1. Article › Research › Peer-reviewed
2. Published

   A Framework for Planning and Critiquing Medication Compliance and Persistence Research Using Prospective Study Designs.

   Hughes, D., Gwadry-Sridhar, F. H., Manias, E., Zhang, Y., Roy, A., Yu-Isenberg, K., Hughes, D. A. & Nichol, M. B., 1 Feb 2009, In: Clinical Therapeutics. 31, 2, p. 421-435

   Research output: Contribution to journal › Article › peer-review

3. Published

   A Fully Integrated Real-Time Detection, Diagnosis, and Control of Community Diarrheal Disease Clusters and Outbreaks (the INTEGRATE Project): Protocol for an Enhanced Surveillance System

   McIntyre, K. M., Bolton, F. J., Christley, R. M., Cleary, P., Deja, E., Durie, A. E., Diggle, P. J., Hughes, D., de Lusignan, S., Orton, L., Radford, A. D., Elliot, A., Smith, G. E., Snape, D. A., Stanistreet, D., Vivancos, R., Winstanley, C. & O'Brien, S. J., 26 Sept 2019, In: JMIR Research Protocols. 8, 9, p. e13941 10 p., e13941.

   Research output: Contribution to journal › Article › peer-review

4. Published

   A Global Survey of Antibiotic Leftovers in the Outpatient Setting.

   Hughes, D., Kardas, P., Pechere, J. C., Hughes, D. A. & Cornaglia, G., 1 Dec 2007, In: International Journal of Antimicrobial Agents. 30, 6, p. 530-536

   Research output: Contribution to journal › Article › peer-review

5. Published

   A Literature Review of GP Knowledge and Understanding of ME/CFS: A Report from the Socioeconomics Working Group of the European Network on ME/CFS (EUROMENE)

   Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., Jan 2021, In: Medicina. 57, 1, 17 p., 7.

   Research output: Contribution to journal › Article › peer-review

6. Published

   A Risk–Benefit Assessment of Prasugrel, Clopidogrel, and Genotype-Guided Therapy in Patients Undergoing Percutaneous Coronary Intervention

   Hughes, D., Guzauskas, G. F., Hughes, D. A., Bradley, S. M. & Veenstra, D. L., 28 Mar 2012, In: Clinical Pharmacology and Therapeutics.

   Research output: Contribution to journal › Article › peer-review

7. E-pub ahead of print

   A framework for understanding sources of bias in medication adherence research

   Sinnappah, K. A., Hughes, D., Stocker, S. L., Vrijens, B., Aronson, J. K. & Wright, D. F. B., 26 Jul 2023, (E-pub ahead of print) In: British Journal of Clinical Pharmacology.

   Research output: Contribution to journal › Article › peer-review

8. Accepted/In press

   A model-based cost-utility analysis of an automated notification system for deteriorating patients on general wards

   Holmes, E., Hughes, D. & Subbe, C., 18 Apr 2024, (Accepted/In press) In: PLoS ONE. PONE-D-23-27466R2.

   Research output: Contribution to journal › Article › peer-review

9. Published

   A new taxonomy for describing and defining adherence to medications

   Holmes, E. A., Hughes, D., Morrison, V. L., Vrijens, B., De Geest, S., Hughes, D. A., Prezemyslaw, K., Demonceau, J., Ruppar, T., Dobbels, F., Fargher, E., Morrison, V., Lewek, P., Matyjaszczyk, M., Mshelia, C., Clyne, W., Aronson, J. K. & Urquhart, J., 1 May 2012, In: British Journal of Clinical Pharmacology. 73, 5, p. 691-705

   Research output: Contribution to journal › Article › peer-review

10. Published

    A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)

    Hughes, D., Ramanan, A., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., Hickey, H., Hughes, D. A., Jones, A., Woo, P., Edelsten, C., Beresford, M. W. & The SYCAMORE Trail Management Group, N. V., 9 Jan 2014, In: Trials. 15, 14

    Research output: Contribution to journal › Article › peer-review

11. Published

    A randomised, patient-assessor blinded, sham-controlled trial of external noninvasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial): study protocol for a randomised controlled trial

    Johnson, S., Goebel, A., Richey, R., Holmes, E. & Hughes, D., 6 Dec 2016, In: Trials. 17, 574.

    Research output: Contribution to journal › Article › peer-review

12. Published

    A systematic review of cost–effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives

    Hughes, D., Verhoef, T. I., Redekop, W. K., Darba, J., Geitona, M., Hughes, D. A., Siebert, U., de Boer, A., Maitland-van der Zee, A. H., Barallon, R., Briz, M., Daly, A., Haschke-Becher, E., Kamali, F., Kirchheiner, J., Manolopoulos, V. G., Pirmohamed, M., Rosendaal, F. R., van Schie, R. M. & Wadelius, M., 1 Jul 2010, In: Pharmacogenomics. 11, 7, p. 989-1002

    Research output: Contribution to journal › Article › peer-review

13. Published

    A systematic review of economic evaluations of pharmacogenetic testing for prevention of adverse drug reactions

    Plumpton, C. O., Roberts, D., Pirmohamed, M. & Hughes, D. A., Aug 2016, In: Pharmacoeconomics. 34, 8, p. 771-793

    Research output: Contribution to journal › Article › peer-review

14. Published

    A systematic review of patients' perspectives on the subcutaneous route of medication administration

    Ridyard, C., Dawoud, D. M., Tuersley, L. V. & Hughes, D., Aug 2016, In: Patient: Patient–Centered Outcomes Research. 9, 4, p. 281-292

    Research output: Contribution to journal › Article › peer-review

15. Published

    A “Bundle of Care” to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study

    Jorgensen, AL., Waitt, C., Orrell, C., Cheng-Hock, T., Sekaggya-Wiltshire, C., Hughes, D., Allen, E., Okello, E., Tatz, G., Culeddu, G., Asiimwe, I. G., Semakula, J. R., Mouton, J. P., Cohen, K., Blockman, M., Lamorde, M. & Pirmohamed, M., 19 Jul 2023, In: Journal of Medical Internet Research. 12, e46710.

    Research output: Contribution to journal › Article › peer-review

16. Published

    Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Nov 2003, In: Value in Health. 6, 6, p. 749

    Research output: Contribution to journal › Article › peer-review

17. Published

    Abolition of prescription charges in Wales: the impact on medicines use in those who used to pay

    Hughes, D., Groves, S., Cohen, D., Alam, M. F., Dunstan, F. D., Routledge, P. A., Hughes, D. A. & Myles, S., 1 Dec 2010, In: International Journal of Pharmacy Practice. 18, 6, p. 332-340

    Research output: Contribution to journal › Article › peer-review

18. Published

    Abolition of prescription copayments in Wales: an observational study on dispensing rates.

    Hughes, D., Cohen, D., Alam, M. F., Dunstan, F. D., Myles, S., Hughes, D. A. & Routledge, P. A., 1 Aug 2010, In: Value in Health. 13, 5, p. 675-680

    Research output: Contribution to journal › Article › peer-review

19. Published

    Acceptability of generic versus innovator oral medicines: not only a matter of taste

    Tuleu, C., Hughes, D., Clapham, D., Vallet, T. & Ruiz, F., Feb 2021, In: Drug Discovery Today. 26, 2, p. 329-343

    Research output: Contribution to journal › Article › peer-review

20. Published

    Accounting for non-compliance in pharmacoeconomic evaluations.

    Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 12, p. 1185-1197

    Research output: Contribution to journal › Article › peer-review

21. Published

    Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam

    Hughes, D., Nov 2020, In: British Journal of Pharmacology. 177, 21, p. 4975-4989 15 p.

    Research output: Contribution to journal › Article › peer-review

22. Published

    Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT

    Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D., McKay, A., Rosala_Hanna, A., Williamson, P. R., Hardwick, B., Hickey, H., Rainford, N., Kolamunnage-Dona, R., Culeddu, G., Plumpton, C., Wood, E., Compeyrot-Lacassagne, S., Woo, P., Eldesten, C. & Beresford, M. W., 10 Apr 2019, In: Health Technology Assessment. 23, 15, p. 1-174 174 p.

    Research output: Contribution to journal › Article › peer-review

23. Published

    Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis

    Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., Hardwick, B., Hickey, H., Hughes, D., Woo, P., Benton, D., Edelsten, C. & Beresford, M. W., 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1637-1646

    Research output: Contribution to journal › Article › peer-review

24. Published

    Adherence and variability in warfarin dose requirements: assessment in a prospective cohort

    Hughes, D., Jorgensen, A. L., Hughes, D. A., Hanson, A., van Eker, D., Toh, C. H., Pirmohamed, M. & Williamson, P. R., 1 Jan 2013, In: Pharmacogenomics. 14, 2, p. 151-163

    Research output: Contribution to journal › Article › peer-review

25. Published

    Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria

    Lotsch, F., Auer-Hackenberg, L., Groger, M., Rehman, K., Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., de Geest, S., Dobbels, F., Vrijens, B., Kardas, P., Hughes, D. & Ramharter, M., May 2015, In: Wiener klinische Wochenschrift. 127, 9-10, p. 379-384

    Research output: Contribution to journal › Article › peer-review

26. Published

    Advanced therapy medicinal products: a comprehensive overview for pharmacy professionals

    McKenzie, C. A., Chappel, J., Guy, R. H., Hawksworth, G., Hughes, D. & Black, A., 12 Aug 2022, In: Pharmaceutical Journal.

    Research output: Contribution to journal › Article › peer-review

27. Published

    Adverse drug reactions in economic evaluations

    Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A109

    Research output: Contribution to journal › Article › peer-review

28. Published

    Adverse drug reactions, multimorbidity and polypharmacy: A prospective analysis of one month of medical admissions

    Osanlou, R., Walker, L., Hughes, D., Burnside, G. & Pirmohamed, M., 4 Jul 2022, In: BMJ Open. 12, 7, e055551.

    Research output: Contribution to journal › Article › peer-review

29. Published

    Affordable orphan drugs: A role for not-for-profit organisations

    Davies, E. H., Fulton, E., Brook, D. & Hughes, D., Jul 2017, In: British Journal of Clinical Pharmacology. 83, 7, p. 1595-1601

    Research output: Contribution to journal › Article › peer-review

30. Published

    An agenda for UK clinical pharmacology Pharmacoeconomics

    Hughes, D. & Hughes, D. A., 1 Jun 2012, In: British Journal of Clinical Pharmacology. 73, 6, p. 968-972

    Research output: Contribution to journal › Article › peer-review

31. Published

    An explanatory randomised controlled trial of a nurse-led, consultation-based intervention to support patients with adherence to taking glucose lowering medication for type 2 diabetes

    Hughes, D., Farmer, A., Hardeman, W., Hughes, D. A., Prevost, A. T., Kim, Y., Craven, A., Oke, J., Boase, S., Selwood, M., Kellar, I., Graffy, J., Griffin, S., Sutton, S. & Kinmonth, A. L., 5 Apr 2012, In: BMC Family Practice. 13, 30

    Research output: Contribution to journal › Article › peer-review

32. Published

    Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multi-centre, single-blinded, randomised trial and economic evaluation

    Mallucci, C. L., Jenkinson, M. D., Conroy, E. J., Hartley, J. C., Brown, M., Dalton, J., Kearns, T., Moitt, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 26 Oct 2019, In: The Lancet. 394, 10208, p. 1530-1539 10 p.

    Research output: Contribution to journal › Article › peer-review

33. Published

    Appropriate design and reporting of superiority, equivalence and non-inferiority clinical trials incorporating a benefit risk assessment: the BRAINS study including expert workshop

    Totton, N., Julious, S., Coates, E., Hughes, D., Cook, J., Biggs, K., Hewitt, C., Day, S. & Cooke, A., Oct 2023, In: Health Technology Assessment. 27, 20, 86 p.

    Research output: Contribution to journal › Article › peer-review

34. Published

    Assessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients

    Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A171

    Research output: Contribution to journal › Article › peer-review

35. E-pub ahead of print

    Best step-up treatments for children with uncontrolled asthma: A systematic review and network meta-analysis of individual participant data

    Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Culeddu, G., Hughes, D., Turner, S. & Tudor-Smith, C., 26 Oct 2023, (E-pub ahead of print) In: European Respiratory Journal.

    Research output: Contribution to journal › Article › peer-review

36. Published

    Between- and within-individual sociodemographic and psychological determinants of PrEP adherence among men who have sex with men prescribed a daily PrEP regimen in Wales

    Gillespie, D., de Bruin, M., Hughes, D., Ma, R., Williams, A., Wood, F., Couzens, Z., Jones, A. T. & Hood, K., May 2023, In: AIDS and Behavior. 27, 5, p. 1564-1572 9 p.

    Research output: Contribution to journal › Article › peer-review

37. Published

    Beyond registration: measuring the public health potential of new treatments for Malaria in Africa.

    Hughes, D., Lang, T., Hughes, D. A., Kanyok, T., Kengeya-Kayondo, J., Marsh, V., Haaland, A., Pirmohamed, M. & Winstanley, P., 1 Jan 2006, In: Lancet Infectious Diseases. 6, 1, p. 46-52

    Research output: Contribution to journal › Article › peer-review

38. Published

    Biological agents for the management of Crohn's disease in adults: A systematic review, meta-analysis and multiples treatment comparison

    Hughes, D., Hughes, D. A., Kikuchi, T. & Bodger, K., 1 Jan 2007, In: Value in Health. 10, 3, p. A147

    Research output: Contribution to journal › Article › peer-review

39. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Mar 2010, In: Clinical Pharmacology and Therapeutics. 87, 3, p. 257-261

    Research output: Contribution to journal › Article › peer-review

40. Published

    CARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial

    Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Feb 2019, In: Trials. 20, 1, 16 p., 105.

    Research output: Contribution to journal › Article › peer-review

41. Published

    CATheter Infections in CHildren (CATCH): a randomised controlled trial and economic evaluation comparing impregnated and standard central venous catheters in children

    Harron, K., Mok, Q., Dwan, K., Ridyard, C., Mott, T., Millar, M., Ramnarayan, P., Tibby, S. M., Muller-Pebody, B., Hughes, D., Gamble, C. & Gilbert, R. E., Mar 2016, In: Health Technology Assessment. 20, 18

    Research output: Contribution to journal › Article › peer-review

42. Published

    Carer administration of as-needed sub-cutaneous medication for breakthrough symptoms in people dying at home: the CARiAD feasibility RCT

    Poolman, M., Roberts, J., Wright, S., Hendry, A., Goulden, N., Holmes, E., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., O'Connor, J., Foster, B., Reymond, L., Healy, S., Lewis, P., Wee, B., Johnstone, R. P., Roberts, R., Parkinson, A., Roberts, S. & Wilkinson, C., 2 Jun 2020, In: Health Technology Assessment. 24, 25, 150 p.

    Research output: Contribution to journal › Article › peer-review

43. Published

    Challenges in the Development and Reimbursement of Personalized Medicine—Payer and Manufacturer Perspectives and Implications for Health Economics and Outcomes Research: A Report of the ISPOR Personalized Medicine Special Interest Group

    Hughes, D., Faulkner, E., Annemans, L., Garrison, L., Helfand, M., Holtorf, A. P., Hornberger, J., Hughes, D. A., Li, T., Malone, D., Payne, K., Siebert, U., Towse, A., Veenstra, D. & Watkins, J., 1 Dec 2012, In: Value in Health. 15, 8, p. 1162-1171

    Research output: Contribution to journal › Article › peer-review

44. Published

    Changing Agendas on Sleep, Treatment and Learning in Epilepsy (CASTLE) Sleep-E: A protocol for a randomised controlled trial comparing an online behavioural sleep intervention with standard care in children with Rolandic epilepsy

    Al-Najjar, N., Bray, L., Carter, B., Collingwood, A., Cook, G., Crudgington, H., Dietz, K., Hardy, W., Hiscock, H., Hughes, D., Morris, C., Rouncefield-Swales, A., Saron, H., Spowart, C., Stibbs-Easton, L., Tudur Smith, C., Watson, V., Whittle, L., Wiggs, L., Wood, E., Gringas, P. & Pal, D. K., 10 Mar 2023, In: BMJ Open. 13, 3, e065769.

    Research output: Contribution to journal › Article › peer-review

45. Published

    Charitable contributions to funding cancer services for children and young people in England and Wales

    Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2008, In: Journal of Child Health Care. 12, 2, p. 156-168

    Research output: Contribution to journal › Article › peer-review

46. Published

    Chiral chromatography: Costs of chiral switching.

    Hughes, D. & Hughes, D. A., 1 Jan 2008, In: Pharmaceutical Journal. 281, p. 213

    Research output: Contribution to journal › Article › peer-review

47. Published

    Choice of oral anticoagulant prescribed by general practices in Wales: Application of Dirichlet regression and linked data

    Hill-McManus, D. & Hughes, D., Jun 2022, In: British Journal of Clinical Pharmacology. 88, 6, p. 2782-2792 11 p.

    Research output: Contribution to journal › Article › peer-review

48. Published

    Cisplatin plus vinorelbine or gemcitabine in patients with advanced non-small cell lung cancer: Pharmacoeconomic considerations.

    Hughes, D. & Hughes, D. A., 1 Jul 2005, In: European Journal of Cancer. 41, 11, p. 1655

    Research output: Contribution to journal › Article › peer-review

49. Published

    Climate influences on the cost-effectiveness of vector-based interventions against malaria in elimination scenarios

    Hughes, D., Parham, P. E. & Hughes, D. A., 16 Feb 2015, In: Philosophical Transactions B: Biological Sciences. 370, 1665

    Research output: Contribution to journal › Article › peer-review

50. Published

    Clinical Pharmacology: Special safety considerations in drug development and pharmacovigilance.

    Hughes, D., Atuah, K. N., Hughes, D. A. & Pirmohamed, M., 1 Jan 2004, In: Drug Safety. 27, 8, p. 535-554

    Research output: Contribution to journal › Article › peer-review

51. Published

    Clinical interventions to improve adherence to urate-lowering therapy in patients with gout: a systematic review

    Sinnappah, K. A., Stocker, S. L., Chan, J. S., Hughes, D. A. & Wright, D. F. B., 25 Jun 2022, In: International Journal of Pharmacy Practice. 30, 3, p. 215-225 11 p.

    Research output: Contribution to journal › Article › peer-review

52. Published

    Combining model-based clinical trial simulation, pharmacoeconomics and value of information to optimize trial design

    Hill-McManus, D. & Hughes, D., Jan 2021, In: CPT: Pharmacometrics & Systems Pharmacology . 10, 1, p. 75-83 9 p.

    Research output: Contribution to journal › Article › peer-review

53. Published

    Community views on factors affecting medicines resource allocation: Cross-sectional survey of 3080 adults in Australia

    Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 2019, In: Australian Health Review . 43, 3, p. 254-260

    Research output: Contribution to journal › Article › peer-review

54. Published

    Comparative Effectiveness of Dabigatran, Rivaroxaban, Apixaban, and Warfarin in the Management of Patients With Nonvalvular Atrial Fibrillation

    Hughes, D., Pink, J., Pirmohamed, M. & Hughes, D. A., 25 Apr 2013, In: Clinical Pharmacology and Therapeutics.

    Research output: Contribution to journal › Article › peer-review

55. Published

    Conducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches

    Hughes, D., Charles, J. M., Dawoud, D. M., Edwards, R. T., Holmes, E. A., Jones, C. L., Parham, P., Plumpton, C., Ridyard, C. O., Lloyd-Williams, H., Wood, E. M. & Yeo, S., May 2016, In: Pharmacoeconomics. 34, 5, p. 447-461

    Research output: Contribution to journal › Article › peer-review

56. Published

    Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey

    Thorn, J., Davies, C. F., Brookes, S., Noble, S., Dritsaki, M., Gray, E., Hughes, D., Mihaylova, B., Petrou, S., Ridyard, C., Sach, T., Wilson, E., Wordsworth, S. & Hollingworth, W., 1 Apr 2021, In: Value in Health. 24, 4, p. 539-547 9 p.

    Research output: Contribution to journal › Article › peer-review

57. Published

    Continuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis

    Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A582

    Research output: Contribution to journal › Article › peer-review

58. Published

    Continuous subcutaneous insulin infusion versus multiple daily injection regimens in children and young people at diagnosis of type 1 diabetes: pragmatic randomised controlled trial and economic evaluation

    Blair, J. C., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. A. & Gamble, C., 3 Apr 2019, In: British Medical Journal. 365, p. l1226 l1226.

    Research output: Contribution to journal › Article › peer-review

59. Published

    Continuous subcutaneous insulin infusion versus multiple daily injections in children and young people at diagnosis of type 1 diabetes: the SCIPI RCT

    Blair, J., McKay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., Gregory, J. W., Hughes, D. & Gamble, C., Aug 2018, In: Health Technology Assessment. 22, 42, p. 1-112 112 p.

    Research output: Contribution to journal › Article › peer-review

60. Published

    Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus

    Crudgington, H., Rogers, M., Bray, L., Carter, B., Currier, J., Gibbon, F., Hughes, D., Lyle, S., Roberts, D., Smith, C. T., Gringras, P., Pal, D. & Morris, C., May 2019, In: Epilepsia. 60, 5, p. 857-871

    Research output: Contribution to journal › Article › peer-review

61. Published

    Core items for a standardized resource-use measure (ISRUM): expert Delphi consensus survey

    Thom, J., Brookes, S. T., Ridyard, C., Riley, R., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., Jun 2018, In: Value in Health. 21, 6, p. 640-649

    Research output: Contribution to journal › Article › peer-review

62. Published

    Cost and clinical consequence of antibiotic non-adherence in acute exacerbations of chronic bronchitis.

    Sorensen, S. V., Baker, T., Fleurence, R., Dixon, J., Roberts, C., Haider, S. & Hughes, D., 1 Aug 2009, In: International Journal of Tuberculosis and Lung Disease. 13, 8, p. 945-954

    Research output: Contribution to journal › Article › peer-review

63. Published

    Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout

    Plumpton, C., Alfirevic, A., Pirmohamed, M. & Hughes, D., 1 Oct 2017, In: Rheumatology. 56, 10, p. 1729-1739

    Research output: Contribution to journal › Article › peer-review

64. Published

    Cost effectiveness of pharmacogenetic screening prior to initiation of carbamazepine treatment for epilepsy

    Plumpton, C. O., Yip, V., Alfirevic, A., Marson, A., Pirmohamed, M. & Hughes, D., Nov 2013, In: Value in Health. 16, 7, p. A624-A624

    Research output: Contribution to journal › Article › peer-review

65. Published

    Cost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease

    Hughes, D. & Hughes, D. A., 1 Nov 2004, In: Value in Health. 7, 6, p. 753

    Research output: Contribution to journal › Article › peer-review

66. Published

    Cost minimization of on-demand maintenance therapy with proton pump inhibitors in nonerosive gastroesophageal reflux disease.

    Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Feb 2005, In: Expert Review of Pharmacoeconomics and Outcomes Research. 5, 1, p. 29-38

    Research output: Contribution to journal › Article › peer-review

67. Published

    Cost-Effectiveness Analysis of the Use of Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing in Primary Care

    Holmes, E., Harris, S. D., Hughes, A., Craine, N. & Hughes, D., 7 Dec 2018, In: Antibiotics. 7, 4, 19 p., 106.

    Research output: Contribution to journal › Article › peer-review

68. Published

    Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation

    Hughes, D., Pink, J., Pirmohamed, M., Lane, S. & Hughes, D. A., 23 Sept 2013, In: Clinical Pharmacology and Therapeutics.

    Research output: Contribution to journal › Article › peer-review

69. Published

    Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity

    Hughes, D., Hughes, D. A., Vilar, F. J., Ward, C. C., Alfirevic, A., Park, B. K. & Pirmohamed, M., 1 Jun 2004, In: Pharmacogenetics. 14, 6, p. 335-342

    Research output: Contribution to journal › Article › peer-review

70. Published

    Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis

    Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. 415-424

    Research output: Contribution to journal › Article › peer-review

71. Published

    Cost-effectiveness analysis of extended-release formulations of oxybutynin and tolterodine for the management of urge incontinence.

    Hughes, D., Hughes, D. A. & Dubois, D., 1 Jan 2004, In: Pharmacoeconomics. 22, 16, p. 1047-1059

    Research output: Contribution to journal › Article › peer-review

72. Published

    Cost-effectiveness of biological therapy for Crohn's disease: Markov cohort analyses incorporating United Kingdom patient-level cost data.

    Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Aug 2009, In: Alimentary Pharmacology and Therapeutics. 30, 3, p. 265-274

    Research output: Contribution to journal › Article › peer-review

73. Published

    Cost-effectiveness of home versus hospital management of children at onset of Type 1 Diabetes: The DECIDE randomised controlled trial

    McCarroll, Z., Townson, J., Pickles, T., Gregory, J. W., Playle, R., Robling, M. & Hughes, D., 19 May 2021, In: BMJ Open. 11, 5, e043523.

    Research output: Contribution to journal › Article › peer-review

74. Published

    Cost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial

    Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Sept 2017, In: Frontiers in Pharmacology. 8, 644.

    Research output: Contribution to journal › Article › peer-review

75. Published

    Cost-effectiveness of panel tests for multiple pharmacogenes associated with adverse drug reactions: An evaluation framework

    Plumpton, C., Pirmohamed, M. & Hughes, D., Jun 2019, In: Clinical Pharmacology and Therapeutics. 105, 6, p. 1429-1438

    Research output: Contribution to journal › Article › peer-review

76. Published

    Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden

    Verhoef, T. I., Redekop, W. K., Langenskiold, S., Kamali, F., Wadelius, M., Burnside, G., Maitland-van der Zee, A. H., Hughes, D. & Pirmohamed, M., Oct 2016, In: The Pharmacogenomics Journal. 16, p. 478–484

    Research output: Contribution to journal › Article › peer-review

77. Published

    Cost-effectiveness of screening for HLA-A*31:01 prior to initiation of carbamazepine in epilepsy

    Plumpton, C., Yip, V. L. M., Alfirevic, A., Marson, A. G., Pirmohamed, M. & Hughes, D., Apr 2015, In: Epilepsia.

    Research output: Contribution to journal › Article › peer-review

78. Published

    Cost-utility analysis of on demand rabeprazole and esomeprazole for symptomatic gastro oesophageal reflux disease

    Hughes, D., Hughes, D. A. & Dubois, D., 1 Nov 2003, In: Value in Health. 6, 6, p. 613

    Research output: Contribution to journal › Article › peer-review

79. Published

    Costs of Medication Nonadherence in Patients with Diabetes Mellitus: A Systematic Review and Critical Analysis of the Literature.

    Hughes, D., Salas, M., Hughes, D. A., Zuluaga, A., Vardeva, K. & Lebmeier, M., 1 Sept 2009, In: Value in Health. 12, 6, p. 915-922

    Research output: Contribution to journal › Article › peer-review

80. Published

    Costs of orphan medicinal products: longitudinal analysis of expenditure in Wales

    Pijeira Perez, Y., Wood, E. & Hughes, D., 1 Nov 2023, In: Orphanet Journal of Rare Diseases. 18, 1, 342.

    Research output: Contribution to journal › Article › peer-review

81. Published

    Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

    Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417

    Research output: Contribution to journal › Article › peer-review

82. Published

    Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

    Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Aug 2007, In: Clinical Pharmacology and Therapeutics. 82, 2, p. 123-127

    Research output: Contribution to journal › Article › peer-review

83. Published

    Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses

    Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., N. V., 31 Oct 2011, In: British Medical Journal. 343, p. 1-14

    Research output: Contribution to journal › Article › peer-review

84. Published

    Decision analytic modelling methods for the assessing the effectiveness of treatment sequences for clinical and economic decision making: a methodological review

    Lewis, R., Hughes, D. & Wilkinson, C., 30 Nov 2017, In: Value in Health. 20, 9, p. A748 1 p.

    Research output: Contribution to journal › Article › peer-review

85. Published

    Decision-Makers’ Preferences for Approving New Medicines in Wales: A Discrete-Choice Experiment with Assessment of External Validity

    Hughes, D., Linley, W. G. & Hughes, D. A., 1 Apr 2013, In: Pharmacoeconomics. 31, 4, p. 345-355

    Research output: Contribution to journal › Article › peer-review

86. Published

    Defining rewardable innovation in drug therapy

    Hughes, D., Aronson, J. K., Ferner, R. E. & Hughes, D. A., 1 Apr 2012, In: Nature Reviews Drug Discovery. 11, p. 253-254

    Research output: Contribution to journal › Article › peer-review

87. Published

    Developing an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project

    Holmes, E., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Foster, D., Hardman, K., Bell, S., Marson, A., Hughes, D. & Noble, A. J., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 28-37

    Research output: Contribution to journal › Article › peer-review

88. Accepted/In press

    Developing feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed methods study

    Noble, A. J., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., McKinlay, A., Dickson, J., Goodacre, S., Jackson, M., Morris, B., Hughes, D., Marson, T. & Holmes, E., 6 Jun 2023, (Accepted/In press) In: Health Services and Delivery Research (HS&DR).

    Research output: Contribution to journal › Article › peer-review

89. Published

    Developing patient-centred, feasible alternative care for adult emergency department users with epilepsy: Protocol for the mixed-methods observational ‘Collaborate’ project.

    Noble, A. J., Mathieson, A., Ridsdale, L., Holmes, E., Morgan, M., McKinlay, A., Dickson, J., Jackson, M., Hughes, D., Goodacre, S. & Marson, A. G., 2 Nov 2019, In: BMJ Open. 9, 11, e031696.

    Research output: Contribution to journal › Article › peer-review

90. Published

    Development of a Database of Instruments for Resource-Use Measurement: Purpose, Feasibility, and Design

    DIRUM Team, 1 Jul 2012, In: Value in Health. 15, 5, p. 650-655

    Research output: Contribution to journal › Article › peer-review

91. Published

    Does Electronic Monitoring Influence Adherence to Medication? Randomized Controlled Trial of Measurement Reactivity

    Hughes, D., Sutton, S., Kinmonth, A. L., Hardeman, W., Hughes, D. A., Boase, S., Prevost, T., Kellar, I., Graffy, J., Griffin, S. & Farmer, A., 1 Dec 2014, In: Annals of Behavioral Medicine. 48, 3, p. 293-299

    Research output: Contribution to journal › Article › peer-review

92. Published

    Drugs for exceptionally rare diseases: do they deserve special status for funding?

    Hughes, D., Tunnage, B. & Yeo, S. T., 1 Nov 2005, In: QJM - An International Journal of Medicine. 98, 11, p. 829-836

    Research output: Contribution to journal › Article › peer-review

93. Published

    ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

    De Geest, S., Zullig, L. L., Dunbar-Jacob, J., Helmy, R., Hughes, D., Wilson, I. & Vrijens, B., 3 Jul 2018, In: Annals of Internal Medicine. 169, 1, p. 30-35

    Research output: Contribution to journal › Article › peer-review

94. Published

    Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales

    Gillespie, D., Knapper, C., Hughes, D., Couzen, Z., Wood, F., de Bruin, M., Ma, R., Jones, A. T., Williams, A. & Hood, K., 17 Feb 2021, In: Sexually transmitted infections. 97, 2, p. 85-87 3 p., 054598.

    Research output: Contribution to journal › Article › peer-review

95. Published

    Economic Studies in Motor Neurone Disease: A Systematic Methodological Review

    Moore, A., Young, C. A. & Hughes, D., Apr 2017, In: Pharmacoeconomics. 35, 4, p. 397-413

    Research output: Contribution to journal › Article › peer-review

96. Published

    Economic analysis of on-demand maintenance therapy with proton pump inhibitors in patients with non-erosive reflux disease.

    Hughes, D., Hughes, D. A., Bodger, K., Bytzer, P., De Herdt, D. & Dubois, D., 1 Jan 2005, In: Pharmacoeconomics. 23, 10, p. 1031-1041

    Research output: Contribution to journal › Article › peer-review

97. Published

    Economic evaluation of a behavior-modifying intervention to enhance antiepileptic drug adherence

    Hughes, D., Plumpton, C. O., Brown, I., Reuber, M., Marson, A. G. & Hughes, D. A., 26 Mar 2015, In: Epilepsy and Behavior. 45, p. 180-186

    Research output: Contribution to journal › Article › peer-review

98. Published

    Economic evaluations during early (Phase II) drug development: A role for clinical trial simulations.

    Hughes, D., Hughes, D. A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 11, p. 1069-1077

    Research output: Contribution to journal › Article › peer-review

99. Published

    Economic impact of poor compliance with pharmaceuticals.

    Hughes, D. & Hughes, D. A., 1 Aug 2002, In: Expert Review of Pharmacoeconomics and Outcomes Research. 2, 4, p. 327-335

    Research output: Contribution to journal › Article › peer-review

100. Published

     Economics of pharmacogenetic guided treatments: Underwhelming or overstated?

     Hughes, D., May 2018, In: Clinical Pharmacology and Therapeutics. 103, 5, p. 749-751

     Research output: Contribution to journal › Article › peer-review

101. Published

     Effectiveness of out-patient based acute heart failure care: A pilot randomised controlled trial

     Wong, K. Y. K., Hughes, D., Debski, M., Latt, N., Assaf, O., Abdelrahman, A., Taylor, R., Allgar, V., McNeill, L., Howard, S., Wong, S. Y. S., Jones, R., Cassidy, C. J., Seed, A., Galasko, G., Clark, A., Davis, G. K., Montasem, A., Lang, C. C., Kalra, P. R., Campbell, R., Lip, G. Y. H. & Cleland, J. G. F., Oct 2023, In: Acta Cardiologica. 78, 7, p. 828-837 10 p.

     Research output: Contribution to journal › Article › peer-review

102. Published

     Effects of the abolition of prescription charges in Wales: a preliminary analysis.

     Hughes, D., Cohen, D., Alam, M. F., Hughes, D. A., Dunstan, F. & Routledge, P., 1 Jan 2008, In: International Journal of Pharmacy Practice. 16, Supplement 1, p. A39

     Research output: Contribution to journal › Article › peer-review

103. Published

     EstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): Protocol for a systematic review, network meta-analysis and cost-effectiveness analysis using individual participant data (IPD)

     Cividini, S., Sinha, I., Donegan, S., Maden, M., Culeddu, G., Rose, K., Fulton, O., Hughes, D., Turner, S. & Smith, C. T., 5 Feb 2021, In: BMJ Open. 11, e040528.

     Research output: Contribution to journal › Article › peer-review

104. Published

     Estimating Drug Costs in Economic Evaluations in Ireland and the UK: An Analysis of Practice and Research Recommendations.

     Hughes, D., Hughes, D. A., Tilson, L. & Drummond, M. F., 1 May 2009, In: Pharmacoeconomics. 27, 8, p. 635-643

     Research output: Contribution to journal › Article › peer-review

105. Published

     Estimation of the impact of noncompliance on pharmacokinetics: an analysis of the influence of dosing regimens

     Hughes, D. & Hughes, D. A., 1 Dec 2008, In: British Journal of Clinical Pharmacology. 65, 6, p. 871-878

     Research output: Contribution to journal › Article › peer-review

106. Published

     Evaluation of a consultant audit and feedback programme to improve the quality of antimicrobial prescribing in acute medical admissions

     Hughes, D., Roberts, E., Dawoud, D. M., Hughes, D. A. & Cefai, C., 1 Oct 2015, In: International Journal of Pharmacy Practice. 23, 5, p. 333-339

     Research output: Contribution to journal › Article › peer-review

107. Published

     Experiences of men who have sex with men when initiating, implementing, and persisting with HIV pre-exposure prophylaxis

     Gillespie, D., Wood, F., Williams, A., Ma, R., de Bruin, M., Hughes, D., Jones, A. T., Couzens, Z. & Hood, K., Aug 2022, In: Health Expectations. 25, 4, p. 1332-1341 10 p.

     Research output: Contribution to journal › Article › peer-review

108. Published

     Extended-release pharmacotherapy for opioid use disorder (EXPO): protocol for an open-label randomised controlled trial of the effectiveness and cost-effectiveness of injectable buprenorphine versus sublingual tablet buprenorphine and oral liquid methadone

     Marsden, J., Kelleher, M., Hoare, Z., Hughes, D., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Scott, G., Turner, S., Vanderwaal, R., Wareham, A., Gilvarry, E. & Mitcheson, L., 19 Aug 2022, In: Trials. 23, 1, 697.

     Research output: Contribution to journal › Article › peer-review

109. Published

     Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment

     Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 Jan 2007, In: Value in Health. 10, 3, p. A23

     Research output: Contribution to journal › Article › peer-review

110. Published

     Feasibility, validity and reliability of the Welsh version of the EQ-5D health status questionnaire.

     Hughes, D. & Hughes, D. A., 1 Oct 2007, In: Quality of Life Research. 16, 8, p. 1419-1423

     Research output: Contribution to journal › Article › peer-review

111. Published

     Feasibility, validity, and reliability of the Welsh version of the EQ-5D health status questionnaire

     Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A189

     Research output: Contribution to journal › Article › peer-review

112. Published

     Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial.

     Russell, I. T., Slegg, G. P., Roberts, S. H., Bedson, E., Hughes, D., Lloyd, K., Moat, S., Pirmohamed, M., Slegg, G., Tranter, R., Whitaker, R., Wilkinson, C. & Russell, I., 15 Nov 2007, In: BMC Psychiatry. 7, 1, p. 65

     Research output: Contribution to journal › Article › peer-review

113. Published

     Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation

     Bedson, E., Bell, D., Carr, D., Carter, B., Hughes, D., Jorgensen, A., Lewis, H., Lloyd, K., McCaddon, A., Moat, S., Pink, J., Pirmohamed, M., Roberts, S., Russell, I., Sylvestre, Y., Tranter, R., Whitaker, R., Wilkinson, C. & Williams, N., Jul 2014, In: Health Technology Assessment. 18, 48, p. 1-159

     Research output: Contribution to journal › Article › peer-review

114. Published

     Follow-up of cancer in primary care versus secondary care: systematic review

     Lewis, R. A., Neal, R. D., Williams, N. H., France, B., Hendry, M., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., 1 Jul 2009, In: British Journal of General Practice. 59, 564, p. e234-e247

     Research output: Contribution to journal › Article › peer-review

115. Published

     From NCE to NICE: the role of pharmacoeconomics

     Hughes, D. & Hughes, D. A., 1 Sept 2010, In: British Journal of Clinical Pharmacology. 70, 3, p. 317-319

     Research output: Contribution to journal › Article › peer-review

116. Published

     Generalisability and Cost-Impact of Antibiotic-Impregnated Central Venous Catheters for Reducing Risk of Bloodstream Infection in Paediatric Intensive Care Units in England

     Harron, K., Mok, Q., Hughes, D., Muller-Pebody, B., Parslow, R., Ramnarayan, P. & Gilbert, R., 21 Mar 2016, In: PLoS ONE. 11, 3, p. e0151348

     Research output: Contribution to journal › Article › peer-review

117. Published

     Generic and therapeutic substitutions in the UK: are they a good thing?

     Hughes, D., Duerden, M. G. & Hughes, D. A., 1 Sept 2010, In: British Journal of Clinical Pharmacology. 70, 3, p. 335-341

     Research output: Contribution to journal › Article › peer-review

118. Published

     Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.

     Hughes, D., Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., Van Eker, D., Stevens, L., Hawkins, K., Toh, C. H., Kamali, F., Daly, A. K., Fitzmaurice, D., Coffey, A., Williamson, P. R., Park, B. K., Deloukas, P. & Pirmohamed, M., 1 Oct 2009, In: Pharmacogenetics and Genomics. 19, 10, p. 800-812

     Research output: Contribution to journal › Article › peer-review

119. Published

     HLA-B*5701 and abacavir hypersensitivity - Reply.

     Hughes, D., Hughes, D. A., Park, B. K. & Pirmohamed, M., 1 Nov 2004, In: Pharmacogenetics. 14, 11, p. 784

     Research output: Contribution to journal › Article › peer-review

120. Published

     HTAs and rare diseases: How to assess their cost-effectiveness

     Hughes, D., Phillips, C. J. & Hughes, D. A., 1 Nov 2011, In: Pharmaceuticals Policy and Law. 13, 3-4, p. 161-165

     Research output: Contribution to journal › Article › peer-review

121. Published

     Health utilities and costs for Motor Neurone Disease

     Moore, A., Young, C. A. & Hughes, D., Nov 2019, In: Value in Health. 22, 11, p. 1257-1265

     Research output: Contribution to journal › Article › peer-review

122. Published

     Health utilities and costs for neuromyelitis optica spectrum disorder

     Hughes, D., Bourke, S., Jones, A., Bhatt, R., Huda, S., Mutch, K. & Jacob, A., 2022, In: Orphanet Journal of Rare Diseases. 17, 11 p., 159.

     Research output: Contribution to journal › Article › peer-review

123. Published

     Health utilities and quality-adjusted life years for patients with amyotrophic lateral sclerosis receiving reldesemtiv or placebo in FORTITUDE-ALS

     Gebrehiwet, P., Meng, L., Saroccoa, P., Wei, J., Wolff, A. A., Butzner, M., Chio, A., Andrews, J. A., Genge, A., Hughes, D., Jackson, C. E., Lechtzin, N., Miller, T. M. & Shefner, J. M., 31 Mar 2023, In: Journal of Medical Economics. 26, 1, p. 488-493 6 p.

     Research output: Contribution to journal › Article › peer-review

124. Published

     Identification and Assessment of Adherence-Enhancing Interventions in Studies Assessing Medication Adherence Through Electronically Compiled Drug Dosing Histories: A Systematic Literature Review and Meta-Analysis

     Hughes, D., Holmes, E. A., Demonceau, J., Ruppar, T., Kristano, P., Hughes, A. D., Fargher, E., Przemyslaw, K., De Geest, S., Dobbels, F., Lewek, P., Urquhart, J. & Vrijens, B., 1 May 2013, In: Drugs. 73, 6, p. 545-562

     Research output: Contribution to journal › Article › peer-review

125. Published

     Impact of Interventions on Medication Adherence and Blood Pressure Control in Patients with Essential Hypertension: A Systematic Review by the ISPOR Medication Adherence and Persistence Special Interest Group

     Hughes, D., Gwadry-Sridhar, F. H., Manias, E., Lal, L., Salas, M., Hughes, D. A., Ratzki-Leewing, A. & Grubisic, M., 1 Jul 2013, In: Value in Health. 16, 5, p. 863-871

     Research output: Contribution to journal › Article › peer-review

126. Published

     Impact of non-adherence and flare resolution on the cost effectiveness of treatments for gout: Application of a linked pharmacometric/pharmacoeconomic model

     Hill-McManus, D., Marshall, S., Soto, E., Lane, S. & Hughes, D., Dec 2018, In: Value in Health. 21, 12, p. 1373-1381

     Research output: Contribution to journal › Article › peer-review

127. Published

     Impact of non-adherence on the safety and efficacy of uric acid lowering therapies in the treatment of gout

     Hill McManus, D., Soto, E., Marshall, S., Lane, S. & Hughes, D., Jan 2018, In: British Journal of Clinical Pharmacology. 84, 1, p. 142-152

     Research output: Contribution to journal › Article › peer-review

128. Published

     Impact of non-compliance on the cost-effectiveness of statin therapy

     Hughes, D., Hughes, D. A. & Bagust, A., 1 Sept 2001, In: Value in Health. 4, 6, p. 489

     Research output: Contribution to journal › Article › peer-review

129. Published

     Impact of relaxing Covid-19 social distancing measures on rural North Wales: a simulation analysis

     Hughes, R. P. & Hughes, D., 14 Dec 2020, In: Frontiers in Public Health. 8, 562473.

     Research output: Contribution to journal › Article › peer-review

130. Published

     Impact on the phased abolition of co-payments on the utilisation of selected prescription medicines in Wales

     Alam, M. F., Cohen, D., Dunstan, F., Hughes, D. & Routledge, P. A., Jan 2018, In: Health Economics. 27, 1, p. 236-243

     Research output: Contribution to journal › Article › peer-review

131. Published

     Impregnated central venous catheters for prevention of bloodstream infection in children (the CATCH trial): a randomised controlled trial

     Gilbert, R. E., Mok, Q., Dwan, K., Harron, K., Moitt, T., Millar, M., Ramnarayan, P., Tibby, S. M., Hughes, D. & Gamble, C. F., 23 Apr 2016, In: The Lancet. 387, 10029, p. 1732-1742

     Research output: Contribution to journal › Article › peer-review

132. Published

     Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care

     Swift, B., Jain, L., White, C., Chandrasekaran, V., Bhandari, A., Hughes, D. & Jadhav, P., Sept 2018, In: Clinical and Translational Science. 11, 5, p. 450-460 11 p.

     Research output: Contribution to journal › Article › peer-review

133. Published

     Integration of Pharmacometrics and Pharmacoeconomics to Quantify the Value of Improved Forgiveness to Nonadherence: A Case Study of Novel Xanthine Oxidase Inhibitors for Gout

     Hill McManus, D., Marshall, S., Soto, E. & Hughes, D., Sept 2019, In: Clinical Pharmacology and Therapeutics. 106, 3, p. 652-660

     Research output: Contribution to journal › Article › peer-review

134. Published

     Interventions to improve osteoporosis medication adherence and persistence: a systematic review and literature appraisal by the ISPOR Medication Adherence & Persistence Special Interest Group

     Hughes, D., Linck, P. G., Hiligsmann, M., Salas, M., Hughes, D. A., Manias, E., Gwadry-Sridhar, F. H., Linck, P. & Cowell, W., 1 Dec 2013, In: Osteoporosis International. 24, 12, p. 2907-2918

     Research output: Contribution to journal › Article › peer-review

135. Published

     Is exercise effective in promoting mental well-being in older age? A systematic review.

     Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Aug 2010, In: Aging and Mental Health. 14, 6, p. 652-669

     Research output: Contribution to journal › Article › peer-review

136. Published

     Is there a role for Natural Desiccated Thyroid in the treatment of levothyroxine unresponsive hypothyroidism? Results from a Consecutive Case Series

     Heald, A., Premawardhana, L., Taylor, P., Okosieme, O., Bangi, T., Devine, H., Livingston, M., Javed, A., Moreno, G. Y. C., Watt, T., Stedman, M. & Hughes, D., 28 Dec 2021, In: International Journal of Clinical Practice. 75, 12, e14967.

     Research output: Contribution to journal › Article › peer-review

137. Published

     Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs

     Marson, A. G., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P. R., Baker, G., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., Dec 2021, In: Health Technology Assessment. 25, 75, 162 p.

     Research output: Contribution to journal › Article › peer-review

138. Published

     Less is more: Medicines that require less frequent administration improve adherence, but are they better?

     Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 3, p. 211-213

     Research output: Contribution to journal › Article › peer-review

139. Published

     Lessons learnt from a discontinued randomised controlled trial: Adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC)

     Williams, N., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Jul 2018, In: Trials. 19, 408.

     Research output: Contribution to journal › Article › peer-review

140. Published

     Linked Pharmacometric-Pharmacoeconomic Modeling and Simulation in Clinical Drug Development

     Hill-McManus, D., Marshall, S., Liu, J., Willke, R. & Hughes, D., Jul 2021, In: Clinical Pharmacology and Therapeutics. 110, 1, p. 49-63

     Research output: Contribution to journal › Article › peer-review

141. Published

     Liothyronine for hypothyroidism: A candidate for disinvestment or in need of further research? A value of information analysis

     Hughes, D., Skiadas, K., Fitzsimmons, D., Anderson, P. & Heald, A., 3 Dec 2021, In: BMJ Open. 11, 12, e051702.

     Research output: Contribution to journal › Article › peer-review

142. Published

     Managing Access to Advanced Therapy Medicinal Products: Challenges for NHS Wales

     Champion, A. R., Lewis, S., Davies, S. & Hughes, D., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2444-2449

     Research output: Contribution to journal › Article › peer-review

143. Published

     Mapping ALSFRS-R and ALSUI to EQ-5D in patients with motor neurone disease

     Moore, A., Young, C. A. & Hughes, D., Nov 2018, In: Value in Health. 21, 11, p. 1322-1329

     Research output: Contribution to journal › Article › peer-review

144. Published

     Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi.

     Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Hughes, D. A., Molyneux, M. E., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 26 Aug 2009, In: Malaria Journal. 8, p. 204

     Research output: Contribution to journal › Article › peer-review

145. Published

     Mechanism-Based Approach to the Economic Evaluation of Pharmaceuticals: Pharmacokinetic/Pharmacodynamic/Pharmacoeconomic Analysis of Rituximab for Follicular Lymphoma.

     Hughes, D., Pink, J., Lane, S. & Hughes, D. A., 19 Mar 2012, In: Pharmacoeconomics.

     Research output: Contribution to journal › Article › peer-review

146. Published

     Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial

     Johnson, S., Marshall, A., Hughes, D., Holmes, E., Henrich, F., Nurmikko, T., Sharma, M., Frank, B., Bassett, P., Marshall, A. & Goebel, A., 6 Nov 2021, In: Journal of Translational Medicine. 19, 1, 458.

     Research output: Contribution to journal › Article › peer-review

147. Published

     Medicines concordance and game theory.

     Hughes, D. & Hughes, D. A., 1 Oct 2008, In: British Journal of Clinical Pharmacology. 66, 4, p. 577

     Research output: Contribution to journal › Article › peer-review

148. Published

     Methodological Issues in the literature on costs of non-compliance in chronic diseases.

     Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008, In: Value in Health. 11, 6, p. A571-A572

     Research output: Contribution to journal › Article › peer-review

149. Published

     Methodological considerations on estimating medication adherence from self-report, electronic monitoring, and electronic healthcare databases using the TEOS framework

     Dima, A. L., Allemann, S. S., Dunbar-Jacob, J., Hughes, D., Vrijens, B. & Wilson, I., Jul 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 1918-1927

     Research output: Contribution to journal › Article › peer-review

150. Published

     Methods for Extrapolating Survival Analyses for the Economic Evaluation of Advanced Therapy Medicinal Products

     Hardy, W. & Hughes, D., 16 Sept 2022, In: Human Gene Therapy. 33, 17-18, p. 845-856

     Research output: Contribution to journal › Article › peer-review

151. Published

     Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations.

     Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Nov 2007, In: Value in Health. 10, 6, p. 498-509

     Research output: Contribution to journal › Article › peer-review

152. Published

     Methods for the collection of resource use data within clinical trials: A systematic review of studies funded by the UK Health Technology Assessment Program

     Ridyard, C. H. & Hughes, D., 1 Dec 2010, In: Value in Health. 13, 8, p. 867-872

     Research output: Contribution to journal › Article › peer-review

153. Published

     Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT

     Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Bostock, J., Hay, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. & Williamson, P. R., Apr 2021, In: Health Technology Assessment. 25, 24, 86 p.

     Research output: Contribution to journal › Article › peer-review

154. Published

     Multiple imputation of multiple multi-item scales when a full imputation model is infeasible

     Hughes, D., Plumpton, C. O., Morris, T., Hughes, D. A. & White, I. R., 26 Jan 2016, In: BMC Research Notes. 9, 45, p. 1-15

     Research output: Contribution to journal › Article › peer-review

155. Published

     Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial

     Brogan, P. A., Arch, B., Hickey, H., Anton, J., Iglesias, E., Baildam, E., Mahmood, K., Cleary, G., Moraitis, E., Papadopoulou, C., Beresford, M. W., Riley, P., Demir, S., Ozen, S., Culeddu, G., Hughes, D., Dolezalova, P., Hampson, L., Whitehead, J., Jayne, D., Ruperto, N., Tudor-Smith, C. & Eleftheriou, D., Sept 2021, In: Arthritis and Rheumatology. 73, 9, p. 1673-1682

     Research output: Contribution to journal › Article › peer-review

156. Published

     NICE and new: appraising innovation.

     Hughes, D., Ferner, R. E., Hughes, D. A. & Aronson, J. K., 5 Jan 2010, In: British Medical Journal. 340, p. b5493

     Research output: Contribution to journal › Article › peer-review

157. Published

     NICE recommendations: why no disinvestment recommendations to offset investment decisions?

     Hughes, D., Tuersley, L. V., Hughes, D. A., Wood, E. M. & Tuersley, L., 19 May 2015, In: BMJ. 350

     Research output: Contribution to journal › Article › peer-review

158. Published

     New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes

     Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., May 2018, In: Pharmacoeconomics. 36, 5, p. 613-624 12 p.

     Research output: Contribution to journal › Article › peer-review

159. Published

     New advice on switching antiepileptic drugs might be a false economy

     Holmes, E. A., Plumpton, C. O., Hughes, D., Holmes, E., Plumpton, C., Duerden, M., Marson, T. & Hughes, D. A., 16 Dec 2013, In: British Medical Journal. 347

     Research output: Contribution to journal › Article › peer-review

160. Published

     New drugs for old: disinvestment and NICE.

     Hughes, D., Hughes, D. A. & Ferner, R. E., 25 Feb 2010, In: British Medical Journal. 340, p. c572

     Research output: Contribution to journal › Article › peer-review

161. Published

     Non-compliance with antibiotic therapy for acute community infections: A global survey.

     Hughes, D., Pechere, J. C., Hughes, D. A., Kardas, P. & Cornaglia, G., 1 Mar 2007, In: International Journal of Antimicrobial Agents. 29, 3, p. 245-253

     Research output: Contribution to journal › Article › peer-review

162. Published

     Novel oral iron therapy for iron deficiency anaemia: How to value safety in a new drug?

     Culeddu, G., Su, L., Chen, Y., Pereira, D. I. A., Powell, J. J. & Hughes, D., Mar 2022, In: British Journal of Clinical Pharmacology. 88, 3, p. 1347-1357 11 p.

     Research output: Contribution to journal › Article › peer-review

163. Published

     Nurse-led vs. conventional physician-led follow-up for patients with cancer: systematic review

     Lewis, R., Neal, R. D., Williams, N. H., France, B., Wilkinson, C. E., Hendry, M., Russell, D., Russell, I., Hughes, D., Stuart, N. S. & Weller, D., 1 Apr 2009, In: Journal of Advanced Nursing. 65, 4, p. 706-723

     Research output: Contribution to journal › Article › peer-review

164. Published

     Opportunity costs and local health service spending decisions: a qualitative study from Wales

     Schaffer, S. K., Sussex, J., Hughes, D. & Devlin, N., 25 Mar 2016, In: BMC Health Services Research. 16, 103

     Research output: Contribution to journal › Article › peer-review

165. Published

     Orphan drugs revisited: author's response.

     Hughes, D. & Hughes, D. A., 1 May 2006, In: Quarterly Journal of Medicine. 99, 5, p. 350-351

     Research output: Contribution to journal › Article › peer-review

166. Published

     Parenting programme for parents of children at risk of developing conduct disorder: cost effectiveness analysis.

     Bywater, T. J., Hutchings, J. M., Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 31 Mar 2007, In: British Medical Journal. 334, 7595, p. 682-685

     Research output: Contribution to journal › Article › peer-review

167. Published

     Patient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs

     Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Mar 2019, In: Clinical Pharmacology and Therapeutics. 105, 3, p. 672-683 12 p.

     Research output: Contribution to journal › Article › peer-review

168. Accepted/In press

     Patient-led urate self-monitoring to improve clinical outcomes in people with gout: a feasibility study

     Michael, T. J. F., Wright, D. F. B., Chan, J. S., Coleshill, M. J., Aslani, P., Hughes, D., Day, R. O. & Stocker, S. L., 21 Feb 2024, (Accepted/In press) In: ACR Open Rheumatology.

     Research output: Contribution to journal › Article › peer-review

169. Published

     Patients' and healthcare professionals' views of cancer follow-up: systematic review

     Lewis, R., Neal, R. D., Hendry, M., France, B., Williams, N. H., Russell, D., Hughes, D. A., Russell, I., Stuart, N. S. A., Weller, D. & Wilkinson, C., Jul 2009, In: British Journal of General Practice. 59, 564, p. e248-e259

     Research output: Contribution to journal › Article › peer-review

170. Published

     Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

     Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A590

     Research output: Contribution to journal › Article › peer-review

171. Published

     Perceptions of European ME/CFS experts concerning knowledge and understanding of ME/CFS among primary care physicians in Europe: A report from the European ME/CFS Research Network (EUROMENE)

     Cullinan, J., Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 26 Feb 2021, In: Medicina. 57, 3, 208.

     Research output: Contribution to journal › Article › peer-review

172. Published

     Pharmacoeconomics: principles and relevance to the activities of drug and therapeutics committees.

     Hughes, D., Hughes, D. A. & Reynolds, D. J., 1 Oct 2009, In: Clinical Medicine. 9, 5, p. 490-492

     Research output: Contribution to journal › Article › peer-review

173. Published

     Pharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery

     Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Jul 2015, In: British Journal of Clinical Pharmacology. 80, 5, p. 1149-1159

     Research output: Contribution to journal › Article › peer-review

174. Published

     Pharmacogenetic tests: the need for a level playing field

     Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4

     Research output: Contribution to journal › Article › peer-review

175. Published

     Plasma Methylmalonic Acid Concentration in Folic Acid–Supplemented Depressed Patients with Low or Marginal Vitamin B-12: A Randomized Trial

     Carter, B., Zenasni, Z., Moat, S. J., Hudson, P. R., Russell, I. T., McCaddon, A., Whitaker, R., Pink, J., Roberts, S., Wilkinson, C., Hughes, D., Betson, E., Carr, D., Jorgenson, A., Pirmohamed, M., Williams, N., Lewis, H., Lloyd, K., Sylvesture, Y. & Tranter, R., Dec 2021, In: Journal of Nutrition. 151, 12, p. 3738-3745 8 p.

     Research output: Contribution to journal › Article › peer-review

176. Published

     Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone.

     Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, G., Watkins, W. A. & Ward, S., 1 Mar 2006, In: British Journal of Clinical Pharmacology. 61, 3, p. 289-300

     Research output: Contribution to journal › Article › peer-review

177. Published

     PrEP use, sexual behaviour, and PrEP adherence among men who have sex with men living in Wales prior to and during the COVID-19 pandemic

     Gillespie, D., Couzens, Z., de Bruin, M., Hughes, D., Jones, A., Ma, R., Williams, A., Wood, F. & Blee, K., Aug 2022, In: AIDS and Behavior. 26, 8, p. 2746-2757 12 p.

     Research output: Contribution to journal › Article › peer-review

178. Published

     Predicting "real world" effectiveness by integrating adherence with pharmacodynamic modelling.

     Hughes, D., Hughes, D. A. & Walley, T., 1 Jul 2003, In: Clinical Pharmacology and Therapeutics. 74, 1, p. 1-8

     Research output: Contribution to journal › Article › peer-review

179. Published

     Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research

     Holmes, E. A., Morrison, V. L. & Hughes, D., 8 Dec 2014, In: Value in Health. 17, 8, p. 863-876

     Research output: Contribution to journal › Article › peer-review

180. Published

     Predictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey

     Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Mar 2015, In: Value in Health. 18, 2, p. 206-216

     Research output: Contribution to journal › Article › peer-review

181. Published

     Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study

     Hughes, D. & Poletti-Hughes, J., 21 Oct 2016, In: PLoS ONE. 11, 10, e0164681.

     Research output: Contribution to journal › Article › peer-review

182. Published

     Psychometric properties of an adapted stigma scale and experiences of stigma associated with HIV pre-exposure prophylaxis use among men who have sex with men: a mixed methods study

     Gillespie, D. & Hughes, D., Jul 2023, In: AIDS and Behavior. 27, 7, p. 2397-2410 14 p.

     Research output: Contribution to journal › Article › peer-review

183. Published

     Public funding of drugs for orphan diseases

     Hughes, D. & Hughes, D. A., 11 Nov 2005, In: Value in Health. 8, 6, p. A192

     Research output: Contribution to journal › Article › peer-review

184. Published

     Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)

     Ridyard, C., Blair, J. & Hughes, D., Nov 2017, In: Value in Health. 20, 9, p. A481 - A482

     Research output: Contribution to journal › Article › peer-review

185. Published

     Quantitative evidence synthesis methods for the assessment of the effectiveness of treatment sequences for clinical and economic decision-making: a review and taxonomy of simplifying assumptions

     Lewis, R., Hughes, D., Sutton, AJ. & Wilkinson, C., Jan 2021, In: PharmacoEconomics. 39, 1, p. 25-61 37 p.

     Research output: Contribution to journal › Article › peer-review

186. Published

     Rare Disease Terminology and Definitions—A Systematic Global Review: Report of the ISPOR Rare Disease Special Interest Group

     Hughes, D., Richter, T., Nestler-Parr, S., Babela, R., Khan, Z. M., Tesoro, T., Molsen, E. & Hughes, D. A., 18 Aug 2015, In: Value in Health. 18, 6, p. 906-914

     Research output: Contribution to journal › Article › peer-review

187. Published

     Rare disease prevention and treatment: The need for a level playing field

     Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247

     Research output: Contribution to journal › Article › peer-review

188. Published

     Rationing of drugs for rare diseases.

     Hughes, D. & Hughes, D. A., 1 Jan 2006, In: Pharmacoeconomics. 24, 4, p. 315-316

     Research output: Contribution to journal › Article › peer-review

189. Published

     Reimbursement Decisions of the All Wales Medicines Strategy Group

     Hughes, D., Linley, W. G. & Hughes, D. A., 1 Sept 2012, In: PharmoEconomics. 30, 9, p. 779-794

     Research output: Contribution to journal › Article › peer-review

190. Published

     Renal transplant patients’ preference for the supply and delivery of immunosuppressants in Wales: A discrete choice experiment

     Hagemi, A., Plumpton, C. & Hughes, D., 2 Oct 2017, In: BMC Nephrology. 18, 305.

     Research output: Contribution to journal › Article › peer-review

191. Published

     Resource-Use Measurement Based on Patient Recall: Issues and Challenges for Economic Evaluation

     Thorn, J. C., Coast, J., Cohen, D., Hollingworth, W., Knapp, M., Noble, S. M., Ridyard, C. H., Wordsworth, S. & Hughes, D., 1 Jun 2013, In: Applied Health Economics and Health Policy. 11, 3, p. 155-161

     Research output: Contribution to journal › Article › peer-review

192. Published

     Seizure First Aid Training For people with Epilepsy (SAFE) frequently attending emergency departments and their significant others: results of a UK multi-centre randomised controlled pilot trial

     Noble, A. J., Snape, D., Nevitt, S., Holmes, E., Morgan, M., Smith, C. T., Hughes, D., Buchanan, M., McVicar, J., MacCallum, E., Goodacre, S., Rinsdale, L. & Marson, A. G., 16 Apr 2020, In: BMJ Open. 10, 4, e035516.

     Research output: Contribution to journal › Article › peer-review

193. Published

     Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project

     Noble, A. J., Morris, B., Dixon, P., Mathieson, A., Ridsdale, L., Morgan, M., Dickson, J., Goodacre, S., Jackson, M., Hughes, D., Marson, A. & Holmes, E., Apr 2024, In: Seizure: European Journal of Epilepsy. 118, p. 17-27

     Research output: Contribution to journal › Article › peer-review

194. Published

     Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT

     Mallucci, C. L., Jenkinson, M., Conroy, E. J., Hartley, J. C., Brown, M., Moitt, T., Dalton, J., Kearns, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 2 Apr 2020, In: Health Technology Assessment. 24, 17, 114 p.

     Research output: Contribution to journal › Article › peer-review

195. Published

     Societal perspective on access to publicly subsidised medicines: A cross sectional survey of 3080 adults in Australia

     Chim, L., Salkeld, G., Kelly, P., Lipworth, W., Hughes, D. & Stockler, M., 1 Mar 2017, In: PLoS ONE.

     Research output: Contribution to journal › Article › peer-review

196. Published

     Societal preferences for funding orphan drugs in the United Kingdom: An application of person trade off and discrete choice experiment methods

     Bourke, S. M., Plumpton, C. & Hughes, D., 9 May 2018, In: Value in Health. 21, 5, p. 538-546

     Research output: Contribution to journal › Article › peer-review

197. Published

     Societal views on NICE, cancer drugs fund and value-based pricing criteria for prioritising medicines: a cross-sectional survey of 4118 adults in Great Britain

     Hughes, D., Linley, W. G. & Hughes, D. A., 1 Aug 2013, In: Health Economics. 22, 8, p. 948-964

     Research output: Contribution to journal › Article › peer-review

198. Published

     Statistical Methods for Adjusting Estimates of Treatment Effectiveness for Patient Non-adherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Systematic Review of Methodological Papers

     Alshreef, A., Latimer, N., Tappenden, P., Wong, R., Hughes, D., Fotheringham, J. & Dixon, S., Nov 2019, In: Medical Decision Making. 39, 8, p. 910-925 16 p.

     Research output: Contribution to journal › Article › peer-review

199. Published

     Statistical comments are unfounded.

     Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Mar 2008, In: Value in Health. 11, 2, p. 346

     Research output: Contribution to journal › Article › peer-review

200. Published

     Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)

     Balabanova, S., Taylor, C., Sills, G., Burnside, G., Plumpton, C., Smith, P., Appleton, R., Leach, J. P., Johnson, M., Baker, G. A., Pirmohamed, M., Hughes, D., Williamson, P., Tudor-Smith, C. & Marson, A. G., 26 Aug 2020, In: BMJ Open. 10, 8, e040635.

     Research output: Contribution to journal › Article › peer-review

201. Published

     Study protocol for a randomised controlled trial of insulin delivery by continuous subcutaneous infusion compared to multiple daily injections

     Blair, J., Gregory, J., Hughes, D., Ridyard, C., Gamble, C., McKay, A., Didi, M., Thornborough, K., Bedson, E., Awoyale, L., Cwiklinski, E. & Peak, M., 16 Apr 2015, In: Trials. 16, 163.

     Research output: Contribution to journal › Article › peer-review

202. Published

     Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica

     Williams, N. H., Jenkins, A., Goulden, N., Hoare, Z., Hughes, D. A., Wood, E., Foster, N. E., Walsh, D. A., Carnes, D., Sparkes, V., Hay, E. M., Isaacs, J., Konstantinou, K., Morrissey, D., Karppinen, J., Genevay, S. & Wilkinson, C., 31 Oct 2017, In: Health Technology Assessment. 21, 60, p. 1-180 180 p.

     Research output: Contribution to journal › Article › peer-review

203. Published

     Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial

     Marsden, J., Kelleher, M., Gilvarry, E., Mitcheson, L., Bisla, J., Cape, A., Cowden, F., Day, E., Dewhurst, J., Evans, R., Hardy, W., Hearn, A., Kelly, J., Lowry, N., McCusker, M., Murphy, C., Murray, R., Myton, T., Quarshie, S., Vanderwaal, R., Wareham, A., Hughes, D. & Hoare, Z., Dec 2023, In: eClinicalMedicine. 66, 23 p., 102331.

     Research output: Contribution to journal › Article › peer-review

204. Published

     Supply-side cost-effectiveness thresholds: questions for evidence-based policy

     Sampson, C., Zamora, B., Watson, S., Cairns, J., Chalkidou, K., Cubi-Molla, P., Devlin, N., García-Lorenzo, B., Hughes, D., Leech, A. & Towse, A., Sept 2022, In: Applied Health Economics and Health Policy. 20, 5, p. 651-667

     Research output: Contribution to journal › Article › peer-review

205. Published

     Supporting People With Type 2 Diabetes in the Effective Use of Their Medicine Through Mobile Health Technology Integrated With Clinical Care to Reduce Cardiovascular Risk: Protocol for an Effectiveness and Cost-effectiveness Randomized Controlled Trial

     Farmer, A. J., Jones, L., Newhouse, N., Kenning, C., Williams, N., Chi, Y., Bartlett, K., Plumpton, C., McSharry, J., Cholerton, R., Holmes, E., Robinson, S., Allen, J., Gudgin, B., Velardo, C., Rutter, H., Horne, R., Tarassenko, L., Williams, V., Locock, L., Rea, R., Yu, L-M., Hughes, D., Bower, P. & French, D. P., 21 Feb 2022, In: JMIR Research Protocols. 11, 2, e32918.

     Research output: Contribution to journal › Article › peer-review

206. Published

     Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol

     Farmer, A. J., Allen, J., Bartlett, K., Bower, P., Chi, Y., French, D. P., Gudgin, B., Holmes, E., Horne, R., Hughes, D., Kenning, C., Locock, L., McSharry, J., Miles, L., Newhouse, N., Rea, R., Riga, J., Tarassenko, L., Velardo, C., Williams, N., Williams, V. & Yu, L-M., 29 Dec 2019, In: BMJ Open. 9, 12, e033504.

     Research output: Contribution to journal › Article › peer-review

207. E-pub ahead of print

     Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D pilot): results of a feasibility randomised trial

     SuMMiT-D Collaborative Group , 25 Jan 2024, (E-pub ahead of print) In: Pilot and Feasibility Studies. 10, 1, 15.

     Research output: Contribution to journal › Article › peer-review

208. Published

     Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation

     Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. G. & Williamson, P., 1 May 2021, In: The Lancet Rheumatology. 3, 5, p. e347-e356

     Research output: Contribution to journal › Article › peer-review

209. Published

     Systematic Review: Outcomes and adverse events from randomised trials in Crohn's disease

     Catt, H., Hughes, D., Kirkham, J. K. & Bodger, K., Apr 2019, In: Alimentary Pharmacology and Therapeutics. 49, 8, p. 978-996 19 p.

     Research output: Contribution to journal › Article › peer-review

210. Published

     TEOS: A framework for constructing operational definitions of medication adherence based on Timelines – Events – Objectives – Sources

     Dima, A. L., Allemann, S. S., Dunbar-Jacobs, J., Hughes, D., Vrijens, B. & Wilson, I., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2521-2533

     Research output: Contribution to journal › Article › peer-review

211. Published

     The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol

     Hughes, D., Jenkinson, M. D., Gamble, C., Hartley, J. C., Hickey, H., Hughes, D. A., Blundell, M., Griffiths, M. J., Solomon, T. & Malluci, C. L., 3 Jan 2014, In: Trials. 15, 14

     Research output: Contribution to journal › Article › peer-review

212. Published

     The Development of a Consistent Europe-Wide Approach to Investigating the Economic Impact of Myalgic Encephalomyelitis (ME/CFS): A Report from the European Network on ME/CFS (EUROMENE)

     Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 7 Apr 2020, In: Healthcare. 8, 2, 88.

     Research output: Contribution to journal › Article › peer-review

213. Published

     The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

     Hughes, D., Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Jan 2012, In: British Journal of Clinical Pharmacology. 73, 1, p. 66-76

     Research output: Contribution to journal › Article › peer-review

214. Published

     The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial

     Jenkinson, M. D., Javadpour, M., Haylock, B. J., Young, B., Gillard, H., Vinten, J., Bulbeck, H., Das, K., Farrell, M., Looby, S., Hickey, H., Preusser, M., Mallucci, C. L., Hughes, D., Gamble, C. & Weber, D. C., 14 Nov 2015, In: Trials. 16

     Research output: Contribution to journal › Article › peer-review

215. Published

     The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

     Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1363-1374

     Research output: Contribution to journal › Article › peer-review

216. Published

     The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

     Marson, A., Burnside, G., Appleton, R., Leach, J. P., Sills, G., Tudor-Smith, C., Plumpton, C., Hughes, D., Williamson, P., Baker, G. A., Balabanova, S., Taylor, C., Brown, R., Hindley, D., Howell, S., Maguire, M., Mohanraj, R. & Smith, P. E., 10 Apr 2021, In: The Lancet. 397, 10282, p. 1375-1386

     Research output: Contribution to journal › Article › peer-review

217. Published

     The development of a QALY measure for epilepsy: NEWQOL-6D

     Hughes, D., Mulhern, B., Rowen, D., Jacoby, A., Marson, T., Snape, D., Hughes, D. A., Latimer, N., Baker, G. A. & Brazier, J. E., 1 May 2012, In: Epilepsy and Behavior. 24, 1, p. 36-43

     Research output: Contribution to journal › Article › peer-review

218. Published

     The difference between effectiveness and efficacy of antimalarial drugs in Kenya.

     Hughes, D., Amin, A. A., Hughes, D. A., Marsh, V., Abuya, T. O., Kokwaro, G. O., Winstanley, P. A., Ochala, S. A. & Snow, R. W., 1 Sept 2004, In: Tropical Medicine and International Health. 9, 9, p. 967-974

     Research output: Contribution to journal › Article › peer-review

219. Published

     The impact of non-compliance on the cost-effectiveness of pharmaceuticals: A review of the literature.

     Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Oct 2001, In: Health Economics. 10, 7, p. 601-615

     Research output: Contribution to journal › Article › peer-review

220. Published

     The impact of parent treatment preference and other factors on recruitment: lessons learned from a paediatric epilepsy randomised controlled trial

     Carter, B., Bray, L., Al-Najjar, N., Tort Piella, A., Smith, C. T., Spowart, C., Collingwood, A., Crudgington, H., Currier, J., Hughes, D., Wood, E., Martin, R., Morris, C., Roberts, D., Rouncefield-Swales, A., Sutherland, H., Watson, V., Cook, G., Wiggs, L., Gringas, P. & Pal, D., 6 Feb 2023, In: Trials. 24, 1, 83.

     Research output: Contribution to journal › Article › peer-review

221. Published

     The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies

     Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Jan 2000, In: Value in Health. 3, 5, p. 373

     Research output: Contribution to journal › Article › peer-review

222. Published

     The new and non-transparent Cancer Drugs Fund

     Wood, E. & Hughes, D., Jan 2020, In: PharmacoEconomics. 38, 1, p. 1-4

     Research output: Contribution to journal › Article › peer-review

223. Published

     The problem of orphan drugs

     Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Nov 2010, In: British Medical Journal. 341, p. 335-341

     Research output: Contribution to journal › Article › peer-review

224. Published

     The role of prevention in reducing the economic impact of ME/CFS in Europe: A report from the socioeconomics working group of the European Network on ME/CFS (EUROMENE).

     Pheby, D. F. H., Araja, D., Berkis, U., Brenna, E., Cullinan, J., de Korwin, J-D., Gitto, L., Hughes, D., Hunter, R. M., Trépel, D. & Wang-Steverding, X., 16 Apr 2021, In: Medicina. 57, 4, 388.

     Research output: Contribution to journal › Article › peer-review

225. Published

     Trends and influences on use of antidiabetic drugs in England, 1992-2003.

     Walley, T., Hughes, D. & Kendall, H., 1 Nov 2005, In: Pharmacoepidemiology and Drug Safety. 14, 11, p. 769-773

     Research output: Contribution to journal › Article › peer-review

226. Published

     Understanding medication compliance and persistence from an economics perspective

     Hughes, D., Elliot, R. A., Shinogle, J. A., Peele, P., Bhosle, M. & Hughes, D. A., 1 Jan 2008, In: Value in Health. 11, 4, p. 600-610

     Research output: Contribution to journal › Article › peer-review

227. Published

     Use Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients

     Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A580

     Research output: Contribution to journal › Article › peer-review

228. Published

     Using Routinely Recorded Data in a UK RCT: A Comparison to Standard Prospective Data Collection Methods

     Powell, G., Bonnett, L., Tudor-Smith, C., Hughes, D., Williamson, P. R. & Marson, A. G., 5 Jul 2021, In: Trials. 22, 1, 429.

     Research output: Contribution to journal › Article › peer-review

229. Published

     Using Routinely Recorded Data in the UK to Assess Outcomes in a Randomised Controlled Trial: The Trials of Access

     Powell, G., Bonnett, L., Smith, C. T., Hughes, D., Williamson, P. & Marson, A., 23 Aug 2017, In: Trials. 18, 11 p., 389.

     Research output: Contribution to journal › Article › peer-review

230. Published

     Utilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project

     Totton, N., Julious, S., Hughes, D., Cook, J., Biggs, K., Coates, L., Cook, A., Hewitt, C. & Day, S., 19 Jan 2021, In: Trials. 22, 68.

     Research output: Contribution to journal › Article › peer-review

231. Published

     Valuations of epilepsy-specific health states: a comparison of patients with epilepsy and the general population

     Hughes, D., Mulhern, B., Rowen, D., Snape, D., Jacoby, A., Marson, T., Hughes, D. A., Baker, G. & Brazier, J., 1 Jul 2014, In: Epilepsy and Behavior. 36, p. 12-17

     Research output: Contribution to journal › Article › peer-review

232. Published

     Value assessment and quantitative benefit-risk modelling of biosimilar infliximab for Crohn’s disease

     Catt, H., Bodger, K., Hughes, D. & Kirkham, J. J., Dec 2019, In: PharmacoEconomics. 37, 12, p. 1509-1523 15 p.

     Research output: Contribution to journal › Article › peer-review

233. Published

     Value of improving patient safety: Health-economic considerations for Rapid Response Systems – a Rapid Review of the Literature and Expert Round Table

     Subbe, C., Hughes, D., Lewis, S., Holmes, E., Kalkman, C. J., So, R. K., Tranka, S. & Welch, J., 17 Apr 2023, In: BMJ Open. 13, 4, e065819.

     Research output: Contribution to journal › Article › peer-review

234. Published

     Value-Based Pricing: Incentive for Innovation or Zero Net Benefit?

     Hughes, D. & Hughes, D. A., 1 Sept 2011, In: Pharmacoeconomics. 29, 9, p. 731-735

     Research output: Contribution to journal › Article › peer-review

235. Published

     Warfarin pharmacogenetics: Economic considerations.

     Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Jan 2007, In: Pharmacoeconomics. 25, 11, p. 899-902

     Research output: Contribution to journal › Article › peer-review

236. E-pub ahead of print

     We need to talk about values: a proposed framework for the articulation of normative reasoning in health technology assessment

     Hughes, D., 27 Sept 2023, (E-pub ahead of print) In: Health Economics, Policy and Law.

     Research output: Contribution to journal › Article › peer-review

237. Published

     What influences persistence with medicines? A multinational discrete choice experiment of 2549 patients

     Holmes, E. A., Morrison, V. L. & Hughes, D., Aug 2016, In: British Journal of Clinical Pharmacology. 82, 2, p. 522-531

     Research output: Contribution to journal › Article › peer-review

238. Published

     What really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK

     Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Jun 2019, In: Epilepsy and Behavior. 95, p. 181-191

     Research output: Contribution to journal › Article › peer-review

239. Published

     What should patients do if they miss a dose? A systematic review of patient information leaflets and summaries of product characteristics

     Albassam, A. & Hughes, D., Feb 2021, In: European Journal of Clinical Pharmacology. 77, 2, p. 251-260 10 p.

     Research output: Contribution to journal › Article › peer-review

240. Published

     When drugs don't work - Economic assessment of enhancing compliance with interventions supported by electronic monitoring devices.

     Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Pharmacoeconomics. 25, 8, p. 621-635

     Research output: Contribution to journal › Article › peer-review

241. Published

     ‘Seizure First Aid Training’ for people with epilepsy who attend emergency departments, and their family and friends: study protocol for intervention development and a pilot randomised controlled trial

     Noble, A. J., Marson, A. G., Tudur-Smith, C., Morgan, M., Hughes, D., Goodacre, S. & Ridsdale, L., 24 Jul 2015, In: BMJ Open. 5, 7

     Research output: Contribution to journal › Article › peer-review

242. Letter › Research › Peer-reviewed
243. Published

     2016 Prof. John Urquhart Obituary

     Breckenridge, A. & Hughes, D., Aug 2016, In: British Journal of Clinical Pharmacology. 82, 2, p. 573

     Research output: Contribution to journal › Letter › peer-review

244. Published

     Cost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.

     Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25

     Research output: Contribution to journal › Letter › peer-review

245. Published

     Do guidelines for treating chest disease in children use Cochrane reviews effectively? A systematic review

     Prayle, A., Cox, T., Smith, S. J., Rycroft-Malone, J., Thomas, K. S., Hughes, D. & Smyth, A. R., Jul 2018, In: Thorax. 73, 7, p. 670-673

     Research output: Contribution to journal › Letter › peer-review

246. Published

     Involving colleagues can be challenging

     Fargher, E. & Hughes, D., 2 Apr 2011, In: Pharmaceutical Journal. 286, p. 404

     Research output: Contribution to journal › Letter › peer-review

247. Published

     Letter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma

     Jenkinson, M., Weber, D., Haylock, B., Sherratt, F., Young, B., Weller, M., Bulbeck, H., Culeddu, G., Hughes, D., Brain, A., Das, K., Preusser, M., Francis, P. & Gamble, C., 17 Aug 2018, In: Journal of Neurology, Neurosurgery and Psychiatry.

     Research output: Contribution to journal › Letter › peer-review

248. Published

     Management of Patients Symptomatically Unresponsive to Levothyroxine: Natural Desiccated Thyroid Extract or the Combination of Levothyroxine and Liothyronine? A Research Priority

     Hughes, D., Livingston, M. & Heald, A., Sept 2020, In: Experimental and Clinical Endocrinology & Diabetes . 128, 9, p. 596-598

     Research output: Contribution to journal › Letter › peer-review

249. Published

     Medicines Shortages in the United Kingdom

     Hughes, D., Oct 2019, In: Clinical Pharmacology and Therapeutics. 106, 4, p. 712

     Research output: Contribution to journal › Letter › peer-review

250. Published

     Taxonomy for methods of resource use measurement

     DIRUM Team, 23 Jan 2015, In: Health Economics. 24, 3, p. 372-378

     Research output: Contribution to journal › Letter › peer-review

251. Comment/debate › Research › Not peer-reviewed
252. Published

     Cost-effectiveness of HLA-B*15:02 screening in Malaysia

     Plumpton, C. & Hughes, D., Oct 2017, In: British Journal of Dermatology. 177, 4, p. 904-905

     Research output: Contribution to journal › Comment/debate

253. Comment/debate › Research › Peer-reviewed
254. Published

     Challenges for economic evaluation of strategies to contain antimicrobial resistance

     Holmes, E. & Hughes, D., 27 Sept 2019, In: Antibiotics. 8, 4, 8 p., 166.

     Research output: Contribution to journal › Comment/debate › peer-review

255. Published

     Pharmacogenomics spotlight commentary: From the United Kingdom to global populations

     Magavern, E. F., Daly, A. K., Gilchrist, A. & Hughes, D., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4546-4548 3 p., 14917.

     Research output: Contribution to journal › Comment/debate › peer-review

256. Editorial › Research › Peer-reviewed
257. Published

     Improving Medication Adherence Research Reporting: European Society for Patient Adherence, Compliance and Persistence Medication Adherence Reporting Guideline

     de Geest, S., Zullig, L., Dunbar-Jacobs, J., Hughes, D., Wilson, I. & Vrijens, B., Jun 2019, In: Journal of Cardiovascular Nursing. 34, 3, p. 199-200

     Research output: Contribution to journal › Editorial › peer-review

258. Published

     Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

     de Geest, S., Zullig, L. L., Dunbar-Jacob, J., Hughes, D., Wilson, I. & Vrijens, B., 1 Apr 2019, In: European Journal of Cardiovascular Nursing. 18, 4, p. 258-259 2 p.

     Research output: Contribution to journal › Editorial › peer-review

259. Published

     Medication adherence research comes of age

     Wright, D. F. B., Sinnappah, K. A. & Hughes, D., Jul 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 1914-1917

     Research output: Contribution to journal › Editorial › peer-review

260. Published

     Medication adherence – key considerations for clinical pharmacologists

     Hughes, D., Apr 2020, In: British Journal of Clinical Pharmacology. 86, 4, p. 628-629 2 p.

     Research output: Contribution to journal › Editorial › peer-review

261. Meeting Abstract › Research › Peer-reviewed
262. Published

     Cost effectiveness analysis of treatments for children with uncontrolled asthma symptoms despite taking inhaled corticosteroids

     Culeddu, G., Sinha, I., Donegan, S., Maden, M., Cividini, S., Rose, K., Fulton, O., Turner, S., Tudor-Smith, C. & Hughes, D., 27 Oct 2023, In: European Respiratory Journal. 62 , Supplement 67, PA 523.

     Research output: Contribution to journal › Meeting Abstract › peer-review

263. Published

     Patient preferences for outcomes in clinical trials: implications for medicines optimization

     Holmes, E., Marson, A. G. & Hughes, D., 8 May 2017, In: Trials. 18 (Suppl 1), O18, p. 192 1 p.

     Research output: Contribution to journal › Meeting Abstract › peer-review

264. Chapter › Research › Not peer-reviewed
265. Published

     Approaches to pharmacoeconomic analysis

     Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 101-126

     Research output: Chapter in Book/Report/Conference proceeding › Chapter

266. Published

     Drug evaluation and pharmocoeconomics.

     Hughes, D., Krska, J., Hughes, D. A., Winfield, A. J. (ed.), Rees, J. A. (ed.) & Smith, I. (ed.), 1 Jan 2009, Pharmaceutical Practice: 4th Edition.. 2009 ed. Churchill Livingstone, p. 185-198

     Research output: Chapter in Book/Report/Conference proceeding › Chapter

267. Published

     Health economic aspects of patient non-compliance

     Hughes, D., Hughes, D. A., Davies, M. (ed.) & Kermani, F. (ed.), 1 Jan 2006, Patient Compliance: Sweetening the Pill. 2006 ed. Gower Publishing, p. 23-40

     Research output: Chapter in Book/Report/Conference proceeding › Chapter

268. Published

     Modelling in health economics

     Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 141-154

     Research output: Chapter in Book/Report/Conference proceeding › Chapter

269. Published

     The future challenges

     Hughes, D., Hughes, D. A., Walley, T. (ed.), Haycox, A. (ed.), Boland, A. (ed.) & Breckenridge, A. (ed.), 1 Jan 2004, Pharmacoeconomics. 2004 ed. Adis International, p. 167-174

     Research output: Chapter in Book/Report/Conference proceeding › Chapter

270. Chapter › Research › Peer-reviewed
271. Published

     Review of resource-use measures in UK economic evaluations

     Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (eds.). University of Kent, Canterbury, p. 22-31 10 p.

     Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

272. Paper › Research › Not peer-reviewed
273. Published

     A parenting programme for children at risk of developing conduct disorder: A cost-effectiveness analysis

     Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 1 May 2007.

     Research output: Contribution to conference › Paper

274. Published

     A prototype agent-based model of antimalarial drug compliance

     Hughes, D., McKean, J., Rahlf, S., Shorter, H., Barnish, G., Paton, R., McBurney, P., Hughes, D. A. & Hastings, I., 1 Aug 2007.

     Research output: Contribution to conference › Paper

275. Published

     A single centre open phase IV study to evaluate the safety and tolerability of chlorproguanil-dapsone when dosed by defined height bands

     Hughes, D., Makanga, M., Winstanley, P. & Hughes, D. A., 1 Nov 2004.

     Research output: Contribution to conference › Paper

276. Published

     A systematic review and empirical analysis of the relation between dose and duration of drug action.

     Hughes, D., Hughes, D. A. & Aronson, J. K., 1 Jan 2009, p. TP40.

     Research output: Contribution to conference › Paper

277. Published

     Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

     Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Sept 2003.

     Research output: Contribution to conference › Paper

278. Published

     Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

     Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Nov 2003.

     Research output: Contribution to conference › Paper

279. Published

     Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

     Hughes, D. & Hughes, D. A., 1 Jun 2003.

     Research output: Contribution to conference › Paper

280. Published

     Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

     Hughes, D. & Hughes, D. A., 1 May 2003.

     Research output: Contribution to conference › Paper

281. Published

     Accurate and practical dosing of African populations using a height, weight and age model designed for lapdap

     Hughes, D., Hughes, D. A. & Bagust, A., 1 Nov 2002.

     Research output: Contribution to conference › Paper

282. Published

     Adherence with HAART: pharmacoeconomic considerations

     Hughes, D. & Hughes, D. A., 1 Jun 2007.

     Research output: Contribution to conference › Paper

283. Published

     Adverse drug reactions in economic evaluations

     Hughes, D. & Hughes, D. A., 1 Jul 2007.

     Research output: Contribution to conference › Paper

284. Published

     Adverse drug reactions in economic evaluations

     Hughes, D. & Hughes, D. A., 1 Mar 2007.

     Research output: Contribution to conference › Paper

285. Published

     Adverse drug reactions: analysis by regulatory authorities and by economists

     Hughes, D. & Hughes, D. A., 1 Apr 2007.

     Research output: Contribution to conference › Paper

286. Published

     Assessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients

     Hughes, D. & Hughes, D. A., 1 May 2007.

     Research output: Contribution to conference › Paper

287. Published

     Assessing the association between compliance and therapeutic failure for antiretroviral drugs in HIV positive patients

     Hughes, D., 1 Mar 2007.

     Research output: Contribution to conference › Paper

288. Published

     Assessment, Determinants & Economics of Medication Compliance & Persistence Forum.

     Hughes, D., Hughes, D. A., Gwadry-Sridhar, F. & Manias, E., 1 Jan 2009.

     Research output: Contribution to conference › Paper

289. Published

     Back to basics: what is the relationship between dose and duration of drug action?

     Hughes, D. & Hughes, D. A., 1 May 2006.

     Research output: Contribution to conference › Paper

290. Published

     Biological agents for the management of Crohn's disease in adults: a systematic review, meta-analysis and multiple treatment comparison

     Hughes, D., Hughes, D. A., Kikuchi, T. & Bodger, K., 1 May 2007.

     Research output: Contribution to conference › Paper

291. Published

     Biosimilars: Evidential standards for health technology assessment.

     Hughes, D. & Hughes, D. A., 1 Jan 2009.

     Research output: Contribution to conference › Paper

292. Published

     Biosimilars: Evidential standards for health technology assessment.

     Hughes, D. & Hughes, D. A., 1 Jan 2009.

     Research output: Contribution to conference › Paper

293. Published

     Clinical and econnomic importance of completion of therapy in the treatment of LRTIs

     Hughes, D. & Hughes, D. A., 1 Sept 2006.

     Research output: Contribution to conference › Paper

294. Published

     Comparisons between the medication possession ratio (MPR) and gaps measures of medication compliance: are we selling ourselves short by relying on the MPR?

     Hughes, D., Nichol, M., Manias, E., Hughes, D. A. & Schabert, V. F., 1 Jan 2009.

     Research output: Contribution to conference › Paper

295. Published

     Cost of non-compliance and non-persistence with medications for diabetes mellitus

     Hughes, D., Salas, M., Hughes, D. A., Lebmeier, M. & Vardeva, K., 1 Aug 2007.

     Research output: Contribution to conference › Paper

296. Published

     Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

     Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

     Research output: Contribution to conference › Paper

297. Published

     Cost-effectiveness analysis of infliximab and adalimumab for Crohn's disease.

     Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Apr 2008.

     Research output: Contribution to conference › Paper

298. Published

     Cost-effectiveness considerations in pharmacogenetics.

     Hughes, D. & Hughes, D. A., 1 Jan 2008.

     Research output: Contribution to conference › Paper

299. Published

     Cost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease

     Hughes, D. & Hughes, D. A., 1 Nov 2003.

     Research output: Contribution to conference › Paper

300. Published

     Cost-utility analysis of on-demand rabeprazole and esomeprazole for non-erosive reflux disease

     Hughes, D. & Hughes, D. A., 1 Nov 2003.

     Research output: Contribution to conference › Paper

301. Published

     Costs of non-compliance to antipsychotic medications among patients with schizophrenia.

     Hughes, D., Hughes, D. A., Salas, M., Zuluaga, A., Cowell, W., Lebmeier, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 May 2008.

     Research output: Contribution to conference › Paper

302. Published

     Current assessment of risk-benefit by regulators: Is it time to introduce decision analyses?

     Hughes, D., Hughes, D. A., Pirmohamed, M. & Bayoumi, A., 1 Aug 2007.

     Research output: Contribution to conference › Paper

303. Published

     Drug compliance and pharmaceconomics

     Hughes, D. & Hughes, D. A., 1 Dec 2003.

     Research output: Contribution to conference › Paper

304. Published

     Economic considerations for market access of new health technologies: A case study of pharmacogenetic testing

     Hughes, D. & Hughes, D. A., 1 Feb 2008.

     Research output: Contribution to conference › Paper

305. Published

     Economic considerations for pharmacogenetic testing

     Hughes, D. & Hughes, D. A., 1 Jun 2008.

     Research output: Contribution to conference › Paper

306. Published

     Economic evaluation during early (phase II) trials

     Hughes, D. & Hughes, D. A., 1 Nov 2002.

     Research output: Contribution to conference › Paper

307. Published

     Economic evaluation of infliximab and adalimumab for Crohn's disease.

     Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 Jan 2009.

     Research output: Contribution to conference › Paper

308. Published

     Economic evaluation of on-demand maintenance therapy with proton pump inhibitors in patients with symptomatic gastroesophageal reflux disease - a Monte-Carlo analysis for Italy

     Hughes, D., Hughes, D. A., Marchetti, M. & Colombo, G., 1 Oct 2004.

     Research output: Contribution to conference › Paper

309. Published

     Economic evaluation of steroid injections (methylprednisolone) in the treatment of Morton's neuroma: patient-blind randomised trial

     Hughes, D., Thomson, C., Beggs, I., Martin, D., McCaldin, D., Russell, D., Edwards, R. T., Hughes, D. A., Yeo, S. T., Russell, I. T. & Gibson, T. N., 1 Mar 2007.

     Research output: Contribution to conference › Paper

310. Published

     Effects of the abolition of prescription charges in Wales: A preliminary analysis

     Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

     Research output: Contribution to conference › Paper

311. Published

     Eliciting patients' preferences using a discrete choice experiment questionnaire: the role played by qualitative data in questionnaire design

     Hughes, D., Longo, M., Hughes, D. A., Myles, S. & Lisles, C., 1 Mar 2006.

     Research output: Contribution to conference › Paper

312. Published

     Empirical analysis of the relationship between dose and duration of drug action

     Hughes, D. & Hughes, D. A., 1 Jun 2005.

     Research output: Contribution to conference › Paper

313. Published

     Engaging with the MRC Methodology Hubs – NWHTMR.

     Hughes, D. & Hughes, D. A., 1 Jan 2009.

     Research output: Contribution to conference › Paper

314. Published

     Enhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.

     Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Jan 2010.

     Research output: Contribution to conference › Paper

315. Published

     Factors influencing user choices to visit either general practitioners or community pharmacists for minor ailments – a discrete choice experiment

     Hughes, D., Hughes, D. A., Myles, S., Longo, M., Lisles, C. & Hood, K., 1 May 2007.

     Research output: Contribution to conference › Paper

316. Published

     Falls and hip-fractures: A cost-effectiveness analysis of risk assessment and interventions for community-dwelling older people

     Hughes, D., Gwynne, D., Hughes, D. A. & Edwards, R. T., 1 Mar 2007.

     Research output: Contribution to conference › Paper

317. Published

     Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

     Hughes, D. & Hughes, D. A., 1 May 2007.

     Research output: Contribution to conference › Paper

318. Published

     Feasibility, validity and reliability of the Welsh EQ-5D health status questionnaire

     Hughes, D., 1 Mar 2007.

     Research output: Contribution to conference › Paper

319. Published

     From efficacy to cost-effectiveness: Impact of patient compliance

     Hughes, D. & Hughes, D. A., 1 Feb 2008.

     Research output: Contribution to conference › Paper

320. Published

     From efficacy to cost-effectiveness: accounting for non-compliance in pharmacoeconomics

     Hughes, D. & Hughes, D. A., 1 May 2002.

     Research output: Contribution to conference › Paper

321. Published

     From efficacy to effectiveness and cost-effectiveness: modelling possibilities

     Hughes, D. & Hughes, D. A., 1 Nov 2004.

     Research output: Contribution to conference › Paper

322. Published

     Health and economic outcomes: Why compliance matters

     Hughes, D. & Hughes, D. A., 1 Apr 2006.

     Research output: Contribution to conference › Paper

323. Published

     Impact of non-compliance on the clinical and cost-effectiveness of statins

     Hughes, D. & Hughes, D. A., 1 Nov 2001.

     Research output: Contribution to conference › Paper

324. Published

     Impact of non-compliance on the cost-effectiveness of pharmaceuticals

     Hughes, D. & Hughes, D. A., 1 Nov 2002.

     Research output: Contribution to conference › Paper

325. Published

     Impact of pharmacogenetics on the costs of managing adverse events with warfarin: A prospective analysis.

     Hughes, D., Hughes, D. A., Al-Zubiedi, S., Hanson, A., Jorgensen, A. & Pirmohamed, M., 1 Jan 2009.

     Research output: Contribution to conference › Paper

326. Published

     Impact of the abolition of prescription charges in Wales: a multi-level modelling approach with application to time series dispensed rate data

     Hughes, D., Alam, F., Myles, S., Hughes, D. A., Dunstan, F., Routledge, P. & Cohen, D., 1 Sept 2007.

     Research output: Contribution to conference › Paper

327. Published

     Impact of the abolition of the prescription charge in Wales

     Hughes, D. & Hughes, D. A., 1 Nov 2008.

     Research output: Contribution to conference › Paper

328. Published

     Impact of the abolition of the prescription charge in Wales.

     Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.

     Research output: Contribution to conference › Paper

329. Published

     Impact of the abolition of the prescription charge in Wales.

     Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009.

     Research output: Contribution to conference › Paper

330. Published

     Impact of the abolition of the prescription charge in Wales.

     Hughes, D., Hughes, D. A., Alam, M. F., Cohen, D., Dunstan, F., Groves, S. & Routledge, P., 1 Jan 2009, p. O41.

     Research output: Contribution to conference › Paper

331. Published

     Incorporating measures of compliance and persistence in pharmacoeconomic evaluations

     Hughes, D., Hughes, D. A. & Cowell, W., 1 Nov 2005.

     Research output: Contribution to conference › Paper

332. Published

     Integrating compliance and persistence in health economics models

     Hughes, D. & Hughes, D. A., 1 Jan 2008.

     Research output: Contribution to conference › Paper

333. Published

     Interventions that enhance medication compliance and persistence: Theoretical grounding, and economic assessment

     Hughes, D., Hughes, D. A., Gwadry Sridhar, F., Elliott, R. & Cowell, W., 1 Oct 2007.

     Research output: Contribution to conference › Paper

334. Published

     Introduction to pharmaeconomics

     Hughes, D. & Hughes, D. A., 1 Jul 2004.

     Research output: Contribution to conference › Paper

335. Published

     Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments

     Hughes, D. & Hughes, D. A., 1 May 2006.

     Research output: Contribution to conference › Paper

336. Published

     Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment

     Hughes, D., Myles, S., Hughes, D. A., Longo, M. & Lisles, C., 1 Jun 2006.

     Research output: Contribution to conference › Paper

337. Published

     Methodological issues in the literature on costs of non-compliance in chronic diseases

     Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008.

     Research output: Contribution to conference › Paper

338. Published

     Modelling changes in first line antimalarial therapy

     Hughes, D. & Hughes, D. A., 1 Sept 2003.

     Research output: Contribution to conference › Paper

339. Published

     Orphan drug treatments: economic considerations

     Hughes, D. & Hughes, D. A., 1 Nov 2007.

     Research output: Contribution to conference › Paper

340. Published

     Patient compliance and persistence with prescribed medication: Measurement and health economic impact

     Hughes, D., Koncz, T., Hughes, D. A., Cleemput, I. & Annemans, L., 1 May 2004.

     Research output: Contribution to conference › Paper

341. Published

     Patient compliance and pharmacoeconomics

     Hughes, D. & Hughes, D. A., 1 Nov 2002.

     Research output: Contribution to conference › Paper

342. Published

     Patient compliance and pharmacoeconomics

     Hughes, D. & Hughes, D. A., 1 Oct 2001.

     Research output: Contribution to conference › Paper

343. Published

     Pharmacoeconomic evaluations in Ireland, Scotland and Wales: A Celtic perspective on pharmaceutical assessment

     Hughes, D., Hughes, D. A., Drummond, M., Tolley, K. & Ryan, M., 1 Oct 2007.

     Research output: Contribution to conference › Paper

344. Published

     Pharmacoeconomic models that incorporate non-compliance

     Hughes, D. & Hughes, D. A., 1 Jul 2004.

     Research output: Contribution to conference › Paper

345. Published

     Pharmacoeconomics appraisals by the all Wales medicines strategy group

     Hughes, D. & Hughes, D. A., 1 Jul 2004.

     Research output: Contribution to conference › Paper

346. Published

     Pharmacoeconomics in Wales: functions of the all Wales medicines strategy group

     Hughes, D. & Hughes, D. A., 1 Apr 2004.

     Research output: Contribution to conference › Paper

347. Published

     Pharmacoeconomics of pharmacogenetic testing: azathioprine

     Hughes, D., McAllister, R. & Hughes, D. A., 1 Apr 2004.

     Research output: Contribution to conference › Paper

348. Published

     Pharmacokinetics, patient compliance and pharmaeconomics

     Hughes, D. & Hughes, D. A., 1 Jun 2005.

     Research output: Contribution to conference › Paper

349. Published

     Pharmacometric analysis of duration of drug action: implications for improved forgiveness to medication non-compliance

     Hughes, D., Hughes, D. A. & Walley, T., 1 Sept 2001.

     Research output: Contribution to conference › Paper

350. Published

     Physchiatrist prescribing preferences and attitudes toward promotion

     Hughes, D., Menkes, D., Davies, R. & Hughes, D. A., 1 Apr 2006.

     Research output: Contribution to conference › Paper

351. Published

     Population pharmacokinetics of warfarin: Intermin analysis of the Liverpool pharmacogenetic prospective cohort study

     Hughes, D., Matthews, I., Aarons, L., Al-Zubiedi, S., Hatch, E., Lane, S., Williamson, P., Kamali, F., Hughes, D. A. & Pirmohamed, M., 1 Nov 2007.

     Research output: Contribution to conference › Paper

352. Published

     Pragmatic trials - design features and implications for clinical decision making

     Hughes, D., Urdahl, H., Hughes, D. A. & Freemantle, N., 1 Aug 2000.

     Research output: Contribution to conference › Paper

353. Published

     Prescription fee exemption research study

     Hughes, D., Myles, S., Hughes, D. A., Routledge, P. & Wales, D. F., 1 Jun 2006.

     Research output: Contribution to conference › Paper

354. Published

     Public funding of drugs for orphan diseases

     Hughes, D. & Hughes, D. A., 1 Jul 2005.

     Research output: Contribution to conference › Paper

355. Published

     Public funding of drugs for orphan diseases

     Hughes, D. & Hughes, D. A., 1 Jan 2006.

     Research output: Contribution to conference › Paper

356. Published

     Public funding of drugs for orphan diseases

     Hughes, D. & Hughes, D. A., 1 Nov 2005.

     Research output: Contribution to conference › Paper

357. Published

     Public funding of drugs for orphan diseases

     Hughes, D. & Hughes, D. A., 1 Nov 2005.

     Research output: Contribution to conference › Paper

358. Published

     Public meetings of the NICE appraisals committee

     Hughes, D. & Hughes, D. A., 1 Dec 2007.

     Research output: Contribution to conference › Paper

359. Published

     Quantitative risk-benefit analysis

     Hughes, D. & Hughes, D. A., 1 May 2007.

     Research output: Contribution to conference › Paper

360. Published

     Rationing of drugs for rare diseases

     Hughes, D. & Hughes, D. A., 1 Apr 2006.

     Research output: Contribution to conference › Paper

361. Published

     Systematic review of follow-up of cancer in primary care verses secondary care: findings for breast and lung cancer

     Hughes, D., Lewis, R., Neal, R. D., France, B., Williams, N. H., Wilkinson, C., Russell, I. T., Russell, D., Hughes, D. A., Stuart, N. S. & Weller, D., 1 Mar 2007.

     Research output: Contribution to conference › Paper

362. Published

     The all wales medicines strategy group: assessments and appraisals

     Hughes, D. & Hughes, D. A., 1 Nov 2008.

     Research output: Contribution to conference › Paper

363. Published

     The assessment, determinants & economics of medication compliance & persistence

     Hughes, D., Hughes, D. A., Gwadry Sridhar, F. & Elliott, R., 1 Oct 2007.

     Research output: Contribution to conference › Paper

364. Published

     The cost-effectiveness of biological therapies for Crohn's disease: Markov cohort analyses incorporating UK patient-level cost data

     Hughes, D., Bodger, K., Kikuchi, T. & Hughes, D. A., 1 Mar 2008.

     Research output: Contribution to conference › Paper

365. Published

     The cost-effectiveness of biological therapies for Crohn's disease: markov cohot analyses incorporating UK patient-level cost data

     Hughes, D., Hughes, D. A., Bodger, K. & Kikuchi, T., 1 May 2008.

     Research output: Contribution to conference › Paper

366. Published

     The economics of evergreening.

     Hughes, D. & Hughes, D. A., 1 Jan 2009.

     Research output: Contribution to conference › Paper

367. Published

     The effect of compliance upon clinical effectiveness of chlorproguanil-dapsone (CD) and artemether-lumefantrine (AL) when compared to sulfadoxine-pyrimethamine (SP) for the treatment of uncomplicated falcipaum malaria in Malawi - a randomised controlled trial

     Hughes, D., Bell, D. J., Wootton, D., Mukaka, M., Montgomery, J., Kayange, N., Chimpeni, P., Zijlstra, E., Hughes D.A., N. V., Molyneux M.E.*, N. V., Ward, S. A., Winstanley, P. A. & Lalloo, D. G., 1 Nov 2007.

     Research output: Contribution to conference › Paper

368. Published

     The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies

     Hughes, D., Hughes, D. A., Bagust, A., Haycox, A. & Walley, T., 1 Nov 2000.

     Research output: Contribution to conference › Paper

369. Published

     The pharmacokinetic profile of Warfarn: a systematic review

     Hughes, D., Al-Zubiedi S.*, N. V., Hughes D.A., N. V. & Pirmohamed, M., 1 Dec 2007.

     Research output: Contribution to conference › Paper

370. Published

     The population pharmacokinetics of lapdap

     Hughes, D., Ward, S., Simpson, J., Aarons, L., Szwandt, S. & Hughes, D. A., 1 Nov 2002.

     Research output: Contribution to conference › Paper

371. Published

     Ultra-long acting pharmaceuticals: Do they result in better outcomes, and at an acceptable cost?

     Hughes, D. & Hughes, D. A., 1 Nov 2006.

     Research output: Contribution to conference › Paper

372. Published

     Use of PK-PD modelling to predict the impact of non-compliance

     Hughes, D. & Hughes, D. A., 1 Nov 2003.

     Research output: Contribution to conference › Paper

373. Published

     What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?

     Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.

     Research output: Contribution to conference › Paper

374. Paper › Research › Peer-reviewed
375. Published

     A Systematic Review of Patient Preferences for Subcutaneous Medications

     Ridyard, C., Dawoud, D. & Hughes, D., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

376. Published

     Identification Of Items For A Standardised Resource-Use Measure: Review Of Current Instruments

     Thorn, J. C., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S. & Hollingworth, W., Nov 2015.

     Research output: Contribution to conference › Paper › peer-review

377. Published

     Review of the Use of Resource Use Instruments Based on Patient Recall in Relation to Other Methods of Cost Estimation

     Ridyard, C. & Hughes, D., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

378. Published

     Review of the use of resource use instruments based on patient recall in relation to other methods of resource use estimation

     Ridyard, C. & Hughes, D., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

379. Published

     Screening log data can be used to inform protocol modifications, increasing patient recrutiment to a challanging clinical trial

     Blair, J., Awoyale, L., Thornborough, K., Peak, M., Didi, M., Bedson, E., Hughes, D., Ridyard, C., Tat, T. & Gregory, J., Nov 2013.

     Research output: Contribution to conference › Paper › peer-review

380. Poster › Research › Peer-reviewed
381. Published

     Carer-administration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARIAD)

     Wilkinson, C., Poolman, M., Roberts, J., Wee, B., Hiscock, J., Hughes, D., Nelson, A., Perkins, P., Johnstone, R. P., Reymond, E., Foster, B., O'Connor, J., Jones, S., Hoare, Z., Roberts, R., Byrne, A., Healy, S. & Lewis, P., 1 Sept 2017.

     Research output: Contribution to conference › Poster › peer-review

382. Published

     Comparison of regression methods for the cost effectiveness analysis of clinical trials with a small population size: the sycamore and folated trials

     Culeddu, G., Hughes, D. & Welton, N., 10 Jul 2017.

     Research output: Contribution to conference › Poster › peer-review

383. Published

     Core items for a standardised resource-use measure (ISRUM):expert Delphi consensus survey

     Thorn, J., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., 7 May 2017, p. P265. 1 p.

     Research output: Contribution to conference › Poster › peer-review

384. Published

     Health Economics Analysis Plans: Where Are We Now?

     Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 3 Nov 2016, p. A397. 1 p.

     Research output: Contribution to conference › Poster › peer-review

385. Published

     Health economics analysis plans: the current state of play

     Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 7 May 2017, p. P144. 1 p.

     Research output: Contribution to conference › Poster › peer-review

386. Published

     Patient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations

     Ridyard, C. & Hughes, D., 7 May 2017, p. P141. 1 p.

     Research output: Contribution to conference › Poster › peer-review

387. Abstract › Research › Peer-reviewed
388. Published

     Continuous subcutaneous insulin infusion compated to multiple daily injection regimens in children and yung people at diagnosis of type 1 diabetes: A pragmatic randomised controlled trial and economic evaluation (scipi trial)

     Blair, J., Mckay, A., Ridyard, C., Thornborough, K., Bedson, E., Peak, M., Didi, M., Annan, F., John, G., Hughes, D. & Gamble, C., Sept 2017, p. 22-23.

     Research output: Contribution to conference › Abstract › peer-review

389. Other › Research › Peer-reviewed
390. Published

     Cost-Effectiveness Analysis of Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa

     Culeddu, G., Brogan, P. A. & Hughes, D., 2021.

     Research output: Contribution to conference › Other › peer-review

391. Commissioned report › Research › Not peer-reviewed
392. Published

     A review of economic models for second-line chemotherapy in the management of advanced, metastatic breast cancer.

     Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

     Research output: Book/Report › Commissioned report

393. Published

     AWMSG criteria for appraising new medicines.

     Hughes, D. & Hughes, D. A., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

394. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Abacavir 600mg/lamivudine 300mg (Kivexa) in antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus infection in adults and adolescents from 12 years of age.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

395. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Alemtuzumab (MabCampath) for the treatment of patients with B-cell chronic lymphocytic leukaemia for whom fludarabine combination chemotherapy is not appropriate.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

396. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Ambrisentan (Volibris) for pulmonary arterial hypertension.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

     Research output: Book/Report › Commissioned report

397. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Anidulafungin (Ecalta) for the treatment of invasive candidiasis in adult non-neutropenic patients.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

     Research output: Book/Report › Commissioned report

398. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-experienced patients.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

399. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-naïve patients.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

400. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Buprenorphine/naloxone (Suboxone) as substitution treatment for opioid dependence.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

401. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Deferasirox (Exjade) for the treatment of chronic iron overload due to blood transfusions.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

402. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Docetaxel (Taxotere) for locally advanced squamous cell carcinoma of the head and neck.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

403. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Emtricitabine/tenofovir DF (Truvada)

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

404. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Epoetin delta (Dynepo)

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

405. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for STEMI.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

406. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Fondaparinux Sodium (Arixtra®) for UA/NSTEMI.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

407. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Icatibant (Firazyr) for symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults (with C1-esterase-inhibitor deficiency).

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

408. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Lenalidomide (Revlimid) for multiple myeloma.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

409. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Maraviroc (Celsentri) for treatment-experienced adults infected only with CCR5-tropic HIV-1.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

     Research output: Book/Report › Commissioned report

410. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Pegfilgrastim (Neulasta) for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy for malignancy.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

411. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Raltegravir (Isentress) in combination with other antiretroviral medicinal products for the treatment of human immunodeficiency virus (HIV-1) infection in treatment-experienced adult patients with evidence of HIV-1 replication despite ongoing antiretroviral therapy.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

412. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Rufinamide (Inovelon) for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS).

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

413. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Stiripentol (Diacomit) for use in conjunction with clobazam and valproate in patients with severe myoclonic epilepsy in infancy.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

414. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Tacrolimus (Advagraf) for the prophylaxis of transplant rejection in adult kidney or liver allograft recipients and the treatment of allograft rejection resistant to treatment with other immunosuppressive medicinal products in adult patients.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2009, 2009 ed. Unknown.

     Research output: Book/Report › Commissioned report

415. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Tenofovir disoproxil fumarate (Viread) for the treatment of hepatitis B.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

416. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Teriparatide (Forsteo) for the treatment of osteoporosis in men at increased risk of fracture.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

417. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Topotecan (Hycamtin®) for Small Cell Lung Carcinoma.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

418. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Trabectedin (Yondelis) for advanced soft tissue sarcoma.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

419. Published

     All Wales Medicines Strategy Group Final Appraisal Report - Ziconotide (Prialt) for the intrathecal treatment of severe, chronic pain.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

420. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Clofarabine (Evoltra)

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

421. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Co-careldopa intestinal gel (Duodopa).

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

422. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Darunavir (Prezista)

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

423. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Chronic, accelerated or blast phase CML.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

424. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Lymphoid blast CML and PH+ ALL.

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

425. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Dexrazoxane (Savene)

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

426. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Emtricitabine (Emtriva)

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

427. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Idursulfase (Elaprase)

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

428. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Parathyroid hormone (Preotact)

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

429. Published

     All Wales Medicines Strategy Group Final Appraisal Report – Tipranavir (Aptivus).

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

430. Published

     All Wales Medicines Strategy Group Final Assessment Report – Agalsidase alfa (Replagal)

     Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

431. Published

     Development of an economic model to evaluate the cost-effectiveness of rival therapies for treating Crohn’s disease.

     Hughes, D., Kikuchi, T., Bodger, K. & Hughes, D. A., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

432. Published

     Follow-up of cancer patients in primary care versus secondary care: systematic review.

     Hughes, D., Lewis, R., Neal, R., Williams, N., France, B., Wilkinson, C., Hendry, M., Russell, D., Hughes, D. A., Russell, I. T., Stuart, N. S. & Weller, D., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

433. Published

     Impact of non-compliance on the therapeutic coverage of oxybutynin – comparison of once- and twice-daily oral formulations.

     Hughes, D. & Hughes, D. A., 1 Jan 2002, 2002 ed. Unknown.

     Research output: Book/Report › Commissioned report

434. Published

     Impact of non-compliance on the therapeutic coverage of risperidone – comparison of long acting injectible with oral formulations.

     Hughes, D. & Hughes, D. A., 1 Jan 2002, 2002 ed. Unknown.

     Research output: Book/Report › Commissioned report

435. Published

     Improving Outcomes for People with Brain and Other CNS Tumours: Analysis of the Potential Economic Impact of the Guidance.

     Hughes, D., Linck, P., Priedane, E., Hughes, D. A. & Edwards, R. T., 1 Jan 2006, 2006 ed. Unknown.

     Research output: Book/Report › Commissioned report

436. Published

     Improving Outcomes for People with Sarcoma: Analysis of the Potential Economic Impact of the Guidance.

     Hughes, D., Linck, P., Hughes, D. A. & Edwards, R. T., 1 Jan 2006, 2006 ed. Unknown.

     Research output: Book/Report › Commissioned report

437. Published

     Improving Outcomes for People with Skin Tumours including Melanoma: Analysis of the Potential Economic Impact of the Guidance.

     Hughes, D., Linck, P., Hughes, D. A. & Edwards, R. T., 21 Feb 2006, Unknown.

     Research output: Book/Report › Commissioned report

438. Published

     Improving Outcomes in Children and Young People with Cancer: Analysis of the Potential Economic Impact of the Guidance.

     Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2005, 2005 ed. Unknown.

     Research output: Book/Report › Commissioned report

439. Published

     Internationalisation of cost-effectiveness model for on-demand use of proton pump inhibitors - Belgium.

     Hughes, D. & Hughes, D. A., 1 Jan 2004, 2004 ed. Unknown.

     Research output: Book/Report › Commissioned report

440. Published

     Internationalisation of cost-effectiveness model for on-demand use of proton pump inhibitors - Sweden.

     Hughes, D. & Hughes, D. A., 1 Jan 2005, 2005 ed. Unknown.

     Research output: Book/Report › Commissioned report

441. Published

     Investigating factors influencing user choices to visit either general practioners or community pharmacists in the management of minor ailments - piloting a discrete choice experiment.

     Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

442. Published

     Pharmacokinetic-Pharmacodynamic modelling of Lapdap (CPG-DDS) combination.

     Hughes, D., Hughes, D. A., Watkins, B. & Winstanley, P., 1 Jan 2001, 2001 ed. Unknown.

     Research output: Book/Report › Commissioned report

443. Published

     Policy on ultra-orphan drugs.

     Hughes, D. & Hughes, D. A., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

444. Published

     Public health interventions to promote mental well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

     Hughes, D., Windle, G., Hughes, D. A., Linck, P., Morgan, R., Burholt, V., Edwards, R. T., Reeves, C., Yeo, S. T., Woods, R. T. & Russell, I. T., 1 Jan 2007, 2007 ed. Unknown.

     Research output: Book/Report › Commissioned report

445. Published

     Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness.

     Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T., Morgan, R., Woods, R. T., Burholt, V., Edwards, R. T., Reeves, C. & Yeo, S. T., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

446. Published

     Public health interventions to promote well-being in people aged 65 and over: systematic review of effectiveness and cost-effectiveness: Evidence Tables.

     Hughes, D., Linck, P. G., Windle, G., Linck, P., Morgan, R., Hughes, D. A., Burholt, V., Reeves, C., Yeo, S. T., Woods, R. T., Edwards, R. T. & Russell, I. T., 1 Jan 2008, 2008 ed. Unknown.

     Research output: Book/Report › Commissioned report

447. Published

     The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies.

     Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

     Research output: Book/Report › Commissioned report

448. Published

     Welsh Health Economics Network (WHEN): Scoping Report.

     Hughes, D., Farr, A., O Ceilleachair, A., Cohen, D., Hughes, D. A. & Phillips, C., 1 Jan 2005, 2005 ed. Unknown.

     Research output: Book/Report › Commissioned report

449. Published

     What is the effectiveness and cost-effectiveness of interventions in reducing the harms for children and young people who have been exposed to domestic violence or abuse: a rapid review.

     Spencer, L., Hendry, A., Makanjuola, A., Pisavadia, K., Davies, J., Albustami, M., Anthony, B., Wilkinson, C., Fitzsimmons, D., Hughes, D., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 10 May 2023, 79 p.

     Research output: Book/Report › Commissioned report

450. Commissioned report › Research › Peer-reviewed
451. Published

     What innovations can address inequalities experienced by women and girls due to the COVID-19 pandemic across the different areas of life/domains: work, health, living standards, personal security, participation and education? Report number – RR00027 (January 2022). Gender Inequalities: COVID-19 initiatives

     Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Pisavadia, K., Davies, J., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 15 Jan 2022, Health and Care Research Wales.

     Research output: Book/Report › Commissioned report › peer-review

452. Other report › Research › Not peer-reviewed
453. Published

     RES00019. Wales COVID-19 Evidence Centre. A rapid evidence summary indicating the evidence of the inverse care law in social care in Wales and has this been exacerbated by the COVID-19 pandemic?

     Spencer, L., Hendry, A., Makanjuola, A., Hughes, D., Wilkinson, C., Pisavadia, K., Davies, J., Fitzsimmons, D. & Edwards, R. T., Feb 2022, Welsh Government. 33 p.

     Research output: Book/Report › Other report

454. Published

     RES00038. Wales COVID-19 Evidence Centre. A rapid evidence summary of the cost impact of Long COVID on employment and caring responsibilities

     Spencer, L., Hendry, A., Davies, J., Pisavadia, K., Hughes, D. & Edwards, R. T., May 2022, Welsh Government. 18 p.

     Research output: Book/Report › Other report

455. Other report › Research › Peer-reviewed
456. Published

     Have infection control and prevention measures resulted in any adverse outcomes for care home and domiciliary care residents and staff? Report number: RR_00018 (November 2021)

     Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 1 Nov 2021, 36 p.

     Research output: Book/Report › Other report › peer-review

457. Web publication/site › Research
458. Published

     Investigating factors influencing user choices to visit either general practitioners or community pharmacists in the management of minor ailments – piloting a discrete choice experiment

     Hughes, D., Hughes, D. A., Myles, S., Longo, M. & Lisles, C., 1 Mar 2008

     Research output: Non-textual form › Web publication/site

459. Review article › Research › Peer-reviewed
460. Published

     A Systematic Review of Economic Evaluations of Advanced Therapy Medicinal Products

     Lloyd Williams, H. & Hughes, D., Jun 2021, In: British Journal of Clinical Pharmacology. 87, 6, p. 2428-2443 16 p.

     Research output: Contribution to journal › Review article › peer-review

461. Published

     Evidence to support inclusion of pharmacogenetic biomarkers in randomised controlled trials

     Johnson, D., Jorgensen, A., Hughes, D. & Pirmohamed, M., 1 Sept 2019, In: Journal of Personalized Medicine. 9, 3, 19 p., 42.

     Research output: Contribution to journal › Review article › peer-review

462. Preprint › Research
463. Published

     The costs and cost-effectiveness of different service models of palliatice care, focusing on end of life care: A rapid review

     Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Gillen, E., Noyes, J., Fitzsimmons, D., Lewis, R., Cooper, A., Hughes, D., Edwards, R. T. & Edwards, A., 7 Mar 2024, MedRxiv, 118 p.

     Research output: Working paper › Preprint

464. Published

     What interventions or best practice are there to support people with Long COVID, or similar post-viral conditions or conditions characterised by fatigue, to return to normal activities: a rapid review

     Spencer, L., Hendry, A., Makanjuola, A., Anthony, B., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 28 Jan 2023, 34 p. (MedRxiv).

     Research output: Working paper › Preprint

465. Published

     What is the long-term impact of COVID-19 on the Health-Related Quality of Life of individuals with mild symptoms (or non-hospitalised): A rapid review

     Spencer, L., Hendry, A., Makanjuola, A., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 9 Sept 2022, Health and Care Research Wales, 47 p.

     Research output: Working paper › Preprint