Research Portal

North Wales Medical School

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  1. Published

    The clinical and cost-effectiveness of interventions for preventing continence issues resulting from birth trauma: a rapid review

    Anthony, B., Davies, J., Pisavadia, K., Roberts, S., Spencer, L. H., Gillen, E., Hounsome, J., Noyes, J., Hughes, D., Fitzsimmons, D., Edwards, R. T., Edwards, A., Cooper, A. & Lewis, R., 9 Sept 2024, MedRxiv.

    Research output: Working paper › Preprint

  2. Published

    What is the most effective method of delivering Making Every Contact Count training? A rapid review

    Batten, L., Hammond, G., England, C., Jarrom, D., Gillen, E., Davies, J., Edwards, R. T., Edwards, A., Cooper, A. & Lewis, R., 21 Oct 2024, Health and Care Research Wales. 55 p.

    Research output: Book/Report › Other report › peer-review

  3. Published

    A Theoretically Informed Process Evaluation in Parallel to a Feasibility Study of a Complex Oral Health Intervention Using NICE Guidelines in a Care Home Setting

    Brocklehurst, P., Langley, J., Wassell, R., Daniyal, S., Syed, S. S., Harvey, M., Goulden, N., Sherriff, A., Heilmann, A., Hoare, Z., Smith, C., Watt, R., O'Neill, C., Kee, F., Cairns, P., Lievesley, N., McKenna, G. & Tsakos, G., 15 Jan 2025, In: Community Dentistry and Oral Epidemiology. 53, 2, p. 152-159

    Research output: Contribution to journal › Article › peer-review

  4. Published

    Exploring psychosocial factors in the development pathways of elite UK triathletes: A Multi-study approach

    Brooks, H., Thomas, O., Evans, L., Barlow, M., Lane, A. & Hardy, W., 30 Nov 2022.

    Research output: Contribution to conference › Poster

  5. Published

    The impact of parent treatment preference and other factors on recruitment: lessons learned from a paediatric epilepsy randomised controlled trial

    Carter, B., Bray, L., Al-Najjar, N., Tort Piella, A., Smith, C. T., Spowart, C., Collingwood, A., Crudgington, H., Currier, J., Hughes, D., Wood, E., Martin, R., Morris, C., Roberts, D., Rouncefield-Swales , A., Sutherland, H., Watson, V., Cook, G., Wiggs, L., Gringas, P. & Pal, D., 6 Feb 2023, In: Trials. 24, 1, 83.

    Research output: Contribution to journal › Article › peer-review

  6. Published

    We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment

    Charlton, V., diStefano, M., Mitchell, P., Morrell, L., Rand, L., Badano, G., Baker, R., Calnan, M., Chalkidou, K., Culyer, A., Howden, D., Hughes, D., Lomas, J., Max, C., McCabe, C., O'Mahony, J. F., Paulden, M., Pemberton-Whiteley, Z., Rid, A., Scuffham, P., Sculpher, M., Shah, K., Weale, A. & Wester, G., Apr 2024, In: Health Economics, Policy and Law. 19, 2, p. 153-173

    Research output: Contribution to journal › Article › peer-review

  7. Published

    Effects of Home-Based EEG Neurofeedback Training as a Non-Pharmacological Intervention for Parkinson’s Disease

    Cooke, A., Hindle, J., Lawrence, C., Bellomo, E., Pritchard, A. W., MacLeod, C., Martin-Forbes, P., Jones, S., Bracewell, M., Linden, D. & Mehler, D., Sept 2024, In: Neurophysiologie Clinique/Clinical Neurophysiology. 54, 5, 102997.

    Research output: Contribution to journal › Article › peer-review

  8. Published

    Informing evidence-based policy during the COVID-19 pandemic and recovery period: learning from a national evidence centre

    Cooper, A., Lewis, R., Gal, M., Joseph-Williams, N., Greenwell, J., Watkins, A., Strong, A., Williams, D., Doe, E., Law, R.-J. & Edwards, A., 31 May 2024, In: Global Health Research and Policy. 9, 1, p. 18 18.

    Research output: Contribution to journal › Article › peer-review

  9. Published

    Switching antipsychotic medication to reduce sexual dysfunction in people with psychosis: the REMEDY RCT

    Crawford, M. J., Thana, L., Evans, R., Carne, A., O'Connell, L., Claringbold, A., Saravanamuthu, A., Case, R., Munjiza, J., Jayacodi, S., Reilly, J. G., Hughes, E., Hoare, Z., Barrett, B., Leeson, V. C., Paton, C., Keown, P., Pappa, S., Green, C. & Barnes, T. R., 1 Sept 2020, In: Health Technology Assessment. 24, 44, 54 p.

    Research output: Contribution to journal › Article › peer-review

  10. Published

    CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence

    Crozier, L., Foy, R., adib, R., Kar, A., Holt, J., Pareri, A., Valverde, J., Riviera, R., Weston, W., Wilson, R., Regnault, C., Whitfield, P., Badonyi, M., Bennett, L., Vernon, E., Gamble, A., Marsh, J., Staples, C., Saurin, A., Barr, A. & Ly, T., 16 Nov 2023, In: Molecular Cell. 83, 22, p. 4062-4077 15 p.

    Research output: Contribution to journal › Article › peer-review

  11. Published

    Economic analysis of treatments for children who do not achieve adequate asthma control when using low-dose inhaled corticosteroids

    Culeddu, G., Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Turner, S., Smith, C. T. & Hughes, D., 30 Jul 2024, In: Disease in Childhood. 109, suppl 1

    Research output: Contribution to journal › Conference article › peer-review

  12. Published

    Technostress, technosuffering and relational strain in contemporary general practice

    Dakin, F., Hemmings, N., Kalin, A., Moore, L., Ladds, E., Payne, R. E., Rosen, R., Byng, R., Wherton, J., Wieringa, S. & Greenhalgh, T., 8 Jan 2025, In: British Journal of General Practice.

    Research output: Contribution to journal › Article › peer-review

  13. E-pub ahead of print

    ‘ThinkCancer!’ – Randomised feasibility trial of a novel practice-based early cancer diagnosis intervention

    Disbeschl, S., Hendry, A., Surgey, A., Walker, D., Goulden, N., Anthony, B., Neal, R., Williams, N., Hoare, Z., Hiscock, J., Edwards, R. T., Lewis, R. & Wilkinson, C., 3 May 2024, (E-pub ahead of print) In: BJGP open.

    Research output: Contribution to journal › Article › peer-review

  14. Published

    Wellness in work - supporting people in work and assisting people to return to the workforce: An economic evidence review.

    Edwards, R. T., Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Makanjuola, A., Lloyd-Williams, H., Fitzsimmons, D., Collins, B., Charles, J., Lewis, R., Cooper, A., Barutcu, S. & McKibben, M.-A., 17 Jan 2024, MedRxiv.

    Research output: Working paper › Preprint

  15. Published

    A rapid review of the effectiveness and cost effectiveness of interventions that make homes warmer and cheaper to heat for households in fuel poverty in rural and remote areas

    Edwards, D., Csontos, J., Gillen, L., Carrier, J., Lewis, R., Cooper, A. & Edwards, A., 1 Jan 2024, MedRxiv, (MedRxiv).

    Research output: Working paper › Preprint

  16. Published

    Physical Activity Mobile App (CareFit) for Informal Carers of People With Dementia: Protocol for a Feasibility and Adaptation Study

    Egan, K., MacDonald, B., Hodgson, W., Kirk, A., Fawcett, B., Dunlop, M., Flynn, G., Stott, J. & Windle, G., 12 Sept 2024, In: Journal of Medical Internet Research. 13, 9 p., e53727.

    Research output: Contribution to journal › Article › peer-review

  17. Published

    Methodological approaches to measuring mental health in a cost-of-living crisis: A rapid review

    England, C., Jarrom, D., Washington, J., Hasler, E., Batten, L., Edwards, A. & Lewis, R., Jun 2024, In: Health Policy. 144, 105062.

    Research output: Contribution to journal › Article › peer-review

  18. Published

    Mentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multicentre, assessorblinded, randomised controlled trial

    Fonagy, P., Simes, E., Yirmiya, K., Wason, J., Barrett, B., Frater, A., Cameron, A., Butler, S., Hoare, Z., McMurran, M., Moran, P. A., Crawford, M., Pilling, S., Allison, E., Yakeley, J. & Bateman, A., 1 Mar 2025, In: Lancet Psychiatry. 12

    Research output: Contribution to journal › Article › peer-review

  19. Published

    Implementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya-individually randomised superiority trial

    Fonagy, P., Chammay, R. E., Ngunu, C., Kumar, M., Verdeli, L., Allison, E., Anani, G., Fearon, P., Fouad, F., Hoare, Z., Koyio, L., Moore, H., Nyandigisi, A., Pilling, S., Sender, H., Skordis, J., Evans, R., Jaoude, G. J. A., Madeghe, B., Maradian, S. P. A., O'Donnell, C., Simes, E., Truscott, A., Wambua, G. N. & Yator, O., 26 Mar 2024, In: Trials. 25, 1, 217.

    Research output: Contribution to journal › Article › peer-review

  20. Published

    Exploring the effects of Deep Brain Stimulation and vision on Tremor in Parkinson’s disease

    Fransson, P.-A., Nilsson, M., Niehorster , D., Nyström , M., Rehncrona, S., Tjernström, F., Magnusson, M., Johansson, R. & Patel, M., 25 Apr 2020, In: Journal of NeuroEngineering and Rehabilitation. . 17, 56.

    Research output: Contribution to journal › Article › peer-review

  21. Published

    Knowledge mobilisation of rapid evidence reviews to inform health and social care policy and practice in a public health emergency: appraisal of the Wales COVID-19 Evidence Centre processes and impact, 2021-23

    Gal, M., Cooper, A., Joseph-Williams, N., Doe, E., Lewis, R., Law, R.-J., Anstey, S., Davies, N., Walters, A., Orford, R., Collins, B., Trigg, L., Roberts, C., Meredith, S., Macey, S., Carson-Stevens, A., Greenwell, J., Coomber, F. & Edwards, A., 26 Nov 2024, In: PLoS ONE. 19, 11, p. e0314461

    Research output: Contribution to journal › Article › peer-review

  22. Published

    Influencing Factors for the Acceptability of Accessing HIV Pre-exposure Prophylaxis via Community Pharmacies in Wales

    Gillespie, D., Williams, A. D. N., Ma, R., Couzens, Z., Hood, K., Hughes, D. A., Mantzourani, E., Cochrane, E. & Wood, F., 10 Apr 2025, In: Health Expectations. 28, 2, p. e70247

    Research output: Contribution to journal › Article › peer-review

  23. Published

    Prognostic factors for a change in eye health or vision: A rapid review

    Hammond, G., Needham-Taylor, A., Bromham, N., Gillen, E., Searchfield, L., Lewis, R., Cooper, A., Edwards, A., Edwards, R. T. & Davies, J., 18 Jan 2024, MedRxiv.

    Research output: Working paper › Preprint

  24. Published

    Expert Insight Into the Use of eHealth Interventions to Aid Medication Adherence During COVID-19

    Hassan, A. & Davies, N., 21 Mar 2024, In: Patient Preference and Adherence. 18, p. 721-731 11 p.

    Research output: Contribution to journal › Article › peer-review

  25. E-pub ahead of print

    Setting the context for a complex dental intervention of role substitution in care homes: Initial process evaluation findings

    Hendry, A., Baker, S., McKenna, G., Tsakos, G., Chestnutt, I., Smith, C., Jones, V., O'Neill, C., Jenkins, A., Evans, R., Syed, S. S., Mirza, A., Harvey, M., Karki, A., Moons, K., Sandom, F., Donaldson, M., Lappin, C., Shepherd, K. & Brocklehurst, P., 27 Mar 2024, (E-pub ahead of print) In: Gerodontology. p. 1-12

    Research output: Contribution to journal › Article › peer-review

  26. Published

    Hidden systems in primary care cancer detection: an embedded qualitative intervention development study

    Hiscock, J., Law, R.-J., Brain, K., Smidts, S., Nafees, S., Williams, N., Rose , J., Lewis, R., Roberts, J., Hendry, A., Neal, R. & Wilkinson, C., Aug 2024, In: British Journal of General Practice. 74, 745, p. e544-e551

    Research output: Contribution to journal › Article › peer-review

  27. Published

    Understanding quantitative research: part 2

    Hoare, Z. & Hoe, J., 26 Feb 2013, In: Nursing Standard. 27, 18, p. 48-55; quiz 57

    Research output: Contribution to journal › Article › peer-review

  28. Published

    1151 Patients’ preferences for anti-epileptic drugs (aeds)

    Holmes, E., Baker, G. A., Jacoby, A., Ring, A., Marson, A. & Hughes, D., 2017, In: Journal of Neurology, Neurosurgery and Psychiatry. 88, S1, 3 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  29. Published

    Developing an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project

    Holmes, E., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Foster, D., Hardman, K., Bell, S., Marson, A., Hughes, D. & Noble, A. J., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 28-37 10 p.

    Research output: Contribution to journal › Article › peer-review

  30. Published

    Influence Of Disease Familiarity On Implied Time Preferences For Seizure Frequency Reduction.

    Holmes, E., Morrison, V. & Hughes, D., 1 Oct 2017, In: Value in Health. 20, 9, PA689.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  31. Published

    Balancing Patient Preferences With Feasible Healthcare Delivery: Using Discrete Choice Experiments Alongside Knowledge Exchange To Inform Care Pathways. International Journal of Technology Assessment in Health Care.

    Holmes, E., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Goodacre, S., Jackson, M. & Hughes, D., 7 Jan 2025, In: International Journal of Technology Assessment in Health Care. 40, S1, p. 178

    Research output: Contribution to journal › Meeting Abstract › peer-review

  32. Published

    A model-based cost-utility analysis of an automated notification system for deteriorating patients on general wards

    Holmes, E., Hughes, D. & Subbe, C., 2 May 2024, In: PLoS ONE. 19, 5, p. e0301643 e0301643.

    Research output: Contribution to journal › Article › peer-review

  33. Published

    Understanding the interactions that children and young people have with their natural and built environments: A survey to identify targets for active travel behaviour change in Wales

    Holmes, E., Arkesteijn, M., Knowles, K., McKinney, T., Mizen, A. & Purcell, C., 18 Oct 2024, In: PLoS ONE. 19, 10, 16 p., e0311498.

    Research output: Contribution to journal › Article › peer-review

  34. Published

    A novel approach to benefit-risk assessment of surgical resection of colorectal liver metastases.

    Holmes, E., Jones, L., Gollins, S., Hughes, D. & Fenwick, S., 1 Nov 2019, In: British Journal of Surgery. 106, p. 6-7

    Research output: Contribution to journal › Meeting Abstract › peer-review

  35. Published

    Seizure first aid training for people with epilepsy attending emergency departments and their significant others: the SAFE intervention and feasibility RCT

    Holmes, E., Noble, A. J., Nevitt, S., Holmes, E., Ridsdale, L., Morgan, M., Smith, C. T., Hughes, D., Goodacre, S., Marson, T. & Snape, D. A., 1 Oct 2020, In: Health and Social Care Delivery Research. 8, 39

    Research output: Contribution to journal › Article › peer-review

  36. Published

    Automated Systems For Hospital Inpatient Safety: A Cost-Utility Analysis.

    Holmes, E., Lloyd-Williams, H., Hughes, D. & Subbe, C., 7 Jan 2025, In: International Journal of Technology Assessment in Health Care. 40, S1, p. S100

    Research output: Contribution to journal › Meeting Abstract › peer-review

  37. Published

    Digital Remote Monitoring Using an mHealth Solution for Survivors of Cancer: Protocol for a Pilot Observational Study

    Innominato, P. F., Macdonald, J., Saxton, W., Longshaw, L., Granger, R., Naja, I., Allocca, C., Edwards, R., Rasheed, S., Folkvord, F., de Battle, J., Ail, R., Motta, E., Bale, C., Fuller, C., Mullard, A. P., Subbe, C., Griffiths, D., Wreglesworth, N., Pecchia, L., Fico, G. & Antonini, A., 30 Apr 2024, In: JMIR Research Protocols. 13, p. e52957 e52957.

    Research output: Contribution to journal › Article › peer-review

  38. Published

    Potential types of bias when estimating causal effects in environmental research and how to interpret them

    Konno, K., Gibbons, J., Lewis, R. & Pullin, A., 7 Feb 2024, In: Environmental Evidence. 13, 1, 1.

    Research output: Contribution to journal › Article › peer-review

  39. Published

    A bespoke rapid evidence review process engaging stakeholders for supporting evolving and time-sensitive policy and clinical decision-making: reflection and lessons learned from the Wales Covid-19 Evidence Centre 2021-23

    Lewis, R., Cooper, A., Jarrom, D., Mann, M., Law, R.-J., Edwards, D., Carrier, J., Shaw, H., Winfield, T., Spencer, L., Noyes, J., Morgan, H., Washington, J., Hasler, E., Gal, M., Doe, E., Joseph-Williams, N. & Edwards, A., 23 Jan 2024, Research Square.

    Research output: Working paper › Preprint

  40. E-pub ahead of print

    A randomised controlled trial of a digital intervention (Renewed) to support symptom management, wellbeing and quality of life in cancer survivors

    Little, P., Bradbury, K., Stuart, B., Barnett, J., Krusche, A., Steele, M., Heber, E., Easton, S., Smith, K. A., Slodowska-Barabasz, J., Payne, L., Corbett, T., Wilde, L., Yao, G. L., Pollet , S., Smith, J., Joseph, J., Lawrence, M., Böhning, D., Cheetham-Blake, T., Eccles, D., Foster, C., Geraghty, A. W. A., Leydon, G., Müller, A. M., Neal, R. D., Osborne, R., Rathod, S., Richardson, A., Grimmett, C., Sharman, G., Bacon, R., Turner, L., Stephens, R., Rogers, K., Raftery, J., Zhu , S., Singh, K., Webley, F., Griffiths, G., Nutall, J., Chalder, T., Wilkinson, C., Watson, E. & Yardley, L., 20 Dec 2023, (E-pub ahead of print) In: British Journal of General Practice.

    Research output: Contribution to journal › Article › peer-review

  41. Published

    Improving medication adherence in the community: a purposive umbrella review of effective patient-directed interventions that are readily implementable in the United Kingdom National Health Service

    Mackridge, A., Wood, E. & Hughes, D., 14 Mar 2025, In: International Journal of Clinical Pharmacy.

    Research output: Contribution to journal › Article › peer-review

  42. Published

    What are the most effective interventions to support children and young people bereaved by suicide in the family: a rapid review

    Mann, M., Kisleva, M., Searchfield, L., Mazzaschi, F., Jones, R., Lifford, K., Weightman, A., John, A., Lewis, R., Edwards, R. T., Davies, J., Cooper, A. & Edwards, A., 25 Sept 2023, MedRxiv.

    Research output: Working paper › Preprint

  43. Published

    Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial

    Marsden, J., Kelleher, M., Gilvarry, E., Mitcheson, L., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hardy, W., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Vanderwaal, R., Wareham, A., Hughes, D. & Hoare, Z., Dec 2023, In: eClinicalMedicine. 66, 23 p., 102331.

    Research output: Contribution to journal › Article › peer-review

  44. Published

    Hard to Reach and Hidden: Improving the Identification of Young Dementia Carers

    Masterson Algar, P., Egan, K., Flynn, G., Hughes, G., Spector, A., Stott, J. & Windle, G., 23 Nov 2023, In: International Journal of Environmental Research and Public Health. 20, 23, 15 p., 7103.

    Research output: Contribution to journal › Article › peer-review

  45. Published

    Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study

    Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L., Jul 2024, In: ACR Open Rheumatology. 6, 7, p. 403-411 9 p.

    Research output: Contribution to journal › Article › peer-review

  46. Published

    The experiences and perspectives of people with gout on urate self-monitoring

    Michael, T. J. F., Chan, J. S., Hughes, S., Wright, D. F. B., Coleshill, M. J., Hughes, D., Day, R. O., Aslani, P. & Stocker, S. L., Jun 2024, In: Health Expectations. 27, 3, 9 p., e14071.

    Research output: Contribution to journal › Article › peer-review

  47. Published

    Detection of endometrial cancer in cervico-vaginal fluid and blood plasma: Leveraging proteomics and machine learning for biomarker discover

    Njoku, K., Pierce, A., Chiasserini, D., Geary, B., Campbell, A. E., Kelsall, J., Reed, R., Geifman, N., Whetton, A. D. & Crosbie, E. J., Apr 2024, In: eBioMedicine. 102, p. 105064

    Research output: Contribution to journal › Article › peer-review

  48. Published

    Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project

    Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 17-27 11 p.

    Research output: Contribution to journal › Article › peer-review

  49. Published

    Interventions to mitigate the risks of COVID-19 for people experiencing homelessness and their effectiveness: a systematic review

    Ogbonna, O., Bull, F., Spinks, B., Williams, D., Lewis, R. & Edwards, A., 4 Jan 2024, In: Frontiers in Public Health. 11, 1286730.

    Research output: Contribution to journal › Article › peer-review

  50. Published

    Is Team‑Based Learning Efective for the Medical Student in Difculty?

    Patel, M., 12 Mar 2025, In: Medical Science Educator.

    Research output: Contribution to journal › Article › peer-review

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