C2-Symmetric Amino Acid Amide-Derived Organocatalysts

Al-Taie, Z., Coles, S. J., Horton, P., Kraehenbuehl, R., Murphy, P. & Tizzard, G., 24 Aug 2024, In: Reactions. 5, 3, p. 567-586

Research output: Contribution to journal › Article › peer-review

Cyclic guanidine containing amino acids that promote glucocerebrosidase

Al-Taie, Z. S., Bartholomew, B., Coles, S. J., Evans, D. M., Hollinshead, J., Jones, L. F., Kraehenbuehl, R., Murphy, P. J., Nash, R. J., Penkova, Y. B. & Tizzard, G. J., 24 Sept 2022, In: Tetrahedron. 123, 132959.

Research output: Contribution to journal › Article › peer-review

Synthesis of (+)-(R)-Tiruchanduramine

Al-Taie, Z. S., Bartholomew, B., Cartmell, C., Froom, R., Kerr, R. G., Kraehenbuehl, R., Murphy, P., Nash, R. J., Penkova, Y. B. & van Teijlingen, A., 16 Feb 2022, In: Molecules. 27, 4

Research output: Contribution to journal › Article › peer-review

Propiedades electroquímicas y espectroscópicas de los ditieniletilenos y sus polímeros

Anjos, T., Altaie, Z., Roberts-Bleming, S. J., Kalaji, M. & Murphy, P., 2022, In: Revista de Ingenieria y Tecnologia Educativa. 5, 1, p. 41-55

Research output: Contribution to journal › Article › peer-review

Synthetic Route to 1,1′,2,2′-Tetraiodoferrocene That Avoids Isomerization and the Electrochemistry of Some Tetrahaloferrocenes

Evans, D. M., Hughes, D. D., Murphy, P. J., Horton, P. N., Coles, S. J., de Biani, F. F., Corsini, M. & Butler, I. R., 9 Aug 2021, In: Organometalics. 40, 15, p. 2496-2503 8 p.

Research output: Contribution to journal › Article › peer-review

N-carbamate protected amino acid derived guanidine organocatalysts

Al-Taie, Z. S., Anderson, J. M., Bischoff, L., Christensen, J., Coles, S. J., Froom, R., Gibbard, M. E., Jones, L. F., de Kleijne, F. F. J., Murphy, P. & Thompson, E., 4 Jun 2021, In: Tetrahedron. 89, 132093.

Research output: Contribution to journal › Article › peer-review

1,1′,2,2′-Tetralithioferrocene and 1,1′,2,2′,3,3′-Hexalithioferrocene: Useful Additions to Ferrocene Precursor Compounds

Butler, I., Evans, D., Horton, P., Coles, S. & Murphy, P., 8 Mar 2021, In: Organometallics. 40, 5, p. 600-605 6 p.

Research output: Contribution to journal › Article › peer-review

Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal

Whiteland, H., Crusco, A., Bloemberg, L. W., Tibble-Howlings, J., Forde-Thomas, J., Coghlan, A., Murphy, P. J. & Hoffmann, K. F., 19 Oct 2020, In: PLoS Neglected Tropical Diseases. 14, 10, p. e0008630

Research output: Contribution to journal › Article › peer-review

Synthesis of Zephycandidine A from Haemanthamine

Murphy, P., Tibble-Howlings, J., Kowalczyk, R. M. & Stevens, K., 16 Apr 2020, In: Tetrahedron Letters. 61, 16, 151785.

Research output: Contribution to journal › Article › peer-review

Polymethoxy-1-Alkenes Screening of Chlorella and Spirulina Food Supplements Coupled with In Vivo Toxicity Studies

Henao, E., Murphy, P., Falfushynska, H., Horyn, O., Evans, D. & Rzymski, P., Feb 2020, In: Toxins. 12, 2, 111.

Research output: Contribution to journal › Article › peer-review

A study of polymethoxy-1-alkenes in Raphidiopsis (Cylindrospermopsis) raciborskii and Aphanizomenon gracile isolated in Poland

Rzymskic, P., Evans, D., Murphy, P. & Kokocinski, M., 5 Dec 2019, In: Toxicon. 171, p. 51-53

Research output: Contribution to journal › Article › peer-review

Elucidating cylindrospermopsin toxicity via synthetic analogues: An in vitro approach

Murphy, P., Evans, D., Hughes , J., Jones, L., Falfushynska, H., Horyn, O., Sokolova, I., Christensen, J., Coles, S. & Rzymskic, P., Nov 2019, In: Chemosphere. 234, p. 139-147 9 p.

Research output: Contribution to journal › Article › peer-review

Slight changes in the chemical structure of haemanthamine greatly influence the effect of the derivatives on rumen fermentation in vitro

Ramos-Morales, E., Braganca, R., Murphy, P., Tibble-Howlings, J. & Newbold, C. J., 21 Feb 2019, In: Scientific Reports. 8 p.

Research output: Contribution to journal › Article › peer-review

Synthetic analogues of cyanobacterial alkaloid cylindrospermopsin and their toxicological activity

Cartmell, C., Evans, D., Elwood, J. M., Fituri, H., Murphy, P., Caspari, T., Poniedziałekc, B. & Rzymskic, P., Oct 2017, In: Toxicology in Vitro. 44, p. 172-181

Research output: Contribution to journal › Article › peer-review

A synthesis of tiruchanduramine and a reinvestigation of its glycosidase inhibitory activity

Buck, M., Evans, D., Evans, V. A., Herkt, D., Sharp, H., Hollinshead, J., Mitschang, F., Murphy, P., Nash, R. J. & Wenbourne, J., 3 Aug 2017, In: Tetrahedron. 73, 31, p. 4545-4548

Research output: Contribution to journal › Article › peer-review

Intramolecular epoxide ring opening cyclisation reactions involving guanidines

Al-Shuhaib, Z., Arndt, M., Dennis, M., Evans, D., Jones, I., Leitmann, V., Murphy, P., Roberts, D., Rowles, R., Sadaghiani, Y. K., Thornhill, A. J., Nash, R. J., Hollinshead, J., Bartholomew, B., Tizzard, G. & Coles, S., 16 Feb 2017, In: Tetrahedron. 73, 7, p. 845-852 8 p.

Research output: Contribution to journal › Article › peer-review

Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular Amastigotes

Martins, L. F., Mesquita, J. T., Pinto, E. G., Costa-Silva, T. A., Borborema, S. E. T., Galisteo Junior, A. J., Neves, B. J., Andrade, C. H., Bennett, E., Black, G., Harper, P., Evans, D., Fituri, H., Leyland, J. P., Martin, C., Roberts, T., Thornhill, A. J., Vale, S., Howard-Jones, A., Thomas, D., Williams, H. L., Overman, L., Berlinck, R., Murphy, P. & Tempone, A., 16 Sept 2016, In: Journal of natural products. 79, 9, p. 2202-2210 9 p.

Research output: Contribution to journal › Article › peer-review

Synthesis, applications and mechanistic investigations of C2 Symmetric Guanidinium salts

Allingham, M. T., Bennett, E. L., Davies, D., Harper, P. M., Howard-Jones, A. G., Mehdar, Y. T., Murphy, P. J., Thomas, D., Caulkett, P. W., Potter, D., Lam, C. M. & O'Donoghue, A. C., 28 Jan 2016, In: Tetrahedron. 72, 4, p. 496-503

Research output: Contribution to journal › Article › peer-review

Structure and spectroscopy of CuH prepared via borohydride reduction

Bennett, E. L., Wilson, T., Murphy, P. J., Refson, K., Hannon, A. C., Imberti, S., Callear, S. K., Chass, G. A. & Parker, S. F., 7 Nov 2015, In: Acta Crystallographica Section B. 7, 6, p. 608-612

Research output: Contribution to journal › Article › peer-review

Marine guanidine derivatives affect the redox biology of Leishmania infantum and downregulate cytokines of macrophages

Tempone, A. G., Martins, L. F., Bennett, E. L., Black, G. P. & Murphy, P. J., 1 Nov 2015, In: Planta Medica. 81, 16, p. 1470-1471

Research output: Contribution to journal › Article › peer-review

Anti-parasitic Guanidine and Pyrimidine Alkaloids from the Marine Sponge Monanchora arbuscula

Santos, M. F., Harper, P. M., Williams, D. E., Mesquita, J. T., Pinto, E. G., da Costa-Villa, T. A., Hajdu, E., Ferreira, A. G., Santos, R. A., Murphy, P. J., Anderson, R. J., Tempone, A. G. & Berlinck, R. G., 29 Apr 2015, In: Journal of natural products. 78, 5, p. 1101-1112

Research output: Contribution to journal › Article › peer-review

How the Surface Structure Determines the Properties of CuH

Bennett, E. L., Bennett, E., Wilson, T., Murphy, P. J., Refson, K., Hannon, A. C., Imberti, S., Callear, S. K., Chass, G. A. & Parker, S. F., 11 Feb 2015, In: Inorganic Chemistry. 54, 5, p. 2213-2220

Research output: Contribution to journal › Article › peer-review

Synthetic marine guanidines are effective antileishmanial compounds by altering the plasma membrane permeability

Tempone, A. G., Martins, L. F., Pinto, E. G., Mesquita, J. T., Bennett, E. L., Black, G. P. & Murphy, P. J., 1 Oct 2014, In: Planta Medica. 80, p. 1460

Research output: Contribution to journal › Article › peer-review

Preparation of an ABC tricyclic model of the cylindrospermopsin alkaloids via a biomimetically inspired pathway

Murphy, P. J., Evans, D. M., Horton, P. N. & Hursthouse, M. B., 28 Apr 2014, In: RSC Advances. 4, 40, p. 20744-20751

Research output: Contribution to journal › Article › peer-review

Iodocyclisations reactions of Boc- and Cbz-protected N-allylguanidines

Al-Shuhaib, Z. A., Al Shuhaiba, Z., Davies, D. H., Dennis, M., Evans, D. M., Fletcher, M. D., Franken, H., Hancock, P., Hollinshead, J., Jones, I., Kähm, K., Murphy, P. J., Nash, R. P. & Rowles, R., 15 Apr 2014, In: Tetrahedron. 70, 29, p. 4412-4419

Research output: Contribution to journal › Article › peer-review

Characterization of the hydrides in Stryker's reagent: [HCuP(C 6H5)3]6

Bennett, E. L., Murphy, P. J., Imberti, S. & Parker, S. F., 26 Feb 2014, In: Inorganic Chemistry. 53, 6, p. 2963-2967 5 p.

Research output: Contribution to journal › Article › peer-review

Intramolecular palladium mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines

Al-Shuhaib, Z. A., Doerksen, E., Page, J. M., Al-Shuhaiba, Z., Böckemeier, H., Coghlan, L., Dörksena, E., Jones, I. V., Murphy, P. J. & Nash, R. P., 27 Sept 2013, In: Tetrahedron Letters. 54, 49, p. 6716-6718

Research output: Contribution to journal › Article › peer-review

Self sensitized photooxidation of tetrathienyltetrathiafulvalenes: synthesis of thienyl substituted 1,2,5,8-tetrathiecine-6,7-dione, a new heterocyclic system

Charlton, A., Donati, D., Fusi, S., Murphy, P. J. & Ponticelli, F., 6 Mar 2013, In: Tetrahedron Letters. 54, 10, p. 1227-1229

Research output: Contribution to journal › Article › peer-review

Synthesis and biological activity of analogues of batzelladine F

Vale, S. A., Bennett, E. L., Black, G. P., Brown, P., Hizi, A., Jaffar, M., Leyland, J. P., Martin, C., Oz-Gleenberg, I., Murphy, P. J., Roberts, T. D. & Thornhill, A. J., 6 Feb 2013, In: Tetrahedron. 69, 14, p. 3061-3066

Research output: Contribution to journal › Article › peer-review

Dye-sensitized solar cells (DSSCs) based on poly(3-hexylthioacetate thiophene)

Manji, A. J. & Murphy, P. J., 9 Jan 2013, In: International Journal of Physical Sciences. 8, 1, p. 16-26

Research output: Contribution to journal › Article › peer-review

Triacylglycerol composition of British bluebell (Hyacinthoides non-scripta) seed oil

Thoss, V., Murphy, P. J., Marriott, R. & Wilson, T., 10 Apr 2012, In: RSC Advances. 12, 2, p. 5314-5322

Research output: Contribution to journal › Article › peer-review

A biomimetic approach to the cylindrospermopsin alkaloids

Evans, D. M. & Murphy, P. J., 21 Mar 2011, In: Chemical Communications. 47, 11, p. 3225-3226 2 p.

Research output: Contribution to journal › Article › peer-review

The Cylindrospermopsin Alkaloids

Evans, D. M. & Murphy, P. J., 2011, In: Alkaloids: Chemistry and Biology. 70, p. 1-77 77 p.

Research output: Contribution to journal › Article › peer-review

Iodocyclisation and rearrangement reactions of mono-protected allyl substituted guanidines.

Davies, D., Fletcher, M. D., Franken, H., Hollinshead, J., Kahm, K., Murphy, P. J., Nash, R. & Potter, D. M., 29 Dec 2010, In: Tetrahedron Letters. 51, 52, p. 6825-6829

Research output: Contribution to journal › Article › peer-review

Synthesis and photoreactivity of aryl substituted 4,5-dithienyl[1,3]dithiol-2-ones.

Blencowe, A., Celli, A. M., Donati, D., Hayes, W. C., Martin, C., Murphy, P. J., Ponticelli, F. & Melville-Richards, J. K., 9 May 2009, In: Tetrahedron. 65, 19, p. 3858-3862

Research output: Contribution to journal › Article › peer-review

Electropolymerization Studies on a Series of Thiophene-Substituted 1,3-Dithiole-2-ones: Solid-State Preparation of a Novel TTF-Derivatized Polythiophene.

Anjos, T., Charlton, A., Coles, S. J., Croft, A. K., Hursthouse, M. B., Kalaji, M., Murphy, P. J. & Roberts-Bleming, S. J., 14 Apr 2009, In: Macromolecules. 42, 7, p. 2505-2515

Research output: Contribution to journal › Article › peer-review

Synthesis, structure and spectroscopic properties of a new class of polymerisable nickel dithiolenes

Dalgleish, S., Morrison, C. A., Middlemiss, D. S., Mount, A. R., Collins, A., Pilia, L., Serpe, A., Mercuri, M. L., Roberts-Bleming, S. J., Charlton, A., Deplano, P., Murphy, P. J. & Robertson, N., 1 Jan 2009, In: Journal of Materials Chemistry. 19, 34, p. 6194-6200

Research output: Contribution to journal › Article › peer-review

Cyclisation reactions of bis-protected guanidines.

Albrecht, C., Barnes, S., Bockemeier, H., Davies, D., Dennis, M., Evans, D. M., Fletcher, M. D., Jones, I., Leitmann, V., Murphy, P. J., Rowles, R., Nash, R., Stephenson, R. A., Horton, P. N. & Hursthouse, M. B., 1 Jan 2008, In: Tetrahedron Letters. 49, 1, p. 185-188

Research output: Contribution to journal › Article › peer-review

Nickel dithiolenes containing pendant thiophene units: precursors to dithiolene-polythiophene hybrid materials.

Anjos, T., Roberts-Bleming, S. J., Charlton, A., Robertson, N., Mount, A. R., Coles, S. J., Hursthouse, M. B., Kalaji, M. & Murphy, P. J., 1 Jan 2008, In: Journal of Materials Chemistry. 18, 4, p. 475-483

Research output: Contribution to journal › Article › peer-review

Synthetic studies towards ptilomycalin A: total synthesis of crambescidin 359

Moore, C. G., Murphy, P. J., Williams, H. L., McGown, A. T. & Smith, N. K., 19 Nov 2007, In: Tetrahedron. 63, 47, p. 11771-11780

Research output: Contribution to journal › Article › peer-review

Antimalarial activity of crambescidin 800 and synthetic analogues against liver and blood stage of Plasmodium sp.

Lazaro, J. E., Nitcheu, J., Mahmoudi, N., Ibana, J. A., Mangalindan, G. C., Black, G. P., Howard-Jones, A. G., Moore, C. G., Thomas, D. A., Mazier, D., Ireland, C. M., Concepcion, G. P., Murphy, P. J. & Diquet, B., 1 Oct 2006, In: Journal of Antibiotics. 59, 9, p. 583-590

Research output: Contribution to journal › Article › peer-review

A convenient preparation of (1R, 2S, 7S, 8R)-3,5-diaza-2,7-dimethyl-1,8-diphenyloctan-1,8-diol and its enantiomer

Murphy, P. J., Pinato, S., Thomas, D. & Oller-Lopez, J. L., 1 Sept 2006, In: Chemical and Pharmaceutical Bulletin. 54, 9, p. 1331-1332

Research output: Contribution to journal › Article › peer-review

Synthesis and applications of C2 Symmetric Guanidine Bases.

Allingham, M. T., Howard-Jones, A., Murphy, P. J., Thomas, D. A. & Caulkett, P. W., 24 Nov 2003, In: Tetrahedron Letters. 44, 48, p. 8677-8680

Research output: Contribution to journal › Article › peer-review

Synthesis and Photoreactivity of 4,5-Dithienyl[1,3]dithiol-2-ones.

Robert-Bleming, S. J., Davies, G. L., Kalaji, M., Murphy, P. J., Celli, A. M., Donati, D. & Ponticelli, F., 1 Aug 2003, In: Journal of Organic Chemistry. 68, 18, p. 7115-7118

Research output: Contribution to journal › Article › peer-review

Intramolecular guanidine epoxide ring opening reactions.

Dennis, M., Hall, L. M., Murphy, P. J., Thornhill, A. J., Nash, R., Winters, A. L., Hursthouse, M. B., Light, M. E. & Horton, P., 7 Apr 2003, In: Tetrahedron Letters. 44, 15, p. 3075-3080

Research output: Contribution to journal › Article › peer-review

A synthesis of crambescidin 359.

Moore, C. G., Murphy, P. J., Williams, H. L., McGown, A. T. & Smith, N. K., 6 Jan 2003, In: Tetrahedron Letters. 44, 2, p. 251-254

Research output: Contribution to journal › Article › peer-review

Tandem Michael/Michael reactions mediated by phosphines or aryl thiolates.

Brown, P. M., Kappel, N., Murphy, P. J., Coles, S. J. & Hursthouse, M. B., 25 Nov 2002, In: Tetrahedron. 43, 48, p. 8707-8710

Research output: Contribution to journal › Article › peer-review

Tandem Micheal/Michael reactions mediated by phosphines or aryl thiolates.

Brown, P. M., Kappel, N. & Murphy, P. J., 25 Nov 2002, In: Tetrahedron Letters. 43, 48, p. 8707-8710

Research output: Contribution to journal › Article › peer-review

Ethyl 3-(diphenylphosphinoyl)-3-phenylpropionate.

Light, M. E., Murphy, P. J., Hancock, P. & Hursthouse, M. B., 1 Sept 2002, In: Acta Crystallographica Section E: Structure Reports Online. 58, 9, p. o990-o991

Research output: Contribution to journal › Article › peer-review