1. Published

   Pharmacoeconomics appraisals by the all Wales medicines strategy group

   Hughes, D. & Hughes, D. A., 1 Jul 2004.

   Research output: Contribution to conference › Paper

2. Published

   Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.

   Hughes, D., Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., Van Eker, D., Stevens, L., Hawkins, K., Toh, C. H., Kamali, F., Daly, A. K., Fitzmaurice, D., Coffey, A., Williamson, P. R., Park, B. K., Deloukas, P. & Pirmohamed, M., 1 Oct 2009, In: Pharmacogenetics and Genomics. 19, 10, p. 800-812

   Research output: Contribution to journal › Article › peer-review

3. Published

   The development of a QALY measure for epilepsy: NEWQOL-6D

   Hughes, D., Mulhern, B., Rowen, D., Jacoby, A., Marson, T., Snape, D., Hughes, D. A., Latimer, N., Baker, G. A. & Brazier, J. E., 1 May 2012, In: Epilepsy and Behavior. 24, 1, p. 36-43

   Research output: Contribution to journal › Article › peer-review

4. Published

   Impact of pharmacogenetics on the costs of managing adverse events with warfarin: A prospective analysis.

   Hughes, D., Hughes, D. A., Al-Zubiedi, S., Hanson, A., Jorgensen, A. & Pirmohamed, M., 1 Jan 2009.

   Research output: Contribution to conference › Paper

5. Published

   Defining rewardable innovation in drug therapy

   Hughes, D., Aronson, J. K., Ferner, R. E. & Hughes, D. A., 1 Apr 2012, In: Nature Reviews Drug Discovery. 11, p. 253-254

   Research output: Contribution to journal › Article › peer-review

6. Published

   Statistical comments are unfounded.

   Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Mar 2008, In: Value in Health. 11, 2, p. 346

   Research output: Contribution to journal › Article › peer-review

7. Published

   The impact of non-compliance on the cost-effectiveness of pharmaceuticals: A review of the literature.

   Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Oct 2001, In: Health Economics. 10, 7, p. 601-615

   Research output: Contribution to journal › Article › peer-review

8. Published

   A single centre open phase IV study to evaluate the safety and tolerability of chlorproguanil-dapsone when dosed by defined height bands

   Hughes, D., Makanga, M., Winstanley, P. & Hughes, D. A., 1 Nov 2004.

   Research output: Contribution to conference › Paper

9. Published

   Welsh Health Economics Network (WHEN): Scoping Report.

   Hughes, D., Farr, A., O Ceilleachair, A., Cohen, D., Hughes, D. A. & Phillips, C., 1 Jan 2005, 2005 ed. Unknown.

   Research output: Book/Report › Commissioned report

10. Published

    Estimating Drug Costs in Economic Evaluations in Ireland and the UK: An Analysis of Practice and Research Recommendations.

    Hughes, D., Hughes, D. A., Tilson, L. & Drummond, M. F., 1 May 2009, In: Pharmacoeconomics. 27, 8, p. 635-643

    Research output: Contribution to journal › Article › peer-review

11. Published

    Orphan drug treatments: economic considerations

    Hughes, D. & Hughes, D. A., 1 Nov 2007.

    Research output: Contribution to conference › Paper

12. Published

    Clinical Pharmacology: Special safety considerations in drug development and pharmacovigilance.

    Hughes, D., Atuah, K. N., Hughes, D. A. & Pirmohamed, M., 1 Jan 2004, In: Drug Safety. 27, 8, p. 535-554

    Research output: Contribution to journal › Article › peer-review

13. Published

    Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

    Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Aug 2007, In: Clinical Pharmacology and Therapeutics. 82, 2, p. 123-127

    Research output: Contribution to journal › Article › peer-review

14. Published

    Quantitative risk-benefit analysis

    Hughes, D. & Hughes, D. A., 1 May 2007.

    Research output: Contribution to conference › Paper

15. Published

    Impact of the abolition of the prescription charge in Wales.

    Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009, p. O41.

    Research output: Contribution to conference › Paper

16. Published

    Ultra-long acting pharmaceuticals: Do they result in better outcomes, and at an acceptable cost?

    Hughes, D. & Hughes, D. A., 1 Nov 2006.

    Research output: Contribution to conference › Paper

17. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Emtricitabine/tenofovir DF (Truvada)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

18. Published

    Pharmacoeconomic models that incorporate non-compliance

    Hughes, D. & Hughes, D. A., 1 Jul 2004.

    Research output: Contribution to conference › Paper

19. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Icatibant (Firazyr) for symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults (with C1-esterase-inhibitor deficiency).

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

20. Published

    The future challenges

    Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 167-174

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

21. Published

    The pharmacokinetic profile of Warfarn: a systematic review

    Hughes, D., Al-Zubiedi S.*, N. V., Hughes D.A., N. V. & Pirmohamed, M., 1 Dec 2007.

    Research output: Contribution to conference › Paper

22. Published

    Warfarin pharmacogenetics: Economic considerations.

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Jan 2007, In: Pharmacoeconomics. 25, 11, p. 899-902

    Research output: Contribution to journal › Article › peer-review

23. Published

    Public funding of drugs for orphan diseases

    Hughes, D. & Hughes, D. A., 1 Nov 2005.

    Research output: Contribution to conference › Paper

24. Published

    Pharmacokinetic-Pharmacodynamic modelling of Lapdap (CPG-DDS) combination.

    Hughes, D., Hughes, D. A., Watkins, B. & Winstanley, P., 1 Jan 2001, 2001 ed. Unknown.

    Research output: Book/Report › Commissioned report

25. Published

    Multiple imputation of multiple multi-item scales when a full imputation model is infeasible

    Hughes, D., Plumpton, C. O., Morris, T., Hughes, D. A. & White, I. R., 26 Jan 2016, In: BMC Research Notes. 9, 45, p. 1-15

    Research output: Contribution to journal › Article › peer-review

26. Published

    Integrating compliance and persistence in health economics models

    Hughes, D. & Hughes, D. A., 1 Jan 2008.

    Research output: Contribution to conference › Paper

27. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Abacavir 600mg/lamivudine 300mg (Kivexa) in antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus infection in adults and adolescents from 12 years of age.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

28. Published

    Engaging with the MRC Methodology Hubs – NWHTMR.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conference › Paper

29. Published

    Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment

    Hughes, D., Myles, S., Hughes, D. A., Longo, M. & Lisles, C., 1 Jun 2006.

    Research output: Contribution to conference › Paper

30. Published

    Impact of the abolition of the prescription charge in Wales.

    Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.

    Research output: Contribution to conference › Paper

31. Published

    Economic impact of poor compliance with pharmaceuticals.

    Hughes, D. & Hughes, D. A., 1 Aug 2002, In: Expert Review of Pharmacoeconomics and Outcomes Research. 2, 4, p. 327-335

    Research output: Contribution to journal › Article › peer-review

32. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for STEMI.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

33. Published

    Evaluation of a consultant audit and feedback programme to improve the quality of antimicrobial prescribing in acute medical admissions

    Hughes, D., Roberts, E., Dawoud, D. M., Hughes, D. A. & Cefai, C., 1 Oct 2015, In: International Journal of Pharmacy Practice. 23, 5, p. 333-339

    Research output: Contribution to journal › Article › peer-review

34. Published

    Development of an economic model to evaluate the cost-effectiveness of rival therapies for treating Crohn’s disease.

    Hughes, D., Kikuchi, T., Bodger, K. & Hughes, D. A., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

35. Published

    Eliciting patients' preferences using a discrete choice experiment questionnaire: the role played by qualitative data in questionnaire design

    Hughes, D., Longo, M., Hughes, D. A., Myles, S. & Lisles, C., 1 Mar 2006.

    Research output: Contribution to conference › Paper

36. Published

    Improving Outcomes in Children and Young People with Cancer: Analysis of the Potential Economic Impact of the Guidance.

    Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2005, 2005 ed. Unknown.

    Research output: Book/Report › Commissioned report

37. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conference › Paper

38. Published

    Public meetings of the NICE appraisals committee

    Hughes, D. & Hughes, D. A., 1 Dec 2007.

    Research output: Contribution to conference › Paper

39. Published

    Impact of non-compliance on the cost-effectiveness of statin therapy

    Hughes, D., Hughes, D. A. & Bagust, A., 1 Sept 2001, In: Value in Health. 4, 6, p. 489

    Research output: Contribution to journal › Article › peer-review

40. Published

    Use of PK-PD modelling to predict the impact of non-compliance

    Hughes, D. & Hughes, D. A., 1 Nov 2003.

    Research output: Contribution to conference › Paper

41. Published

    Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses

    Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., N. V., 31 Oct 2011, In: British Medical Journal. 343, p. 1-14

    Research output: Contribution to journal › Article › peer-review

42. Published

    All Wales Medicines Strategy Group Final Assessment Report – Agalsidase alfa (Replagal)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

43. Published

    A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)

    Hughes, D., Ramanan, A., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., Hickey, H., Hughes, D. A., Jones, A., Woo, P., Edelsten, C., Beresford, M. W. & The SYCAMORE Trail Management Group, N. V., 9 Jan 2014, In: Trials. 15, 14

    Research output: Contribution to journal › Article › peer-review

44. Published

    The problem of orphan drugs

    Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Nov 2010, In: British Medical Journal. 341, p. 335-341

    Research output: Contribution to journal › Article › peer-review

45. Published

    Back to basics: what is the relationship between dose and duration of drug action?

    Hughes, D. & Hughes, D. A., 1 May 2006.

    Research output: Contribution to conference › Paper

46. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Chronic, accelerated or blast phase CML.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

47. Published

    The economics of evergreening.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conference › Paper

48. Published

    Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity

    Hughes, D., Hughes, D. A., Vilar, F. J., Ward, C. C., Alfirevic, A., Park, B. K. & Pirmohamed, M., 1 Jun 2004, In: Pharmacogenetics. 14, 6, p. 335-342

    Research output: Contribution to journal › Article › peer-review

49. Published

    Drugs for exceptionally rare diseases: do they deserve special status for funding?

    Hughes, D., Tunnage, B. & Yeo, S. T., 1 Nov 2005, In: QJM - An International Journal of Medicine. 98, 11, p. 829-836

    Research output: Contribution to journal › Article › peer-review

50. Published

    Is exercise effective in promoting mental well-being in older age? A systematic review.

    Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Aug 2010, In: Aging and Mental Health. 14, 6, p. 652-669

    Research output: Contribution to journal › Article › peer-review

51. Published

    Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

    Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417

    Research output: Contribution to journal › Article › peer-review

52. Published

    A parenting programme for children at risk of developing conduct disorder: A cost-effectiveness analysis

    Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 1 May 2007.

    Research output: Contribution to conference › Paper

53. Published

    Economic evaluations during early (Phase II) drug development: A role for clinical trial simulations.

    Hughes, D., Hughes, D. A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 11, p. 1069-1077

    Research output: Contribution to journal › Article › peer-review

54. Published

    Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments – piloting a discrete choice experiment

    Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Mar 2008

    Research output: Non-textual form › Web publication/site

55. Published

    Drug compliance and pharmaceconomics

    Hughes, D. & Hughes, D. A., 1 Dec 2003.

    Research output: Contribution to conference › Paper

56. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Parathyroid hormone (Preotact)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

57. Published

    Methodological issues in the literature on costs of non-compliance in chronic diseases

    Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008.

    Research output: Contribution to conference › Paper

58. Published

    Economic evaluation during early (phase II) trials

    Hughes, D. & Hughes, D. A., 1 Nov 2002.

    Research output: Contribution to conference › Paper

59. Published

    Impact of the abolition of the prescription charge in Wales

    Hughes, D. & Hughes, D. A., 1 Nov 2008.

    Research output: Contribution to conference › Paper

60. Published

    A prototype agent-based model of antimalarial drug compliance

    Hughes, D., McKean, J., Rahlf, S., Shorter, H., Barnish, G., Paton, R., McBurney, P., Hughes, D. A. & Hastings, I., 1 Aug 2007.

    Research output: Contribution to conference › Paper

61. Published

    Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Nov 2003, In: Value in Health. 6, 6, p. 749

    Research output: Contribution to journal › Article › peer-review

62. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conference › Paper

63. Published

    Abolition of prescription copayments in Wales: an observational study on dispensing rates.

    Hughes, D., Cohen, D., Alam, M. F., Dunstan, F. D., Myles, S., Hughes, D. A. & Routledge, P. A., 1 Aug 2010, In: Value in Health. 13, 5, p. 675-680

    Research output: Contribution to journal › Article › peer-review

64. Published

    Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations.

    Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Nov 2007, In: Value in Health. 10, 6, p. 498-509

    Research output: Contribution to journal › Article › peer-review

65. Published

    Effects of the abolition of prescription charges in Wales: A preliminary analysis

    Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

    Research output: Contribution to conference › Paper

66. Published

    Pharmacogenetic tests: the need for a level playing field

    Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4

    Research output: Contribution to journal › Article › peer-review

67. Published

    What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?

    Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.

    Research output: Contribution to conference › Paper

68. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-experienced patients.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

69. Published

    Adverse drug reactions in economic evaluations

    Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A109

    Research output: Contribution to journal › Article › peer-review

70. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Tenofovir disoproxil fumarate (Viread) for the treatment of hepatitis B.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

71. Published

    The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies.

    Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

    Research output: Book/Report › Commissioned report

72. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Clofarabine (Evoltra)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

73. Published

    Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.

    Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25

    Research output: Contribution to journal › Letter › peer-review

74. Published

    Health utilities and costs for neuromyelitis optica spectrum disorder

    Hughes, D., Bourke, S., Jones, A., Bhatt, R., Huda, S., Mutch, K. & Jacob, A., 2022, In: Orphanet Journal of Rare Diseases. 17, 11 p., 159.

    Research output: Contribution to journal › Article › peer-review

75. Published

    Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study

    Hughes, D. & Poletti-Hughes, J., 21 Oct 2016, In: PLoS ONE. 11, 10, e0164681.

    Research output: Contribution to journal › Article › peer-review

76. Published

    Economics of pharmacogenetic guided treatments: Underwhelming or overstated?

    Hughes, D., May 2018, In: Clinical Pharmacology and Therapeutics. 103, 5, p. 749-751

    Research output: Contribution to journal › Article › peer-review

77. Published

    Rare disease prevention and treatment: The need for a level playing field

    Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247

    Research output: Contribution to journal › Article › peer-review

78. Published

    Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam

    Hughes, D., Nov 2020, In: British Journal of Pharmacology. 177, 21, p. 4975-4989 15 p.

    Research output: Contribution to journal › Article › peer-review

79. Published

    Management of Patients Symptomatically Unresponsive to Levothyroxine: Natural Desiccated Thyroid Extract or the Combination of Levothyroxine and Liothyronine? A Research Priority

    Hughes, D., Livingston, M. & Heald, A., Sept 2020, In: Experimental and Clinical Endocrinology & Diabetes . 128, 9, p. 596-598

    Research output: Contribution to journal › Letter › peer-review

80. Published

    Liothyronine for hypothyroidism: A candidate for disinvestment or in need of further research? A value of information analysis

    Hughes, D., Skiadas, K., Fitzsimmons, D., Anderson, P. & Heald, A., 3 Dec 2021, In: BMJ Open. 11, 12, e051702.

    Research output: Contribution to journal › Article › peer-review

81. Published

    Medication adherence – key considerations for clinical pharmacologists

    Hughes, D., Apr 2020, In: British Journal of Clinical Pharmacology. 86, 4, p. 628-629 2 p.

    Research output: Contribution to journal › Editorial › peer-review

82. E-pub ahead of print

    We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment

    Hughes, D., 27 Sept 2023, (E-pub ahead of print) In: Health Economics, Policy and Law.

    Research output: Contribution to journal › Article › peer-review

83. Published

    Medicines Shortages in the United Kingdom

    Hughes, D., Oct 2019, In: Clinical Pharmacology and Therapeutics. 106, 4, p. 712

    Research output: Contribution to journal › Letter › peer-review

84. Published

    Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis

    Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. 415-424

    Research output: Contribution to journal › Article › peer-review

85. Published

    Impact of relaxing Covid-19 social distancing measures on rural North Wales: a simulation analysis

    Hughes, R. P. & Hughes, D., 14 Dec 2020, In: Frontiers in Public Health. 8, 562473.

    Research output: Contribution to journal › Article › peer-review

86. Published

    The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial

    Jenkinson, M. D., Javadpour, M., Haylock, B. J., Young, B., Gillard, H., Vinten, J., Bulbeck, H., Das, K., Farrell, M., Looby, S., Hickey, H., Preusser, M., Mallucci, C. L., Hughes, D., Gamble, C. & Weber, D. C., 14 Nov 2015, In: Trials. 16

    Research output: Contribution to journal › Article › peer-review

87. Published

    Letter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma

    Jenkinson, M., Weber, D., Haylock, B., Sherratt, F., Young, B., Weller, M., Bulbeck, H., Culeddu, G., Hughes, D., Brain, A., Das, K., Preusser, M., Francis, P. & Gamble, C., 17 Aug 2018, In: Journal of Neurology, Neurosurgery and Psychiatry.

    Research output: Contribution to journal › Letter › peer-review

88. Published

    Evidence to support inclusion of pharmacogenetic biomarkers in randomised controlled trials

    Johnson, D., Jorgensen, A., Hughes, D. & Pirmohamed, M., 1 Sept 2019, In: Journal of Personalized Medicine. 9, 3, 19 p., 42.

    Research output: Contribution to journal › Review article › peer-review

89. Published

    A randomised, patient-assessor blinded, sham-controlled trial of external noninvasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial): study protocol for a randomised controlled trial

    Johnson, S., Goebel, A., Richey, R., Holmes, E. & Hughes, D., 6 Dec 2016, In: Trials. 17, 574.

    Research output: Contribution to journal › Article › peer-review

90. Published

    Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial

    Johnson, S., Marshall, A., Hughes, D., Holmes, E., Henrich, F., Nurmikko, T., Sharma, M., Frank, B., Bassett, P., Marshall, A. & Goebel, A., 6 Nov 2021, In: Journal of Translational Medicine. 19, 1, 458.

    Research output: Contribution to journal › Article › peer-review

91. Published

    A “Bundle of Care” to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study

    Jorgensen, AL., Waitt, C., Orrell, C., Cheng-Hock, T., Sekaggya-Wiltshire, C., Hughes, D., Allen, E., Okello, E., Tatz, G., Culeddu, G., Asiimwe, I. G., Semakula, J. R., Mouton, J. P., Cohen, K., Blockman, M., Lamorde, M. & Pirmohamed, M., 19 Jul 2023, In: Journal of Medical Internet Research. 12, e46710.

    Research output: Contribution to journal › Article › peer-review

92. Published

    Decision analytic modelling methods for the assessing the effectiveness of treatment sequences for clinical and economic decision making: a methodological review

    Lewis, R., Hughes, D. & Wilkinson, C., 30 Nov 2017, In: Value in Health. 20, 9, p. A748 1 p.

    Research output: Contribution to journal › Article › peer-review

93. Published

    Quantitative evidence synthesis methods for the assessment of the effectiveness of treatment sequences for clinical and economic decision-making: a review and taxonomy of simplifying assumptions

    Lewis, R., Hughes, D., Sutton, AJ. & Wilkinson, C., Jan 2021, In: PharmacoEconomics. 39, 1, p. 25-61 37 p.

    Research output: Contribution to journal › Article › peer-review

94. Published

    Nurse-led vs. conventional physician-led follow-up for patients with cancer: systematic review

    Lewis, R., Neal, R. D., Williams, N. H., France, B., Wilkinson, C. E., Hendry, M., Russell, D., Russell, I., Hughes, D., Stuart, N. S. & Weller, D., 1 Apr 2009, In: Journal of Advanced Nursing. 65, 4, p. 706-723

    Research output: Contribution to journal › Article › peer-review

95. Published

    Patients' and healthcare professionals' views of cancer follow-up: systematic review

    Lewis, R., Neal, R. D., Hendry, M., France, B., Williams, N. H., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., Jul 2009, In: British Journal of General Practice. 59, 564, p. e248-e259

    Research output: Contribution to journal › Article › peer-review

96. Published

    Follow-up of cancer in primary care versus secondary care: systematic review

    Lewis, R. A., Neal, R. D., Williams, N. H., France, B., Hendry, M., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., 1 Jul 2009, In: British Journal of General Practice. 59, 564, p. e234-e247

    Research output: Contribution to journal › Article › peer-review

97. Published

    A Systematic Review of Economic Evaluations of Advanced Therapy Medicinal Products

    Lloyd Williams, H. & Hughes, D., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2428-2443 16 p.

    Research output: Contribution to journal › Review article › peer-review

98. Published

    Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria

    Lotsch, F., Auer-Hackenberg, L., Groger, M., Rehman, K., Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., de Geest, S., Dobbels, F., Vrijens, B., Kardas, P., Hughes, D. & Ramharter, M., May 2015, In: Wiener klinische Wochenschrift. 127, 9-10, p. 379-384

    Research output: Contribution to journal › Article › peer-review

99. Published

    Pharmacogenomics spotlight commentary: From the United Kingdom to global populations

    Magavern, E. F., Daly, A. K., Gilchrist, A. & Hughes, D., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4546-4548 3 p., 14917.

    Research output: Contribution to journal › Comment/debate › peer-review

100. Published

     Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT

     Mallucci, C. L., Jenkinson, M., Conroy, E. J., Hartley, J. C., Brown, M., Moitt, T., Dalton, J., Kearns, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 2 Apr 2020, In: Health Technology Assessment. 24, 17, 114 p.

     Research output: Contribution to journal › Article › peer-review

101. Published

     Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multi-centre, single-blinded, randomised trial and economic evaluation

     Mallucci, C. L., Jenkinson, M. D., Conroy, E. J., Hartley, J. C., Brown, M., Dalton, J., Kearns, T., Moitt, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 26 Oct 2019, In: The Lancet. 394, 10208, p. 1530-1539 10 p.

     Research output: Contribution to journal › Article › peer-review

102. Published

     Extended-release pharmacotherapy for opioid use disorder (EXPO): protocol for an open-label randomised controlled trial of the effectiveness and cost-effectiveness of injectable buprenorphine versus sublingual tablet buprenorphine and oral liquid methadone

     Marsden, J., Kelleher, M., Hoare, Z., Hughes, D., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Scott, G., Turner, S., Vanderwaal, R., Wareham, A., Gilvarry, E. & Mitcheson, L., 19 Aug 2022, In: Trials. 23, 1, 697.

     Research output: Contribution to journal › Article › peer-review

103. Published

     Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial

     Marsden, J., Kelleher, M., Gilvarry, E., Mitcheson, L., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hardy, W., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Vanderwaal, R., Wareham, A., Hughes, D. & Hoare, Z., Dec 2023, In: eClinicalMedicine. 66, 23 p., 102331.

     Research output: Contribution to journal › Article › peer-review

104. Published

     The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

     Marson, A., Burnside, G., Appleton, R., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1375-1386

     Research output: Contribution to journal › Article › peer-review

105. Published

     The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

     Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1363-1374

     Research output: Contribution to journal › Article › peer-review

106. Published

     Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs

     Marson, A. G., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P. R., Baker, G., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., Dec 2021, In: Health Technology Assessment. 25, 75, 162 p.

     Research output: Contribution to journal › Article › peer-review

107. Published

     Cost-effectiveness of home versus hospital management of children at onset of Type 1 Diabetes: The DECIDE randomised controlled trial

     McCarroll, Z., Townson, J., Pickles, T., Gregory, J. W., Playle, R., Robling, M. & Hughes, D., 19 May 2021, In: BMJ Open. 11, 5, e043523.

     Research output: Contribution to journal › Article › peer-review

108. Published

     A Fully Integrated Real-Time Detection, Diagnosis, and Control of Community Diarrheal Disease Clusters and Outbreaks (the INTEGRATE Project): Protocol for an Enhanced Surveillance System

     McIntyre, K. M., Bolton, F. J., Christley, R. M., Cleary, P., Deja, E., Durie, A. E., Diggle, P. J., Hughes, D., de Lusignan, S., Orton, L., Radford, A. D., Elliot, A., Smith, G. E., Snape, D. A., Stanistreet, D., Vivancos, R., Winstanley, C. & O'Brien, S. J., 26 Sept 2019, In: JMIR Research Protocols. 8, 9, p. e13941 10 p., e13941.

     Research output: Contribution to journal › Article › peer-review

109. Published

     Advanced therapy medicinal products: a comprehensive overview for pharmacy professionals

     McKenzie, C. A., Chappel, J., Guy, R. H., Hawksworth, G., Hughes, D. & Black, A., 12 Aug 2022, In: Pharmaceutical Journal.

     Research output: Contribution to journal › Article › peer-review

110. E-pub ahead of print

     Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study

     Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L., 9 Apr 2024, (E-pub ahead of print) In: ACR Open Rheumatology.

     Research output: Contribution to journal › Article › peer-review

111. Published

     The experiences and perspectives of people with gout on urate self-monitoring

     Michael, T. J. F., Chan, J. S., Hughes, S., Wright, D. F. B., Coleshill, M. J., Hughes, D., Day, R. O., Aslani, P. & Stocker, S. L., Jun 2024, In: Health Expectations. 27, 3, 9 p., e14071.

     Research output: Contribution to journal › Article › peer-review

112. Published

     Economic Studies in Motor Neurone Disease: A Systematic Methodological Review

     Moore, A., Young, C. A. & Hughes, D., Apr 2017, In: Pharmacoeconomics. 35, 4, p. 397-413

     Research output: Contribution to journal › Article › peer-review

113. Published

     Health utilities and costs for Motor Neurone Disease

     Moore, A., Young, C. A. & Hughes, D., Nov 2019, In: Value in Health. 22, 11, p. 1257-1265

     Research output: Contribution to journal › Article › peer-review

114. Published

     Mapping ALSFRS-R and ALSUI to EQ-5D in patients with motor neurone disease

     Moore, A., Young, C. A. & Hughes, D., Nov 2018, In: Value in Health. 21, 11, p. 1322-1329

     Research output: Contribution to journal › Article › peer-review

115. Published

     Predictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey

     Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Mar 2015, In: Value in Health. 18, 2, p. 206-216

     Research output: Contribution to journal › Article › peer-review

116. Published

     ‘Seizure First Aid Training’ for people with epilepsy who attend emergency departments, and their family and friends: study protocol for intervention development and a pilot randomised controlled trial

     Noble, A. J., Marson, A. G., Tudur-Smith, C., Morgan, M., Hughes, D., Goodacre, S. & Ridsdale, L., 24 Jul 2015, In: BMJ Open. 5, 7

     Research output: Contribution to journal › Article › peer-review

117. Published

     Seizure First Aid Training For people with Epilepsy (SAFE) frequently attending emergency departments and their significant others: results of a UK multi-centre randomised controlled pilot trial

     Noble, A. J., Snape, D., Nevitt, S., Holmes, E., Morgan, M., Smith, C. T., Hughes, D., Buchanan, M., McVicar, J., MacCallum, E., Goodacre, S., Rinsdale, L. & Marson, A. G., 16 Apr 2020, In: BMJ Open. 10, 4, e035516.

     Research output: Contribution to journal › Article › peer-review

118. Published

     Developing patient-centred, feasible alternative care for adult emergency department users with epilepsy: Protocol for the mixed-methods observational ‘Collaborate’ project.

     Noble, A. J., Mathieson, A., Ridsdale, L., Holmes, E., Morgan, M., McKinlay, A., Dickson, J., Jackson, M., Hughes, D., Goodacre, S. & Marson, A. G., 2 Nov 2019, In: BMJ Open. 9, 11, e031696.

     Research output: Contribution to journal › Article › peer-review

119. Accepted/In press

     Developing feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed methods study

     Noble, A. J., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Morris, B., Hughes, D., Marson, T. & Holmes, E., 6 Jun 2023, (Accepted/In press) In: Health Services and Delivery Research (HS&DR).

     Research output: Contribution to journal › Article › peer-review

120. Published

     Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project

     Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 17-27 11 p.

     Research output: Contribution to journal › Article › peer-review

121. Published

     Adverse drug reactions, multimorbidity and polypharmacy: A prospective analysis of one month of medical admissions

     Osanlou, R., Walker, L., Hughes, D., Burnside, G. & Pirmohamed, M., 4 Jul 2022, In: BMJ Open. 12, 7, e055551.

     Research output: Contribution to journal › Article › peer-review

122. Published

     The Development of a Consistent Europe-Wide Approach to Investigating the Economic Impact of Myalgic Encephalomyelitis (ME/CFS): A Report from the European Network on ME/CFS (EUROMENE)

     Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 7 Apr 2020, In: Healthcare. 8, 2, 88.

     Research output: Contribution to journal › Article › peer-review

123. Published

     The role of prevention in reducing the economic impact of ME/CFS in Europe: A report from the socioeconomics working group of the European Network on ME/CFS (EUROMENE).

     Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 16 Apr 2021, In: Medicina. 57, 4, 388.

     Research output: Contribution to journal › Article › peer-review

124. Published

     A Literature Review of GP Knowledge and Understanding of ME/CFS: A Report from the Socioeconomics Working Group of the European Network on ME/CFS (EUROMENE)

     Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., Jan 2021, In: Medicina. 57, 1, 17 p., 7.

     Research output: Contribution to journal › Article › peer-review

125. Published

     Costs of orphan medicinal products: longitudinal analysis of expenditure in Wales

     Pijeira Perez, Y., Wood, E. & Hughes, D., 1 Nov 2023, In: Orphanet Journal of Rare Diseases. 18, 1, 342.

     Research output: Contribution to journal › Article › peer-review

126. Published

     Cost effectiveness of pharmacogenetic screening prior to initiation of carbamazepine treatment for epilepsy

     Plumpton, C. O., Yip, V., Alfirevic, A., Marson, A., Pirmohamed, M. & Hughes, D., Nov 2013, In: Value in Health. 16, 7, p. A624-A624

     Research output: Contribution to journal › Article › peer-review

127. Published

     Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout

     Plumpton, C., Alfirevic, A., Pirmohamed, M. & Hughes, D., 1 Oct 2017, In: Rheumatology. 56, 10, p. 1729-1739

     Research output: Contribution to journal › Article › peer-review

128. Published

     Cost-effectiveness of HLA-B*15:02 screening in Malaysia

     Plumpton, C. & Hughes, D., Oct 2017, In: British Journal of Dermatology. 177, 4, p. 904-905

     Research output: Contribution to journal › Comment/debate

129. Published

     Cost-effectiveness of screening for HLA-A*31:01 prior to initiation of carbamazepine in epilepsy

     Plumpton, C., Yip, V. L. M., Alfirevic, A., Marson, A. G., Pirmohamed, M. & Hughes, D., Apr 2015, In: Epilepsia.

     Research output: Contribution to journal › Article › peer-review

130. Published

     Cost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework

     Plumpton, C., Pirmohamed, M. & Hughes, D., Jun 2019, In: Clinical Pharmacology and Therapeutics. 105, 6, p. 1429-1438

     Research output: Contribution to journal › Article › peer-review

131. Published

     A systematic review of economic evaluations of pharmacogenetic testing for prevention of adverse drug reactions

     Plumpton, C. O., Roberts, D., Pirmohamed, M. & Hughes, D. A., Aug 2016, In: Pharmacoeconomics. 34, 8, p. 771-793

     Research output: Contribution to journal › Article › peer-review

132. Published

     CARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial

     Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Feb 2019, In: Trials. 20, 1, 16 p., 105.

     Research output: Contribution to journal › Article › peer-review

133. Published

     Carer administration of as-needed sub-cutaneous medication for breakthrough symptoms in people dying at home: the CARiAD feasibility RCT

     Poolman, M., Roberts, J., Wright, S., Hendry, A., Goulden, N., Holmes, E., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., O'Connor, J., Foster, B., Reymond, L., Healy, S., Lewis, P., Wee, B., Johnstone, R. P., Roberts, R., Parkinson, A., Roberts, S. & Wilkinson, C., 2 Jun 2020, In: Health Technology Assessment. 24, 25, 150 p.

     Research output: Contribution to journal › Article › peer-review

134. Published

     Pharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery

     Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Jul 2015, In: British Journal of Clinical Pharmacology. 80, 5, p. 1149-1159

     Research output: Contribution to journal › Article › peer-review

135. Published

     Using Routinely Recorded Data in the UK to Assess Outcomes in a Randomised Controlled Trial: The Trials of Access

     Powell, G., Bonnett, L., Smith, C. T., Hughes, D., Williamson, P. & Marson, A., 23 Aug 2017, In: Trials. 18, 11 p., 389.

     Research output: Contribution to journal › Article › peer-review

136. Published

     Using Routinely Recorded Data in a UK RCT: A Comparison to Standard Prospective Data Collection Methods

     Powell, G., Bonnett, L., Tudor-Smith, C., Hughes, D., Williamson, P. R. & Marson, A. G., 5 Jul 2021, In: Trials. 22, 1, 429.

     Research output: Contribution to journal › Article › peer-review

137. Published

     Do guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review

     Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Jul 2018, In: Thorax. 73, 7, p. 670-673

     Research output: Contribution to journal › Letter › peer-review

138. Published

     Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT

     Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D., McKay, A., Rosala_Hanna, A., Williamson, P. R., Hardwick, B., Hickey, H., Rainford, N., Kolamunnage-Dona, R., Culeddu, G., Plumpton, C., Wood, E., Compeyrot-Lacassagne, S., Woo, P., Eldesten, C. & Beresford, M. W., 10 Apr 2019, In: Health Technology Assessment. 23, 15, p. 1-174 174 p.

     Research output: Contribution to journal › Article › peer-review

139. Published

     Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis

     Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., Hardwick, B., Hickey, H., Hughes, D., Woo, P., Benton, D., Edelsten, C. & Beresford, M. W., 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1637-1646

     Research output: Contribution to journal › Article › peer-review

140. Published

     Development of a Database of Instruments for Resource-Use Measurement: Purpose, Feasibility, and Design

     DIRUM Team, 1 Jul 2012, In: Value in Health. 15, 5, p. 650-655

     Research output: Contribution to journal › Article › peer-review

141. Published

     Methods for the collection of resource use data within clinical trials: A systematic review of studies funded by the UK Health Technology Assessment Program

     Ridyard, C. H. & Hughes, D., 1 Dec 2010, In: Value in Health. 13, 8, p. 867-872

     Research output: Contribution to journal › Article › peer-review

142. Published

     A Systematic Review of Patient Preferences for Subcutaneous Medications

     Ridyard, C., Dawoud, D. & Hughes, D., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

143. Published

     Use Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients

     Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A580

     Research output: Contribution to journal › Article › peer-review

144. Published

     Continuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis

     Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A582

     Research output: Contribution to journal › Article › peer-review

145. Published

     Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

     Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A590

     Research output: Contribution to journal › Article › peer-review

146. Published

     Patient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations

     Ridyard, C. & Hughes, D., 7 May 2017, p. P141. 1 p.

     Research output: Contribution to conference › Poster › peer-review

147. Published

     A systematic review of patients' perspectives on the subcutaneous route of medication administration

     Ridyard, C., Dawoud, D. M., Tuersley, L. V. & Hughes, D., Aug 2016, In: Patient: Patient–Centered Outcomes Research. 9, 4, p. 281-292

     Research output: Contribution to journal › Article › peer-review

148. Published

     Taxonomy for methods of resource use measurement

     DIRUM Team, 23 Jan 2015, In: Health Economics. 24, 3, p. 372-378

     Research output: Contribution to journal › Letter › peer-review

149. Published

     Cost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial

     Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Sept 2017, In: Frontiers in Pharmacology. 8, 644.

     Research output: Contribution to journal › Article › peer-review

150. Published

     Review of resource-use measures in UK economic evaluations

     Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (eds.). University of Kent, Canterbury, p. 22-31 10 p.

     Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

151. Published

     Review of the use of resource use instruments based on patient recall in relation to other methods of resource use estimation

     Ridyard, C. & Hughes, D., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

152. Published

     Review of the Use of Resource Use Instruments Based on Patient Recall in Relation to Other Methods of Cost Estimation

     Ridyard, C. & Hughes, D., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

153. Published

     Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

     Ridyard, C., Blair, J. & Hughes, D., Nov 2017, In: Value in Health. 20, 9, p. A481 - A482

     Research output: Contribution to journal › Article › peer-review

154. Published

     What really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK

     Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Jun 2019, In: Epilepsy and Behavior. 95, p. 181-191

     Research output: Contribution to journal › Article › peer-review

155. Published

     Enhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.

     Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Jan 2010.

     Research output: Contribution to conference › Paper

156. Published

     Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial.

     Russell, I. T., Slegg, G. P., Roberts, S. H., Bedson, E., Hughes, D., Lloyd, K., Moat, S., Pirmohamed, M., Slegg, G., Tranter, R., Whitaker, R., Wilkinson, C. & Russell, I., 15 Nov 2007, In: BMC Psychiatry. 7, 1, p. 65

     Research output: Contribution to journal › Article › peer-review

157. Published

     Supply-side cost-effectiveness thresholds: questions for evidence-based policy

     Sampson, C., Zamora, B., Watson, S., Cairns, J., Chalkidou, K., Cubi-Molla, P., Devlin, N., García-Lorenzo, B., Hughes, D., Leech, A. & Towse, A., Sept 2022, In: Applied Health Economics and Health Policy. 20, 5, p. 651-667

     Research output: Contribution to journal › Article › peer-review

158. Published

     Opportunity costs and local health service spending decisions: a qualitative study from Wales

     Schaffer, S. K., Sussex, J., Hughes, D. & Devlin, N., 25 Mar 2016, In: BMC Health Services Research. 16, 103

     Research output: Contribution to journal › Article › peer-review

159. Published

     Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone.

     Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, G., Watkins, W. A. & Ward, S., 1 Mar 2006, In: British Journal of Clinical Pharmacology. 61, 3, p. 289-300

     Research output: Contribution to journal › Article › peer-review

160. Published

     Clinical interventions to improve adherence to urate-lowering therapy in patients with gout: a systematic review

     Sinnappah, K. A., Stocker, S. L., Chan, J. S., Hughes, D. A. & Wright, D. F. B., 25 Jun 2022, In: International Journal of Pharmacy Practice. 30, 3, p. 215-225 11 p.

     Research output: Contribution to journal › Article › peer-review

161. E-pub ahead of print

     A framework for understanding sources of bias in medication adherence research

     Sinnappah, K. A., Hughes, D., Stocker, S. L., Vrijens, B., Aronson, J. K. & Wright, D. F. B., 26 Jul 2023, (E-pub ahead of print) In: British Journal of Clinical Pharmacology.

     Research output: Contribution to journal › Article › peer-review

162. Published

     Cost and clinical consequence of antibiotic non-adherence in acute exacerbations of chronic bronchitis.

     Sorensen, S. V., Baker, T., Fleurence, R., Dixon, J., Roberts, C., Haider, S. & Hughes, D., 1 Aug 2009, In: International Journal of Tuberculosis and Lung Disease. 13, 8, p. 945-954

     Research output: Contribution to journal › Article › peer-review

163. Published

     Have infection control and prevention measures resulted in any adverse outcomes for care home and domiciliary care residents and staff? Report number: RR_00018 (November 2021)

     Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 1 Nov 2021, 36 p.

     Research output: Book/Report › Other report › peer-review

164. Published

     The costs and cost-effectiveness of different service models of palliatice care, focusing on end of life care: A rapid review

     Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Gillen, E., Noyes, J., Fitzsimmons, D., Lewis, R., Cooper, A., Hughes, D., Edwards, R. T. & Edwards, A., 7 Mar 2024, MedRxiv, 118 p.

     Research output: Working paper › Preprint

165. Published

     RES00038. Wales COVID-19 Evidence Centre. A rapid evidence summary of the cost impact of Long COVID on employment and caring responsibilities

     Spencer, L., Hendry, A., Davies, J., Pisavadia, K., Hughes, D. & Edwards, R. T., May 2022, Welsh Government. 18 p.

     Research output: Book/Report › Other report

166. Published

     What is the effectiveness and cost-effectiveness of interventions in reducing the harms for children and young people who have been exposed to domestic violence or abuse: a rapid review.

     Spencer, L., Hendry, A., Makanjuola, A., Pisavadia, K., Davies, J., Albustami, M., Anthony, B., Wilkinson, C., Fitzsimmons, D., Hughes, D., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 10 May 2023, 79 p.

     Research output: Book/Report › Commissioned report

167. Published

     What innovations can address inequalities experienced by women and girls due to the COVID-19 pandemic across the different areas of life/domains: work, health, living standards, personal security, participation and education? Report number – RR00027 (January 2022). Gender Inequalities: COVID-19 initiatives

     Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Pisavadia, K., Davies, J., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 15 Jan 2022, Health and Care Research Wales.

     Research output: Book/Report › Commissioned report › peer-review

168. Published

     What interventions or best practice are there to support people with Long COVID, or similar post-viral conditions or conditions characterised by fatigue, to return to normal activities: a rapid review

     Spencer, L., Hendry, A., Makanjuola, A., Anthony, B., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 28 Jan 2023, 34 p. (MedRxiv).

     Research output: Working paper › Preprint

169. Published

     What is the long-term impact of COVID-19 on the Health-Related Quality of Life of individuals with mild symptoms (or non-hospitalised): A rapid review

     Spencer, L., Hendry, A., Makanjuola, A., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 9 Sept 2022, Health and Care Research Wales, 47 p.

     Research output: Working paper › Preprint

170. Published

     RES00019. Wales COVID-19 Evidence Centre. A rapid evidence summary indicating the evidence of the inverse care law in social care in Wales and has this been exacerbated by the COVID-19 pandemic?

     Spencer, L., Hendry, A., Makanjuola, A., Hughes, D., Wilkinson, C., Pisavadia, K., Davies, J., Fitzsimmons, D. & Edwards, R. T., Feb 2022, Welsh Government. 33 p.

     Research output: Book/Report › Other report

171. Published

     Value of improving patient safety: Health-economic considerations for Rapid Response Systems – a Rapid Review of the Literature and Expert Round Table

     Subbe, C., Hughes, D., Lewis, S., Holmes, E., Kalkman, C. J., So, R. K., Tranka, S. & Welch, J., 17 Apr 2023, In: BMJ Open. 13, 4, e065819.

     Research output: Contribution to journal › Article › peer-review

172. Published

     Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care

     Swift, B., Jain, L., White, C., Chandrasekaran, V., Bhandari, A., Hughes, D. & Jadhav, P., Sept 2018, In: Clinical and Translational Science. 11, 5, p. 450-460 11 p.

     Research output: Contribution to journal › Article › peer-review

173. Published

     Core items for a standardized resource-use measure (ISRUM): expert Delphi consensus survey

     Thom, J., Brookes, S. T., Ridyard, C., Riley, R., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., Jun 2018, In: Value in Health. 21, 6, p. 640-649

     Research output: Contribution to journal › Article › peer-review

174. Published

     Resource-Use Measurement Based on Patient Recall: Issues and Challenges for Economic Evaluation

     Thorn, J. C., Coast, J., Cohen, D., Hollingworth, W., Knapp, M., Noble, S. M., Ridyard, C. H., Wordsworth, S. & Hughes, D., 1 Jun 2013, In: Applied Health Economics and Health Policy. 11, 3, p. 155-161

     Research output: Contribution to journal › Article › peer-review

175. Published

     Identification Of Items For A Standardised Resource-Use Measure: Review Of Current Instruments

     Thorn, J. C., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S. & Hollingworth, W., Nov 2015.

     Research output: Contribution to conference › Paper › peer-review

176. Published

     Core items for a standardised resource-use measure (ISRUM):expert Delphi consensus survey

     Thorn, J., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., 7 May 2017, p. P265. 1 p.

     Research output: Contribution to conference › Poster › peer-review

177. Published

     Health economics analysis plans: the current state of play

     Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 7 May 2017, p. P144. 1 p.

     Research output: Contribution to conference › Poster › peer-review

178. Published

     Health Economics Analysis Plans: Where Are We Now?

     Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 3 Nov 2016, p. A397. 1 p.

     Research output: Contribution to conference › Poster › peer-review

179. Published

     Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey

     Thorn, J., Davies, C. F., Brookes, S., Noble, S., Dritsaki, M., Gray, E., Hughes, D., Mihaylova, B., Petrou, S., Ridyard, C., Sach, T., Wilson, E., Wordsworth, S. & Hollingworth, W., 1 Apr 2021, In: Value in Health. 24, 4, p. 539-547 9 p.

     Research output: Contribution to journal › Article › peer-review

180. Published

     Appropriate design and reporting of superiority, equivalence and non-inferiority clinical trials incorporating a benefit risk assessment: the BRAINS study including expert workshop

     Totton, N., Julious, S., Coates, E., Hughes, D., Cook, J., Biggs, K., Hewitt, C., Day, S. & Cooke, A., Oct 2023, In: Health Technology Assessment. 27, 20, 86 p.

     Research output: Contribution to journal › Article › peer-review

181. Published

     Utilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project

     Totton, N., Julious, S., Hughes, D., Cook, J., Biggs, K., Coates, L., Cook, A., Hewitt, C. & Day, S., 19 Jan 2021, In: Trials. 22, 68.

     Research output: Contribution to journal › Article › peer-review

182. Published

     A proposal for using benefit-risk methods to improve the prominence of adverse event results when reporting trials

     Totton, N., Waddingham, E., Owen, R., Julious, S., Hughes, D. & Cook, J., 22 Jun 2024, In: Trials. 25, 409.

     Research output: Contribution to journal › Article › peer-review

183. Published

     Acceptability of generic versus innovator oral medicines: not only a matter of taste

     Tuleu, C., Hughes, D., Clapham, D., Vallet, T. & Ruiz, F., Feb 2021, In: Drug Discovery Today. 26, 2, p. 329-343

     Research output: Contribution to journal › Article › peer-review

184. Published

     New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes

     Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., May 2018, In: Pharmacoeconomics. 36, 5, p. 613-624 12 p.

     Research output: Contribution to journal › Article › peer-review

185. Published

     Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden

     Verhoef, T. I., Redekop, W. K., Langenskiold, S., Kamali, F., Wadelius, M., Burnside, G., Maitland-van der Zee, A. H., Hughes, D. & Pirmohamed, M., Oct 2016, In: The Pharmacogenomics Journal. 16, p. 478–484

     Research output: Contribution to journal › Article › peer-review

186. Published

     Trends and influences on use of antidiabetic drugs in England, 1992-2003.

     Walley, T., Hughes, D. & Kendall, H., 1 Nov 2005, In: Pharmacoepidemiology and Drug Safety. 14, 11, p. 769-773

     Research output: Contribution to journal › Article › peer-review

187. Published

     Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation

     Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. G. & Williamson, P., 1 May 2021, In: The Lancet Rheumatology. 3, 5, p. e347-e356

     Research output: Contribution to journal › Article › peer-review

188. Published

     Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT

     Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Bostock, J., Hay, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. & Williamson, P. R., Apr 2021, In: Health Technology Assessment. 25, 24, 86 p.

     Research output: Contribution to journal › Article › peer-review

189. Published

     Carer-administration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARIAD)

     Wilkinson, C., Poolman, M., Roberts, J., Wee, B., Hiscock, J., Hughes, D., Nelson, A., Perkins, P., Johnstone, R. P., Reymond, E., Foster, B., O'Connor, J., Jones, S., Hoare, Z., Roberts, R., Byrne, A., Healy, S. & Lewis, P., 1 Sept 2017.

     Research output: Contribution to conference › Poster › peer-review

190. Published

     Lessons learnt from a discontinued randomised controlled trial: Adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC)

     Williams, N., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Jul 2018, In: Trials. 19, 408.

     Research output: Contribution to journal › Article › peer-review

191. Published

     Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica

     Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Oct 2017, In: Health Technology Assessment. 21, 60, p. 1-180 180 p.

     Research output: Contribution to journal › Article › peer-review

192. Published

     Effectiveness of out-patient based acute heart failure care: A pilot randomised controlled trial

     Wong, K. Y. K., Hughes, D., Debski, M., Latt, N., Assaf, O., Abdelrahman, A., Taylor, R., Allgar, V., McNeill, L., Howard, S., Wong, S. Y. S., Jones, R., Cassidy, C. J., Seed, A., Galasko, G., Clark, A., Davis, G. K., Montasem, A., Lang, C. C., Kalra, P. R., Campbell, R., Lip, G. Y. H. & Cleland, J. G. F., Oct 2023, In: Acta Cardiologica. 78, 7, p. 828-837 10 p.

     Research output: Contribution to journal › Article › peer-review

193. Published

     The new and non-transparent Cancer Drugs Fund

     Wood, E. & Hughes, D., Jan 2020, In: PharmacoEconomics. 38, 1, p. 1-4

     Research output: Contribution to journal › Article › peer-review

194. Published

     Medication adherence research comes of age

     Wright, D. F. B., Sinnappah, K. A. & Hughes, D., Jul 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 1914-1917

     Research output: Contribution to journal › Editorial › peer-review

195. Published

     Improving Medication Adherence Research Reporting: European Society for Patient Adherence, Compliance and Persistence Medication Adherence Reporting Guideline

     de Geest, S., Zullig, L., Dunbar-Jacobs, J., Hughes, D., Wilson, I. & Vrijens, B., Jun 2019, In: Journal of Cardiovascular Nursing. 34, 3, p. 199-200

     Research output: Contribution to journal › Editorial › peer-review

196. Published

     Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

     de Geest, S., Zullig, L. L., Dunbar-Jacob, J., Hughes, D., Wilson, I. & Vrijens, B., 1 Apr 2019, In: European Journal of Cardiovascular Nursing. 18, 4, p. 258-259 2 p.

     Research output: Contribution to journal › Editorial › peer-review

197. E-pub ahead of print

     Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial

     SuMMiT-D Collaborative Group , 25 Jan 2024, (E-pub ahead of print) In: Pilot and Feasibility Studies. 10, 1, 15.

     Research output: Contribution to journal › Article › peer-review