Professor Dyfrig Hughes

Athro mewn Ffarmacoeconomeg / Cyfarwyddwr Ymchwil

  1. Published

    Pharmacoeconomics appraisals by the all Wales medicines strategy group

    Hughes, D. & Hughes, D. A., 1 Jul 2004.

    Research output: Contribution to conferencePaper

  2. Published

    Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.

    Hughes, D., Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., Van Eker, D., Stevens, L., Hawkins, K., Toh, C. H., Kamali, F., Daly, A. K., Fitzmaurice, D., Coffey, A., Williamson, P. R., Park, B. K., Deloukas, P. & Pirmohamed, M., 1 Oct 2009, In: Pharmacogenetics and Genomics. 19, 10, p. 800-812

    Research output: Contribution to journalArticlepeer-review

  3. Published

    The development of a QALY measure for epilepsy: NEWQOL-6D

    Hughes, D., Mulhern, B., Rowen, D., Jacoby, A., Marson, T., Snape, D., Hughes, D. A., Latimer, N., Baker, G. A. & Brazier, J. E., 1 May 2012, In: Epilepsy and Behavior. 24, 1, p. 36-43

    Research output: Contribution to journalArticlepeer-review

  4. Published

    Impact of pharmacogenetics on the costs of managing adverse events with warfarin: A prospective analysis.

    Hughes, D., Hughes, D. A., Al-Zubiedi, S., Hanson, A., Jorgensen, A. & Pirmohamed, M., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  5. Published

    Defining rewardable innovation in drug therapy

    Hughes, D., Aronson, J. K., Ferner, R. E. & Hughes, D. A., 1 Apr 2012, In: Nature Reviews Drug Discovery. 11, p. 253-254

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Statistical comments are unfounded.

    Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Mar 2008, In: Value in Health. 11, 2, p. 346

    Research output: Contribution to journalArticlepeer-review

  7. Published

    The impact of non-compliance on the cost-effectiveness of pharmaceuticals: A review of the literature.

    Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Oct 2001, In: Health Economics. 10, 7, p. 601-615

    Research output: Contribution to journalArticlepeer-review

  8. Published

    A single centre open phase IV study to evaluate the safety and tolerability of chlorproguanil-dapsone when dosed by defined height bands

    Hughes, D., Makanga, M., Winstanley, P. & Hughes, D. A., 1 Nov 2004.

    Research output: Contribution to conferencePaper

  9. Published

    Welsh Health Economics Network (WHEN): Scoping Report.

    Hughes, D., Farr, A., O Ceilleachair, A., Cohen, D., Hughes, D. A. & Phillips, C., 1 Jan 2005, 2005 ed. Unknown.

    Research output: Book/ReportCommissioned report

  10. Published

    Estimating Drug Costs in Economic Evaluations in Ireland and the UK: An Analysis of Practice and Research Recommendations.

    Hughes, D., Hughes, D. A., Tilson, L. & Drummond, M. F., 1 May 2009, In: Pharmacoeconomics. 27, 8, p. 635-643

    Research output: Contribution to journalArticlepeer-review

  11. Published

    Orphan drug treatments: economic considerations

    Hughes, D. & Hughes, D. A., 1 Nov 2007.

    Research output: Contribution to conferencePaper

  12. Published

    Clinical Pharmacology: Special safety considerations in drug development and pharmacovigilance.

    Hughes, D., Atuah, K. N., Hughes, D. A. & Pirmohamed, M., 1 Jan 2004, In: Drug Safety. 27, 8, p. 535-554

    Research output: Contribution to journalArticlepeer-review

  13. Published

    Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

    Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Aug 2007, In: Clinical Pharmacology and Therapeutics. 82, 2, p. 123-127

    Research output: Contribution to journalArticlepeer-review

  14. Published

    Quantitative risk-benefit analysis

    Hughes, D. & Hughes, D. A., 1 May 2007.

    Research output: Contribution to conferencePaper

  15. Published

    Impact of the abolition of the prescription charge in Wales.

    Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009, p. O41.

    Research output: Contribution to conferencePaper

  16. Published

    Ultra-long acting pharmaceuticals: Do they result in better outcomes, and at an acceptable cost?

    Hughes, D. & Hughes, D. A., 1 Nov 2006.

    Research output: Contribution to conferencePaper

  17. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Emtricitabine/tenofovir DF (Truvada)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  18. Published

    Pharmacoeconomic models that incorporate non-compliance

    Hughes, D. & Hughes, D. A., 1 Jul 2004.

    Research output: Contribution to conferencePaper

  19. Published
  20. Published

    The future challenges

    Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 167-174

    Research output: Chapter in Book/Report/Conference proceedingChapter

  21. Published

    The pharmacokinetic profile of Warfarn: a systematic review

    Hughes, D., Al-Zubiedi S.*, N. V., Hughes D.A., N. V. & Pirmohamed, M., 1 Dec 2007.

    Research output: Contribution to conferencePaper

  22. Published

    Warfarin pharmacogenetics: Economic considerations.

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Jan 2007, In: Pharmacoeconomics. 25, 11, p. 899-902

    Research output: Contribution to journalArticlepeer-review

  23. Published

    Public funding of drugs for orphan diseases

    Hughes, D. & Hughes, D. A., 1 Nov 2005.

    Research output: Contribution to conferencePaper

  24. Published

    Pharmacokinetic-Pharmacodynamic modelling of Lapdap (CPG-DDS) combination.

    Hughes, D., Hughes, D. A., Watkins, B. & Winstanley, P., 1 Jan 2001, 2001 ed. Unknown.

    Research output: Book/ReportCommissioned report

  25. Published

    Multiple imputation of multiple multi-item scales when a full imputation model is infeasible

    Hughes, D., Plumpton, C. O., Morris, T., Hughes, D. A. & White, I. R., 26 Jan 2016, In: BMC Research Notes. 9, 45, p. 1-15

    Research output: Contribution to journalArticlepeer-review

  26. Published

    Integrating compliance and persistence in health economics models

    Hughes, D. & Hughes, D. A., 1 Jan 2008.

    Research output: Contribution to conferencePaper

  27. Published
  28. Published

    Engaging with the MRC Methodology Hubs – NWHTMR.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  29. Published
  30. Published

    Impact of the abolition of the prescription charge in Wales.

    Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  31. Published

    Economic impact of poor compliance with pharmaceuticals.

    Hughes, D. & Hughes, D. A., 1 Aug 2002, In: Expert Review of Pharmacoeconomics and Outcomes Research. 2, 4, p. 327-335

    Research output: Contribution to journalArticlepeer-review

  32. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for STEMI.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  33. Published

    Evaluation of a consultant audit and feedback programme to improve the quality of antimicrobial prescribing in acute medical admissions

    Hughes, D., Roberts, E., Dawoud, D. M., Hughes, D. A. & Cefai, C., 1 Oct 2015, In: International Journal of Pharmacy Practice. 23, 5, p. 333-339

    Research output: Contribution to journalArticlepeer-review

  34. Published

    Development of an economic model to evaluate the cost-effectiveness of rival therapies for treating Crohn’s disease.

    Hughes, D., Kikuchi, T., Bodger, K. & Hughes, D. A., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  35. Published

    Eliciting patients' preferences using a discrete choice experiment questionnaire: the role played by qualitative data in questionnaire design

    Hughes, D., Longo, M., Hughes, D. A., Myles, S. & Lisles, C., 1 Mar 2006.

    Research output: Contribution to conferencePaper

  36. Published

    Improving Outcomes in Children and Young People with Cancer: Analysis of the Potential Economic Impact of the Guidance.

    Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2005, 2005 ed. Unknown.

    Research output: Book/ReportCommissioned report

  37. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  38. Published

    Public meetings of the NICE appraisals committee

    Hughes, D. & Hughes, D. A., 1 Dec 2007.

    Research output: Contribution to conferencePaper

  39. Published

    Impact of non-compliance on the cost-effectiveness of statin therapy

    Hughes, D., Hughes, D. A. & Bagust, A., 1 Sept 2001, In: Value in Health. 4, 6, p. 489

    Research output: Contribution to journalArticlepeer-review

  40. Published

    Use of PK-PD modelling to predict the impact of non-compliance

    Hughes, D. & Hughes, D. A., 1 Nov 2003.

    Research output: Contribution to conferencePaper

  41. Published

    Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses

    Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., N. V., 31 Oct 2011, In: British Medical Journal. 343, p. 1-14

    Research output: Contribution to journalArticlepeer-review

  42. Published

    All Wales Medicines Strategy Group Final Assessment Report – Agalsidase alfa (Replagal)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  43. Published

    A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)

    Hughes, D., Ramanan, A., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., Hickey, H., Hughes, D. A., Jones, A., Woo, P., Edelsten, C., Beresford, M. W. & The SYCAMORE Trail Management Group, N. V., 9 Jan 2014, In: Trials. 15, 14

    Research output: Contribution to journalArticlepeer-review

  44. Published

    The problem of orphan drugs

    Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Nov 2010, In: British Medical Journal. 341, p. 335-341

    Research output: Contribution to journalArticlepeer-review

  45. Published

    Back to basics: what is the relationship between dose and duration of drug action?

    Hughes, D. & Hughes, D. A., 1 May 2006.

    Research output: Contribution to conferencePaper

  46. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Chronic, accelerated or blast phase CML.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  47. Published

    The economics of evergreening.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  48. Published

    Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity

    Hughes, D., Hughes, D. A., Vilar, F. J., Ward, C. C., Alfirevic, A., Park, B. K. & Pirmohamed, M., 1 Jun 2004, In: Pharmacogenetics. 14, 6, p. 335-342

    Research output: Contribution to journalArticlepeer-review

  49. Published

    Drugs for exceptionally rare diseases: do they deserve special status for funding?

    Hughes, D., Tunnage, B. & Yeo, S. T., 1 Nov 2005, In: QJM - An International Journal of Medicine. 98, 11, p. 829-836

    Research output: Contribution to journalArticlepeer-review

  50. Published

    Is exercise effective in promoting mental well-being in older age? A systematic review.

    Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Aug 2010, In: Aging and Mental Health. 14, 6, p. 652-669

    Research output: Contribution to journalArticlepeer-review

  51. Published

    Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

    Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417

    Research output: Contribution to journalArticlepeer-review

  52. Published

    A parenting programme for children at risk of developing conduct disorder: A cost-effectiveness analysis

    Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 1 May 2007.

    Research output: Contribution to conferencePaper

  53. Published

    Economic evaluations during early (Phase II) drug development: A role for clinical trial simulations.

    Hughes, D., Hughes, D. A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 11, p. 1069-1077

    Research output: Contribution to journalArticlepeer-review

  54. Published
  55. Published

    Drug compliance and pharmaceconomics

    Hughes, D. & Hughes, D. A., 1 Dec 2003.

    Research output: Contribution to conferencePaper

  56. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Parathyroid hormone (Preotact)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  57. Published

    Methodological issues in the literature on costs of non-compliance in chronic diseases

    Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008.

    Research output: Contribution to conferencePaper

  58. Published

    Economic evaluation during early (phase II) trials

    Hughes, D. & Hughes, D. A., 1 Nov 2002.

    Research output: Contribution to conferencePaper

  59. Published

    Impact of the abolition of the prescription charge in Wales

    Hughes, D. & Hughes, D. A., 1 Nov 2008.

    Research output: Contribution to conferencePaper

  60. Published

    A prototype agent-based model of antimalarial drug compliance

    Hughes, D., McKean, J., Rahlf, S., Shorter, H., Barnish, G., Paton, R., McBurney, P., Hughes, D. A. & Hastings, I., 1 Aug 2007.

    Research output: Contribution to conferencePaper

  61. Published

    Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Nov 2003, In: Value in Health. 6, 6, p. 749

    Research output: Contribution to journalArticlepeer-review

  62. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conferencePaper

  63. Published

    Abolition of prescription copayments in Wales: an observational study on dispensing rates.

    Hughes, D., Cohen, D., Alam, M. F., Dunstan, F. D., Myles, S., Hughes, D. A. & Routledge, P. A., 1 Aug 2010, In: Value in Health. 13, 5, p. 675-680

    Research output: Contribution to journalArticlepeer-review

  64. Published

    Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations.

    Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Nov 2007, In: Value in Health. 10, 6, p. 498-509

    Research output: Contribution to journalArticlepeer-review

  65. Published

    Effects of the abolition of prescription charges in Wales: A preliminary analysis

    Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

    Research output: Contribution to conferencePaper

  66. Published

    Pharmacogenetic tests: the need for a level playing field

    Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4

    Research output: Contribution to journalArticlepeer-review

  67. Published

    What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?

    Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.

    Research output: Contribution to conferencePaper

  68. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-experienced patients.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  69. Published

    Adverse drug reactions in economic evaluations

    Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A109

    Research output: Contribution to journalArticlepeer-review

  70. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Tenofovir disoproxil fumarate (Viread) for the treatment of hepatitis B.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/ReportCommissioned report

  71. Published

    The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies.

    Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

    Research output: Book/ReportCommissioned report

  72. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Clofarabine (Evoltra)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/ReportCommissioned report

  73. Published

    Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.

    Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25

    Research output: Contribution to journalLetterpeer-review

  74. Published

    Health utilities and costs for neuromyelitis optica spectrum disorder

    Hughes, D., Bourke, S., Jones, A., Bhatt, R., Huda, S., Mutch, K. & Jacob, A., 2022, In: Orphanet Journal of Rare Diseases. 17, 11 p., 159.

    Research output: Contribution to journalArticlepeer-review

  75. Published

    Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study

    Hughes, D. & Poletti-Hughes, J., 21 Oct 2016, In: PLoS ONE. 11, 10, e0164681.

    Research output: Contribution to journalArticlepeer-review

  76. Published

    Economics of pharmacogenetic guided treatments: Underwhelming or overstated?

    Hughes, D., May 2018, In: Clinical Pharmacology and Therapeutics. 103, 5, p. 749-751

    Research output: Contribution to journalArticlepeer-review

  77. Published

    Rare disease prevention and treatment: The need for a level playing field

    Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247

    Research output: Contribution to journalArticlepeer-review

  78. Published

    Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam

    Hughes, D., Nov 2020, In: British Journal of Pharmacology. 177, 21, p. 4975-4989 15 p.

    Research output: Contribution to journalArticlepeer-review

  79. Published

    Management of Patients Symptomatically Unresponsive to Levothyroxine: Natural Desiccated Thyroid Extract or the Combination of Levothyroxine and Liothyronine? A Research Priority

    Hughes, D., Livingston, M. & Heald, A., Sept 2020, In: Experimental and Clinical Endocrinology & Diabetes . 128, 9, p. 596-598

    Research output: Contribution to journalLetterpeer-review

  80. Published

    Liothyronine for hypothyroidism: A candidate for disinvestment or in need of further research? A value of information analysis

    Hughes, D., Skiadas, K., Fitzsimmons, D., Anderson, P. & Heald, A., 3 Dec 2021, In: BMJ Open. 11, 12, e051702.

    Research output: Contribution to journalArticlepeer-review

  81. Published

    Medication adherence – key considerations for clinical pharmacologists

    Hughes, D., Apr 2020, In: British Journal of Clinical Pharmacology. 86, 4, p. 628-629 2 p.

    Research output: Contribution to journalEditorialpeer-review

  82. E-pub ahead of print

    We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment

    Hughes, D., 27 Sept 2023, (E-pub ahead of print) In: Health Economics, Policy and Law.

    Research output: Contribution to journalArticlepeer-review

  83. Published

    Medicines Shortages in the United Kingdom

    Hughes, D., Oct 2019, In: Clinical Pharmacology and Therapeutics. 106, 4, p. 712

    Research output: Contribution to journalLetterpeer-review

  84. Published

    Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis

    Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. 415-424

    Research output: Contribution to journalArticlepeer-review

  85. Published

    Impact of relaxing Covid-19 social distancing measures on rural North Wales: a simulation analysis

    Hughes, R. P. & Hughes, D., 14 Dec 2020, In: Frontiers in Public Health. 8, 562473.

    Research output: Contribution to journalArticlepeer-review

  86. Published

    The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial

    Jenkinson, M. D., Javadpour, M., Haylock, B. J., Young, B., Gillard, H., Vinten, J., Bulbeck, H., Das, K., Farrell, M., Looby, S., Hickey, H., Preusser, M., Mallucci, C. L., Hughes, D., Gamble, C. & Weber, D. C., 14 Nov 2015, In: Trials. 16

    Research output: Contribution to journalArticlepeer-review

  87. Published

    Letter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma

    Jenkinson, M., Weber, D., Haylock, B., Sherratt, F., Young, B., Weller, M., Bulbeck, H., Culeddu, G., Hughes, D., Brain, A., Das, K., Preusser, M., Francis, P. & Gamble, C., 17 Aug 2018, In: Journal of Neurology, Neurosurgery and Psychiatry.

    Research output: Contribution to journalLetterpeer-review

  88. Published

    Evidence to support inclusion of pharmacogenetic biomarkers in randomised controlled trials

    Johnson, D., Jorgensen, A., Hughes, D. & Pirmohamed, M., 1 Sept 2019, In: Journal of Personalized Medicine. 9, 3, 19 p., 42.

    Research output: Contribution to journalReview articlepeer-review

  89. Published
  90. Published

    Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial

    Johnson, S., Marshall, A., Hughes, D., Holmes, E., Henrich, F., Nurmikko, T., Sharma, M., Frank, B., Bassett, P., Marshall, A. & Goebel, A., 6 Nov 2021, In: Journal of Translational Medicine. 19, 1, 458.

    Research output: Contribution to journalArticlepeer-review

  91. Published

    A “Bundle of Care” to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study

    Jorgensen, AL., Waitt, C., Orrell, C., Cheng-Hock, T., Sekaggya-Wiltshire, C., Hughes, D., Allen, E., Okello, E., Tatz, G., Culeddu, G., Asiimwe, I. G., Semakula, J. R., Mouton, J. P., Cohen, K., Blockman, M., Lamorde, M. & Pirmohamed, M., 19 Jul 2023, In: Journal of Medical Internet Research. 12, e46710.

    Research output: Contribution to journalArticlepeer-review

  92. Published
  93. Published
  94. Published

    Nurse-led vs. conventional physician-led follow-up for patients with cancer: systematic review

    Lewis, R., Neal, R. D., Williams, N. H., France, B., Wilkinson, C. E., Hendry, M., Russell, D., Russell, I., Hughes, D., Stuart, N. S. & Weller, D., 1 Apr 2009, In: Journal of Advanced Nursing. 65, 4, p. 706-723

    Research output: Contribution to journalArticlepeer-review

  95. Published

    Patients' and healthcare professionals' views of cancer follow-up: systematic review

    Lewis, R., Neal, R. D., Hendry, M., France, B., Williams, N. H., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., Jul 2009, In: British Journal of General Practice. 59, 564, p. e248-e259

    Research output: Contribution to journalArticlepeer-review

  96. Published

    Follow-up of cancer in primary care versus secondary care: systematic review

    Lewis, R. A., Neal, R. D., Williams, N. H., France, B., Hendry, M., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., 1 Jul 2009, In: British Journal of General Practice. 59, 564, p. e234-e247

    Research output: Contribution to journalArticlepeer-review

  97. Published

    A Systematic Review of Economic Evaluations of Advanced Therapy Medicinal Products

    Lloyd Williams, H. & Hughes, D., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2428-2443 16 p.

    Research output: Contribution to journalReview articlepeer-review

  98. Published

    Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria

    Lotsch, F., Auer-Hackenberg, L., Groger, M., Rehman, K., Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., de Geest, S., Dobbels, F., Vrijens, B., Kardas, P., Hughes, D. & Ramharter, M., May 2015, In: Wiener klinische Wochenschrift. 127, 9-10, p. 379-384

    Research output: Contribution to journalArticlepeer-review

  99. Published

    Pharmacogenomics spotlight commentary: From the United Kingdom to global populations

    Magavern, E. F., Daly, A. K., Gilchrist, A. & Hughes, D., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4546-4548 3 p., 14917.

    Research output: Contribution to journalComment/debatepeer-review

  100. Published

    Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT

    Mallucci, C. L., Jenkinson, M., Conroy, E. J., Hartley, J. C., Brown, M., Moitt, T., Dalton, J., Kearns, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 2 Apr 2020, In: Health Technology Assessment. 24, 17, 114 p.

    Research output: Contribution to journalArticlepeer-review

  101. Published

    Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multi-centre, single-blinded, randomised trial and economic evaluation

    Mallucci, C. L., Jenkinson, M. D., Conroy, E. J., Hartley, J. C., Brown, M., Dalton, J., Kearns, T., Moitt, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 26 Oct 2019, In: The Lancet. 394, 10208, p. 1530-1539 10 p.

    Research output: Contribution to journalArticlepeer-review

  102. Published

    Extended-release pharmacotherapy for opioid use disorder (EXPO): protocol for an open-label randomised controlled trial of the effectiveness and cost-effectiveness of injectable buprenorphine versus sublingual tablet buprenorphine and oral liquid methadone

    Marsden, J., Kelleher, M., Hoare, Z., Hughes, D., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Scott, G., Turner, S., Vanderwaal, R., Wareham, A., Gilvarry, E. & Mitcheson, L., 19 Aug 2022, In: Trials. 23, 1, 697.

    Research output: Contribution to journalArticlepeer-review

  103. Published

    Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial

    Marsden, J., Kelleher, M., Gilvarry, E., Mitcheson, L., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hardy, W., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Vanderwaal, R., Wareham, A., Hughes, D. & Hoare, Z., Dec 2023, In: eClinicalMedicine. 66, 23 p., 102331.

    Research output: Contribution to journalArticlepeer-review

  104. Published

    The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

    Marson, A., Burnside, G., Appleton, R., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1375-1386

    Research output: Contribution to journalArticlepeer-review

  105. Published

    The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

    Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1363-1374

    Research output: Contribution to journalArticlepeer-review

  106. Published

    Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs

    Marson, A. G., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P. R., Baker, G., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., Dec 2021, In: Health Technology Assessment. 25, 75, 162 p.

    Research output: Contribution to journalArticlepeer-review

  107. Published

    Cost-effectiveness of home versus hospital management of children at onset of Type 1 Diabetes: The DECIDE randomised controlled trial

    McCarroll, Z., Townson, J., Pickles, T., Gregory, J. W., Playle, R., Robling, M. & Hughes, D., 19 May 2021, In: BMJ Open. 11, 5, e043523.

    Research output: Contribution to journalArticlepeer-review

  108. Published

    A Fully Integrated Real-Time Detection, Diagnosis, and Control of Community Diarrheal Disease Clusters and Outbreaks (the INTEGRATE Project): Protocol for an Enhanced Surveillance System

    McIntyre, K. M., Bolton, F. J., Christley, R. M., Cleary, P., Deja, E., Durie, A. E., Diggle, P. J., Hughes, D., de Lusignan, S., Orton, L., Radford, A. D., Elliot, A., Smith, G. E., Snape, D. A., Stanistreet, D., Vivancos, R., Winstanley, C. & O'Brien, S. J., 26 Sept 2019, In: JMIR Research Protocols. 8, 9, p. e13941 10 p., e13941.

    Research output: Contribution to journalArticlepeer-review

  109. Published

    Advanced therapy medicinal products: a comprehensive overview for pharmacy professionals

    McKenzie, C. A., Chappel, J., Guy, R. H., Hawksworth, G., Hughes, D. & Black, A., 12 Aug 2022, In: Pharmaceutical Journal.

    Research output: Contribution to journalArticlepeer-review

  110. E-pub ahead of print

    Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study

    Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L., 9 Apr 2024, (E-pub ahead of print) In: ACR Open Rheumatology.

    Research output: Contribution to journalArticlepeer-review

  111. Published

    The experiences and perspectives of people with gout on urate self-monitoring

    Michael, T. J. F., Chan, J. S., Hughes, S., Wright, D. F. B., Coleshill, M. J., Hughes, D., Day, R. O., Aslani, P. & Stocker, S. L., Jun 2024, In: Health Expectations. 27, 3, 9 p., e14071.

    Research output: Contribution to journalArticlepeer-review

  112. Published

    Economic Studies in Motor Neurone Disease: A Systematic Methodological Review

    Moore, A., Young, C. A. & Hughes, D., Apr 2017, In: Pharmacoeconomics. 35, 4, p. 397-413

    Research output: Contribution to journalArticlepeer-review

  113. Published

    Health utilities and costs for Motor Neurone Disease

    Moore, A., Young, C. A. & Hughes, D., Nov 2019, In: Value in Health. 22, 11, p. 1257-1265

    Research output: Contribution to journalArticlepeer-review

  114. Published

    Mapping ALSFRS-R and ALSUI to EQ-5D in patients with motor neurone disease

    Moore, A., Young, C. A. & Hughes, D., Nov 2018, In: Value in Health. 21, 11, p. 1322-1329

    Research output: Contribution to journalArticlepeer-review

  115. Published

    Predictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey

    Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Mar 2015, In: Value in Health. 18, 2, p. 206-216

    Research output: Contribution to journalArticlepeer-review

  116. Published

    ‘Seizure First Aid Training’ for people with epilepsy who attend emergency departments, and their family and friends: study protocol for intervention development and a pilot randomised controlled trial

    Noble, A. J., Marson, A. G., Tudur-Smith, C., Morgan, M., Hughes, D., Goodacre, S. & Ridsdale, L., 24 Jul 2015, In: BMJ Open. 5, 7

    Research output: Contribution to journalArticlepeer-review

  117. Published

    Seizure First Aid Training For people with Epilepsy (SAFE) frequently attending emergency departments and their significant others: results of a UK multi-centre randomised controlled pilot trial

    Noble, A. J., Snape, D., Nevitt, S., Holmes, E., Morgan, M., Smith, C. T., Hughes, D., Buchanan, M., McVicar, J., MacCallum, E., Goodacre, S., Rinsdale, L. & Marson, A. G., 16 Apr 2020, In: BMJ Open. 10, 4, e035516.

    Research output: Contribution to journalArticlepeer-review

  118. Published

    Developing patient-centred, feasible alternative care for adult emergency department users with epilepsy: Protocol for the mixed-methods observational ‘Collaborate’ project.

    Noble, A. J., Mathieson, A., Ridsdale, L., Holmes, E., Morgan, M., McKinlay, A., Dickson, J., Jackson, M., Hughes, D., Goodacre, S. & Marson, A. G., 2 Nov 2019, In: BMJ Open. 9, 11, e031696.

    Research output: Contribution to journalArticlepeer-review

  119. Accepted/In press

    Developing feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed methods study

    Noble, A. J., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Morris, B., Hughes, D., Marson, T. & Holmes, E., 6 Jun 2023, (Accepted/In press) In: Health Services and Delivery Research (HS&DR).

    Research output: Contribution to journalArticlepeer-review

  120. Published

    Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project

    Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 17-27 11 p.

    Research output: Contribution to journalArticlepeer-review

  121. Published

    Adverse drug reactions, multimorbidity and polypharmacy: A prospective analysis of one month of medical admissions

    Osanlou, R., Walker, L., Hughes, D., Burnside, G. & Pirmohamed, M., 4 Jul 2022, In: BMJ Open. 12, 7, e055551.

    Research output: Contribution to journalArticlepeer-review

  122. Published

    The Development of a Consistent Europe-Wide Approach to Investigating the Economic Impact of Myalgic Encephalomyelitis (ME/CFS): A Report from the European Network on ME/CFS (EUROMENE)

    Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 7 Apr 2020, In: Healthcare. 8, 2, 88.

    Research output: Contribution to journalArticlepeer-review

  123. Published

    The role of prevention in reducing the economic impact of ME/CFS in Europe: A report from the socioeconomics working group of the European Network on ME/CFS (EUROMENE).

    Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 16 Apr 2021, In: Medicina. 57, 4, 388.

    Research output: Contribution to journalArticlepeer-review

  124. Published

    A Literature Review of GP Knowledge and Understanding of ME/CFS: A Report from the Socioeconomics Working Group of the European Network on ME/CFS (EUROMENE)

    Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., Jan 2021, In: Medicina. 57, 1, 17 p., 7.

    Research output: Contribution to journalArticlepeer-review

  125. Published

    Costs of orphan medicinal products: longitudinal analysis of expenditure in Wales

    Pijeira Perez, Y., Wood, E. & Hughes, D., 1 Nov 2023, In: Orphanet Journal of Rare Diseases. 18, 1, 342.

    Research output: Contribution to journalArticlepeer-review

  126. Published

    Cost effectiveness of pharmacogenetic screening prior to initiation of carbamazepine treatment for epilepsy

    Plumpton, C. O., Yip, V., Alfirevic, A., Marson, A., Pirmohamed, M. & Hughes, D., Nov 2013, In: Value in Health. 16, 7, p. A624-A624

    Research output: Contribution to journalArticlepeer-review

  127. Published

    Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout

    Plumpton, C., Alfirevic, A., Pirmohamed, M. & Hughes, D., 1 Oct 2017, In: Rheumatology. 56, 10, p. 1729-1739

    Research output: Contribution to journalArticlepeer-review

  128. Published

    Cost-effectiveness of HLA-B*15:02 screening in Malaysia

    Plumpton, C. & Hughes, D., Oct 2017, In: British Journal of Dermatology. 177, 4, p. 904-905

    Research output: Contribution to journalComment/debate

  129. Published

    Cost-effectiveness of screening for HLA-A*31:01 prior to initiation of carbamazepine in epilepsy

    Plumpton, C., Yip, V. L. M., Alfirevic, A., Marson, A. G., Pirmohamed, M. & Hughes, D., Apr 2015, In: Epilepsia.

    Research output: Contribution to journalArticlepeer-review

  130. Published

    Cost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework

    Plumpton, C., Pirmohamed, M. & Hughes, D., Jun 2019, In: Clinical Pharmacology and Therapeutics. 105, 6, p. 1429-1438

    Research output: Contribution to journalArticlepeer-review

  131. Published

    A systematic review of economic evaluations of pharmacogenetic testing for prevention of adverse drug reactions

    Plumpton, C. O., Roberts, D., Pirmohamed, M. & Hughes, D. A., Aug 2016, In: Pharmacoeconomics. 34, 8, p. 771-793

    Research output: Contribution to journalArticlepeer-review

  132. Published

    CARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial

    Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Feb 2019, In: Trials. 20, 1, 16 p., 105.

    Research output: Contribution to journalArticlepeer-review

  133. Published

    Carer administration of as-needed sub-cutaneous medication for breakthrough symptoms in people dying at home: the CARiAD feasibility RCT

    Poolman, M., Roberts, J., Wright, S., Hendry, A., Goulden, N., Holmes, E., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., O'Connor, J., Foster, B., Reymond, L., Healy, S., Lewis, P., Wee, B., Johnstone, R. P., Roberts, R., Parkinson, A., Roberts, S. & Wilkinson, C., 2 Jun 2020, In: Health Technology Assessment. 24, 25, 150 p.

    Research output: Contribution to journalArticlepeer-review

  134. Published

    Pharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery

    Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Jul 2015, In: British Journal of Clinical Pharmacology. 80, 5, p. 1149-1159

    Research output: Contribution to journalArticlepeer-review

  135. Published

    Using Routinely Recorded Data in the UK to Assess Outcomes in a Randomised Controlled Trial: The Trials of Access

    Powell, G., Bonnett, L., Smith, C. T., Hughes, D., Williamson, P. & Marson, A., 23 Aug 2017, In: Trials. 18, 11 p., 389.

    Research output: Contribution to journalArticlepeer-review

  136. Published

    Using Routinely Recorded Data in a UK RCT: A Comparison to Standard Prospective Data Collection Methods

    Powell, G., Bonnett, L., Tudor-Smith, C., Hughes, D., Williamson, P. R. & Marson, A. G., 5 Jul 2021, In: Trials. 22, 1, 429.

    Research output: Contribution to journalArticlepeer-review

  137. Published

    Do guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review

    Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Jul 2018, In: Thorax. 73, 7, p. 670-673

    Research output: Contribution to journalLetterpeer-review

  138. Published

    Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT

    Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D., McKay, A., Rosala_Hanna, A., Williamson, P. R., Hardwick, B., Hickey, H., Rainford, N., Kolamunnage-Dona, R., Culeddu, G., Plumpton, C., Wood, E., Compeyrot-Lacassagne, S., Woo, P., Eldesten, C. & Beresford, M. W., 10 Apr 2019, In: Health Technology Assessment. 23, 15, p. 1-174 174 p.

    Research output: Contribution to journalArticlepeer-review

  139. Published

    Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis

    Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., Hardwick, B., Hickey, H., Hughes, D., Woo, P., Benton, D., Edelsten, C. & Beresford, M. W., 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1637-1646

    Research output: Contribution to journalArticlepeer-review

  140. Published

    Development of a Database of Instruments for Resource-Use Measurement: Purpose, Feasibility, and Design

    DIRUM Team, 1 Jul 2012, In: Value in Health. 15, 5, p. 650-655

    Research output: Contribution to journalArticlepeer-review

  141. Published

    Methods for the collection of resource use data within clinical trials: A systematic review of studies funded by the UK Health Technology Assessment Program

    Ridyard, C. H. & Hughes, D., 1 Dec 2010, In: Value in Health. 13, 8, p. 867-872

    Research output: Contribution to journalArticlepeer-review

  142. Published

    A Systematic Review of Patient Preferences for Subcutaneous Medications

    Ridyard, C., Dawoud, D. & Hughes, D., Nov 2013.

    Research output: Contribution to conferencePaperpeer-review

  143. Published
  144. Published

    Continuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis

    Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A582

    Research output: Contribution to journalArticlepeer-review

  145. Published

    Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

    Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A590

    Research output: Contribution to journalArticlepeer-review

  146. Published
  147. Published

    A systematic review of patients' perspectives on the subcutaneous route of medication administration

    Ridyard, C., Dawoud, D. M., Tuersley, L. V. & Hughes, D., Aug 2016, In: Patient: Patient–Centered Outcomes Research. 9, 4, p. 281-292

    Research output: Contribution to journalArticlepeer-review

  148. Published

    Taxonomy for methods of resource use measurement

    DIRUM Team, 23 Jan 2015, In: Health Economics. 24, 3, p. 372-378

    Research output: Contribution to journalLetterpeer-review

  149. Published

    Cost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial

    Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Sept 2017, In: Frontiers in Pharmacology. 8, 644.

    Research output: Contribution to journalArticlepeer-review

  150. Published

    Review of resource-use measures in UK economic evaluations

    Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (eds.). University of Kent, Canterbury, p. 22-31 10 p.

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  151. Published
  152. Published
  153. Published

    Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

    Ridyard, C., Blair, J. & Hughes, D., Nov 2017, In: Value in Health. 20, 9, p. A481 - A482

    Research output: Contribution to journalArticlepeer-review

  154. Published

    What really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK

    Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Jun 2019, In: Epilepsy and Behavior. 95, p. 181-191

    Research output: Contribution to journalArticlepeer-review

  155. Published

    Enhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.

    Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Jan 2010.

    Research output: Contribution to conferencePaper

  156. Published

    Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial.

    Russell, I. T., Slegg, G. P., Roberts, S. H., Bedson, E., Hughes, D., Lloyd, K., Moat, S., Pirmohamed, M., Slegg, G., Tranter, R., Whitaker, R., Wilkinson, C. & Russell, I., 15 Nov 2007, In: BMC Psychiatry. 7, 1, p. 65

    Research output: Contribution to journalArticlepeer-review

  157. Published

    Supply-side cost-effectiveness thresholds: questions for evidence-based policy

    Sampson, C., Zamora, B., Watson, S., Cairns, J., Chalkidou, K., Cubi-Molla, P., Devlin, N., García-Lorenzo, B., Hughes, D., Leech, A. & Towse, A., Sept 2022, In: Applied Health Economics and Health Policy. 20, 5, p. 651-667

    Research output: Contribution to journalArticlepeer-review

  158. Published

    Opportunity costs and local health service spending decisions: a qualitative study from Wales

    Schaffer, S. K., Sussex, J., Hughes, D. & Devlin, N., 25 Mar 2016, In: BMC Health Services Research. 16, 103

    Research output: Contribution to journalArticlepeer-review

  159. Published

    Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone.

    Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, G., Watkins, W. A. & Ward, S., 1 Mar 2006, In: British Journal of Clinical Pharmacology. 61, 3, p. 289-300

    Research output: Contribution to journalArticlepeer-review

  160. Published

    Clinical interventions to improve adherence to urate-lowering therapy in patients with gout: a systematic review

    Sinnappah, K. A., Stocker, S. L., Chan, J. S., Hughes, D. A. & Wright, D. F. B., 25 Jun 2022, In: International Journal of Pharmacy Practice. 30, 3, p. 215-225 11 p.

    Research output: Contribution to journalArticlepeer-review

  161. E-pub ahead of print

    A framework for understanding sources of bias in medication adherence research

    Sinnappah, K. A., Hughes, D., Stocker, S. L., Vrijens, B., Aronson, J. K. & Wright, D. F. B., 26 Jul 2023, (E-pub ahead of print) In: British Journal of Clinical Pharmacology.

    Research output: Contribution to journalArticlepeer-review

  162. Published

    Cost and clinical consequence of antibiotic non-adherence in acute exacerbations of chronic bronchitis.

    Sorensen, S. V., Baker, T., Fleurence, R., Dixon, J., Roberts, C., Haider, S. & Hughes, D., 1 Aug 2009, In: International Journal of Tuberculosis and Lung Disease. 13, 8, p. 945-954

    Research output: Contribution to journalArticlepeer-review

  163. Published
  164. Published

    The costs and cost-effectiveness of different service models of palliatice care, focusing on end of life care: A rapid review

    Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Gillen, E., Noyes, J., Fitzsimmons, D., Lewis, R., Cooper, A., Hughes, D., Edwards, R. T. & Edwards, A., 7 Mar 2024, MedRxiv, 118 p.

    Research output: Working paperPreprint

  165. Published
  166. Published
  167. Published
  168. Published
  169. Published

    What is the long-term impact of COVID-19 on the Health-Related Quality of Life of individuals with mild symptoms (or non-hospitalised): A rapid review

    Spencer, L., Hendry, A., Makanjuola, A., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 9 Sept 2022, Health and Care Research Wales, 47 p.

    Research output: Working paperPreprint

  170. Published
  171. Published

    Value of improving patient safety: Health-economic considerations for Rapid Response Systems – a Rapid Review of the Literature and Expert Round Table

    Subbe, C., Hughes, D., Lewis, S., Holmes, E., Kalkman, C. J., So, R. K., Tranka, S. & Welch, J., 17 Apr 2023, In: BMJ Open. 13, 4, e065819.

    Research output: Contribution to journalArticlepeer-review

  172. Published

    Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care

    Swift, B., Jain, L., White, C., Chandrasekaran, V., Bhandari, A., Hughes, D. & Jadhav, P., Sept 2018, In: Clinical and Translational Science. 11, 5, p. 450-460 11 p.

    Research output: Contribution to journalArticlepeer-review

  173. Published

    Core items for a standardized resource-use measure (ISRUM): expert Delphi consensus survey

    Thom, J., Brookes, S. T., Ridyard, C., Riley, R., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., Jun 2018, In: Value in Health. 21, 6, p. 640-649

    Research output: Contribution to journalArticlepeer-review

  174. Published

    Resource-Use Measurement Based on Patient Recall: Issues and Challenges for Economic Evaluation

    Thorn, J. C., Coast, J., Cohen, D., Hollingworth, W., Knapp, M., Noble, S. M., Ridyard, C. H., Wordsworth, S. & Hughes, D., 1 Jun 2013, In: Applied Health Economics and Health Policy. 11, 3, p. 155-161

    Research output: Contribution to journalArticlepeer-review

  175. Published

    Identification Of Items For A Standardised Resource-Use Measure: Review Of Current Instruments

    Thorn, J. C., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S. & Hollingworth, W., Nov 2015.

    Research output: Contribution to conferencePaperpeer-review

  176. Published

    Core items for a standardised resource-use measure (ISRUM):expert Delphi consensus survey

    Thorn, J., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., 7 May 2017, p. P265. 1 p.

    Research output: Contribution to conferencePosterpeer-review

  177. Published

    Health economics analysis plans: the current state of play

    Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 7 May 2017, p. P144. 1 p.

    Research output: Contribution to conferencePosterpeer-review

  178. Published

    Health Economics Analysis Plans: Where Are We Now?

    Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 3 Nov 2016, p. A397. 1 p.

    Research output: Contribution to conferencePosterpeer-review

  179. Published

    Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey

    Thorn, J., Davies, C. F., Brookes, S., Noble, S., Dritsaki, M., Gray, E., Hughes, D., Mihaylova, B., Petrou, S., Ridyard, C., Sach, T., Wilson, E., Wordsworth, S. & Hollingworth, W., 1 Apr 2021, In: Value in Health. 24, 4, p. 539-547 9 p.

    Research output: Contribution to journalArticlepeer-review

  180. Published

    Appropriate design and reporting of superiority, equivalence and non-inferiority clinical trials incorporating a benefit risk assessment: the BRAINS study including expert workshop

    Totton, N., Julious, S., Coates, E., Hughes, D., Cook, J., Biggs, K., Hewitt, C., Day, S. & Cooke, A., Oct 2023, In: Health Technology Assessment. 27, 20, 86 p.

    Research output: Contribution to journalArticlepeer-review

  181. Published

    Utilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project

    Totton, N., Julious, S., Hughes, D., Cook, J., Biggs, K., Coates, L., Cook, A., Hewitt, C. & Day, S., 19 Jan 2021, In: Trials. 22, 68.

    Research output: Contribution to journalArticlepeer-review

  182. Published

    Acceptability of generic versus innovator oral medicines: not only a matter of taste

    Tuleu, C., Hughes, D., Clapham, D., Vallet, T. & Ruiz, F., Feb 2021, In: Drug Discovery Today. 26, 2, p. 329-343

    Research output: Contribution to journalArticlepeer-review

  183. Published

    New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes

    Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., May 2018, In: Pharmacoeconomics. 36, 5, p. 613-624 12 p.

    Research output: Contribution to journalArticlepeer-review

  184. Published

    Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden

    Verhoef, T. I., Redekop, W. K., Langenskiold, S., Kamali, F., Wadelius, M., Burnside, G., Maitland-van der Zee, A. H., Hughes, D. & Pirmohamed, M., Oct 2016, In: The Pharmacogenomics Journal. 16, p. 478–484

    Research output: Contribution to journalArticlepeer-review

  185. Published

    Trends and influences on use of antidiabetic drugs in England, 1992-2003.

    Walley, T., Hughes, D. & Kendall, H., 1 Nov 2005, In: Pharmacoepidemiology and Drug Safety. 14, 11, p. 769-773

    Research output: Contribution to journalArticlepeer-review

  186. Published

    Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation

    Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. G. & Williamson, P., 1 May 2021, In: The Lancet Rheumatology. 3, 5, p. e347-e356

    Research output: Contribution to journalArticlepeer-review

  187. Published

    Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT

    Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Bostock, J., Hay, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. & Williamson, P. R., Apr 2021, In: Health Technology Assessment. 25, 24, 86 p.

    Research output: Contribution to journalArticlepeer-review

  188. Published

    Carer-administration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARIAD)

    Wilkinson, C., Poolman, M., Roberts, J., Wee, B., Hiscock, J., Hughes, D., Nelson, A., Perkins, P., Johnstone, R. P., Reymond, E., Foster, B., O'Connor, J., Jones, S., Hoare, Z., Roberts, R., Byrne, A., Healy, S. & Lewis, P., 1 Sept 2017.

    Research output: Contribution to conferencePosterpeer-review

  189. Published

    Lessons learnt from a discontinued randomised controlled trial: Adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC)

    Williams, N., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Jul 2018, In: Trials. 19, 408.

    Research output: Contribution to journalArticlepeer-review

  190. Published

    Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica

    Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Oct 2017, In: Health Technology Assessment. 21, 60, p. 1-180 180 p.

    Research output: Contribution to journalArticlepeer-review

  191. Published

    Effectiveness of out-patient based acute heart failure care: A pilot randomised controlled trial

    Wong, K. Y. K., Hughes, D., Debski, M., Latt, N., Assaf, O., Abdelrahman, A., Taylor, R., Allgar, V., McNeill, L., Howard, S., Wong, S. Y. S., Jones, R., Cassidy, C. J., Seed, A., Galasko, G., Clark, A., Davis, G. K., Montasem, A., Lang, C. C., Kalra, P. R., Campbell, R., Lip, G. Y. H. & Cleland, J. G. F., Oct 2023, In: Acta Cardiologica. 78, 7, p. 828-837 10 p.

    Research output: Contribution to journalArticlepeer-review

  192. Published

    The new and non-transparent Cancer Drugs Fund

    Wood, E. & Hughes, D., Jan 2020, In: PharmacoEconomics. 38, 1, p. 1-4

    Research output: Contribution to journalArticlepeer-review

  193. Published

    Medication adherence research comes of age

    Wright, D. F. B., Sinnappah, K. A. & Hughes, D., Jul 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 1914-1917

    Research output: Contribution to journalEditorialpeer-review

  194. Published

    Improving Medication Adherence Research Reporting: European Society for Patient Adherence, Compliance and Persistence Medication Adherence Reporting Guideline

    de Geest, S., Zullig, L., Dunbar-Jacobs, J., Hughes, D., Wilson, I. & Vrijens, B., Jun 2019, In: Journal of Cardiovascular Nursing. 34, 3, p. 199-200

    Research output: Contribution to journalEditorialpeer-review

  195. Published

    Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

    de Geest, S., Zullig, L. L., Dunbar-Jacob, J., Hughes, D., Wilson, I. & Vrijens, B., 1 Apr 2019, In: European Journal of Cardiovascular Nursing. 18, 4, p. 258-259 2 p.

    Research output: Contribution to journalEditorialpeer-review

  196. E-pub ahead of print

    Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial

    SuMMiT-D Collaborative Group , 25 Jan 2024, (E-pub ahead of print) In: Pilot and Feasibility Studies. 10, 1, 15.

    Research output: Contribution to journalArticlepeer-review

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