112 p.

Research output: Contribution to journal › Article › peer-review

Continuous subcutaneous insulin infusion versus multiple daily injection regimens in children and young people at diagnosis of type 1 diabetes: pragmatic randomised controlled trial and economic evaluation

Blair, J. C., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. A. & Gamble, C., 3 Apr 2019, In: British Medical Journal. 365, p. l1226 l1226.

Research output: Contribution to journal › Article › peer-review

Societal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods

Bourke, S. M., Plumpton, C. & Hughes, D., 9 May 2018, In: Value in Health. 21, 5, p. 538-546

Research output: Contribution to journal › Article › peer-review

2016 Prof. John Urquhart Obituary

Breckenridge, A. & Hughes, D., Aug 2016, In: British Journal of Clinical Pharmacology. 82, 2, p. 573

Research output: Contribution to journal › Letter › peer-review

Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial

Brogan, P. A., Arch, B., Hickey, H., Anton, J., Iglesias, E., Baildam, E., Mahmood, K., Cleary, G., Moraitis, E., Papadopoulou, C., Beresford, M. W., Riley, P., Demir, S., Ozen, S., Culeddu, G., Hughes, D., Dolezalova, P., Hampson, L., Whitehead, J., Jayne, D., Ruperto, N., Tudor-Smith, C. & Eleftheriou, D., Sept 2021, In: Arthritis and Rheumatology. 73, 9, p. 1673-1682

Research output: Contribution to journal › Article › peer-review

Parenting programme for parents of children at risk of developing conduct disorder: cost effectiveness analysis.

Bywater, T. J., Hutchings, J. M., Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 31 Mar 2007, In: British Medical Journal. 334, 7595, p. 682-685

Research output: Contribution to journal › Article › peer-review

Plasma Methylmalonic Acid Concentration in Folic Acid–Supplemented Depressed Patients with Low or Marginal Vitamin B-12: A Randomized Trial

Carter, B., Zenasni, Z., Moat, S. J., Hudson, P. R., Russell, I. T., McCaddon, A., Whitaker, R., Pink, J., Roberts, S., Wilkinson, C., Hughes, D., Betson, E., Carr, D., Jorgenson, A., Pirmohamed, M., Williams, N., Lewis, H., Lloyd, K., Sylvesture, Y. & Tranter, R., Dec 2021, In: Journal of Nutrition. 151, 12, p. 3738-3745 8 p.

Research output: Contribution to journal › Article › peer-review

The impact of parent treatment preference and other factors on recruitment: lessons learned from a paediatric epilepsy randomised controlled trial

Carter, B., Bray, L., Al-Najjar, N., Tort Piella, A., Smith, C. T., Spowart, C., Collingwood, A., Crudgington, H., Currier, J., Hughes, D., Wood, E., Martin, R., Morris, C., Roberts, D., Rouncefield-Swales , A., Sutherland, H., Watson, V., Cook, G., Wiggs, L., Gringas, P. & Pal, D., 6 Feb 2023, In: Trials. 24, 1, 83.

Research output: Contribution to journal › Article › peer-review

Value assessment and quantitative benefit-risk modelling of biosimilar infliximab for Crohn’s disease

Catt, H., Bodger, K., Hughes, D. & Kirkham, J. J., Dec 2019, In: PharmacoEconomics. 37, 12, p. 1509-1523 15 p.

Research output: Contribution to journal › Article › peer-review

Systematic Review: Outcomes and adverse events from randomised trials in Crohn's disease

Catt, H., Hughes, D., Kirkham, J. K. & Bodger, K., Apr 2019, In: Alimentary Pharmacology and Therapeutics. 49, 8, p. 978-996 19 p.

Research output: Contribution to journal › Article › peer-review

Managing Access to Advanced Therapy Medicinal Products: Challenges for NHS Wales

Champion, A. R., Lewis, S., Davies, S. & Hughes, D., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2444-2449

Research output: Contribution to journal › Article › peer-review

We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment

Charlton, V., diStefano, M., Mitchell, P., Morrell, L., Rand, L., Badano, G., Baker, R., Calnan, M., Chalkidou, K., Culyer, A., Howden, D., Hughes, D., Lomas, J., Max, C., McCabe, C., O'Mahony, J. F., Paulden, M., Pemberton-Whiteley, Z., Rid, A., Scuffham, P., Sculpher, M., Shah, K., Weale, A. & Wester, G., Apr 2024, In: Health Economics, Policy and Law. 19, 2, p. 153-173

Research output: Contribution to journal › Article › peer-review

Community views on factors affecting medicines resource allocation: Cross-sectional survey of 3080 adults in Australia

Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 2019, In: Australian Health Review . 43, 3, p. 254-260

Research output: Contribution to journal › Article › peer-review

Societal perspective on access to publicly subsidised medicines: A cross sectional survey of 3080 adults in Australia

Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 1 Mar 2017, In: PLoS ONE.

Research output: Contribution to journal › Article › peer-review

EstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): Protocol for a systematic review, network meta-analysis and cost-effectiveness analysis using individual participant data (IPD)

Cividini, S., Sinha, I., Donegan, S., Maden, M., Culeddu, G., Rose, K., Fulton, O., Hughes, D., Turner, S. & Smith, C. T., 5 Feb 2021, In: BMJ Open. 11, e040528.

Research output: Contribution to journal › Article › peer-review

Best step-up treatments for children with uncontrolled asthma: A systematic review and network meta-analysis of individual participant data

Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Culeddu, G., Hughes, D., Turner, S. & Tudor-Smith, C., 21 Dec 2023, In: European Respiratory Journal. 62, 6, 2301011.

Research output: Contribution to journal › Article › peer-review

Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus

Crudgington, H., Rogers, M., Bray, L., Carter, B., Currier, J., Gibbon, F., Hughes, D., Lyle, S., Roberts, D., Smith, C. T., Gringras, P., Pal, D. & Morris, C., May 2019, In: Epilepsia. 60, 5, p. 857-871

Research output: Contribution to journal › Article › peer-review

Cost effectiveness analysis of treatments for children with uncontrolled asthma symptoms despite taking inhaled corticosteroids

Culeddu, G., Sinha, I., Donegan, S., Maden, M., Cividini, S., Rose, K., Fulton, O., Turner, S., Tudor-Smith, C. & Hughes, D., 27 Oct 2023, In: European Respiratory Journal. 62 , Supplement 67, PA 523.

Research output: Contribution to journal › Meeting Abstract › peer-review

Novel oral iron therapy for iron deficiency anaemia: How to value safety in a new drug?

Culeddu, G., Su, L., Chen, Y., Pereira, D. I. A., Powell, J. J. & Hughes, D., Mar 2022, In: British Journal of Clinical Pharmacology. 88, 3, p. 1347-1357 11 p.

Research output: Contribution to journal › Article › peer-review

Economic analysis of treatments for children who do not achieve adequate asthma control when using low-dose inhaled corticosteroids

Culeddu, G., Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Turner, S., Smith, C. T. & Hughes, D., 30 Jul 2024, In: Disease in Childhood. 109, suppl 1

Research output: Contribution to journal › Conference article › peer-review

Perceptions of European ME/CFS experts concerning knowledge and understanding of ME/CFS among primary care physicians in Europe: A report from the European ME/CFS Research Network (EUROMENE)

Cullinan, J., Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., de Korwin, J.-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 26 Feb 2021, In: Medicina. 57, 3, 208.

Research output: Contribution to journal › Article › peer-review

Affordable orphan drugs: A role for not-for-profit organisations

Davies, E. H., Fulton, E., Brook, D. & Hughes, D., Jul 2017, In: British Journal of Clinical Pharmacology. 83, 7, p. 1595-1601

Research output: Contribution to journal › Article › peer-review

ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

De Geest, S., Zullig, L. L., Dunbar-Jacob, J., Helmy, R., Hughes, D., Wilson, I. & Vrijens, B., 3 Jul 2018, In: Annals of Internal Medicine. 169, 1, p. 30-35

Research output: Contribution to journal › Article › peer-review

Methodological considerations on estimating medication adherence from self-report, electronic monitoring, and electronic healthcare databases using the TEOS framework

Dima, A. L., Allemann, S. S., Dunbar-Jacob, J., Hughes, D., Vrijens, B. & Wilson, I., Jul 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 1918-1927

Research output: Contribution to journal › Article › peer-review

TEOS: A framework for constructing operational definitions of medication adherence based on Timelines – Events – Objectives – Sources

Dima, A. L., Allemann, S. S., Dunbar-Jacobs, J., Hughes, D., Vrijens, B. & Wilson, I., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2521-2533

Research output: Contribution to journal › Article › peer-review

Involving colleagues can be challenging

Fargher , E. & Hughes, D., 2 Apr 2011, In: Pharmaceutical Journal. 286, p. 404

Research output: Contribution to journal › Letter › peer-review

Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol

Farmer, A. J., Allen, J., Bartlett, K., Bower, P., Chi, Y., French, D. P., Gudgin, B., Holmes, E., Horne, R., Hughes, D., Kenning, C., Locock, L., McSharry, J., Miles, L., Newhouse, N., Rea, R., Riga, J., Tarassenko, L., Velardo, C., Williams, N., Williams, V. & Yu, L.-M., 29 Dec 2019, In: BMJ Open. 9, 12, e033504.

Research output: Contribution to journal › Article › peer-review

Supporting People With Type 2 Diabetes in the Effective Use of Their Medicine Through Mobile Health Technology Integrated With Clinical Care to Reduce Cardiovascular Risk: Protocol for an Effectiveness and Cost-effectiveness Randomized Controlled Trial

Farmer, A. J., Jones, L., Newhouse, N., Kenning, C., Williams, N., Chi, Y., Bartlett, K., Plumpton, C., McSharry, J., Cholerton, R., Holmes, E., Robinson, S., Allen, J., Gudgin, B., Velardo, C., Rutter, H., Horne, R., Tarassenko, L., Williams, V., Locock, L., Rea, R., Yu, L.-M., Hughes, D., Bower, P. & French, D. P., 21 Feb 2022, In: JMIR Research Protocols. 11, 2, e32918.

Research output: Contribution to journal › Article › peer-review

Health utilities and quality-adjusted life years for patients with amyotrophic lateral sclerosis receiving reldesemtiv or placebo in FORTITUDE-ALS

Gebrehiwet, P., Meng, L., Saroccoa, P., Wei, J., Wolff, A. A., Butzner, M., Chio, A., Andrews, J. A., Genge, A., Hughes, D., Jackson, C. E., Lechtzin, N., Miller, T. M. & Shefner, J. M., 31 Mar 2023, In: Journal of Medical Economics. 26, 1, p. 488-493 6 p.

Research output: Contribution to journal › Article › peer-review

Impregnated central venous catheters for prevention of bloodstream infection in children (the CATCH trial): a randomised controlled trial

Gilbert, R. E., Mok, Q., Dwan, K., Harron, K., Moitt, T., Millar, M., Ramnarayan, P., Tibby, S. M., Hughes, D. & Gamble, C. F., 23 Apr 2016, In: The Lancet. 387, 10029, p. 1732-1742

Research output: Contribution to journal › Article › peer-review

Psychometric properties of an adapted stigma scale and experiences of stigma associated with HIV pre-exposure prophylaxis use among men who have sex with men: a mixed methods study

Gillespie, D. & Hughes, D., Jul 2023, In: AIDS and Behavior. 27, 7, p. 2397-2410 14 p.

Research output: Contribution to journal › Article › peer-review

PrEP use, sexual behaviour, and PrEP adherence among men who have sex with men living in Wales prior to and during the COVID-19 pandemic

Gillespie, D., Couzens, Z., de Bruin, M., Hughes, D., Jones, A., Ma, R., Williams, A., Wood, F. & Blee, K., Aug 2022, In: AIDS and Behavior. 26, 8, p. 2746-2757 12 p.

Research output: Contribution to journal › Article › peer-review

Experiences of men who have sex with men when initiating, implementing, and persisting with HIV pre-exposure prophylaxis

Gillespie, D., Wood, F., Williams, A., Ma, R., de Bruin, M., Hughes, D., Jones, A. T., Couzens, Z. & Hood, K., Aug 2022, In: Health Expectations. 25, 4, p. 1332-1341 10 p.

Research output: Contribution to journal › Article › peer-review

Between- and within-individual sociodemographic and psychological determinants of PrEP adherence among men who have sex with men prescribed a daily PrEP regimen in Wales

Gillespie, D., de Bruin, M., Hughes, D., Ma, R., Williams, A., Wood, F., Couzens, Z., Jones, A. T. & Hood, K., May 2023, In: AIDS and Behavior. 27, 5, p. 1564-1572 9 p.

Research output: Contribution to journal › Article › peer-review

Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales

Gillespie, D., Knapper, C., Hughes, D., Couzen, Z., Wood, F., de Bruin, M., Ma, R., Jones, A. T., Williams, A. & Hood, K., 17 Feb 2021, In: Sexually transmitted infections. 97, 2, p. 85-87 3 p., 054598.

Research output: Contribution to journal › Article › peer-review

Renal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment

Hagemi, A., Plumpton, C. & Hughes, D., 2 Oct 2017, In: BMC Nephrology. 18, 305.

Research output: Contribution to journal › Article › peer-review

Methods for Extrapolating Survival Analyses for the Economic Evaluation of Advanced Therapy Medicinal Products

Hardy, W. & Hughes, D., 16 Sept 2022, In: Human Gene Therapy. 33, 17-18, p. 845-856

Research output: Contribution to journal › Article › peer-review

CATheter Infections in CHildren (CATCH): a randomised controlled trial and economic evaluation comparing impregnated and standard central venous catheters in children

Harron, K., Mok, Q., Dwan, K., Ridyard, C., Mott, T., Millar, M., Ramnarayan, P., Tibby, S. M., Muller-Pebody, B., Hughes, D., Gamble, C. & Gilbert, R. E., Mar 2016, In: Health Technology Assessment. 20, 18

Research output: Contribution to journal › Article › peer-review