1. Published

   Impact on the phased abolition of co-payments on the utilisation of selected prescription medicines in Wales

   Alam, M. F., Cohen, D., Dunstan, F., Hughes, D. & Routledge, P. A., Jan 2018, In: Health Economics. 27, 1, p. 236-243

   Research output: Contribution to journal › Article › peer-review

2. Published

   Impregnated central venous catheters for prevention of bloodstream infection in children (the CATCH trial): a randomised controlled trial

   Gilbert, R. E., Mok, Q., Dwan, K., Harron, K., Moitt, T., Millar, M., Ramnarayan, P., Tibby, S. M., Hughes, D. & Gamble, C. F., 23 Apr 2016, In: The Lancet. 387, 10029, p. 1732-1742

   Research output: Contribution to journal › Article › peer-review

3. Published

   Improving Medication Adherence Research Reporting: European Society for Patient Adherence, Compliance and Persistence Medication Adherence Reporting Guideline

   de Geest, S., Zullig, L., Dunbar-Jacobs, J., Hughes, D., Wilson, I. & Vrijens, B., Jun 2019, In: Journal of Cardiovascular Nursing. 34, 3, p. 199-200

   Research output: Contribution to journal › Editorial › peer-review

4. Published

   Improving Outcomes for People with Brain and Other CNS Tumours: Analysis of the Potential Economic Impact of the Guidance.

   Hughes, D., Linck, P., Priedane, E., Hughes, D. A. & Edwards, R. T., 1 Jan 2006, 2006 ed. Unknown.

   Research output: Book/Report › Commissioned report

5. Published

   Improving Outcomes for People with Sarcoma: Analysis of the Potential Economic Impact of the Guidance.

   Hughes, D., Linck, P., Hughes, D. A. & Edwards, R. T., 1 Jan 2006, 2006 ed. Unknown.

   Research output: Book/Report › Commissioned report

6. Published

   Improving Outcomes for People with Skin Tumours including Melanoma: Analysis of the Potential Economic Impact of the Guidance.

   Hughes, D., Linck, P., Hughes, D. A. & Edwards, R. T., 21 Feb 2006, Unknown.

   Research output: Book/Report › Commissioned report

7. Published

   Improving Outcomes in Children and Young People with Cancer: Analysis of the Potential Economic Impact of the Guidance.

   Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2005, 2005 ed. Unknown.

   Research output: Book/Report › Commissioned report

8. Published

   Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

   de Geest, S., Zullig, L. L., Dunbar-Jacob, J., Hughes, D., Wilson, I. & Vrijens, B., 1 Apr 2019, In: European Journal of Cardiovascular Nursing. 18, 4, p. 258-259 2 p.

   Research output: Contribution to journal › Editorial › peer-review

9. Published

   Incorporating measures of compliance and persistence in pharmacoeconomic evaluations

   Hughes, D., Hughes, D. A. & Cowell, W., 1 Nov 2005.

   Research output: Contribution to conference › Paper

10. Published

    Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care

    Swift, B., Jain, L., White, C., Chandrasekaran, V., Bhandari, A., Hughes, D. & Jadhav, P., Sept 2018, In: Clinical and Translational Science. 11, 5, p. 450-460 11 p.

    Research output: Contribution to journal › Article › peer-review

11. Published

    Integrating compliance and persistence in health economics models

    Hughes, D. & Hughes, D. A., 1 Jan 2008.

    Research output: Contribution to conference › Paper

12. Published

    Integration of Pharmacometrics and Pharmacoeconomics to Quantify the Value of Improved Forgiveness to Nonadherence: A Case Study of Novel Xanthine Oxidase Inhibitors for Gout

    Hill McManus, D., Marshall, S., Soto, E. & Hughes, D., Sept 2019, In: Clinical Pharmacology and Therapeutics. 106, 3, p. 652-660

    Research output: Contribution to journal › Article › peer-review

13. Published

    Internationalisation of cost-effectiveness model for on-demand use of proton pump inhibitors - Belgium.

    Hughes, D. & Hughes, D. A., 1 Jan 2004, 2004 ed. Unknown.

    Research output: Book/Report › Commissioned report

14. Published

    Internationalisation of cost-effectiveness model for on-demand use of proton pump inhibitors - Sweden.

    Hughes, D. & Hughes, D. A., 1 Jan 2005, 2005 ed. Unknown.

    Research output: Book/Report › Commissioned report

15. Published

    Interventions that enhance medication compliance and persistence: Theoretical grounding, and economic assessment

    Hughes, D., Hughes, D. A., Gwadry Sridhar, F., Elliott, R. & Cowell, W., 1 Oct 2007.

    Research output: Contribution to conference › Paper

16. Published

    Interventions to improve osteoporosis medication adherence and persistence: a systematic review and literature appraisal by the ISPOR Medication Adherence & Persistence Special Interest Group

    Hughes, D., Linck, P. G., Hiligsmann, M., Salas, M., Hughes, D. A., Manias, E., Gwadry-Sridhar, F. H., Linck, P. & Cowell, W., 1 Dec 2013, In: Osteoporosis International. 24, 12, p. 2907-2918

    Research output: Contribution to journal › Article › peer-review

17. Published

    Introduction to pharmaeconomics

    Hughes, D. & Hughes, D. A., 1 Jul 2004.

    Research output: Contribution to conference › Paper

18. Published

    Investigating factors influencing user choices to visit either general practioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment.

    Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

19. Published

    Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments

    Hughes, D. & Hughes, D. A., 1 May 2006.

    Research output: Contribution to conference › Paper

20. Published

    Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment

    Hughes, D., Myles, S., Hughes, D. A., Longo, M. & Lisles, C., 1 Jun 2006.

    Research output: Contribution to conference › Paper

21. Published

    Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments – piloting a discrete choice experiment

    Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Mar 2008

    Research output: Non-textual form › Web publication/site

22. Published

    Involving colleagues can be challenging

    Fargher, E. & Hughes, D., 2 Apr 2011, In: Pharmaceutical Journal. 286, p. 404

    Research output: Contribution to journal › Letter › peer-review

23. Published

    Is exercise effective in promoting mental well-being in older age? A systematic review.

    Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Aug 2010, In: Aging and Mental Health. 14, 6, p. 652-669

    Research output: Contribution to journal › Article › peer-review

24. Published

    Is there a role for Natural Desiccated Thyroid in the treatment of levothyroxine unresponsive hypothyroidism? Results from a Consecutive Case Series

    Heald, A., Premawardhana, L., Taylor, P., Okosieme, O., Bangi, T., Devine, H., Livingston, M., Javed, A., Moreno, G. Y. C., Watt, T., Stedman, M. & Hughes, D., 28 Dec 2021, In: International Journal of Clinical Practice. 75, 12, e14967.

    Research output: Contribution to journal › Article › peer-review

25. Published

    Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs

    Marson, A. G., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P. R., Baker, G., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., Dec 2021, In: Health Technology Assessment. 25, 75, 162 p.

    Research output: Contribution to journal › Article › peer-review

26. Published

    Less is more: Medicines that require less frequent administration improve adherence, but are they better?

    Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 3, p. 211-213

    Research output: Contribution to journal › Article › peer-review

27. Published

    Lessons learnt from a discontinued randomised controlled trial: Adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC)

    Williams, N., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Jul 2018, In: Trials. 19, 408.

    Research output: Contribution to journal › Article › peer-review

28. Published

    Letter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma

    Jenkinson, M., Weber, D., Haylock, B., Sherratt, F., Young, B., Weller, M., Bulbeck, H., Culeddu, G., Hughes, D., Brain, A., Das, K., Preusser, M., Francis, P. & Gamble, C., 17 Aug 2018, In: Journal of Neurology, Neurosurgery and Psychiatry.

    Research output: Contribution to journal › Letter › peer-review

29. Published

    Linked Pharmacometric-Pharmacoeconomic Modeling and Simulation in Clinical Drug Development

    Hill-McManus, D., Marshall, S., Liu, J., Willke, R. & Hughes, D., Jul 2021, In: Clinical Pharmacology and Therapeutics. 110, 1, p. 49-63

    Research output: Contribution to journal › Article › peer-review

30. Published

    Liothyronine for hypothyroidism: A candidate for disinvestment or in need of further research? A value of information analysis

    Hughes, D., Skiadas, K., Fitzsimmons, D., Anderson, P. & Heald, A., 3 Dec 2021, In: BMJ Open. 11, 12, e051702.

    Research output: Contribution to journal › Article › peer-review

31. Published

    Management of Patients Symptomatically Unresponsive to Levothyroxine: Natural Desiccated Thyroid Extract or the Combination of Levothyroxine and Liothyronine? A Research Priority

    Hughes, D., Livingston, M. & Heald, A., Sept 2020, In: Experimental and Clinical Endocrinology & Diabetes . 128, 9, p. 596-598

    Research output: Contribution to journal › Letter › peer-review

32. Published

    Managing Access to Advanced Therapy Medicinal Products: Challenges for NHS Wales

    Champion, A. R., Lewis, S., Davies, S. & Hughes, D., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2444-2449

    Research output: Contribution to journal › Article › peer-review

33. Published

    Mapping ALSFRS-R and ALSUI to EQ-5D in patients with motor neurone disease

    Moore, A., Young, C. A. & Hughes, D., Nov 2018, In: Value in Health. 21, 11, p. 1322-1329

    Research output: Contribution to journal › Article › peer-review

34. Published

    Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi.

    Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Hughes, D. A., Molyneux, M. E., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 26 Aug 2009, In: Malaria Journal. 8, p. 204

    Research output: Contribution to journal › Article › peer-review

35. Published

    Mechanism-Based Approach to the Economic Evaluation of Pharmaceuticals: Pharmacokinetic/Pharmacodynamic/Pharmacoeconomic Analysis of Rituximab for Follicular Lymphoma.

    Hughes, D., Pink, J., Lane, S. & Hughes, D. A., 19 Mar 2012, In: Pharmacoeconomics.

    Research output: Contribution to journal › Article › peer-review

36. Published

    Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial

    Johnson, S., Marshall, A., Hughes, D., Holmes, E., Henrich, F., Nurmikko, T., Sharma, M., Frank, B., Bassett, P., Marshall, A. & Goebel, A., 6 Nov 2021, In: Journal of Translational Medicine. 19, 1, 458.

    Research output: Contribution to journal › Article › peer-review

37. Published

    Medication adherence research comes of age

    Wright, D. F. B., Sinnappah, K. A. & Hughes, D., Jul 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 1914-1917

    Research output: Contribution to journal › Editorial › peer-review

38. Published

    Medication adherence – key considerations for clinical pharmacologists

    Hughes, D., Apr 2020, In: British Journal of Clinical Pharmacology. 86, 4, p. 628-629 2 p.

    Research output: Contribution to journal › Editorial › peer-review

39. Published

    Medicines Shortages in the United Kingdom

    Hughes, D., Oct 2019, In: Clinical Pharmacology and Therapeutics. 106, 4, p. 712

    Research output: Contribution to journal › Letter › peer-review

40. Published

    Medicines concordance and game theory.

    Hughes, D. & Hughes, D. A., 1 Oct 2008, In: British Journal of Clinical Pharmacology. 66, 4, p. 577

    Research output: Contribution to journal › Article › peer-review

41. Published

    Methodological Issues in the literature on costs of non-compliance in chronic diseases.

    Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008, In: Value in Health. 11, 6, p. A571-A572

    Research output: Contribution to journal › Article › peer-review

42. Published

    Methodological considerations on estimating medication adherence from self-report, electronic monitoring, and electronic healthcare databases using the TEOS framework

    Dima, A. L., Allemann, S. S., Dunbar-Jacob, J., Hughes, D., Vrijens, B. & Wilson, I., Jul 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 1918-1927

    Research output: Contribution to journal › Article › peer-review

43. Published

    Methodological issues in the literature on costs of non-compliance in chronic diseases

    Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008.

    Research output: Contribution to conference › Paper

44. Published

    Methods for Extrapolating Survival Analyses for the Economic Evaluation of Advanced Therapy Medicinal Products

    Hardy, W. & Hughes, D., 16 Sept 2022, In: Human Gene Therapy. 33, 17-18, p. 845-856

    Research output: Contribution to journal › Article › peer-review

45. Published

    Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations.

    Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Nov 2007, In: Value in Health. 10, 6, p. 498-509

    Research output: Contribution to journal › Article › peer-review

46. Published

    Methods for the collection of resource use data within clinical trials: A systematic review of studies funded by the UK Health Technology Assessment Program

    Ridyard, C. H. & Hughes, D., 1 Dec 2010, In: Value in Health. 13, 8, p. 867-872

    Research output: Contribution to journal › Article › peer-review

47. Published

    Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT

    Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Bostock, J., Hay, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. & Williamson, P. R., Apr 2021, In: Health Technology Assessment. 25, 24, 86 p.

    Research output: Contribution to journal › Article › peer-review

48. Published

    Modelling changes in first line antimalarial therapy

    Hughes, D. & Hughes, D. A., 1 Sept 2003.

    Research output: Contribution to conference › Paper

49. Published

    Modelling in health economics

    Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 141-154

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

50. Published

    Multiple imputation of multiple multi-item scales when a full imputation model is infeasible

    Hughes, D., Plumpton, C. O., Morris, T., Hughes, D. A. & White, I. R., 26 Jan 2016, In: BMC Research Notes. 9, 45, p. 1-15

    Research output: Contribution to journal › Article › peer-review

51. Published

    Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial

    Brogan, P. A., Arch, B., Hickey, H., Anton, J., Iglesias, E., Baildam, E., Mahmood, K., Cleary, G., Moraitis, E., Papadopoulou, C., Beresford, M. W., Riley, P., Demir, S., Ozen, S., Culeddu, G., Hughes, D., Dolezalova, P., Hampson, L., Whitehead, J., Jayne, D., Ruperto, N., Tudor-Smith, C. & Eleftheriou, D., Sept 2021, In: Arthritis and Rheumatology. 73, 9, p. 1673-1682

    Research output: Contribution to journal › Article › peer-review

52. Published

    NICE and new: appraising innovation.

    Hughes, D., Ferner, R. E., Hughes, D. A. & Aronson, J. K., 5 Jan 2010, In: British Medical Journal. 340, p. b5493

    Research output: Contribution to journal › Article › peer-review

53. Published

    NICE recommendations: why no disinvestment recommendations to offset investment decisions?

    Hughes, D., Tuersley, L. V., Hughes, D. A., Wood, E. M. & Tuersley, L., 19 May 2015, In: BMJ. 350

    Research output: Contribution to journal › Article › peer-review

54. Published

    New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes

    Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., May 2018, In: Pharmacoeconomics. 36, 5, p. 613-624 12 p.

    Research output: Contribution to journal › Article › peer-review

55. Published

    New advice on switching antiepileptic drugs might be a false economy

    Holmes, E. A., Plumpton, C. O., Hughes, D., Holmes, E., Plumpton, C., Duerden, M., Marson, T. & Hughes, D. A., 16 Dec 2013, In: British Medical Journal. 347

    Research output: Contribution to journal › Article › peer-review

56. Published

    New drugs for old: disinvestment and NICE.

    Hughes, D., Hughes, D. A. & Ferner, R. E., 25 Feb 2010, In: British Medical Journal. 340, p. c572

    Research output: Contribution to journal › Article › peer-review

57. Published

    Non-compliance with antibiotic therapy for acute community infections: A global survey.

    Hughes, D., Pechere, J. C., Hughes, D. A., Kardas, P. & Cornaglia, G., 1 Mar 2007, In: International Journal of Antimicrobial Agents. 29, 3, p. 245-253

    Research output: Contribution to journal › Article › peer-review

58. Published

    Novel oral iron therapy for iron deficiency anaemia: How to value safety in a new drug?

    Culeddu, G., Su, L., Chen, Y., Pereira, D. I. A., Powell, J. J. & Hughes, D., Mar 2022, In: British Journal of Clinical Pharmacology. 88, 3, p. 1347-1357 11 p.

    Research output: Contribution to journal › Article › peer-review

59. Published

    Nurse-led vs. conventional physician-led follow-up for patients with cancer: systematic review

    Lewis, R., Neal, R. D., Williams, N. H., France, B., Wilkinson, C. E., Hendry, M., Russell, D., Russell, I., Hughes, D., Stuart, N. S. & Weller, D., 1 Apr 2009, In: Journal of Advanced Nursing. 65, 4, p. 706-723

    Research output: Contribution to journal › Article › peer-review

60. Published

    Opportunity costs and local health service spending decisions: a qualitative study from Wales

    Schaffer, S. K., Sussex, J., Hughes, D. & Devlin, N., 25 Mar 2016, In: BMC Health Services Research. 16, 103

    Research output: Contribution to journal › Article › peer-review

61. Published

    Orphan drug treatments: economic considerations

    Hughes, D. & Hughes, D. A., 1 Nov 2007.

    Research output: Contribution to conference › Paper

62. Published

    Orphan drugs revisited: author's response.

    Hughes, D. & Hughes, D. A., 1 May 2006, In: Quarterly Journal of Medicine. 99, 5, p. 350-351

    Research output: Contribution to journal › Article › peer-review

63. Published

    Parenting programme for parents of children at risk of developing conduct disorder: cost effectiveness analysis.

    Bywater, T. J., Hutchings, J. M., Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 31 Mar 2007, In: British Medical Journal. 334, 7595, p. 682-685

    Research output: Contribution to journal › Article › peer-review

64. Published

    Patient compliance and persistence with prescribed medication: Measurement and health economic impact

    Hughes, D., Koncz, T., Hughes, D. A., Cleemput, I. & Annemans, L., 1 May 2004.

    Research output: Contribution to conference › Paper

65. Published

    Patient compliance and pharmacoeconomics

    Hughes, D. & Hughes, D. A., 1 Oct 2001.

    Research output: Contribution to conference › Paper

66. Published

    Patient compliance and pharmacoeconomics

    Hughes, D. & Hughes, D. A., 1 Nov 2002.

    Research output: Contribution to conference › Paper

67. Published

    Patient preferences for outcomes in clinical trials: implications for medicines optimization

    Holmes, E., Marson, A. G. & Hughes, D., 8 May 2017, In: Trials. 18 (Suppl 1), O18, p. 192 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

68. Published

    Patient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs

    Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Mar 2019, In: Clinical Pharmacology and Therapeutics. 105, 3, p. 672-683 12 p.

    Research output: Contribution to journal › Article › peer-review

69. E-pub ahead of print

    Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study

    Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L., 9 Apr 2024, (E-pub ahead of print) In: ACR Open Rheumatology.

    Research output: Contribution to journal › Article › peer-review

70. Published

    Patient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations

    Ridyard, C. & Hughes, D., 7 May 2017, p. P141. 1 p.

    Research output: Contribution to conference › Poster › peer-review

71. Published

    Patients' and healthcare professionals' views of cancer follow-up: systematic review

    Lewis, R., Neal, R. D., Hendry, M., France, B., Williams, N. H., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., Jul 2009, In: British Journal of General Practice. 59, 564, p. e248-e259

    Research output: Contribution to journal › Article › peer-review

72. Published

    Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

    Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A590

    Research output: Contribution to journal › Article › peer-review

73. Published

    Perceptions of European ME/CFS experts concerning knowledge and understanding of ME/CFS among primary care physicians in Europe: A report from the European ME/CFS Research Network (EUROMENE)

    Cullinan, J., Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 26 Feb 2021, In: Medicina. 57, 3, 208.

    Research output: Contribution to journal › Article › peer-review

74. Published

    Pharmacoeconomic evaluations in Ireland, Scotland and Wales: A Celtic perspective on pharmaceutical assessment

    Hughes, D., Hughes, D. A., Drummond, M., Tolley, K. & Ryan, M., 1 Oct 2007.

    Research output: Contribution to conference › Paper

75. Published

    Pharmacoeconomic models that incorporate non-compliance

    Hughes, D. & Hughes, D. A., 1 Jul 2004.

    Research output: Contribution to conference › Paper

76. Published

    Pharmacoeconomics appraisals by the all Wales medicines strategy group

    Hughes, D. & Hughes, D. A., 1 Jul 2004.

    Research output: Contribution to conference › Paper

77. Published

    Pharmacoeconomics in Wales: functions of the all Wales medicines strategy group

    Hughes, D. & Hughes, D. A., 1 Apr 2004.

    Research output: Contribution to conference › Paper

78. Published

    Pharmacoeconomics of pharmacogenetic testing: azathioprine

    Hughes, D., McAllister, R. & Hughes, D. A., 1 Apr 2004.

    Research output: Contribution to conference › Paper

79. Published

    Pharmacoeconomics: principles and relevance to the activities of drug and therapeutics committees.

    Hughes, D., Hughes, D. A. & Reynolds, D. J., 1 Oct 2009, In: Clinical Medicine. 9, 5, p. 490-492

    Research output: Contribution to journal › Article › peer-review

80. Published

    Pharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery

    Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Jul 2015, In: British Journal of Clinical Pharmacology. 80, 5, p. 1149-1159

    Research output: Contribution to journal › Article › peer-review

81. Published

    Pharmacogenetic tests: the need for a level playing field

    Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4

    Research output: Contribution to journal › Article › peer-review

82. Published

    Pharmacogenomics spotlight commentary: From the United Kingdom to global populations

    Magavern, E. F., Daly, A. K., Gilchrist, A. & Hughes, D., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4546-4548 3 p., 14917.

    Research output: Contribution to journal › Comment/debate › peer-review

83. Published

    Pharmacokinetic-Pharmacodynamic modelling of Lapdap (CPG-DDS) combination.

    Hughes, D., Hughes, D. A., Watkins, B. & Winstanley, P., 1 Jan 2001, 2001 ed. Unknown.

    Research output: Book/Report › Commissioned report

84. Published

    Pharmacokinetics, patient compliance and pharmaeconomics

    Hughes, D. & Hughes, D. A., 1 Jun 2005.

    Research output: Contribution to conference › Paper

85. Published

    Pharmacometric analysis of duration of drug action: implications for improved forgiveness to medication non-compliance

    Hughes, D., Hughes, D. A. & Walley, T., 1 Sept 2001.

    Research output: Contribution to conference › Paper

86. Published

    Physchiatrist prescribing preferences and attitudes toward promotion

    Hughes, D., Menkes, D., Davies, R. & Hughes, D. A., 1 Apr 2006.

    Research output: Contribution to conference › Paper

87. Published

    Plasma Methylmalonic Acid Concentration in Folic Acid–Supplemented Depressed Patients with Low or Marginal Vitamin B-12: A Randomized Trial

    Carter, B., Zenasni, Z., Moat, S. J., Hudson, P. R., Russell, I. T., McCaddon, A., Whitaker, R., Pink, J., Roberts, S., Wilkinson, C., Hughes, D., Betson, E., Carr, D., Jorgenson, A., Pirmohamed, M., Williams, N., Lewis, H., Lloyd, K., Sylvesture, Y. & Tranter, R., Dec 2021, In: Journal of Nutrition. 151, 12, p. 3738-3745 8 p.

    Research output: Contribution to journal › Article › peer-review

88. Published

    Policy on ultra-orphan drugs.

    Hughes, D. & Hughes, D. A., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

89. Published

    Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone.

    Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, G., Watkins, W. A. & Ward, S., 1 Mar 2006, In: British Journal of Clinical Pharmacology. 61, 3, p. 289-300

    Research output: Contribution to journal › Article › peer-review

90. Published

    Population pharmacokinetics of warfarin: Intermin analysis of the Liverpool pharmacogenetic prospective cohort study

    Hughes, D., Matthews, I., Aarons, L., Al-Zubiedi, S., Hatch, E., Lane, S., Williamson, P., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Nov 2007.

    Research output: Contribution to conference › Paper

91. Published

    PrEP use, sexual behaviour, and PrEP adherence among men who have sex with men living in Wales prior to and during the COVID-19 pandemic

    Gillespie, D., Couzens, Z., de Bruin, M., Hughes, D., Jones, A., Ma, R., Williams, A., Wood, F. & Blee, K., Aug 2022, In: AIDS and Behavior. 26, 8, p. 2746-2757 12 p.

    Research output: Contribution to journal › Article › peer-review

92. Published

    Pragmatic trials - design features and implications for clinical decision making

    Hughes, D., Urdahl, H., Hughes, D. A. & Freemantle, N., 1 Aug 2000.

    Research output: Contribution to conference › Paper

93. Published

    Predicting "real world" effectiveness by integrating adherence with pharmacodynamic modelling.

    Hughes, D., Hughes, D. A. & Walley, T., 1 Jul 2003, In: Clinical Pharmacology and Therapeutics. 74, 1, p. 1-8

    Research output: Contribution to journal › Article › peer-review

94. Published

    Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research

    Holmes, E. A., Morrison, V. L. & Hughes, D., 8 Dec 2014, In: Value in Health. 17, 8, p. 863-876

    Research output: Contribution to journal › Article › peer-review

95. Published

    Predictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey

    Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Mar 2015, In: Value in Health. 18, 2, p. 206-216

    Research output: Contribution to journal › Article › peer-review

96. Published

    Prescription fee exemption research study

    Hughes, D., Myles, S., Hughes, D. A., Routledge, P. & Wales, D. F., 1 Jun 2006.

    Research output: Contribution to conference › Paper

97. Published

    Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study

    Hughes, D. & Poletti-Hughes, J., 21 Oct 2016, In: PLoS ONE. 11, 10, e0164681.

    Research output: Contribution to journal › Article › peer-review

98. Published

    Psychometric properties of an adapted stigma scale and experiences of stigma associated with HIV pre-exposure prophylaxis use among men who have sex with men: a mixed methods study

    Gillespie, D. & Hughes, D., Jul 2023, In: AIDS and Behavior. 27, 7, p. 2397-2410 14 p.

    Research output: Contribution to journal › Article › peer-review

99. Published

    Public funding of drugs for orphan diseases

    Hughes, D. & Hughes, D. A., 11 Nov 2005, In: Value in Health. 8, 6, p. A192

    Research output: Contribution to journal › Article › peer-review

100. Published

     Public funding of drugs for orphan diseases

     Hughes, D. & Hughes, D. A., 1 Nov 2005.

     Research output: Contribution to conference › Paper

101. Published

     Public funding of drugs for orphan diseases

     Hughes, D. & Hughes, D. A., 1 Nov 2005.

     Research output: Contribution to conference › Paper

102. Published

     Public funding of drugs for orphan diseases

     Hughes, D. & Hughes, D. A., 1 Jan 2006.

     Research output: Contribution to conference › Paper

103. Published

     Public funding of drugs for orphan diseases

     Hughes, D. & Hughes, D. A., 1 Jul 2005.

     Research output: Contribution to conference › Paper

104. Published

     Public health interventions to promote mental well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

     Hughes, D., Windle, G., Hughes, D. A., Linck, P., Morgan, R., Burholt, V., Edwards, R. T., Reeves, C., Yeo, S. T., Woods, R. T. & Russell, I. T., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

105. Published

     Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

     Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T., Morgan, R., Woods, R. T., Burholt, V., Edwards, R. T., Reeves, C. & Yeo, S. T., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

106. Published

     Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness: Evidence Tables.

     Hughes, D., Linck, P. G., Windle, G., Linck, P., Morgan, R., Hughes, D. A., Burholt, V., Reeves, C., Yeo, S. T., Woods, R. T., Edwards, R. T. & Russell, I. T., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

107. Published

     Public meetings of the NICE appraisals committee

     Hughes, D. & Hughes, D. A., 1 Dec 2007.

     Research output: Contribution to conference › Paper

108. Published

     Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

     Ridyard, C., Blair, J. & Hughes, D., Nov 2017, In: Value in Health. 20, 9, p. A481 - A482

     Research output: Contribution to journal › Article › peer-review

109. Published

     Quantitative evidence synthesis methods for the assessment of the effectiveness of treatment sequences for clinical and economic decision-making: a review and taxonomy of simplifying assumptions

     Lewis, R., Hughes, D., Sutton, AJ. & Wilkinson, C., Jan 2021, In: PharmacoEconomics. 39, 1, p. 25-61 37 p.

     Research output: Contribution to journal › Article › peer-review

110. Published

     Quantitative risk-benefit analysis

     Hughes, D. & Hughes, D. A., 1 May 2007.

     Research output: Contribution to conference › Paper

111. Published

     RES00019. Wales COVID-19 Evidence Centre. A rapid evidence summary indicating the evidence of the inverse care law in social care in Wales and has this been exacerbated by the COVID-19 pandemic?

     Spencer, L., Hendry, A., Makanjuola, A., Hughes, D., Wilkinson, C., Pisavadia, K., Davies, J., Fitzsimmons, D. & Edwards, R. T., Feb 2022, Welsh Government. 33 p.

     Research output: Book/Report › Other report

112. Published

     RES00038. Wales COVID-19 Evidence Centre. A rapid evidence summary of the cost impact of Long COVID on employment and caring responsibilities

     Spencer, L., Hendry, A., Davies, J., Pisavadia, K., Hughes, D. & Edwards, R. T., May 2022, Welsh Government. 18 p.

     Research output: Book/Report › Other report

113. Published

     Rare Disease Terminology and Definitions—A Systematic Global Review: Report of the ISPOR Rare Disease Special Interest Group

     Hughes, D., Richter, T., Nestler-Parr, S., Babela, R., Khan, Z. M., Tesoro, T., Molsen, E. & Hughes, D. A., 18 Aug 2015, In: Value in Health. 18, 6, p. 906-914

     Research output: Contribution to journal › Article › peer-review

114. Published

     Rare disease prevention and treatment: The need for a level playing field

     Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247

     Research output: Contribution to journal › Article › peer-review

115. Published

     Rationing of drugs for rare diseases

     Hughes, D. & Hughes, D. A., 1 Apr 2006.

     Research output: Contribution to conference › Paper

116. Published

     Rationing of drugs for rare diseases.

     Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 4, p. 315-316

     Research output: Contribution to journal › Article › peer-review

117. Published

     Reimbursement Decisions of the All Wales Medicines Strategy Group

     Hughes, D., Linley, W. G. & Hughes, D. A., 1 Sept 2012, In: PharmoEconomics. 30, 9, p. 779-794

     Research output: Contribution to journal › Article › peer-review

118. Published

     Renal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment

     Hagemi, A., Plumpton, C. & Hughes, D., 2 Oct 2017, In: BMC Nephrology. 18, 305.

     Research output: Contribution to journal › Article › peer-review

119. Published

     Resource-Use Measurement Based on Patient Recall: Issues and Challenges for Economic Evaluation

     Thorn, J. C., Coast, J., Cohen, D., Hollingworth, W., Knapp, M., Noble, S. M., Ridyard, C. H., Wordsworth, S. & Hughes, D., 1 Jun 2013, In: Applied Health Economics and Health Policy. 11, 3, p. 155-161

     Research output: Contribution to journal › Article › peer-review

120. Published

     Review of resource-use measures in UK economic evaluations

     Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (eds.). University of Kent, Canterbury, p. 22-31 10 p.

     Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

121. Published

     Review of the Use of Resource Use Instruments Based on Patient Recall in Relation to Other Methods of Cost Estimation

     Ridyard, C. & Hughes, D., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

122. Published

     Review of the use of resource use instruments based on patient recall in relation to other methods of resource use estimation

     Ridyard, C. & Hughes, D., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

123. Published

     Screening log data can be used to inform protocol modifications, increasing patient recrutiment to a challanging clinical trial

     Blair, J., Awoyale, L., Thornborough, K., Peak, M., Didi, M., Bedson, E., Hughes, D., Ridyard, C., Tat, T. & Gregory, J., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

124. Published

     Seizure First Aid Training For people with Epilepsy (SAFE) frequently attending emergency departments and their significant others: results of a UK multi-centre randomised controlled pilot trial

     Noble, A. J., Snape, D., Nevitt, S., Holmes, E., Morgan, M., Smith, C. T., Hughes, D., Buchanan, M., McVicar, J., MacCallum, E., Goodacre, S., Rinsdale, L. & Marson, A. G., 16 Apr 2020, In: BMJ Open. 10, 4, e035516.

     Research output: Contribution to journal › Article › peer-review

125. Published

     Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project

     Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 17-27 11 p.

     Research output: Contribution to journal › Article › peer-review

126. Published

     Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT

     Mallucci, C. L., Jenkinson, M., Conroy, E. J., Hartley, J. C., Brown, M., Moitt, T., Dalton, J., Kearns, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 2 Apr 2020, In: Health Technology Assessment. 24, 17, 114 p.

     Research output: Contribution to journal › Article › peer-review

127. Published

     Societal perspective on access to publicly subsidised medicines: A cross sectional survey of 3080 adults in Australia

     Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 1 Mar 2017, In: PLoS ONE.

     Research output: Contribution to journal › Article › peer-review

128. Published

     Societal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods

     Bourke, S. M., Plumpton, C. & Hughes, D., 9 May 2018, In: Value in Health. 21, 5, p. 538-546

     Research output: Contribution to journal › Article › peer-review

129. Published

     Societal views on NICE, cancer drugs fund and value-based pricing criteria for prioritising medicines: a cross-sectional survey of 4118 adults in Great Britain

     Hughes, D., Linley, W. G. & Hughes, D. A., 1 Aug 2013, In: Health Economics. 22, 8, p. 948-964

     Research output: Contribution to journal › Article › peer-review

130. Published

     Statistical Methods for Adjusting Estimates of Treatment Effectiveness for Patient Non-adherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Systematic Review of Methodological Papers

     Alshreef, A., Latimer, N., Tappenden, P., Wong, R., Hughes, D., Fotheringham, J. & Dixon, S., Nov 2019, In: Medical Decision Making. 39, 8, p. 910-925 16 p.

     Research output: Contribution to journal › Article › peer-review

131. Published

     Statistical comments are unfounded.

     Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Mar 2008, In: Value in Health. 11, 2, p. 346

     Research output: Contribution to journal › Article › peer-review

132. Published

     Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)

     Balabanova, S., Taylor, C., Sills, G., Burnside, G., Plumpton, C., Smith, P., Appleton, R., Leach, J. P., Johnson, M., Baker, G. A., Pirmohamed, M., Hughes, D., Williamson, P., Tudor-Smith, C. & Marson, A. G., 26 Aug 2020, In: BMJ Open. 10, 8, e040635.

     Research output: Contribution to journal › Article › peer-review

133. Published

     Study protocol for a randomised controlled trial of insulin delivery by continuous subcutaneous infusion compared to multiple daily injections

     Blair, J., Gregory, J., Hughes, D., Ridyard, C., Gamble, C., McKay, A., Didi, M., Thornborough, K., Bedson, E., Awoyale, L., Cwiklinski, E. & Peak, M., 16 Apr 2015, In: Trials. 16, 163.

     Research output: Contribution to journal › Article › peer-review

134. Published

     Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica

     Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Oct 2017, In: Health Technology Assessment. 21, 60, p. 1-180 180 p.

     Research output: Contribution to journal › Article › peer-review

135. Published

     Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial

     Marsden, J., Kelleher, M., Gilvarry, E., Mitcheson, L., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hardy, W., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Vanderwaal, R., Wareham, A., Hughes, D. & Hoare, Z., Dec 2023, In: eClinicalMedicine. 66, 23 p., 102331.

     Research output: Contribution to journal › Article › peer-review

136. Published

     Supply-side cost-effectiveness thresholds: questions for evidence-based policy

     Sampson, C., Zamora, B., Watson, S., Cairns, J., Chalkidou, K., Cubi-Molla, P., Devlin, N., García-Lorenzo, B., Hughes, D., Leech, A. & Towse, A., Sept 2022, In: Applied Health Economics and Health Policy. 20, 5, p. 651-667

     Research output: Contribution to journal › Article › peer-review

137. Published

     Supporting People With Type 2 Diabetes in the Effective Use of Their Medicine Through Mobile Health Technology Integrated With Clinical Care to Reduce Cardiovascular Risk: Protocol for an Effectiveness and Cost-effectiveness Randomized Controlled Trial

     Farmer, A. J., Jones, L., Newhouse, N., Kenning, C., Williams, N., Chi, Y., Bartlett, K., Plumpton, C., McSharry, J., Cholerton, R., Holmes, E., Robinson, S., Allen, J., Gudgin, B., Velardo, C., Rutter, H., Horne, R., Tarassenko, L., Williams, V., Locock, L., Rea, R., Yu, L-M., Hughes, D., Bower, P. & French, D. P., 21 Feb 2022, In: JMIR Research Protocols. 11, 2, e32918.

     Research output: Contribution to journal › Article › peer-review

138. Published

     Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol

     Farmer, A. J., Allen, J., Bartlett, K., Bower, P., Chi, Y., French, D. P., Gudgin, B., Holmes, E., Horne, R., Hughes, D., Kenning, C., Locock, L., McSharry, J., Miles, L., Newhouse, N., Rea, R., Riga, J., Tarassenko, L., Velardo, C., Williams, N., Williams, V. & Yu, L-M., 29 Dec 2019, In: BMJ Open. 9, 12, e033504.

     Research output: Contribution to journal › Article › peer-review

139. E-pub ahead of print

     Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial

     SuMMiT-D Collaborative Group , 25 Jan 2024, (E-pub ahead of print) In: Pilot and Feasibility Studies. 10, 1, 15.

     Research output: Contribution to journal › Article › peer-review

140. Published

     Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation

     Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. G. & Williamson, P., 1 May 2021, In: The Lancet Rheumatology. 3, 5, p. e347-e356

     Research output: Contribution to journal › Article › peer-review

141. Published

     Systematic Review: Outcomes and adverse events from randomised trials in Crohn's disease

     Catt, H., Hughes, D., Kirkham, J. K. & Bodger, K., Apr 2019, In: Alimentary Pharmacology and Therapeutics. 49, 8, p. 978-996 19 p.

     Research output: Contribution to journal › Article › peer-review

142. Published

     Systematic review of follow-up of cancer in primary care verses secondary care: findings for breast and lung cancer

     Hughes, D., Lewis, R., Neal, R. D., France, B., Williams, N. H., Wilkinson, C., Russell, I. T., Russell, D., Hughes, D. A., Stuart, N. S. & Weller, D., 1 Mar 2007.

     Research output: Contribution to conference › Paper

143. Published

     TEOS: A framework for constructing operational definitions of medication adherence based on Timelines – Events – Objectives – Sources

     Dima, A. L., Allemann, S. S., Dunbar-Jacobs, J., Hughes, D., Vrijens, B. & Wilson, I., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2521-2533

     Research output: Contribution to journal › Article › peer-review

144. Published

     Taxonomy for methods of resource use measurement

     DIRUM Team, 23 Jan 2015, In: Health Economics. 24, 3, p. 372-378

     Research output: Contribution to journal › Letter › peer-review

145. Published

     The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol

     Hughes, D., Jenkinson, M. D., Gamble, C., Hartley, J. C., Hickey, H., Hughes, D. A., Blundell, M., Griffiths, M. J., Solomon, T. & Malluci, C. L., 3 Jan 2014, In: Trials. 15, 14

     Research output: Contribution to journal › Article › peer-review

146. Published

     The Development of a Consistent Europe-Wide Approach to Investigating the Economic Impact of Myalgic Encephalomyelitis (ME/CFS): A Report from the European Network on ME/CFS (EUROMENE)

     Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 7 Apr 2020, In: Healthcare. 8, 2, 88.

     Research output: Contribution to journal › Article › peer-review

147. Published

     The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

     Hughes, D., Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Jan 2012, In: British Journal of Clinical Pharmacology. 73, 1, p. 66-76

     Research output: Contribution to journal › Article › peer-review

148. Published

     The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial

     Jenkinson, M. D., Javadpour, M., Haylock, B. J., Young, B., Gillard, H., Vinten, J., Bulbeck, H., Das, K., Farrell, M., Looby, S., Hickey, H., Preusser, M., Mallucci, C. L., Hughes, D., Gamble, C. & Weber, D. C., 14 Nov 2015, In: Trials. 16

     Research output: Contribution to journal › Article › peer-review

149. Published

     The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

     Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1363-1374

     Research output: Contribution to journal › Article › peer-review

150. Published

     The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

     Marson, A., Burnside, G., Appleton, R., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1375-1386

     Research output: Contribution to journal › Article › peer-review

151. Published

     The all wales medicines strategy group: assessments and appraisals

     Hughes, D. & Hughes, D. A., 1 Nov 2008.

     Research output: Contribution to conference › Paper

152. Published

     The assessment, determinants & economics of medication compliance & persistence

     Hughes, D., Hughes, D. A., Gwadry Sridhar, F. & Elliott, R., 1 Oct 2007.

     Research output: Contribution to conference › Paper

153. Published

     The cost-effectiveness of biological therapies for Crohn's disease: Markov cohort analyses incorporating UK patient-level cost data

     Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Mar 2008.

     Research output: Contribution to conference › Paper

154. Published

     The cost-effectiveness of biological therapies for Crohn's disease: markov cohot analyses incorporating UK patient-level cost data

     Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 May 2008.

     Research output: Contribution to conference › Paper

155. Published

     The costs and cost-effectiveness of different service models of palliatice care, focusing on end of life care: A rapid review

     Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Gillen, E., Noyes, J., Fitzsimmons, D., Lewis, R., Cooper, A., Hughes, D., Edwards, R. T. & Edwards, A., 7 Mar 2024, MedRxiv, 118 p.

     Research output: Working paper › Preprint

156. Published

     The development of a QALY measure for epilepsy: NEWQOL-6D

     Hughes, D., Mulhern, B., Rowen, D., Jacoby, A., Marson, T., Snape, D., Hughes, D. A., Latimer, N., Baker, G. A. & Brazier, J. E., 1 May 2012, In: Epilepsy and Behavior. 24, 1, p. 36-43

     Research output: Contribution to journal › Article › peer-review

157. Published

     The difference between effectiveness and efficacy of antimalarial drugs in Kenya.

     Hughes, D., Amin, A. A., Hughes, D. A., Marsh, V., Abuya, T. O., Kokwaro, G. O., Winstanley, P. A., Ochala, S. A. & Snow, R. W., 1 Sept 2004, In: Tropical Medicine and International Health. 9, 9, p. 967-974

     Research output: Contribution to journal › Article › peer-review

158. Published

     The economics of evergreening.

     Hughes, D. & Hughes, D. A., 1 Jan 2009.

     Research output: Contribution to conference › Paper

159. Published

     The effect of compliance upon clinical effectiveness of chlorproguanil-dapsone (CD) and artemether-lumefantrine (AL) when compared to sulfadoxine-pyrimethamine (SP) for the treatment of uncomplicated falcipaum malaria in Malawi - a randomised controlled trial

     Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Zijlstra, E., Hughes D.A., N. V., Molyneux M.E.*, N. V., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 1 Nov 2007.

     Research output: Contribution to conference › Paper

160. Published

     The experiences and perspectives of people with gout on urate self-monitoring

     Michael, T. J. F., Chan, J. S., Hughes, S., Wright, D. F. B., Coleshill, M. J., Hughes, D., Day, R. O., Aslani, P. & Stocker, S. L., Jun 2024, In: Health Expectations. 27, 3, 9 p., e14071.

     Research output: Contribution to journal › Article › peer-review

161. Published

     The future challenges

     Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 167-174

     Research output: Chapter in Book/Report/Conference proceeding › Chapter

162. Published

     The impact of non-compliance on the cost-effectiveness of pharmaceuticals: A review of the literature.

     Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Oct 2001, In: Health Economics. 10, 7, p. 601-615

     Research output: Contribution to journal › Article › peer-review

163. Published

     The impact of parent treatment preference and other factors on recruitment: lessons learned from a paediatric epilepsy randomised controlled trial

     Carter, B., Bray, L., Al-Najjar, N., Tort Piella, A., Smith, C. T., Spowart, C., Collingwood, A., Crudgington, H., Currier, J., Hughes, D., Wood, E., Martin, R., Morris, C., Roberts, D., Rouncefield-Swales, A., Sutherland, H., Watson, V., Cook, G., Wiggs, L., Gringas, P. & Pal, D., 6 Feb 2023, In: Trials. 24, 1, 83.

     Research output: Contribution to journal › Article › peer-review

164. Published

     The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies

     Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Jan 2000, In: Value in Health. 3, 5, p. 373

     Research output: Contribution to journal › Article › peer-review

165. Published

     The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies

     Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Nov 2000.

     Research output: Contribution to conference › Paper

166. Published

     The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies.

     Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

     Research output: Book/Report › Commissioned report

167. Published

     The new and non-transparent Cancer Drugs Fund

     Wood, E. & Hughes, D., Jan 2020, In: PharmacoEconomics. 38, 1, p. 1-4

     Research output: Contribution to journal › Article › peer-review

168. Published

     The pharmacokinetic profile of Warfarn: a systematic review

     Hughes, D., Al-Zubiedi S.*, N. V., Hughes D.A., N. V. & Pirmohamed, M., 1 Dec 2007.

     Research output: Contribution to conference › Paper

169. Published

     The population pharmacokinetics of lapdap

     Hughes, D., Ward, S., Simpson, J., Aarons, L., Szwandt, S. & Hughes, D. A., 1 Nov 2002.

     Research output: Contribution to conference › Paper

170. Published

     The problem of orphan drugs

     Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Nov 2010, In: British Medical Journal. 341, p. 335-341

     Research output: Contribution to journal › Article › peer-review

171. Published

     The role of prevention in reducing the economic impact of ME/CFS in Europe: A report from the socioeconomics working group of the European Network on ME/CFS (EUROMENE).

     Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 16 Apr 2021, In: Medicina. 57, 4, 388.

     Research output: Contribution to journal › Article › peer-review

172. Published

     Trends and influences on use of antidiabetic drugs in England, 1992-2003.

     Walley, T., Hughes, D. & Kendall, H., 1 Nov 2005, In: Pharmacoepidemiology and Drug Safety. 14, 11, p. 769-773

     Research output: Contribution to journal › Article › peer-review

173. Published

     Ultra-long acting pharmaceuticals: Do they result in better outcomes, and at an acceptable cost?

     Hughes, D. & Hughes, D. A., 1 Nov 2006.

     Research output: Contribution to conference › Paper

174. Published

     Understanding medication compliance and persistence from an economics perspective

     Hughes, D., Elliot, R. A., Shinogle, J. A., Peele, P., Bhosle, M. & Hughes, D. A., 1 Jan 2008, In: Value in Health. 11, 4, p. 600-610

     Research output: Contribution to journal › Article › peer-review

175. Published

     Use Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients

     Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A580

     Research output: Contribution to journal › Article › peer-review

176. Published

     Use of PK-PD modelling to predict the impact of non-compliance

     Hughes, D. & Hughes, D. A., 1 Nov 2003.

     Research output: Contribution to conference › Paper

177. Published

     Using Routinely Recorded Data in a UK RCT: A Comparison to Standard Prospective Data Collection Methods

     Powell, G., Bonnett, L., Tudor-Smith, C., Hughes, D., Williamson, P. R. & Marson, A. G., 5 Jul 2021, In: Trials. 22, 1, 429.

     Research output: Contribution to journal › Article › peer-review

178. Published

     Using Routinely Recorded Data in the UK to Assess Outcomes in a Randomised Controlled Trial: The Trials of Access

     Powell, G., Bonnett, L., Smith, C. T., Hughes, D., Williamson, P. & Marson, A., 23 Aug 2017, In: Trials. 18, 11 p., 389.

     Research output: Contribution to journal › Article › peer-review

179. Published

     Utilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project

     Totton, N., Julious, S., Hughes, D., Cook, J., Biggs, K., Coates, L., Cook, A., Hewitt, C. & Day, S., 19 Jan 2021, In: Trials. 22, 68.

     Research output: Contribution to journal › Article › peer-review

180. Published

     Valuations of epilepsy-specific health states: a comparison of patients with epilepsy and the general population

     Hughes, D., Mulhern, B., Rowen, D., Snape, D., Jacoby, A., Marson, T., Hughes, D. A., Baker, G. & Brazier, J., 1 Jul 2014, In: Epilepsy and Behavior. 36, p. 12-17

     Research output: Contribution to journal › Article › peer-review

181. Published

     Value assessment and quantitative benefit-risk modelling of biosimilar infliximab for Crohn’s disease

     Catt, H., Bodger, K., Hughes, D. & Kirkham, J. J., Dec 2019, In: PharmacoEconomics. 37, 12, p. 1509-1523 15 p.

     Research output: Contribution to journal › Article › peer-review

182. Published

     Value of improving patient safety: Health-economic considerations for Rapid Response Systems – a Rapid Review of the Literature and Expert Round Table

     Subbe, C., Hughes, D., Lewis, S., Holmes, E., Kalkman, C. J., So, R. K., Tranka, S. & Welch, J., 17 Apr 2023, In: BMJ Open. 13, 4, e065819.

     Research output: Contribution to journal › Article › peer-review

183. Published

     Value-Based Pricing: Incentive for Innovation or Zero Net Benefit?

     Hughes, D. & Hughes, D. A., 1 Sept 2011, In: Pharmacoeconomics. 29, 9, p. 731-735

     Research output: Contribution to journal › Article › peer-review

184. Published

     Warfarin pharmacogenetics: Economic considerations.

     Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Jan 2007, In: Pharmacoeconomics. 25, 11, p. 899-902

     Research output: Contribution to journal › Article › peer-review

185. E-pub ahead of print

     We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment

     Hughes, D., 27 Sept 2023, (E-pub ahead of print) In: Health Economics, Policy and Law.

     Research output: Contribution to journal › Article › peer-review

186. Published

     Welsh Health Economics Network (WHEN): Scoping Report.

     Hughes, D., Farr, A., O Ceilleachair, A., Cohen, D., Hughes, D. A. & Phillips, C., 1 Jan 2005, 2005 ed. Unknown.

     Research output: Book/Report › Commissioned report

187. Published

     What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?

     Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.

     Research output: Contribution to conference › Paper

188. Published

     What influences persistence with medicines? A multinational discrete choice experiment of 2549 patients

     Holmes, E. A., Morrison, V. L. & Hughes, D., Aug 2016, In: British Journal of Clinical Pharmacology. 82, 2, p. 522-531

     Research output: Contribution to journal › Article › peer-review

189. Published

     What innovations can address inequalities experienced by women and girls due to the COVID-19 pandemic across the different areas of life/domains: work, health, living standards, personal security, participation and education? Report number – RR00027 (January 2022). Gender Inequalities: COVID-19 initiatives

     Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Pisavadia, K., Davies, J., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 15 Jan 2022, Health and Care Research Wales.

     Research output: Book/Report › Commissioned report › peer-review

190. Published

     What interventions or best practice are there to support people with Long COVID, or similar post-viral conditions or conditions characterised by fatigue, to return to normal activities: a rapid review

     Spencer, L., Hendry, A., Makanjuola, A., Anthony, B., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 28 Jan 2023, 34 p. (MedRxiv).

     Research output: Working paper › Preprint

191. Published

     What is the effectiveness and cost-effectiveness of interventions in reducing the harms for children and young people who have been exposed to domestic violence or abuse: a rapid review.

     Spencer, L., Hendry, A., Makanjuola, A., Pisavadia, K., Davies, J., Albustami, M., Anthony, B., Wilkinson, C., Fitzsimmons, D., Hughes, D., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 10 May 2023, 79 p.

     Research output: Book/Report › Commissioned report

192. Published

     What is the long-term impact of COVID-19 on the Health-Related Quality of Life of individuals with mild symptoms (or non-hospitalised): A rapid review

     Spencer, L., Hendry, A., Makanjuola, A., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 9 Sept 2022, Health and Care Research Wales, 47 p.

     Research output: Working paper › Preprint

193. Published

     What really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK

     Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Jun 2019, In: Epilepsy and Behavior. 95, p. 181-191

     Research output: Contribution to journal › Article › peer-review

194. Published

     What should patients do if they miss a dose? A systematic review of patient information leaflets and summaries of product characteristics

     Albassam, A. & Hughes, D., Feb 2021, In: European Journal of Clinical Pharmacology. 77, 2, p. 251-260 10 p.

     Research output: Contribution to journal › Article › peer-review

195. Published

     When drugs don't work - Economic assessment of enhancing compliance with interventions supported by electronic monitoring devices.

     Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Pharmacoeconomics. 25, 8, p. 621-635

     Research output: Contribution to journal › Article › peer-review

196. Published

     ‘Seizure First Aid Training’ for people with epilepsy who attend emergency departments, and their family and friends: study protocol for intervention development and a pilot randomised controlled trial

     Noble, A. J., Marson, A. G., Tudur-Smith, C., Morgan, M., Hughes, D., Goodacre, S. & Ridsdale, L., 24 Jul 2015, In: BMJ Open. 5, 7

     Research output: Contribution to journal › Article › peer-review